S632A3, a new glutarimide antibiotic, suppresses lipopolysaccharide-induced pro-inflammatory responses via inhibiting the activation of glycogen synthase kinase 3Β

Experimental Cell Research

Volumn 318, Issue 20, 2012, Pages 2592-2603

  Deng, Hongbin ^a   Zhang, Na ^a   Wang, Yan ^a   Chen, Jinjing ^a   Shen, Jiajia ^a   Wang, Zhen ^a   Xu, Rong ^a   Zhang, Jingpu ^a   Song, Danqing ^a   Li, Diandong ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

Glutarimide antibiotics; Glycogen synthsase kinase 3 ; Inflammation; Nuclear factor kappa B; P38

Indexed keywords

ANTIBIOTIC AGENT; APOPTOSIS SIGNAL REGULATING KINASE 1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLOOXYGENASE 2; GLUTARIMIDE DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3BETA; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN E2; S 632A3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; ENZYME ACTIVATION; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

STREPTOMYCES HYGROSCOPICUS;

EID: 84867633099     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2012.08.008     Document Type: Article

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