Molecular mechanisms of chloroquine inhibition of heterologously expressed Kir6.2/SUR2A channels

Molecular Pharmacology

Volumn 82, Issue 5, 2012, Pages 803-813

  Ponce Balbuena, Daniela ^a   Rodríguez Menchaca, Aldo A ^b   López Izquierdo, Angélica ^a   Ferrer, Tania ^a   Kurata, Harley T ^c   Nichols, Colin G ^d   Sánchez Chapula, José A ^a  

^a UNIVERSIDAD DE COLIMA   (Mexico)

^b UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; SPERMINE; SULFONYLUREA RECEPTOR; SULFONYLUREA RECEPTOR 2A; UNCLASSIFIED DRUG;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DRUG MECHANISM; HEART DEPOLARIZATION; HEART REPOLARIZATION; HUMAN; HUMAN CELL; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

ANIMALS; ANTIMALARIALS; ATP-BINDING CASSETTE TRANSPORTERS; BINDING SITES; CHLOROQUINE; HEK293 CELLS; HUMANS; MICE; MUTATION; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, DRUG; SPERMINE; TRANSFECTION;

EID: 84867824387     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.079152     Document Type: Article

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