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Volumn 7, Issue 10, 2012, Pages

The Peptide Specificity of the Endogenous T Follicular Helper Cell Repertoire Generated after Protein Immunization

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR5; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MALTOSE BINDING PROTEIN; TETRAMER;

EID: 84867540112     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046952     Document Type: Article
Times cited : (8)

References (73)
  • 1
    • 85158921979 scopus 로고    scopus 로고
    • Vaccine Immunology
    • In: Plotkin S, editor, 5 ed. Philadelphia: Saunders Elsevier
    • Siegrist C (2008) Vaccine Immunology. In: Plotkin S, editor. Vaccines: Expert Consult. 5 ed. Philadelphia: Saunders Elsevier. pp. 17-36.
    • (2008) Vaccines: Expert Consult , pp. 17-36
    • Siegrist, C.1
  • 2
    • 77954357410 scopus 로고    scopus 로고
    • Correlates of protection induced by vaccination
    • Plotkin SA, (2010) Correlates of protection induced by vaccination. Clin Vaccine Immunol 17: 1055-1065.
    • (2010) Clin Vaccine Immunol , vol.17 , pp. 1055-1065
    • Plotkin, S.A.1
  • 3
    • 44649180474 scopus 로고    scopus 로고
    • Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities
    • Sette A, Moutaftsi M, Moyron-Quiroz J, McCausland MM, Davies DH, et al. (2008) Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities. Immunity 28: 847-858.
    • (2008) Immunity , vol.28 , pp. 847-858
    • Sette, A.1    Moutaftsi, M.2    Moyron-Quiroz, J.3    McCausland, M.M.4    Davies, D.H.5
  • 4
    • 33846400415 scopus 로고    scopus 로고
    • The germinal center response is impaired in the absence of T cell-expressed CXCR5
    • Arnold CN, Campbell DJ, Lipp M, Butcher EC, (2007) The germinal center response is impaired in the absence of T cell-expressed CXCR5. Eur J Immunol 37: 100-109.
    • (2007) Eur J Immunol , vol.37 , pp. 100-109
    • Arnold, C.N.1    Campbell, D.J.2    Lipp, M.3    Butcher, E.C.4
  • 5
    • 77958134778 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction
    • Rolf J, Bell SE, Kovesdi D, Janas ML, Soond DR, et al. (2010) Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction. J Immunol 185: 4042-4052.
    • (2010) J Immunol , vol.185 , pp. 4042-4052
    • Rolf, J.1    Bell, S.E.2    Kovesdi, D.3    Janas, M.L.4    Soond, D.R.5
  • 7
    • 78049456523 scopus 로고    scopus 로고
    • The germinal center reaction
    • Gatto D, Brink R, (2010) The germinal center reaction. J Allergy Clin Immunol 126: 898-907 quiz 908-899.
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 898-907
    • Gatto, D.1    Brink, R.2
  • 8
    • 38049144850 scopus 로고    scopus 로고
    • Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation
    • Haynes NM, Allen CD, Lesley R, Ansel KM, Killeen N, et al. (2007) Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation. J Immunol 179: 5099-5108.
    • (2007) J Immunol , vol.179 , pp. 5099-5108
    • Haynes, N.M.1    Allen, C.D.2    Lesley, R.3    Ansel, K.M.4    Killeen, N.5
  • 9
    • 24744448228 scopus 로고    scopus 로고
    • Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help
    • Hardtke S, Ohl L, Forster R, (2005) Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help. Blood 106: 1924-1931.
    • (2005) Blood , vol.106 , pp. 1924-1931
    • Hardtke, S.1    Ohl, L.2    Forster, R.3
  • 10
    • 79959342619 scopus 로고    scopus 로고
    • Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone
    • Kerfoot SM, Yaari G, Patel JR, Johnson KL, Gonzalez DG, et al. (2011) Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone. Immunity 34: 947-960.
    • (2011) Immunity , vol.34 , pp. 947-960
    • Kerfoot, S.M.1    Yaari, G.2    Patel, J.R.3    Johnson, K.L.4    Gonzalez, D.G.5
  • 12
    • 80051618656 scopus 로고    scopus 로고
    • Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation
    • Goenka R, Barnett LG, Silver JS, O'Neill PJ, Hunter CA, et al. (2011) Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation. J Immunol 187: 1091-1095.
    • (2011) J Immunol , vol.187 , pp. 1091-1095
    • Goenka, R.1    Barnett, L.G.2    Silver, J.S.3    O'Neill, P.J.4    Hunter, C.A.5
  • 13
    • 77955924180 scopus 로고    scopus 로고
    • Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling
    • Deenick EK, Chan A, Ma CS, Gatto D, Schwartzberg PL, et al. (2010) Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling. Immunity 33: 241-253.
    • (2010) Immunity , vol.33 , pp. 241-253
    • Deenick, E.K.1    Chan, A.2    Ma, C.S.3    Gatto, D.4    Schwartzberg, P.L.5
  • 14
    • 79959328032 scopus 로고    scopus 로고
    • ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
    • Choi YS, Kageyama R, Eto D, Escobar TC, Johnston RJ, et al. (2011) ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity 34: 932-946.
    • (2011) Immunity , vol.34 , pp. 932-946
    • Choi, Y.S.1    Kageyama, R.2    Eto, D.3    Escobar, T.C.4    Johnston, R.J.5
  • 15
    • 79959343565 scopus 로고    scopus 로고
    • Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity
    • Kitano M, Moriyama S, Ando Y, Hikida M, Mori Y, et al. (2011) Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity. Immunity 34: 961-972.
    • (2011) Immunity , vol.34 , pp. 961-972
    • Kitano, M.1    Moriyama, S.2    Ando, Y.3    Hikida, M.4    Mori, Y.5
  • 16
    • 65549134481 scopus 로고    scopus 로고
    • T follicular helper cells differentiate from Th2 cells in response to helminth antigens
    • Zaretsky AG, Taylor JJ, King IL, Marshall FA, Mohrs M, et al. (2009) T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J Exp Med 206: 991-999.
    • (2009) J Exp Med , vol.206 , pp. 991-999
    • Zaretsky, A.G.1    Taylor, J.J.2    King, I.L.3    Marshall, F.A.4    Mohrs, M.5
  • 17
    • 80053058970 scopus 로고    scopus 로고
    • B cells and TCR avidity determine distinct functions of CD4+ T cells in retroviral infection
    • Ploquin MJ, Eksmond U, Kassiotis G, (2011) B cells and TCR avidity determine distinct functions of CD4+ T cells in retroviral infection. J Immunol 187: 3321-3330.
    • (2011) J Immunol , vol.187 , pp. 3321-3330
    • Ploquin, M.J.1    Eksmond, U.2    Kassiotis, G.3
  • 18
    • 53649107278 scopus 로고    scopus 로고
    • SAP-controlled T-B cell interactions underlie germinal centre formation
    • Qi H, Cannons JL, Klauschen F, Schwartzberg PL, Germain RN, (2008) SAP-controlled T-B cell interactions underlie germinal centre formation. Nature 455: 764-769.
    • (2008) Nature , vol.455 , pp. 764-769
    • Qi, H.1    Cannons, J.L.2    Klauschen, F.3    Schwartzberg, P.L.4    Germain, R.N.5
  • 19
    • 33745032268 scopus 로고    scopus 로고
    • SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation
    • Cannons JL, Yu LJ, Jankovic D, Crotty S, Horai R, et al. (2006) SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation. J Exp Med 203: 1551-1565.
    • (2006) J Exp Med , vol.203 , pp. 1551-1565
    • Cannons, J.L.1    Yu, L.J.2    Jankovic, D.3    Crotty, S.4    Horai, R.5
  • 20
    • 76949091588 scopus 로고    scopus 로고
    • Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84
    • Cannons JL, Qi H, Lu KT, Dutta M, Gomez-Rodriguez J, et al. (2010) Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84. Immunity 32: 253-265.
    • (2010) Immunity , vol.32 , pp. 253-265
    • Cannons, J.L.1    Qi, H.2    Lu, K.T.3    Dutta, M.4    Gomez-Rodriguez, J.5
  • 21
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty S, (2011) Follicular helper CD4 T cells (TFH). Annu Rev Immunol 29: 621-663.
    • (2011) Annu Rev Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 22
    • 82055177182 scopus 로고    scopus 로고
    • How T cells earn the follicular rite of passage
    • Vinuesa CG, Cyster JG, (2011) How T cells earn the follicular rite of passage. Immunity 35: 671-680.
    • (2011) Immunity , vol.35 , pp. 671-680
    • Vinuesa, C.G.1    Cyster, J.G.2
  • 23
    • 79956079578 scopus 로고    scopus 로고
    • Germinal center B and follicular helper T cells: siblings, cousins or just good friends
    • Nutt SL, Tarlinton DM, (2011) Germinal center B and follicular helper T cells: siblings, cousins or just good friends? Nat Immunol 12: 472-477.
    • (2011) Nat Immunol , vol.12 , pp. 472-477
    • Nutt, S.L.1    Tarlinton, D.M.2
  • 24
    • 79951672553 scopus 로고    scopus 로고
    • Regulation of T follicular helper cell formation and function by antigen presenting cells
    • Deenick EK, Ma CS, Brink R, Tangye SG, (2011) Regulation of T follicular helper cell formation and function by antigen presenting cells. Curr Opin Immunol 23: 111-118.
    • (2011) Curr Opin Immunol , vol.23 , pp. 111-118
    • Deenick, E.K.1    Ma, C.S.2    Brink, R.3    Tangye, S.G.4
  • 25
    • 77955487468 scopus 로고    scopus 로고
    • Signals that influence T follicular helper cell differentiation and function
    • Linterman MA, Vinuesa CG, (2010) Signals that influence T follicular helper cell differentiation and function. Semin Immunopathol 32: 183-196.
    • (2010) Semin Immunopathol , vol.32 , pp. 183-196
    • Linterman, M.A.1    Vinuesa, C.G.2
  • 26
    • 41549131849 scopus 로고    scopus 로고
    • T follicular helper (TFH) cells in normal and dysregulated immune responses
    • King C, Tangye SG, Mackay CR, (2008) T follicular helper (TFH) cells in normal and dysregulated immune responses. Annu Rev Immunol 26: 741-766.
    • (2008) Annu Rev Immunol , vol.26 , pp. 741-766
    • King, C.1    Tangye, S.G.2    Mackay, C.R.3
  • 27
    • 84859708611 scopus 로고    scopus 로고
    • The 1-1-1 fallacy
    • Crotty S, (2012) The 1-1-1 fallacy. Immunol Rev 247: 133-142.
    • (2012) Immunol Rev , vol.247 , pp. 133-142
    • Crotty, S.1
  • 28
    • 77955280012 scopus 로고    scopus 로고
    • Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)
    • Yusuf I, Kageyama R, Monticelli L, Johnston RJ, Ditoro D, et al. (2010) Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150). J Immunol 185: 190-202.
    • (2010) J Immunol , vol.185 , pp. 190-202
    • Yusuf, I.1    Kageyama, R.2    Monticelli, L.3    Johnston, R.J.4    Ditoro, D.5
  • 29
    • 80655126713 scopus 로고    scopus 로고
    • Mass spectrometry analysis and quantitation of peptides presented on the MHC II molecules of mouse spleen dendritic cells
    • Bozzacco L, Yu H, Zebroski HA, Dengjel J, Deng H, et al. (2011) Mass spectrometry analysis and quantitation of peptides presented on the MHC II molecules of mouse spleen dendritic cells. J Proteome Res 10: 5016-5030.
    • (2011) J Proteome Res , vol.10 , pp. 5016-5030
    • Bozzacco, L.1    Yu, H.2    Zebroski, H.A.3    Dengjel, J.4    Deng, H.5
  • 30
    • 0032519410 scopus 로고    scopus 로고
    • Antigen presentation by dendritic cells focuses T cell responses against immunodominant peptides: studies in the hen egg-white lysozyme (HEL) model
    • Gapin L, Bravo de Alba Y, Casrouge A, Cabaniols JP, Kourilsky P, et al. (1998) Antigen presentation by dendritic cells focuses T cell responses against immunodominant peptides: studies in the hen egg-white lysozyme (HEL) model. J Immunol 160: 1555-1564.
    • (1998) J Immunol , vol.160 , pp. 1555-1564
    • Gapin, L.1    Bravo de Alba, Y.2    Casrouge, A.3    Cabaniols, J.P.4    Kourilsky, P.5
  • 31
    • 0027267589 scopus 로고
    • Suppressive effect of antibody on processing of T cell epitopes
    • Watts C, Lanzavecchia A, (1993) Suppressive effect of antibody on processing of T cell epitopes. J Exp Med 178: 1459-1463.
    • (1993) J Exp Med , vol.178 , pp. 1459-1463
    • Watts, C.1    Lanzavecchia, A.2
  • 32
    • 0029035307 scopus 로고
    • Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants
    • Simitsek PD, Campbell DG, Lanzavecchia A, Fairweather N, Watts C, (1995) Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants. J Exp Med 181: 1957-1963.
    • (1995) J Exp Med , vol.181 , pp. 1957-1963
    • Simitsek, P.D.1    Campbell, D.G.2    Lanzavecchia, A.3    Fairweather, N.4    Watts, C.5
  • 33
    • 0037136285 scopus 로고    scopus 로고
    • Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation
    • Lennon-Dumenil AM, Bakker AH, Maehr R, Fiebiger E, Overkleeft HS, et al. (2002) Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation. J Exp Med 196: 529-540.
    • (2002) J Exp Med , vol.196 , pp. 529-540
    • Lennon-Dumenil, A.M.1    Bakker, A.H.2    Maehr, R.3    Fiebiger, E.4    Overkleeft, H.S.5
  • 34
    • 42349090206 scopus 로고    scopus 로고
    • The role of B lymphocytes as antigen-presenting cells
    • Chen X, Jensen PE, (2008) The role of B lymphocytes as antigen-presenting cells. Arch Immunol Ther Exp (Warsz) 56: 77-83.
    • (2008) Arch Immunol Ther Exp (Warsz) , vol.56 , pp. 77-83
    • Chen, X.1    Jensen, P.E.2
  • 36
    • 3042515664 scopus 로고    scopus 로고
    • The expression of HLA-DO (H2-O) in B lymphocytes
    • Chen X, Jensen PE, (2004) The expression of HLA-DO (H2-O) in B lymphocytes. Immunol Res 29: 19-28.
    • (2004) Immunol Res , vol.29 , pp. 19-28
    • Chen, X.1    Jensen, P.E.2
  • 37
    • 77955230565 scopus 로고    scopus 로고
    • Generation of MHC class II-peptide ligands for CD4 T-cell allorecognition of MHC class II molecules
    • Leddon SA, Sant AJ, (2010) Generation of MHC class II-peptide ligands for CD4 T-cell allorecognition of MHC class II molecules. Curr Opin Organ Transplant 15: 505-511.
    • (2010) Curr Opin Organ Transplant , vol.15 , pp. 505-511
    • Leddon, S.A.1    Sant, A.J.2
  • 38
    • 26244441527 scopus 로고    scopus 로고
    • Right place, right time, right peptide: DO keeps DM focused
    • Denzin LK, Fallas JL, Prendes M, Yi W, (2005) Right place, right time, right peptide: DO keeps DM focused. Immunol Rev 207: 279-292.
    • (2005) Immunol Rev , vol.207 , pp. 279-292
    • Denzin, L.K.1    Fallas, J.L.2    Prendes, M.3    Yi, W.4
  • 39
    • 34548736008 scopus 로고    scopus 로고
    • Recent advances in antigen processing and presentation
    • Jensen PE, (2007) Recent advances in antigen processing and presentation. Nat Immunol 8: 1041-1048.
    • (2007) Nat Immunol , vol.8 , pp. 1041-1048
    • Jensen, P.E.1
  • 40
    • 40749104640 scopus 로고    scopus 로고
    • An MHC class II restriction bias in CD4 T cell responses toward I-A is altered to I-E in DM-deficient mice
    • Menges PR, Jenks SA, Bikoff EK, Friedmann DR, Knowlden ZA, et al. (2008) An MHC class II restriction bias in CD4 T cell responses toward I-A is altered to I-E in DM-deficient mice. J Immunol 180: 1619-1633.
    • (2008) J Immunol , vol.180 , pp. 1619-1633
    • Menges, P.R.1    Jenks, S.A.2    Bikoff, E.K.3    Friedmann, D.R.4    Knowlden, Z.A.5
  • 41
    • 0025964640 scopus 로고
    • Identification of eight determinants in the hemagglutinin molecule of influenza virus A/PR/8/34 (H1N1) which are recognized by class II-restricted T cells from BALB/c mice
    • Gerhard W, Haberman AM, Scherle PA, Taylor AH, Palladino G, et al. (1991) Identification of eight determinants in the hemagglutinin molecule of influenza virus A/PR/8/34 (H1N1) which are recognized by class II-restricted T cells from BALB/c mice. J Virol 65: 364-372.
    • (1991) J Virol , vol.65 , pp. 364-372
    • Gerhard, W.1    Haberman, A.M.2    Scherle, P.A.3    Taylor, A.H.4    Palladino, G.5
  • 42
    • 57049128692 scopus 로고    scopus 로고
    • Novel T-cell epitopes of ovalbumin in BALB/c mouse: potential for peptide-immunotherapy
    • Yang M, Mine Y, (2009) Novel T-cell epitopes of ovalbumin in BALB/c mouse: potential for peptide-immunotherapy. Biochem Biophys Res Commun 378: 203-208.
    • (2009) Biochem Biophys Res Commun , vol.378 , pp. 203-208
    • Yang, M.1    Mine, Y.2
  • 43
    • 0001123104 scopus 로고    scopus 로고
    • IL-4 rapidly produced by V beta 4 V alpha 8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice
    • Launois P, Maillard I, Pingel S, Swihart KG, Xenarios I, et al. (1997) IL-4 rapidly produced by V beta 4 V alpha 8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice. Immunity 6: 541-549.
    • (1997) Immunity , vol.6 , pp. 541-549
    • Launois, P.1    Maillard, I.2    Pingel, S.3    Swihart, K.G.4    Xenarios, I.5
  • 44
    • 77953957400 scopus 로고    scopus 로고
    • Analyses of the specificity of CD4 T cells during the primary immune response to influenza virus reveals dramatic MHC-linked asymmetries in reactivity to individual viral proteins
    • Nayak JL, Richards KA, Chaves FA, Sant AJ, (2010) Analyses of the specificity of CD4 T cells during the primary immune response to influenza virus reveals dramatic MHC-linked asymmetries in reactivity to individual viral proteins. Viral Immunol 23: 169-180.
    • (2010) Viral Immunol , vol.23 , pp. 169-180
    • Nayak, J.L.1    Richards, K.A.2    Chaves, F.A.3    Sant, A.J.4
  • 45
    • 34447250320 scopus 로고    scopus 로고
    • Direct ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza virus hemagglutinin
    • Richards KA, Chaves FA, Krafcik FR, Topham DJ, Lazarski CA, et al. (2007) Direct ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza virus hemagglutinin. J Virol 81: 7608-7619.
    • (2007) J Virol , vol.81 , pp. 7608-7619
    • Richards, K.A.1    Chaves, F.A.2    Krafcik, F.R.3    Topham, D.J.4    Lazarski, C.A.5
  • 46
    • 0020606071 scopus 로고
    • The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product
    • Marrack P, Endres R, Shimonkevitz R, Zlotnik A, Dialynas D, et al. (1983) The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med 158: 1077-1091.
    • (1983) J Exp Med , vol.158 , pp. 1077-1091
    • Marrack, P.1    Endres, R.2    Shimonkevitz, R.3    Zlotnik, A.4    Dialynas, D.5
  • 47
    • 0024043076 scopus 로고
    • Interaction of an immunodominant epitope with Ia molecules in T-cell activation
    • Adorini L, Sette A, Buus S, Grey HM, Darsley M, et al. (1988) Interaction of an immunodominant epitope with Ia molecules in T-cell activation. Proc Natl Acad Sci U S A 85: 5181-5185.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 5181-5185
    • Adorini, L.1    Sette, A.2    Buus, S.3    Grey, H.M.4    Darsley, M.5
  • 48
    • 22544455376 scopus 로고    scopus 로고
    • The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance
    • Lazarski CA, Chaves FA, Jenks SA, Wu S, Richards KA, et al. (2005) The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance. Immunity 23: 29-40.
    • (2005) Immunity , vol.23 , pp. 29-40
    • Lazarski, C.A.1    Chaves, F.A.2    Jenks, S.A.3    Wu, S.4    Richards, K.A.5
  • 49
    • 84855857028 scopus 로고    scopus 로고
    • Infection with seasonal influenza virus elicits CD4 T cells specific for genetically conserved epitopes that can be rapidly mobilized for protective immunity to pandemic H1N1 influenza virus
    • Alam S, Sant AJ, (2011) Infection with seasonal influenza virus elicits CD4 T cells specific for genetically conserved epitopes that can be rapidly mobilized for protective immunity to pandemic H1N1 influenza virus. J Virol 85: 13310-13321.
    • (2011) J Virol , vol.85 , pp. 13310-13321
    • Alam, S.1    Sant, A.J.2
  • 50
    • 66649110510 scopus 로고    scopus 로고
    • Abortive activation of CD4 T cell responses during competitive priming in vivo
    • Weaver JM, Chaves FA, Sant AJ, (2009) Abortive activation of CD4 T cell responses during competitive priming in vivo. Proc Natl Acad Sci U S A 106: 8647-8652.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 8647-8652
    • Weaver, J.M.1    Chaves, F.A.2    Sant, A.J.3
  • 51
    • 46749115446 scopus 로고    scopus 로고
    • A fundamental role for interleukin-21 in the generation of T follicular helper cells
    • Vogelzang A, McGuire HM, Yu D, Sprent J, Mackay CR, et al. (2008) A fundamental role for interleukin-21 in the generation of T follicular helper cells. Immunity 29: 127-137.
    • (2008) Immunity , vol.29 , pp. 127-137
    • Vogelzang, A.1    McGuire, H.M.2    Yu, D.3    Sprent, J.4    Mackay, C.R.5
  • 52
    • 84255178198 scopus 로고    scopus 로고
    • Early Th1 cell differentiation is marked by a Tfh cell-like transition
    • Nakayamada S, Kanno Y, Takahashi H, Jankovic D, Lu KT, et al. (2011) Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity 35: 919-931.
    • (2011) Immunity , vol.35 , pp. 919-931
    • Nakayamada, S.1    Kanno, Y.2    Takahashi, H.3    Jankovic, D.4    Lu, K.T.5
  • 53
    • 46749151286 scopus 로고    scopus 로고
    • Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
    • Nurieva RI, Chung Y, Hwang D, Yang XO, Kang HS, et al. (2008) Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 29: 138-149.
    • (2008) Immunity , vol.29 , pp. 138-149
    • Nurieva, R.I.1    Chung, Y.2    Hwang, D.3    Yang, X.O.4    Kang, H.S.5
  • 54
    • 62849126473 scopus 로고    scopus 로고
    • The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding
    • Fazilleau N, McHeyzer-Williams LJ, Rosen H, McHeyzer-Williams MG, (2009) The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding. Nat Immunol 10: 375-384.
    • (2009) Nat Immunol , vol.10 , pp. 375-384
    • Fazilleau, N.1    McHeyzer-Williams, L.J.2    Rosen, H.3    McHeyzer-Williams, M.G.4
  • 56
    • 84859897308 scopus 로고    scopus 로고
    • The development and fate of follicular helper T cells defined by an IL-21 reporter mouse
    • GT TB
    • Luthje K, Kallies A, Shimohakamada Y, GT TB, Light A, et al. (2012) The development and fate of follicular helper T cells defined by an IL-21 reporter mouse. Nat Immunol 13: 491-498.
    • (2012) Nat Immunol , vol.13 , pp. 491-498
    • Luthje, K.1    Kallies, A.2    Shimohakamada, Y.3    Light, A.4
  • 57
    • 62849090439 scopus 로고    scopus 로고
    • Cytokine-secreting follicular T cells shape the antibody repertoire
    • Reinhardt RL, Liang HE, Locksley RM, (2009) Cytokine-secreting follicular T cells shape the antibody repertoire. Nat Immunol 10: 385-393.
    • (2009) Nat Immunol , vol.10 , pp. 385-393
    • Reinhardt, R.L.1    Liang, H.E.2    Locksley, R.M.3
  • 58
    • 83855163410 scopus 로고    scopus 로고
    • Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity
    • Liang HE, Reinhardt RL, Bando JK, Sullivan BM, Ho IC, et al. (2012) Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity. Nat Immunol 13: 58-66.
    • (2012) Nat Immunol , vol.13 , pp. 58-66
    • Liang, H.E.1    Reinhardt, R.L.2    Bando, J.K.3    Sullivan, B.M.4    Ho, I.C.5
  • 59
    • 69249109601 scopus 로고    scopus 로고
    • Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
    • Johnston RJ, Poholek AC, DiToro D, Yusuf I, Eto D, et al. (2009) Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science 325: 1006-1010.
    • (2009) Science , vol.325 , pp. 1006-1010
    • Johnston, R.J.1    Poholek, A.C.2    DiToro, D.3    Yusuf, I.4    Eto, D.5
  • 60
    • 10744227803 scopus 로고    scopus 로고
    • Comparison of the ELISPOT and cytokine flow cytometry assays for the enumeration of antigen-specific T cells
    • Karlsson AC, Martin JN, Younger SR, Bredt BM, Epling L, et al. (2003) Comparison of the ELISPOT and cytokine flow cytometry assays for the enumeration of antigen-specific T cells. J Immunol Methods 283: 141-153.
    • (2003) J Immunol Methods , vol.283 , pp. 141-153
    • Karlsson, A.C.1    Martin, J.N.2    Younger, S.R.3    Bredt, B.M.4    Epling, L.5
  • 61
    • 33845456179 scopus 로고    scopus 로고
    • A comparison of standard immunogenicity assays for monitoring HIV type 1 gag-specific T cell responses in Ad5 HIV Type 1 gag vaccinated human subjects
    • Tobery TW, Dubey SA, Anderson K, Freed DC, Cox KS, et al. (2006) A comparison of standard immunogenicity assays for monitoring HIV type 1 gag-specific T cell responses in Ad5 HIV Type 1 gag vaccinated human subjects. AIDS Res Hum Retroviruses 22: 1081-1090.
    • (2006) AIDS Res Hum Retroviruses , vol.22 , pp. 1081-1090
    • Tobery, T.W.1    Dubey, S.A.2    Anderson, K.3    Freed, D.C.4    Cox, K.S.5
  • 62
    • 26244456560 scopus 로고    scopus 로고
    • Monitoring of cellular responses after vaccination against tetanus toxoid: comparison of the measurement of IFN-gamma production by ELISA, ELISPOT, flow cytometry and real-time PCR
    • Tassignon J, Burny W, Dahmani S, Zhou L, Stordeur P, et al. (2005) Monitoring of cellular responses after vaccination against tetanus toxoid: comparison of the measurement of IFN-gamma production by ELISA, ELISPOT, flow cytometry and real-time PCR. J Immunol Methods 305: 188-198.
    • (2005) J Immunol Methods , vol.305 , pp. 188-198
    • Tassignon, J.1    Burny, W.2    Dahmani, S.3    Zhou, L.4    Stordeur, P.5
  • 63
    • 79955024763 scopus 로고    scopus 로고
    • The memory phase of the CD4 T-cell response to influenza virus infection maintains its diverse antigen specificity
    • Richards KA, Chaves FA, Sant AJ, (2011) The memory phase of the CD4 T-cell response to influenza virus infection maintains its diverse antigen specificity. Immunology 133: 246-256.
    • (2011) Immunology , vol.133 , pp. 246-256
    • Richards, K.A.1    Chaves, F.A.2    Sant, A.J.3
  • 64
    • 80052555420 scopus 로고    scopus 로고
    • Different patterns of peripheral migration by memory CD4+ and CD8+ T cells
    • Gebhardt T, Whitney PG, Zaid A, Mackay LK, Brooks AG, et al. (2011) Different patterns of peripheral migration by memory CD4+ and CD8+ T cells. Nature 477: 216-219.
    • (2011) Nature , vol.477 , pp. 216-219
    • Gebhardt, T.1    Whitney, P.G.2    Zaid, A.3    Mackay, L.K.4    Brooks, A.G.5
  • 66
    • 0035282433 scopus 로고    scopus 로고
    • Visualizing the generation of memory CD4 T cells in the whole body
    • Reinhardt RL, Khoruts A, Merica R, Zell T, Jenkins MK, (2001) Visualizing the generation of memory CD4 T cells in the whole body. Nature 410: 101-105.
    • (2001) Nature , vol.410 , pp. 101-105
    • Reinhardt, R.L.1    Khoruts, A.2    Merica, R.3    Zell, T.4    Jenkins, M.K.5
  • 70
    • 66749147292 scopus 로고    scopus 로고
    • Integrin function in T-cell homing to lymphoid and nonlymphoid sites: getting there and staying there
    • Denucci CC, Mitchell JS, Shimizu Y, (2009) Integrin function in T-cell homing to lymphoid and nonlymphoid sites: getting there and staying there. Crit Rev Immunol 29: 87-109.
    • (2009) Crit Rev Immunol , vol.29 , pp. 87-109
    • Denucci, C.C.1    Mitchell, J.S.2    Shimizu, Y.3
  • 71
    • 34548747629 scopus 로고    scopus 로고
    • Migration and accumulation of effector CD4+ T cells in nonlymphoid tissues
    • McLachlan JB, Jenkins MK, (2007) Migration and accumulation of effector CD4+ T cells in nonlymphoid tissues. Proc Am Thorac Soc 4: 439-442.
    • (2007) Proc Am Thorac Soc , vol.4 , pp. 439-442
    • McLachlan, J.B.1    Jenkins, M.K.2
  • 72
    • 33646697124 scopus 로고    scopus 로고
    • The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability
    • Lazarski CA, Chaves FA, Sant AJ, (2006) The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability. J Exp Med 203: 1319-1328.
    • (2006) J Exp Med , vol.203 , pp. 1319-1328
    • Lazarski, C.A.1    Chaves, F.A.2    Sant, A.J.3
  • 73
    • 84860320829 scopus 로고    scopus 로고
    • The Utility and Limitations of Current Web-Available Algorithms To Predict Peptides Recognized by CD4 T Cells in Response to Pathogen Infection
    • Chaves FA, Lee AH, Nayak JL, Richards KA, Sant AJ, (2012) The Utility and Limitations of Current Web-Available Algorithms To Predict Peptides Recognized by CD4 T Cells in Response to Pathogen Infection. J Immunol.
    • (2012) J Immunol
    • Chaves, F.A.1    Lee, A.H.2    Nayak, J.L.3    Richards, K.A.4    Sant, A.J.5


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