Modulation of cystic fibrosis transmembrane conductance regulator (CFTR) activity and genistein binding by cytosolic pH

Journal of Biological Chemistry

Volumn 285, Issue 53, 2010, Pages 41591-41596

  Melani, Raffaella ^a   Tomati, Valeria ^a   Galietta, Luis J V ^a   Zegarra Moran, Olga ^a  

^a G GASLINI INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PH; BINDING AFFINITIES; CYSTEINE RESIDUES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; CYTOSOLIC; DISSOCIATION CONSTANT; EFFECT OF PH; GENISTEIN; MULTIPLE EFFECT; NUCLEOTIDE-BINDING DOMAIN; SALT BRIDGES;

AMINO ACIDS; BINDING ENERGY; CHEMICAL ACTIVATION; DIMERS; DISSOCIATION; NUCLEOTIDES;

PH EFFECTS;

CYSTEINE; GENISTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ALKALINITY; AMINO ACID ANALYSIS; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL PH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DOSE RESPONSE; DRUG PROTEIN BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT;

AMINO ACIDS; ANIMALS; BINDING SITES; CELL MEMBRANE; CHLORIDE CHANNELS; CYSTEINE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOSOL; EPITHELIUM; GENISTEIN; HYDROGEN-ION CONCENTRATION; KINETICS; MUTATION; PROTEIN KINASE INHIBITORS; RATS;

EID: 78650631518     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.166850     Document Type: Article

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