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Angewandte Chemie - International Edition

Volumn 51, Issue 42, 2012, Pages 10647-10651

Metal-bis(2-picolyl)amine complexes as state(T) inhibitors of activated ras protein

(9) Rosnizeck, Ina C a Spoerner, Michael a Harsch, Tobias a Kreitner, Sandra a Filchtinski, Daniel b Herrmann, Christian b Engel, Daniel a König, Burkhard a Kalbitzer, Hans Robert a

a UNIVERSITY OF REGENSBURG (Germany)

b RUHR UNIVERSITY BOCHUM (Germany)

Author keywords

conformational dynamics; drug design; Ras protein; signal transduction

Indexed keywords

2,2' DIPICOLYLAMINE; 2,2'-DIPICOLYLAMINE; AMINE; COORDINATION COMPOUND; COPPER; PICOLINIC ACID DERIVATIVE; RAS PROTEIN; ZINC;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; METABOLISM; SIGNAL TRANSDUCTION;

AMINES; BINDING SITES; COORDINATION COMPLEXES; COPPER; DRUG DESIGN; MODELS, MOLECULAR; PICOLINIC ACIDS; RAS PROTEINS; SIGNAL TRANSDUCTION; ZINC;

EID: 84867532169 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201204148 Document Type: Article

Times cited : (56)

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