-
1
-
-
41049114747
-
How to make a melanoma: What do we know of the primary clonal events? Pigment Cell
-
Bennett DC. How to make a melanoma: what do we know of the primary clonal events? Pigment Cell Melanoma Res 2008;21:27-38.
-
(2008)
Melanoma Res
, vol.21
, pp. 27-38
-
-
Bennett, D.C.1
-
2
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002;417:949-54.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
3
-
-
23244447037
-
BRAFE600-associated senescence-like cell cycle arrest of human naevi
-
Michaloglou C, Vredeveld LC, Soengas MS, et al. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 2005;436:720-4.
-
(2005)
Nature
, vol.436
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.2
Soengas, M.S.3
-
4
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997;88:593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
5
-
-
33747192833
-
Cellular senescence in naevi and immortalisation in melanoma: A role for p16?
-
Gray-Schopfer VC, Cheong SC, Chong H, et al. Cellular senescence in naevi and immortalisation in melanoma: a role for p16? Br J Cancer 2006;95:496-505.
-
(2006)
Br J Cancer
, vol.95
, pp. 496-505
-
-
Gray-Schopfer, V.C.1
Cheong, S.C.2
Chong, H.3
-
6
-
-
0038819652
-
The INK4a/ARF locus and melanoma
-
Sharpless E, Chin L. The INK4a/ARF locus and melanoma. Oncogene 2003;22:3092-8.
-
(2003)
Oncogene
, vol.22
, pp. 3092-3098
-
-
Sharpless, E.1
Chin, L.2
-
7
-
-
0037941546
-
p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: Possible implications for melanoma progression
-
Sviderskaya EV, Gray-Schopfer VC, Hill SP, et al. p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: possible implications for melanoma progression. J Natl Cancer Inst 2003;95:723-32.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 723-732
-
-
Sviderskaya, E.V.1
Gray-Schopfer, V.C.2
Hill, S.P.3
-
8
-
-
19544362066
-
Adhesion, migration and communication in melanocytes and melanoma
-
Haass NK, Smalley KS, Li L, Herlyn M. Adhesion, migration and communication in melanocytes and melanoma. Pigment Cell Res 2005;18:150-9.
-
(2005)
Pigment Cell Res
, vol.18
, pp. 150-159
-
-
Haass, N.K.1
Smalley, K.S.2
Li, L.3
Herlyn, M.4
-
10
-
-
0031812415
-
Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter
-
Carreira S, Dexter TJ, Yavuzer U, Easty DJ, Goding CR. Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter. Mol Cell Biol 1998;18:5099-108.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5099-5108
-
-
Carreira, S.1
Dexter, T.J.2
Yavuzer, U.3
Easty, D.J.4
Goding, C.R.5
-
11
-
-
0033764030
-
Senescence bypass screen identifies Tbx2, which represses cdkn2a (p19ARF) and is amplified in a subset of human breast cancers
-
Jacobs JJ, Keblusek P, Robanus-Maandag E, et al. Senescence bypass screen identifies Tbx2, which represses cdkn2a (p19ARF) and is amplified in a subset of human breast cancers. Nat Genet 2000;26:291-9.
-
(2000)
Nat Genet
, vol.26
, pp. 291-299
-
-
Jacobs, J.J.1
Keblusek, P.2
Robanus-Maandag, E.3
-
12
-
-
0037093383
-
Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: Implications for cardiac chamber formation
-
Habets PE, Moorman AF, Clout DE, et al. Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation. Genes Dev 2002;16:1234-46.
-
(2002)
Genes Dev
, vol.16
, pp. 1234-1246
-
-
Habets, P.E.1
Moorman, A.F.2
Clout, D.E.3
-
13
-
-
0037135545
-
The T-box repressors TBX2 and TBX3 specifically regulate the tumour suppressor gene p14ARF via a variant T-site in the initiator
-
Lingbeek ME, Jacobs JJ, Van Lohuizen M. The T-box repressors TBX2 and TBX3 specifically regulate the tumour suppressor gene p14ARF via a variant T-site in the initiator. J Biol Chem 2002;277:26120-7.
-
(2002)
J Biol Chem
, vol.277
, pp. 26120-26127
-
-
Lingbeek, M.E.1
Jacobs, J.J.2
Van Lohuizen, M.3
-
14
-
-
1642396456
-
Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor
-
Prince S, Carreira S, Vance KW, Abrahams A, Goding CR. Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor. Cancer Res 2004;64:1669-74.
-
(2004)
Cancer Res
, vol.64
, pp. 1669-1674
-
-
Prince, S.1
Carreira, S.2
Vance, K.W.3
Abrahams, A.4
Goding, C.R.5
-
15
-
-
0036120604
-
Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome
-
Coll M, Seidman JG, Muller CW. Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome. Structure (Camb) 2002;10:343-56.
-
(2002)
Structure (Camb)
, vol.10
, pp. 343-356
-
-
Coll, M.1
Seidman, J.G.2
Muller, C.W.3
-
16
-
-
0037155231
-
TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence
-
Brummelkamp TR, Kortlever RM, Lingbeek M, et al. TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence. J Biol Chem 2002;277:6567-72.
-
(2002)
J Biol Chem
, vol.277
, pp. 6567-6572
-
-
Brummelkamp, T.R.1
Kortlever, R.M.2
Lingbeek, M.3
-
17
-
-
43549088089
-
TBX3 and its splice variant TBX3 + exon 2a are functionally similar
-
Hoogaars WM, Barnett P, Rodriguez M, et al. TBX3 and its splice variant TBX3 + exon 2a are functionally similar. Pigment Cell Melanoma Res 2008;21:379-87.
-
(2008)
Pigment Cell Melanoma Res
, vol.21
, pp. 379-387
-
-
Hoogaars, W.M.1
Barnett, P.2
Rodriguez, M.3
-
18
-
-
16844387097
-
Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas
-
Vance KW, Carreira S, Brosch G, Goding CR. Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas. Cancer Res 2005;65:2260-8.
-
(2005)
Cancer Res
, vol.65
, pp. 2260-2268
-
-
Vance, K.W.1
Carreira, S.2
Brosch, G.3
Goding, C.R.4
-
19
-
-
34447515273
-
Genomic profiling of malignant melanoma using tiling-resolution array CGH
-
Jonsson G, Dahl C, Staaf J, et al. Genomic profiling of malignant melanoma using tiling-resolution array CGH. Oncogene 2007;26:4738-48.
-
(2007)
Oncogene
, vol.26
, pp. 4738-4748
-
-
Jonsson, G.1
Dahl, C.2
Staaf, J.3
-
20
-
-
0036883715
-
Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer
-
Mahlamaki EH, Barlund M, Tanner M, et al. Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer. Genes Chromosomes Cancer 2002;35:353-8.
-
(2002)
Genes Chromosomes Cancer
, vol.35
, pp. 353-358
-
-
Mahlamaki, E.H.1
Barlund, M.2
Tanner, M.3
-
21
-
-
0036645397
-
Tbx2 is preferentially amplified in BRCA1- and BRCA2-related breast tumours
-
Sinclair CS, Adem C, Naderi A, et al. Tbx2 is preferentially amplified in BRCA1- and BRCA2-related breast tumours. Cancer Res 2002;62:3587-91.
-
(2002)
Cancer Res
, vol.62
, pp. 3587-3591
-
-
Sinclair, C.S.1
Adem, C.2
Naderi, A.3
-
22
-
-
3442894137
-
Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas
-
Hoek K, Rimm DL, Williams KR, et al. Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res 2004;64:5270-82.
-
(2004)
Cancer Res
, vol.64
, pp. 5270-5282
-
-
Hoek, K.1
Rimm, D.L.2
Williams, K.R.3
-
23
-
-
28544450672
-
Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients
-
Lomnytska M, Dubrovska A, Hellman U, Volodko N, Souchelnytskyi S. Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients. Int J Cancer 2006;118:412-21.
-
(2006)
Int J Cancer
, vol.118
, pp. 412-421
-
-
Lomnytska, M.1
Dubrovska, A.2
Hellman, U.3
Volodko, N.4
Souchelnytskyi, S.5
-
24
-
-
3442883903
-
TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines
-
Fan W, Huang X, Chen C, Gray J, Huang, T. TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines. Cancer Res 2004;64:5132-9.
-
(2004)
Cancer Res
, vol.64
, pp. 5132-5139
-
-
Fan, W.1
Huang, X.2
Chen, C.3
Gray, J.4
Huang, T.5
-
25
-
-
33750443923
-
Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer
-
Lyng H, Brovig RS, Svendsrud DH, et al. Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer. BMC Genomics 2006;7:268-73.
-
(2006)
BMC Genomics
, vol.7
, pp. 268-273
-
-
Lyng, H.1
Brovig, R.S.2
Svendsrud, D.H.3
-
26
-
-
38849139136
-
TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases
-
Yarosh W, Barrientos T, Esmailpour T, et al. TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases. Cancer Res 2008;68:693-9.
-
(2008)
Cancer Res
, vol.68
, pp. 693-699
-
-
Yarosh, W.1
Barrientos, T.2
Esmailpour, T.3
-
27
-
-
0034698141
-
The gene encoding the T-box transcription factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes
-
Carreira S, Liu B, Goding CR. The gene encoding the T-box transcription factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes. J Biol Chem 2000;275:21920-7.
-
(2000)
J Biol Chem
, vol.275
, pp. 21920-21927
-
-
Carreira, S.1
Liu, B.2
Goding, C.R.3
-
28
-
-
13944273767
-
Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression
-
Carreira S, Goodall J, Aksan I, et al. Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression. Nature 2005;433:764-9.
-
(2005)
Nature
, vol.433
, pp. 764-769
-
-
Carreira, S.1
Goodall, J.2
Aksan, I.3
-
29
-
-
34248630805
-
Confirmation of a BRAF mutation-associated gene expression signature in melanoma
-
Johansson P, Pavey S, Hayward N. Confirmation of a BRAF mutation-associated gene expression signature in melanoma. Pigment Cell Res 2007;20:216-21.
-
(2007)
Pigment Cell Res
, vol.20
, pp. 216-221
-
-
Johansson, P.1
Pavey, S.2
Hayward, N.3
-
30
-
-
0033789680
-
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
-
Batlle E, Sancho E, Franci C, et al. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol 2000;2:84-9.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 84-89
-
-
Batlle, E.1
Sancho, E.2
Franci, C.3
-
31
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano A, Perez-Moreno MA, Rodrigo I, et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2000;2:76-83.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 76-83
-
-
Cano, A.1
Perez-Moreno, M.A.2
Rodrigo, I.3
-
32
-
-
0034931034
-
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
-
Hiroi Y, Kudoh S, Monzen K, et al. Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat Genet 2001;28:276-80.
-
(2001)
Nat Genet
, vol.28
, pp. 276-280
-
-
Hiroi, Y.1
Kudoh, S.2
Monzen, K.3
-
33
-
-
4043139388
-
Tbx5 and Tbx4 transcription factors interact with a new chicken PDZ-LIM protein in limb and heart development
-
Krause A, Zacharias W, Camarata T, et al. Tbx5 and Tbx4 transcription factors interact with a new chicken PDZ-LIM protein in limb and heart development. Dev Biol 2004;273:106-20.
-
(2004)
Dev Biol
, vol.273
, pp. 106-120
-
-
Krause, A.1
Zacharias, W.2
Camarata, T.3
-
34
-
-
0035937414
-
A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins
-
Lamolet B, Pulichino AM, Lamonerie T, et al. A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins. Cell 2001;104:849-59.
-
(2001)
Cell
, vol.104
, pp. 849-859
-
-
Lamolet, B.1
Pulichino, A.M.2
Lamonerie, T.3
-
35
-
-
16244385939
-
Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1
-
Messenger NJ, Kabitschke C, Andrews R, et al. Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1. Dev Cell 2005;8:599-610.
-
(2005)
Dev Cell
, vol.8
, pp. 599-610
-
-
Messenger, N.J.1
Kabitschke, C.2
Andrews, R.3
-
36
-
-
29144512222
-
A WW domain protein TAZ is a critical coactivator for Tbx5, a transcription factor implicated in Holt-Oram syndrome
-
Murakami M, Nakagawa M, Olson EN, Nakagawa O. A WW domain protein TAZ is a critical coactivator for Tbx5, a transcription factor implicated in Holt-Oram syndrome. Proc Natl Acad Sci U S A 2005;102:18034-9.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18034-18039
-
-
Murakami, M.1
Nakagawa, M.2
Olson, E.N.3
Nakagawa, O.4
-
37
-
-
0141615095
-
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart
-
Stennard FA, Costa MW, Elliott DA, et al. Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. Dev Biol 2003;262:206-24.
-
(2003)
Dev Biol
, vol.262
, pp. 206-224
-
-
Stennard, F.A.1
Costa, M.W.2
Elliott, D.A.3
-
38
-
-
34447303597
-
T-box factors: Targeting to chromatin and interaction with the histone H3 N-terminal tail
-
Demay F, Bilican B, Rodriguez M, et al. T-box factors: targeting to chromatin and interaction with the histone H3 N-terminal tail. Pigment Cell Res 2007;20:279-87.
-
(2007)
Pigment Cell Res
, vol.20
, pp. 279-287
-
-
Demay, F.1
Bilican, B.2
Rodriguez, M.3
-
39
-
-
0027282961
-
The Brachyury gene encodes a novel DNA-binding protein
-
Kispert A, Herrmann BG. The Brachyury gene encodes a novel DNA-binding protein. EMBO J 1993;12:3211-20.
-
(1993)
EMBO J
, vol.12
, pp. 3211-3220
-
-
Kispert, A.1
Herrmann, B.G.2
-
40
-
-
0039706410
-
Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor
-
Müller CW, Herrmann BG. Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor. Nature 1997;389:884-9.
-
(1997)
Nature
, vol.389
, pp. 884-889
-
-
Müller, C.W.1
Herrmann, B.G.2
-
41
-
-
4043115638
-
Deletion in p16INK4a and loss of p16 expression in human skin primary and metastatic melanoma cells
-
Zhang H, Rosdahl I. Deletion in p16INK4a and loss of p16 expression in human skin primary and metastatic melanoma cells. Int J Oncol 2004;24:331-5.
-
(2004)
Int J Oncol
, vol.24
, pp. 331-335
-
-
Zhang, H.1
Rosdahl, I.2
-
42
-
-
33745281202
-
Cell cycle regulation of the T-box transcription factor Tbx2
-
Bilican B, Goding CR. Cell cycle regulation of the T-box transcription factor Tbx2. Exp Cell Res 2006;312:2358-66.
-
(2006)
Exp Cell Res
, vol.312
, pp. 2358-2366
-
-
Bilican, B.1
Goding, C.R.2
-
43
-
-
0041971124
-
Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois
-
Naiche LA, Papaioannou VE. Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois. Development 2003;130:2681-93.
-
(2003)
Development
, vol.130
, pp. 2681-2693
-
-
Naiche, L.A.1
Papaioannou, V.E.2
-
44
-
-
0033614409
-
The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity
-
Rodriguez-Esteban C, Tsukui T, Yonei S, Magallon J, Tamura K, Izpisua Belmonte JC. The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity. Nature 1999;398:814-8.
-
(1999)
Nature
, vol.398
, pp. 814-818
-
-
Rodriguez-Esteban, C.1
Tsukui, T.2
Yonei, S.3
Magallon, J.4
Tamura, K.5
Izpisua Belmonte, J.C.6
-
45
-
-
21044446280
-
Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation
-
Stennard FA, Costa MW, Lai D, et al. Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development 2005;132:2451-62.
-
(2005)
Development
, vol.132
, pp. 2451-2462
-
-
Stennard, F.A.1
Costa, M.W.2
Lai, D.3
-
46
-
-
0033614374
-
Tbx5 and Tbx4 genes determine the wing/leg identity of limb buds
-
Takeuchi JK, Koshiba-Takeuchi K, Matsumoto K, et al. Tbx5 and Tbx4 genes determine the wing/leg identity of limb buds. Nature 1999;398:810-4.
-
(1999)
Nature
, vol.398
, pp. 810-814
-
-
Takeuchi, J.K.1
Koshiba-Takeuchi, K.2
Matsumoto, K.3
|