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Volumn 203, Issue 5, 2006, Pages 1319-1328

The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN DM; PROTEOLIPID PROTEIN; UNCLASSIFIED DRUG;

EID: 33646697124     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20060058     Document Type: Article
Times cited : (58)

References (51)
  • 1
    • 0032168861 scopus 로고    scopus 로고
    • The structure of HLA-DM, the peptide exchange catalyst that loads antigen onto class II MHC molecules during antigen presentation
    • Mosyak, L., D.M. Zaller, and D.C. Wiley. 1998. The structure of HLA-DM, the peptide exchange catalyst that loads antigen onto class II MHC molecules during antigen presentation. Immunity. 9:377-383.
    • (1998) Immunity , vol.9 , pp. 377-383
    • Mosyak, L.1    Zaller, D.M.2    Wiley, D.C.3
  • 3
    • 0028981178 scopus 로고
    • HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading
    • Denzin, L.K., and P. Cresswell. 1995. HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading. Cell. 82:155-165.
    • (1995) Cell , vol.82 , pp. 155-165
    • Denzin, L.K.1    Cresswell, P.2
  • 4
    • 0029084023 scopus 로고
    • DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide
    • Sherman, M.A., D.A. Weber, and P.E. Jensen. 1995. DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide. Immunity. 3:197-205.
    • (1995) Immunity , vol.3 , pp. 197-205
    • Sherman, M.A.1    Weber, D.A.2    Jensen, P.E.3
  • 5
    • 0030443233 scopus 로고    scopus 로고
    • DM-mediated release of a naturally occurring invariant chain degradation intermediate from MHC class II molecules
    • Stebbins, C.C., M.E. Peterson, W.M. Suh, and A.J. Sant. 1996. DM-mediated release of a naturally occurring invariant chain degradation intermediate from MHC class II molecules. J. Immunol. 157:4892-4898.
    • (1996) J. Immunol. , vol.157 , pp. 4892-4898
    • Stebbins, C.C.1    Peterson, M.E.2    Suh, W.M.3    Sant, A.J.4
  • 6
    • 0033713296 scopus 로고    scopus 로고
    • Determination of the HLA-DM interaction site on HLA-DR molecules
    • Doebele, R.C., R. Busch, H.M. Scott, A. Pashine, and E.D. Mellins. 2000. Determination of the HLA-DM interaction site on HLA-DR molecules. Immunity. 13:517-527.
    • (2000) Immunity , vol.13 , pp. 517-527
    • Doebele, R.C.1    Busch, R.2    Scott, H.M.3    Pashine, A.4    Mellins, E.D.5
  • 7
    • 0037099720 scopus 로고    scopus 로고
    • Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysis
    • Stratikos, E., L. Mosyak, D.M. Zaller, and D.C. Wiley. 2002. Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysis. J. Exp. Med. 196:173-183.
    • (2002) J. Exp. Med. , vol.196 , pp. 173-183
    • Stratikos, E.1    Mosyak, L.2    Zaller, D.M.3    Wiley, D.C.4
  • 8
    • 0030458137 scopus 로고    scopus 로고
    • HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules
    • Denzin, L.K., C. Hammond, and P. Cresswell. 1996. HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules. J. Exp. Med. 184:2153-2165.
    • (1996) J. Exp. Med. , vol.184 , pp. 2153-2165
    • Denzin, L.K.1    Hammond, C.2    Cresswell, P.3
  • 9
    • 0031080953 scopus 로고    scopus 로고
    • How HLA-DM edits the MHC class II peptide repertoire: Survival of the fittest?
    • Kropshofer, H., G.J. Hammerling, and A.B. Vogt. 1997. How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest? Immunol. Today. 18:77-82.
    • (1997) Immunol. Today , vol.18 , pp. 77-82
    • Kropshofer, H.1    Hammerling, G.J.2    Vogt, A.B.3
  • 11
    • 0029824101 scopus 로고    scopus 로고
    • Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM
    • Weber, D.A., B.D. Evavold, and P.E. Jensen. 1996. Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM. Science. 274:618-620.
    • (1996) Science , vol.274 , pp. 618-620
    • Weber, D.A.1    Evavold, B.D.2    Jensen, P.E.3
  • 14
    • 0029853195 scopus 로고    scopus 로고
    • Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules
    • Katz, J.F., C. Stebbins, E. Appella, and A.J. Sant. 1996. Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules. J. Exp. Med. 184:1747-1753.
    • (1996) J. Exp. Med. , vol.184 , pp. 1747-1753
    • Katz, J.F.1    Stebbins, C.2    Appella, E.3    Sant, A.J.4
  • 15
    • 0030990387 scopus 로고    scopus 로고
    • In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DM
    • Lightstone, L., R. Hargreaves, G. Bobek, M. Peterson, G. Aichinger, G. Lombardi, and R. Lechler. 1997. In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DM. Proc. Natl. Acad. Sci. USA. 94:5772-5777.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5772-5777
    • Lightstone, L.1    Hargreaves, R.2    Bobek, G.3    Peterson, M.4    Aichinger, G.5    Lombardi, G.6    Lechler, R.7
  • 18
    • 0031002550 scopus 로고    scopus 로고
    • Presentation of abundant endogenous class II DR-restricted antigens by DM-negative B cell lines
    • Kovats, S., P.E. Whiteley, P. Concannon, A.Y. Rudensky, and J.S. Blum. 1997. Presentation of abundant endogenous class II DR-restricted antigens by DM-negative B cell lines. Eur. J. Immunol. 27:1014-1021.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1014-1021
    • Kovats, S.1    Whiteley, P.E.2    Concannon, P.3    Rudensky, A.Y.4    Blum, J.S.5
  • 19
    • 0035879199 scopus 로고    scopus 로고
    • Cutting edge: Editing of recycling class II:peptide complexes by HLA-DM
    • Pathak, S.S., J.D. Lich, and J.S. Blum. 2001. Cutting edge: editing of recycling class II:peptide complexes by HLA-DM. J. Immunol. 167:632-635.
    • (2001) J. Immunol. , vol.167 , pp. 632-635
    • Pathak, S.S.1    Lich, J.D.2    Blum, J.S.3
  • 21
    • 0029807634 scopus 로고    scopus 로고
    • Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs
    • van Ham, S.M., U. Gruneberg, G. Malcherek, I. Broker, A. Melms, and J. Trowsdale. 1996. Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs. J. Exp. Med. 184:2019-2024.
    • (1996) J. Exp. Med. , vol.184 , pp. 2019-2024
    • Van Ham, S.M.1    Gruneberg, U.2    Malcherek, G.3    Broker, I.4    Melms, A.5    Trowsdale, J.6
  • 22
    • 0036838687 scopus 로고    scopus 로고
    • Structural factors contributing to DM susceptibility of MHC class II/peptide complexes
    • Belmares, M.P., R. Busch, K.W. Wucherpfennig, H.M. McConnell, and E.D. Mellins. 2002. Structural factors contributing to DM susceptibility of MHC class II/peptide complexes. J. Immunol. 169:5109-5117.
    • (2002) J. Immunol. , vol.169 , pp. 5109-5117
    • Belmares, M.P.1    Busch, R.2    Wucherpfennig, K.W.3    McConnell, H.M.4    Mellins, E.D.5
  • 23
    • 0345016487 scopus 로고    scopus 로고
    • Cutting edge: TCR contacts as anchors: Effects on affinity and HLA-DM stability
    • Anderson, M.W., and J. Gorski. 2003. Cutting edge: TCR contacts as anchors: effects on affinity and HLA-DM stability. J. Immunol. 171:5683-5687.
    • (2003) J. Immunol. , vol.171 , pp. 5683-5687
    • Anderson, M.W.1    Gorski, J.2
  • 24
    • 1642495746 scopus 로고    scopus 로고
    • Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain
    • Stratikos, E., D.C. Wiley, and L.J. Stern. 2004. Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain. J. Immunol. 172:1109-1117.
    • (2004) J. Immunol. , vol.172 , pp. 1109-1117
    • Stratikos, E.1    Wiley, D.C.2    Stern, L.J.3
  • 25
    • 0033807322 scopus 로고    scopus 로고
    • DM determines the cryptic and immunodominant fate of T cell epitopes
    • Nanda, N., and A.J. Sant. 2000. DM determines the cryptic and immunodominant fate of T cell epitopes. J. Exp. Med. 192:781-788.
    • (2000) J. Exp. Med. , vol.192 , pp. 781-788
    • Nanda, N.1    Sant, A.J.2
  • 26
    • 0031904199 scopus 로고    scopus 로고
    • Binding affinity independent contribution of peptide length to the stability of peptide-HLA-DR complexes in live antigen presenting cells
    • Siklodi, B., A.B. Vogt, H. Kropshofer, F. Falcioni, M. Molina, D.R. Bolin, R. Campbell, G.J. Hammerling, and Z.A. Nagy. 1998. Binding affinity independent contribution of peptide length to the stability of peptide-HLA-DR complexes in live antigen presenting cells. Hum. Immunol. 59:463-471.
    • (1998) Hum. Immunol. , vol.59 , pp. 463-471
    • Siklodi, B.1    Vogt, A.B.2    Kropshofer, H.3    Falcioni, F.4    Molina, M.5    Bolin, D.R.6    Campbell, R.7    Hammerling, G.J.8    Nagy, Z.A.9
  • 27
    • 0034684671 scopus 로고    scopus 로고
    • HLA-DM recognizes the flexible conformation of major histocompatibility complex class II
    • Chou, C.L., and S. Sadegh-Nasseri. 2000. HLA-DM recognizes the flexible conformation of major histocompatibility complex class II. J. Exp. Med. 192:1697-1706.
    • (2000) J. Exp. Med. , vol.192 , pp. 1697-1706
    • Chou, C.L.1    Sadegh-Nasseri, S.2
  • 28
    • 22544455376 scopus 로고    scopus 로고
    • The kinetic stability of MHC class II: Peptide complexes is a key parameter that dictates immunodominance
    • Lazarski, C.A., F.A. Chaves, S.A. Jenks, S. Wu, K.A. Richards, J.M. Weaver, and A.J. Sant. 2005. The kinetic stability of MHC class II: peptide complexes is a key parameter that dictates immunodominance. Immunity. 23:29-40.
    • (2005) Immunity , vol.23 , pp. 29-40
    • Lazarski, C.A.1    Chaves, F.A.2    Jenks, S.A.3    Wu, S.4    Richards, K.A.5    Weaver, J.M.6    Sant, A.J.7
  • 29
    • 0033807322 scopus 로고    scopus 로고
    • DM determines the cryptic and immunodominant fate of T cell epitopes
    • Nanda, N.K., and A.J. Sant. 2000. DM determines the cryptic and immunodominant fate of T cell epitopes. J. Exp. Med. 192:781-788.
    • (2000) J. Exp. Med. , vol.192 , pp. 781-788
    • Nanda, N.K.1    Sant, A.J.2
  • 30
    • 20444386228 scopus 로고    scopus 로고
    • d MHC class II molecules with I-E-derived sequences promotes production of an active and stable soluble heterodimer without altering peptide-binding specificity
    • d MHC class II molecules with I-E-derived sequences promotes production of an active and stable soluble heterodimer without altering peptide-binding specificity. J. Immunol. Methods. 300:74-92.
    • (2005) J. Immunol. Methods. , vol.300 , pp. 74-92
    • Chaves, F.A.1    Hou, P.2    Wu, S.3    Sant, A.J.4
  • 31
    • 0026912704 scopus 로고
    • Expression of heterologous peptides at two permissive sites of the MalE protein: Antigenicity and immunogenicity of foreign B-cell and T-cell epitopes
    • Martineau, P., J.G. Guillet, C. Leclerc, and M. Hofnung. 1992. Expression of heterologous peptides at two permissive sites of the MalE protein: antigenicity and immunogenicity of foreign B-cell and T-cell epitopes. Gene. 118:151.
    • (1992) Gene , vol.118 , pp. 151
    • Martineau, P.1    Guillet, J.G.2    Leclerc, C.3    Hofnung, M.4
  • 33
    • 0027339408 scopus 로고
    • Th1 and Th2 cell antigen receptors in experimental Leishmaniasis
    • Reiner, S., Z. Wang, F. Hatam, P. Scott, and R.M. Locksley. 1993. Th1 and Th2 cell antigen receptors in experimental Leishmaniasis. Science. 259:1457-1460.
    • (1993) Science , vol.259 , pp. 1457-1460
    • Reiner, S.1    Wang, Z.2    Hatam, F.3    Scott, P.4    Locksley, R.M.5
  • 34
    • 0032033678 scopus 로고    scopus 로고
    • d-peptide complexes reveal that high affinity can be achieved without large anchor residues
    • published erratum appears in Immunity. 1998. 8:531
    • d-peptide complexes reveal that high affinity can be achieved without large anchor residues. Immunity. 8:319-329. (published erratum appears in Immunity. 1998. 8:531)
    • (1998) Immunity , vol.8 , pp. 319-329
    • Scott, C.A.1    Peterson, P.A.2    Teyton, L.3    Wilson, I.A.4
  • 35
    • 20444422540 scopus 로고    scopus 로고
    • Energetics and cooperativity of the hydrogen bonding and anchor interactions that bind peptides to MHC class II protein
    • McFarland, B.J., J.F. Katz, A.J. Sant, and C. Beeson. 2005. Energetics and cooperativity of the hydrogen bonding and anchor interactions that bind peptides to MHC class II protein. J. Mol. Biol. 350:170-183.
    • (2005) J. Mol. Biol. , vol.350 , pp. 170-183
    • McFarland, B.J.1    Katz, J.F.2    Sant, A.J.3    Beeson, C.4
  • 36
    • 0035979230 scopus 로고    scopus 로고
    • Energetic asymmetry among hydrogen bonds in MHC class II:peptide complexes
    • McFarland, B.J., J.F. Katz, C. Beeson, and A.J. Sant. 2001. Energetic asymmetry among hydrogen bonds in MHC class II:peptide complexes. Proc. Natl. Acad. Sci. USA. 98:9231-9236.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9231-9236
    • McFarland, B.J.1    Katz, J.F.2    Beeson, C.3    Sant, A.J.4
  • 37
    • 0347926117 scopus 로고    scopus 로고
    • Formation of two peptide/MHC II isomers is catalyzed differentially by HLA-DM
    • Belmares, M.P., R. Busch, E.D. Mellins, and H.M. McConnell. 2003. Formation of two peptide/MHC II isomers is catalyzed differentially by HLA-DM. Biochemistry. 42:838-847.
    • (2003) Biochemistry , vol.42 , pp. 838-847
    • Belmares, M.P.1    Busch, R.2    Mellins, E.D.3    McConnell, H.M.4
  • 40
    • 0030712935 scopus 로고    scopus 로고
    • Antigen-presenting cells and the selection of immunodominant epitopes
    • Blum, J.S., C. Ma, and S. Kovats. 1997. Antigen-presenting cells and the selection of immunodominant epitopes. Crit. Rev. Immunol. 17:411-417.
    • (1997) Crit. Rev. Immunol. , vol.17 , pp. 411-417
    • Blum, J.S.1    Ma, C.2    Kovats, S.3
  • 41
    • 22544482556 scopus 로고    scopus 로고
    • The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes
    • Sant, A.J., F.A. Chaves, S.A. Jenks, K.A. Richards, P. Menges, J.M. Weaver, and C.A. Lazarski. 2005. The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes. Immunol. Rev. 207:261-278.
    • (2005) Immunol. Rev. , vol.207 , pp. 261-278
    • Sant, A.J.1    Chaves, F.A.2    Jenks, S.A.3    Richards, K.A.4    Menges, P.5    Weaver, J.M.6    Lazarski, C.A.7
  • 42
    • 17644370329 scopus 로고    scopus 로고
    • Cell biology of antigen processing in vitro and in vivo
    • Trombetta, E.S., and I. Mellman. 2005. Cell biology of antigen processing in vitro and in vivo. Annu. Rev. Immunol. 23:975-1028.
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 975-1028
    • Trombetta, E.S.1    Mellman, I.2
  • 43
    • 0030858138 scopus 로고    scopus 로고
    • Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
    • Cella, M., A. Engering, V. Pinet, J. Pieters, and A. Lanzavecchia. 1997. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature. 388:782-787.
    • (1997) Nature , vol.388 , pp. 782-787
    • Cella, M.1    Engering, A.2    Pinet, V.3    Pieters, J.4    Lanzavecchia, A.5
  • 46
    • 0037120052 scopus 로고    scopus 로고
    • + T cells is amplified by prolonged T cell antigen receptor triggering
    • + T cells is amplified by prolonged T cell antigen receptor triggering. J. Exp. Med. 196:793-803.
    • (2002) J. Exp. Med. , vol.196 , pp. 793-803
    • Schrum, A.G.1    Turka, L.A.2
  • 47
    • 0037083665 scopus 로고    scopus 로고
    • Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4(+) T cells
    • Bajenoff, M., O. Wurtz, and S. Guerder. 2002. Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4(+) T cells. J. Immunol. 168:1723-1729.
    • (2002) J. Immunol. , vol.168 , pp. 1723-1729
    • Bajenoff, M.1    Wurtz, O.2    Guerder, S.3
  • 48
    • 0018136078 scopus 로고
    • Affinity chromatographic isolation of the periplasmic maltose binding protein of Escherichia coli
    • Ferenci, T., and U. Klotz. 1978. Affinity chromatographic isolation of the periplasmic maltose binding protein of Escherichia coli. FEBS Lett. 94:213-217.
    • (1978) FEBS Lett. , vol.94 , pp. 213-217
    • Ferenci, T.1    Klotz, U.2
  • 49
    • 0027254482 scopus 로고
    • Major histocompatibility complex class II-restricted presentation of an internally synthesized antigen displays cell-type variability and segregates from the exogenous class II and endogenous class I presentation pathways
    • Loss, G.E., Jr., C.G. Elias, P.E. Fields, R.K. Ribaudo, M. McKisic, and A.J. Sant. 1993. Major histocompatibility complex class II-restricted presentation of an internally synthesized antigen displays cell-type variability and segregates from the exogenous class II and endogenous class I presentation pathways. J. Exp. Med. 178:73-85.
    • (1993) J. Exp. Med. , vol.178 , pp. 73-85
    • Loss Jr., G.E.1    Elias, C.G.2    Fields, P.E.3    Ribaudo, R.K.4    McKisic, M.5    Sant, A.J.6
  • 51
    • 0028330983 scopus 로고
    • T cell receptor recognition of MHC class II alloantigens is highly cell type dependent
    • Katz, J.F., and A.J. Sant. 1994. T cell receptor recognition of MHC class II alloantigens is highly cell type dependent. J. Immunol. 152:1629-1640.
    • (1994) J. Immunol. , vol.152 , pp. 1629-1640
    • Katz, J.F.1    Sant, A.J.2


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