Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 11, 2001, Pages 6482-6487

  Zhou, Wei ^a   Arrabit, Christine ^a   Choe, Senyon ^a   Slesinger, Paul A ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BUPIVACAINE; GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCARINIC RECEPTOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POTASSIUM CHANNEL; POTASSIUM ION; PROTEIN SUBUNIT; VOLTAGE GATED CHANNEL FORMING PROTEIN;

ANIMAL CELL; ARTICLE; CHANNEL GATING; DRUG INHIBITION; DRUG MECHANISM; GIRK1 CHANNEL; GIRK2 CHANNEL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANESTHETICS, LOCAL; ANIMALS; BUPIVACAINE; ELECTROPHYSIOLOGY; ETHANOL; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, MUSCARINIC; XENOPUS LAEVIS;

ANIMALIA;

EID: 0035933202     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.111447798     Document Type: Article

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