Ursolic acid induces ER stress response to activate ASK1-JNK signaling and induce apoptosis in human bladder cancer T24 cells

Cellular Signalling

Volumn 25, Issue 1, 2013, Pages 206-213

  Zheng, Qing you ^a   Li, Ping ping ^b   Jin, Feng suo ^c   Yao, Chen ^d   Zhang, Guo hui ^a   Zang, Tong ^a   Ai, Xing ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

^d NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis and bladder cancer; ASK1 JNK signaling; ER stress; Ursolic acid

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; BIM PROTEIN; CASPASE 3; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PROTEIN IRE1; SALUBRINAL; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; URSOLIC ACID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOACCUMULATION; BLADDER CANCER; CANCER CELL; CELL ACTIVITY; CELL CULTURE; CELL FRACTIONATION; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG INHIBITION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CELL LINE, TUMOR; CINNAMATES; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASE 5; MEMBRANE PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THIOUREA; TNF RECEPTOR-ASSOCIATED FACTOR 2; TRANSCRIPTION FACTOR CHOP; TRITERPENES; URINARY BLADDER NEOPLASMS;

EID: 84867605425     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.09.012     Document Type: Article

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