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Volumn 12, Issue , 2012, Pages

Tbx3 represses PTEN and is over-expressed in head and neck squamous cell carcinoma

Author keywords

Cancer; PTEN; Squamous cell carcinoma; Tbx3

Indexed keywords

GENOMIC DNA; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBX3; UNCLASSIFIED DRUG;

EID: 84867607610     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-12-481     Document Type: Article
Times cited : (44)

References (62)
  • 1
    • 0027282961 scopus 로고
    • The Brachyury gene encodes a novel DNA binding protein
    • 413588, 8344258
    • Kispert A, Herrmann BG. The Brachyury gene encodes a novel DNA binding protein. EMBO J 1993, 12(8):3211-3220. 413588, 8344258.
    • (1993) EMBO J , vol.12 , Issue.8 , pp. 3211-3220
    • Kispert, A.1    Herrmann, B.G.2
  • 2
    • 0031914530 scopus 로고    scopus 로고
    • The T-box gene family
    • 10.1002/(SICI)1521-1878(199801)20:1<9::AID-BIES4>3.0.CO;2-Q, 9504043
    • Papaioannou VE, Silver LM. The T-box gene family. Bioessays 1998, 20(1):9-19. 10.1002/(SICI)1521-1878(199801)20:1<9::AID-BIES4>3.0.CO;2-Q, 9504043.
    • (1998) Bioessays , vol.20 , Issue.1 , pp. 9-19
    • Papaioannou, V.E.1    Silver, L.M.2
  • 3
    • 0035115845 scopus 로고    scopus 로고
    • T-targets: clues to understanding the functions of T-box proteins
    • 10.1046/j.1440-169x.2001.00556.x, 11148447
    • Tada M, Smith JC. T-targets: clues to understanding the functions of T-box proteins. Dev Growth Differ 2001, 43(1):1-11. 10.1046/j.1440-169x.2001.00556.x, 11148447.
    • (2001) Dev Growth Differ , vol.43 , Issue.1 , pp. 1-11
    • Tada, M.1    Smith, J.C.2
  • 5
    • 0033621059 scopus 로고    scopus 로고
    • Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome
    • 10.1073/pnas.96.18.10212, 17868, 10468588
    • He M, Wen L, Campbell CE, Wu JY, Rao Y. Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome. Proc Natl Acad Sci USA 1999, 96(18):10212-10217. 10.1073/pnas.96.18.10212, 17868, 10468588.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.18 , pp. 10212-10217
    • He, M.1    Wen, L.2    Campbell, C.E.3    Wu, J.Y.4    Rao, Y.5
  • 6
    • 0037135545 scopus 로고    scopus 로고
    • The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator
    • 10.1074/jbc.M200403200, 12000749
    • Lingbeek ME, Jacobs JJ, van Lohuizen M. The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator. J Biol Chem 2002, 277(29):26120-26127. 10.1074/jbc.M200403200, 12000749.
    • (2002) J Biol Chem , vol.277 , Issue.29 , pp. 26120-26127
    • Lingbeek, M.E.1    Jacobs, J.J.2    van Lohuizen, M.3
  • 7
    • 0037797436 scopus 로고    scopus 로고
    • Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome
    • 10.1242/dev.00431, 12668638
    • Davenport TG, Jerome-Majewska LA, Papaioannou VE. Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome. Development 2003, 130(10):2263-2273. 10.1242/dev.00431, 12668638.
    • (2003) Development , vol.130 , Issue.10 , pp. 2263-2273
    • Davenport, T.G.1    Jerome-Majewska, L.A.2    Papaioannou, V.E.3
  • 9
    • 3442883903 scopus 로고    scopus 로고
    • TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines
    • 10.1158/0008-5472.CAN-04-0615, 15289316
    • Fan W, Huang X, Chen C, Gray J, Huang T. TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines. Cancer Res 2004, 64(15):5132-5139. 10.1158/0008-5472.CAN-04-0615, 15289316.
    • (2004) Cancer Res , vol.64 , Issue.15 , pp. 5132-5139
    • Fan, W.1    Huang, X.2    Chen, C.3    Gray, J.4    Huang, T.5
  • 12
    • 33847073865 scopus 로고    scopus 로고
    • Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer
    • 10.1158/0008-5472.CAN-06-2344, 17283120
    • Renard CA, Labalette C, Armengol C, Cougot D, Wei Y, Cairo S, Pineau P, Neuveut C, de Reynies A, Dejean A, et al. Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer. Cancer Res 2007, 67(3):901-910. 10.1158/0008-5472.CAN-06-2344, 17283120.
    • (2007) Cancer Res , vol.67 , Issue.3 , pp. 901-910
    • Renard, C.A.1    Labalette, C.2    Armengol, C.3    Cougot, D.4    Wei, Y.5    Cairo, S.6    Pineau, P.7    Neuveut, C.8    de Reynies, A.9    Dejean, A.10
  • 13
    • 54249133490 scopus 로고    scopus 로고
    • Tbx3 represses E-cadherin expression and enhances melanoma invasiveness
    • 10.1158/0008-5472.CAN-08-0301, 18829543
    • Rodriguez M, Aladowicz E, Lanfrancone L, Goding CR. Tbx3 represses E-cadherin expression and enhances melanoma invasiveness. Cancer Res 2008, 68(19):7872-7881. 10.1158/0008-5472.CAN-08-0301, 18829543.
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 7872-7881
    • Rodriguez, M.1    Aladowicz, E.2    Lanfrancone, L.3    Goding, C.R.4
  • 15
    • 78650732630 scopus 로고    scopus 로고
    • Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling
    • 10.1073/pnas.1007863107, 3003123, 21098263
    • Fillmore CM, Gupta PB, Rudnick JA, Caballero S, Keller PJ, Lander ES, Kuperwasser C. Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling. Proc Natl Acad Sci USA 2010, 107(50):21737-21742. 10.1073/pnas.1007863107, 3003123, 21098263.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.50 , pp. 21737-21742
    • Fillmore, C.M.1    Gupta, P.B.2    Rudnick, J.A.3    Caballero, S.4    Keller, P.J.5    Lander, E.S.6    Kuperwasser, C.7
  • 16
    • 4444363371 scopus 로고    scopus 로고
    • The role of Tbx2 and Tbx3 in mammary development and tumorigenesis
    • Rowley M, Grothey E, FJ C. The role of Tbx2 and Tbx3 in mammary development and tumorigenesis. J Mammary Gland Biol Neoplasia 2004, 9(2):109-118.
    • (2004) J Mammary Gland Biol Neoplasia , vol.9 , Issue.2 , pp. 109-118
    • Rowley, M.1    Grothey, E.2    FJ, C.3
  • 17
    • 0037198695 scopus 로고    scopus 로고
    • Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation
    • 10.1038/sj.onc.1205476, 12032820
    • Carlson H, Ota S, Song Y, Chen Y, Hurlin PJ. Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation. Oncogene 2002, 21(24):3827-3835. 10.1038/sj.onc.1205476, 12032820.
    • (2002) Oncogene , vol.21 , Issue.24 , pp. 3827-3835
    • Carlson, H.1    Ota, S.2    Song, Y.3    Chen, Y.4    Hurlin, P.J.5
  • 18
    • 0037155231 scopus 로고    scopus 로고
    • TBX-3, the gene mutated in ulnar-mammary syndrome, is a negative regulator of p19ARF and inhibits senescence
    • 10.1074/jbc.M110492200, 11748239
    • Brummelkamp TR, Kortlever RM, Lingbeek M, Trettel F, MacDonald ME, van Lohuizen M, Bernards R. TBX-3, the gene mutated in ulnar-mammary syndrome, is a negative regulator of p19ARF and inhibits senescence. J Biol Chem 2002, 277(8):6567-6572. 10.1074/jbc.M110492200, 11748239.
    • (2002) J Biol Chem , vol.277 , Issue.8 , pp. 6567-6572
    • Brummelkamp, T.R.1    Kortlever, R.M.2    Lingbeek, M.3    Trettel, F.4    MacDonald, M.E.5    van Lohuizen, M.6    Bernards, R.7
  • 19
    • 0035504693 scopus 로고    scopus 로고
    • A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome
    • 10.1093/hmg/10.21.2403, 11689487
    • Carlson H, Ota S, Campbell CE, Hurlin PJ. A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome. Hum Mol Genet 2001, 10(21):2403-2413. 10.1093/hmg/10.21.2403, 11689487.
    • (2001) Hum Mol Genet , vol.10 , Issue.21 , pp. 2403-2413
    • Carlson, H.1    Ota, S.2    Campbell, C.E.3    Hurlin, P.J.4
  • 21
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world
    • 10.1200/JCO.2005.05.2308, 16682732
    • Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006, 24(14):2137-2150. 10.1200/JCO.2005.05.2308, 16682732.
    • (2006) J Clin Oncol , vol.24 , Issue.14 , pp. 2137-2150
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 23
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • 10.1056/NEJMra023075, 14627790
    • Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003, 349(21):2042-2054. 10.1056/NEJMra023075, 14627790.
    • (2003) N Engl J Med , vol.349 , Issue.21 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 24
    • 0037142615 scopus 로고    scopus 로고
    • Patterns of gene promoter methylation in squamous cell cancer of the head and neck
    • 10.1038/sj.onc.1205528, 12082610
    • Hasegawa M, Nelson HH, Peters E, Ringstrom E, Posner M, Kelsey KT. Patterns of gene promoter methylation in squamous cell cancer of the head and neck. Oncogene 2002, 21(27):4231-4236. 10.1038/sj.onc.1205528, 12082610.
    • (2002) Oncogene , vol.21 , Issue.27 , pp. 4231-4236
    • Hasegawa, M.1    Nelson, H.H.2    Peters, E.3    Ringstrom, E.4    Posner, M.5    Kelsey, K.T.6
  • 25
    • 0028960673 scopus 로고
    • Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck
    • 10.1056/NEJM199503163321104, 7854378
    • Brennan JA, Boyle JO, Koch WM, Goodman SN, Hruban RH, Eby YJ, Couch MJ, Forastiere AA, Sidransky D. Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck. N Engl J Med 1995, 332(11):712-717. 10.1056/NEJM199503163321104, 7854378.
    • (1995) N Engl J Med , vol.332 , Issue.11 , pp. 712-717
    • Brennan, J.A.1    Boyle, J.O.2    Koch, W.M.3    Goodman, S.N.4    Hruban, R.H.5    Eby, Y.J.6    Couch, M.J.7    Forastiere, A.A.8    Sidransky, D.9
  • 26
    • 0036162726 scopus 로고    scopus 로고
    • Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10
    • 10.1016/S0165-4608(01)00509-X, 11801303
    • Poetsch M, Lorenz G, Kleist B. Detection of new PTEN/MMAC1 mutations in head and neck squamous cell carcinomas with loss of chromosome 10. Cancer Genet Cytogenet 2002, 132(1):20-24. 10.1016/S0165-4608(01)00509-X, 11801303.
    • (2002) Cancer Genet Cytogenet , vol.132 , Issue.1 , pp. 20-24
    • Poetsch, M.1    Lorenz, G.2    Kleist, B.3
  • 29
    • 0346645692 scopus 로고    scopus 로고
    • The role of epidermal growth factor receptor in head and neck squamous cell carcinoma
    • 10.1007/s11912-003-0101-z, 12583831
    • Pomerantz RG, Grandis JR. The role of epidermal growth factor receptor in head and neck squamous cell carcinoma. Curr Oncol Rep 2003, 5(2):140-146. 10.1007/s11912-003-0101-z, 12583831.
    • (2003) Curr Oncol Rep , vol.5 , Issue.2 , pp. 140-146
    • Pomerantz, R.G.1    Grandis, J.R.2
  • 31
    • 33746257209 scopus 로고    scopus 로고
    • The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
    • 10.1038/nrg1879, 16847462
    • Engelman JA, Luo J, Cantley LC. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat Rev Genet 2006, 7(8):606-619. 10.1038/nrg1879, 16847462.
    • (2006) Nat Rev Genet , vol.7 , Issue.8 , pp. 606-619
    • Engelman, J.A.1    Luo, J.2    Cantley, L.C.3
  • 33
    • 54449101189 scopus 로고    scopus 로고
    • Akt pathway as a target for therapeutic intervention in HNSCC
    • Moral M, Paramio JM. Akt pathway as a target for therapeutic intervention in HNSCC. Histol Histopathol 2008, 23(10):1269-1278.
    • (2008) Histol Histopathol , vol.23 , Issue.10 , pp. 1269-1278
    • Moral, M.1    Paramio, J.M.2
  • 34
    • 0031439404 scopus 로고    scopus 로고
    • The national cancer data base report on recent hospital cancer program progress toward complete american joint committee on cancer/TNM staging
    • 10.1002/(SICI)1097-0142(19971215)80:12<2305::AID-CNCR12>3.0.CO;2-Y, 9404708
    • Fleming ID, Phillips JL, Menck HR, Murphy GP, Winchester DP. The national cancer data base report on recent hospital cancer program progress toward complete american joint committee on cancer/TNM staging. Cancer 1997, 80(12):2305-2310. 10.1002/(SICI)1097-0142(19971215)80:12<2305::AID-CNCR12>3.0.CO;2-Y, 9404708.
    • (1997) Cancer , vol.80 , Issue.12 , pp. 2305-2310
    • Fleming, I.D.1    Phillips, J.L.2    Menck, H.R.3    Murphy, G.P.4    Winchester, D.P.5
  • 35
    • 0036291334 scopus 로고    scopus 로고
    • Promoter analysis of tumor suppressor gene PTEN: identification of minimum promoter region
    • 10.1006/bbrc.2002.6662, 11906179
    • Sheng X, Koul D, Liu JL, Liu TJ, Yung WK. Promoter analysis of tumor suppressor gene PTEN: identification of minimum promoter region. Biochem Biophys Res Commun 2002, 292(2):422-426. 10.1006/bbrc.2002.6662, 11906179.
    • (2002) Biochem Biophys Res Commun , vol.292 , Issue.2 , pp. 422-426
    • Sheng, X.1    Koul, D.2    Liu, J.L.3    Liu, T.J.4    Yung, W.K.5
  • 36
    • 34447335844 scopus 로고    scopus 로고
    • Comparative genomic and functional analyses reveal a novel cis-acting PTEN regulatory element as a highly conserved functional E-box motif deleted in Cowden syndrome
    • 10.1093/hmg/ddm053, 17341483
    • Pezzolesi MG, Zbuk KM, Waite KA, Eng C. Comparative genomic and functional analyses reveal a novel cis-acting PTEN regulatory element as a highly conserved functional E-box motif deleted in Cowden syndrome. Hum Mol Genet 2007, 16(9):1058-1071. 10.1093/hmg/ddm053, 17341483.
    • (2007) Hum Mol Genet , vol.16 , Issue.9 , pp. 1058-1071
    • Pezzolesi, M.G.1    Zbuk, K.M.2    Waite, K.A.3    Eng, C.4
  • 37
    • 0035199914 scopus 로고    scopus 로고
    • The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
    • 10.1038/ncb1201-1124, 11781575
    • Virolle T, Adamson ED, Baron V, Birle D, Mercola D, Mustelin T, de Belle I. The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling. Nat Cell Biol 2001, 3(12):1124-1128. 10.1038/ncb1201-1124, 11781575.
    • (2001) Nat Cell Biol , vol.3 , Issue.12 , pp. 1124-1128
    • Virolle, T.1    Adamson, E.D.2    Baron, V.3    Birle, D.4    Mercola, D.5    Mustelin, T.6    de Belle, I.7
  • 38
    • 33846621883 scopus 로고    scopus 로고
    • CBF-1 (RBP-J kappa) binds to the PTEN promoter and regulates PTEN gene expression
    • 10.4161/cc.6.1.3648, 17245125
    • Whelan JT, Forbes SL, Bertrand FE. CBF-1 (RBP-J kappa) binds to the PTEN promoter and regulates PTEN gene expression. Cell Cycle 2007, 6(1):80-84. 10.4161/cc.6.1.3648, 17245125.
    • (2007) Cell Cycle , vol.6 , Issue.1 , pp. 80-84
    • Whelan, J.T.1    Forbes, S.L.2    Bertrand, F.E.3
  • 40
    • 84855900675 scopus 로고    scopus 로고
    • The biology of head and neck cancer stem cells
    • 10.1016/j.oraloncology.2011.10.004, 22070916
    • Zhang Z, Filho MS, Nor JE. The biology of head and neck cancer stem cells. Oral Oncol 2012, 48(1):1-9. 10.1016/j.oraloncology.2011.10.004, 22070916.
    • (2012) Oral Oncol , vol.48 , Issue.1 , pp. 1-9
    • Zhang, Z.1    Filho, M.S.2    Nor, J.E.3
  • 41
    • 79551485331 scopus 로고    scopus 로고
    • PMA-induced up-regulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration
    • 10.1042/BJ20100886, 20942798
    • Mowla S, Pinnock R, Leaner VD, Goding CR, Prince S. PMA-induced up-regulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration. Biochem J 2011, 433(1):145-153. 10.1042/BJ20100886, 20942798.
    • (2011) Biochem J , vol.433 , Issue.1 , pp. 145-153
    • Mowla, S.1    Pinnock, R.2    Leaner, V.D.3    Goding, C.R.4    Prince, S.5
  • 43
    • 67349204371 scopus 로고    scopus 로고
    • Targeting EGFR resistance networks in head and neck cancer
    • 10.1016/j.cellsig.2009.02.021, 2770888, 19258037
    • Ratushny V, Astsaturov I, Burtness BA, Golemis EA, Silverman JS. Targeting EGFR resistance networks in head and neck cancer. Cell Signal 2009, 21(8):1255-1268. 10.1016/j.cellsig.2009.02.021, 2770888, 19258037.
    • (2009) Cell Signal , vol.21 , Issue.8 , pp. 1255-1268
    • Ratushny, V.1    Astsaturov, I.2    Burtness, B.A.3    Golemis, E.A.4    Silverman, J.S.5
  • 44
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • 10.1126/science.1203543, 21436443
    • Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science 2011, 331(6024):1559-1564. 10.1126/science.1203543, 21436443.
    • (2011) Science , vol.331 , Issue.6024 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 45
    • 84856085546 scopus 로고    scopus 로고
    • Transcriptional profiling identifies upregulated genes following induction of epithelial-mesenchymal transition in squamous carcinoma cells
    • 10.1016/j.yexcr.2011.11.011, 22154512
    • Humtsoe JO, Koya E, Pham E, Aramoto T, Zuo J, Ishikawa T, Kramer RH. Transcriptional profiling identifies upregulated genes following induction of epithelial-mesenchymal transition in squamous carcinoma cells. Exp Cell Res 2012, 318(4):379-390. 10.1016/j.yexcr.2011.11.011, 22154512.
    • (2012) Exp Cell Res , vol.318 , Issue.4 , pp. 379-390
    • Humtsoe, J.O.1    Koya, E.2    Pham, E.3    Aramoto, T.4    Zuo, J.5    Ishikawa, T.6    Kramer, R.H.7
  • 46
    • 0042316755 scopus 로고    scopus 로고
    • PTEN: one gene, many syndromes
    • 10.1002/humu.10257, 12938083
    • Eng C. PTEN: one gene, many syndromes. Hum Mutat 2003, 22(3):183-198. 10.1002/humu.10257, 12938083.
    • (2003) Hum Mutat , vol.22 , Issue.3 , pp. 183-198
    • Eng, C.1
  • 47
    • 21644437763 scopus 로고    scopus 로고
    • Characterization of chromosome 3q and 12q amplicons in nasopharyngeal carcinoma cell lines
    • Or YY, Hui AB, Tam KY, Huang DP, Lo KW. Characterization of chromosome 3q and 12q amplicons in nasopharyngeal carcinoma cell lines. Int J Oncol 2005, 26(1):49-56.
    • (2005) Int J Oncol , vol.26 , Issue.1 , pp. 49-56
    • Or, Y.Y.1    Hui, A.B.2    Tam, K.Y.3    Huang, D.P.4    Lo, K.W.5
  • 48
    • 33646703327 scopus 로고    scopus 로고
    • A novel mutation of STK11/LKB1 gene leads to the loss of cell growth inhibition in head and neck squamous cell carcinoma
    • 10.1038/sj.onc.1209325, 1459486, 16407837
    • Qiu W, Schonleben F, Thaker HM, Goggins M, Su GH. A novel mutation of STK11/LKB1 gene leads to the loss of cell growth inhibition in head and neck squamous cell carcinoma. Oncogene 2006, 25(20):2937-2942. 10.1038/sj.onc.1209325, 1459486, 16407837.
    • (2006) Oncogene , vol.25 , Issue.20 , pp. 2937-2942
    • Qiu, W.1    Schonleben, F.2    Thaker, H.M.3    Goggins, M.4    Su, G.H.5
  • 49
    • 0036841057 scopus 로고    scopus 로고
    • Genomic gain of PIK3CA and increased expression of p110alpha are associated with progression of dysplasia into invasive squamous cell carcinoma
    • 10.1002/path.1207, 12375266
    • Woenckhaus J, Steger K, Werner E, Fenic I, Gamerdinger U, Dreyer T, Stahl U. Genomic gain of PIK3CA and increased expression of p110alpha are associated with progression of dysplasia into invasive squamous cell carcinoma. J Pathol 2002, 198(3):335-342. 10.1002/path.1207, 12375266.
    • (2002) J Pathol , vol.198 , Issue.3 , pp. 335-342
    • Woenckhaus, J.1    Steger, K.2    Werner, E.3    Fenic, I.4    Gamerdinger, U.5    Dreyer, T.6    Stahl, U.7
  • 51
    • 35348929259 scopus 로고    scopus 로고
    • Expression of PTEN protein in patients with laryngeal squamous cell carcinoma
    • 10.1016/j.anl.2007.03.014, 17475427
    • Guney K, Ozbilim G, Derin AT, Cetin S. Expression of PTEN protein in patients with laryngeal squamous cell carcinoma. Auris Nasus Larynx 2007, 34(4):481-486. 10.1016/j.anl.2007.03.014, 17475427.
    • (2007) Auris Nasus Larynx , vol.34 , Issue.4 , pp. 481-486
    • Guney, K.1    Ozbilim, G.2    Derin, A.T.3    Cetin, S.4
  • 54
    • 0039706410 scopus 로고    scopus 로고
    • Crystallographic structure of the T domain-DNA complex of the brachyury transcription factor
    • 10.1038/39929, 9349824
    • Muller CW, Herrmann BG. Crystallographic structure of the T domain-DNA complex of the brachyury transcription factor. Nature 1997, 389(6653):884-888. 10.1038/39929, 9349824.
    • (1997) Nature , vol.389 , Issue.6653 , pp. 884-888
    • Muller, C.W.1    Herrmann, B.G.2
  • 55
    • 0031812415 scopus 로고    scopus 로고
    • Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter
    • 109095, 9710594
    • Carreira S, Dexter TJ, Yavuzer U, Easty DJ, Goding CR. Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter. Mol Cell Biol 1998, 18(9):5099-5108. 109095, 9710594.
    • (1998) Mol Cell Biol , vol.18 , Issue.9 , pp. 5099-5108
    • Carreira, S.1    Dexter, T.J.2    Yavuzer, U.3    Easty, D.J.4    Goding, C.R.5
  • 57
    • 0034931034 scopus 로고    scopus 로고
    • Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
    • 10.1038/90123, 11431700
    • Hiroi Y, Kudoh S, Monzen K, Ikeda Y, Yazaki Y, Nagai R, Komuro I. Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat Genet 2001, 28(3):276-280. 10.1038/90123, 11431700.
    • (2001) Nat Genet , vol.28 , Issue.3 , pp. 276-280
    • Hiroi, Y.1    Kudoh, S.2    Monzen, K.3    Ikeda, Y.4    Yazaki, Y.5    Nagai, R.6    Komuro, I.7
  • 58
    • 0035937414 scopus 로고    scopus 로고
    • A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins
    • 10.1016/S0092-8674(01)00282-3, 11290323
    • Lamolet B, Pulichino AM, Lamonerie T, Gauthier Y, Brue T, Enjalbert A, Drouin J. A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins. Cell 2001, 104(6):849-859. 10.1016/S0092-8674(01)00282-3, 11290323.
    • (2001) Cell , vol.104 , Issue.6 , pp. 849-859
    • Lamolet, B.1    Pulichino, A.M.2    Lamonerie, T.3    Gauthier, Y.4    Brue, T.5    Enjalbert, A.6    Drouin, J.7
  • 59
    • 3042830441 scopus 로고    scopus 로고
    • Regulation of Bcl-2 proteins during anoikis and amorphosis
    • Martin SS, Vuori K. Regulation of Bcl-2 proteins during anoikis and amorphosis. Biochim Biophys Acta 2004, 1692(2-3):145-157.
    • (2004) Biochim Biophys Acta , vol.1692 , Issue.2-3 , pp. 145-157
    • Martin, S.S.1    Vuori, K.2
  • 61
    • 0034921007 scopus 로고    scopus 로고
    • Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis
    • Yamada KM, Araki M. Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis. J Cell Sci 2001, 114(Pt 13):2375-2382.
    • (2001) J Cell Sci , vol.114 , Issue.PART 13 , pp. 2375-2382
    • Yamada, K.M.1    Araki, M.2
  • 62
    • 70350539589 scopus 로고    scopus 로고
    • Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells
    • 10.1158/0008-5472.CAN-09-1067, 2783190, 19843859
    • Vitolo MI, Weiss MB, Szmacinski M, Tahir K, Waldman T, Park BH, Martin SS, Weber DJ, Bachman KE. Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells. Cancer Res 2009, 69(21):8275-8283. 10.1158/0008-5472.CAN-09-1067, 2783190, 19843859.
    • (2009) Cancer Res , vol.69 , Issue.21 , pp. 8275-8283
    • Vitolo, M.I.1    Weiss, M.B.2    Szmacinski, M.3    Tahir, K.4    Waldman, T.5    Park, B.H.6    Martin, S.S.7    Weber, D.J.8    Bachman, K.E.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.