A novel mutation of STK11/LKB1 gene leads to the loss of cell growth inhibition in head and neck squamous cell carcinoma

Oncogene

Volumn 25, Issue 20, 2006, Pages 2937-2942

  Qiu, W ^a   Schonleben F ^a   Thaker, H M ^a   Goggins, M ^b   Su, G H ^a  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Genetic mutation; HNSCC; LKB1; PJS; STK11; Tumor suppressor gene

Indexed keywords

PROTEIN KINASE LKB1;

AMINO ACID SUBSTITUTION; ARTICLE; CANCER GROWTH; CHROMOSOME 19P; CONTROLLED STUDY; EXON; EXPRESSION VECTOR; GENE; GENE MUTATION; GENETIC TRANSFECTION; HEAD AND NECK CARCINOMA; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; MISSENSE MUTATION; MUTATION RATE; NUCLEOTIDE SEQUENCE; PEUTZ JEGHERS SYNDROME; POINT MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; SQUAMOUS CELL CARCINOMA; STK11 GENE; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; WILD TYPE;

AMINO ACID SUBSTITUTION; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; DNA MUTATIONAL ANALYSIS; EXONS; GERM-LINE MUTATION; HEAD AND NECK NEOPLASMS; HUMANS; INTRONS; LOSS OF HETEROZYGOSITY; MUTATION, MISSENSE; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROTEIN-SERINE-THREONINE KINASES;

EID: 33646703327     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209325     Document Type: Article

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