Mechanisms for ribotoxin-induced ribosomal RNA cleavage

Toxicology and Applied Pharmacology

Volumn 265, Issue 1, 2012, Pages 10-18

  He, Kaiyu ^a,c   Zhou, Hui Ren ^b   Pestka, James J ^a,b,c  

^a Department of Microbiology and Molecular Genetics ^*  (United States)

^b Food Science and Human Nutrition   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Anisomycin; Apoptosis; P53; Ribosomal rna; Ribosome; Ribotoxin; Ricin; RRNA; Trichothecene

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANISOMYCIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CASPASE 8; CASPASE 9; CATHEPSIN B; CATHEPSIN L; DOUBLE STRANDED RNA; HEMATOPOIETIC CELL KINASE; MITOGEN ACTIVATED PROTEIN KINASE; RIBOSOME RNA; RICIN; SATRATOXIN G; SYNAPTOPHYSIN; TOXIN; TYPE B TRICHOTHECENE DEOXYNIVALENOL; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CAPILLARY ELECTROPHORESIS; CONTROLLED STUDY; GENOTOXICITY; MACROPHAGE; MOUSE; NONHUMAN; RNA CLEAVAGE;

ANIMALS; ANISOMYCIN; APOPTOSIS; BLOTTING, WESTERN; CASPASE 8; CATHEPSIN L; CELLS, CULTURED; ENZYME ACTIVATION; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NUCLEIC ACID SYNTHESIS INHIBITORS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-HCK; RICIN; RNA CLEAVAGE; RNA, RIBOSOMAL; TRICHOTHECENES; TUMOR SUPPRESSOR PROTEIN P53;

MURINAE;

EID: 84867593175     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.09.017     Document Type: Article

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