Minocycline and fluorocitrate suppress spinal nociceptive signaling in intrathecal IL-1β-induced thermal hyperalgesic rats

GLIA

Volumn 60, Issue 12, 2012, Pages 2004-2017

  Sung, Chun Sung ^a,b   Cherng, Chen Hwan ^c   Wen, Zhi Hong ^d   Chang, Wen Kuei ^a,b   Huang, Shi Ying ^d   Lin, Shinn Long ^c   Chan, Kwok Hon ^a,b   Wong, Chih Shung ^e  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^d NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^e CATHAY GENERAL HOSPITAL   (Taiwan)

Author keywords

Astrocyte; INOS; Interleukin 1 ; MAPK; Microglia; Spinal cord

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CD11B ANTIGEN; FLUOROCITRIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCOPROTEIN P 15095; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG EFFECT; ENZYME PHOSPHORYLATION; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUMBAR SPINAL CORD; MALE; MICROGLIA; NERVE CELL; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD DORSAL HORN; THERMAL HYPERALGESIA; WESTERN BLOTTING;

ANIMALS; CITRATES; HYPERALGESIA; INJECTIONS, SPINAL; INTERLEUKIN-1BETA; MALE; MINOCYCLINE; PAIN; PAIN MEASUREMENT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SPINAL CORD;

EID: 84867656379     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22415     Document Type: Article

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