Slow conformational dynamics of the guanine nucleotide-binding protein Ras complexed with the GTP analogue GTPγS

FEBS Journal

Volumn 274, Issue 6, 2007, Pages 1419-1433

  Spoerner, Michael ^a   Nuehs, Andrea ^a   Herrmann, Christian ^b   Steiner, Guido ^a   Kalbitzer, Hans Robert ^a,c  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c Inst F Biophysik Phys Biochem U   (Germany)

Author keywords

Conformational equilibria; GTP analog; GTP S; Ras

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MAGNESIUM ION; MUTANT PROTEIN; RAF PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; CONFORMATION; ENERGY; ENTROPY; HUMAN; ISOTHERMAL TITRATION CALORIMETRY; PREVALENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTON NUCLEAR MAGNETIC RESONANCE; SCALE UP; SPECTROSCOPY; TEMPERATURE DEPENDENCE; TIME; WILD TYPE;

GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HYDROGEN-ION CONCENTRATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; RAS PROTEINS; THERMODYNAMICS;

EID: 33847369890     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.05681.x     Document Type: Article

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