-
1
-
-
0034643268
-
Serum amyloid A is a chemotactic agonist at FPR2, a low-affinity N-formylpeptide receptor on mouse neutrophils
-
Liang, T.S.; Wang, J.M.; Murphy, P.M.; Gao, J.L. Serum amyloid A is a chemotactic agonist at FPR2, a low-affinity N-formylpeptide receptor on mouse neutrophils. Biochem. and Biophys. Res. Comm., 2000, 270, 331-335.
-
(2000)
Biochem. and Biophys. Res. Comm
, vol.270
, pp. 331-335
-
-
Liang, T.S.1
Wang, J.M.2
Murphy, P.M.3
Gao, J.L.4
-
2
-
-
33644882726
-
Signal transduction pathways triggered by selective formylpeptide analogues in human neutrophils
-
Selvatici, R.; Falzarano, S.; Mollica, A.; Spisani, S. Signal transduction pathways triggered by selective formylpeptide analogues in human neutrophils. Eur. J. Pharmacol., 2006, 534, 1-11.
-
(2006)
Eur. J. Pharmacol
, vol.534
, pp. 1-11
-
-
Selvatici, R.1
Falzarano, S.2
Mollica, A.3
Spisani, S.4
-
3
-
-
19744380563
-
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
Nimmerjahn, A.; Kirchhoff, F.; Helmchen, F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science, 2005, 308, 1314-1318.
-
(2005)
Science
, vol.308
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
4
-
-
65249157852
-
Resting Microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals
-
Wake, H.; Moorhouse, A.J.; Jinno, S.; Kohsaka, S.; Nabekura, J. Resting Microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J. Neurosci., 2009, 29, 3974-3980.
-
(2009)
J. Neurosci
, vol.29
, pp. 3974-3980
-
-
Wake, H.1
Moorhouse, A.J.2
Jinno, S.3
Kohsaka, S.4
Nabekura, J.5
-
5
-
-
10644224469
-
Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse
-
Roumier, A.; Bechade, C.; Poncer, J.C.; Smalla, K.H.; Tomasello, E.; Vivier, E.; Gundelfinger, E.D.; Triller, A.; Bessis, A. Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse. J. Neurosci., 2004, 24, 11421-11428.
-
(2004)
J. Neurosci
, vol.24
, pp. 11421-11428
-
-
Roumier, A.1
Bechade, C.2
Poncer, J.C.3
Smalla, K.H.4
Tomasello, E.5
Vivier, E.6
Gundelfinger, E.D.7
Triller, A.8
Bessis, A.9
-
6
-
-
1942447829
-
Microglia promote the death of developing Purkinje cells
-
Marin-Teva, J.L.; Dusart, I.; Colin, C.; Gervais, A.; Van, R.N.; Mallat, M. Microglia promote the death of developing Purkinje cells. Neuron, 2004, 41, 535-547.
-
(2004)
Neuron
, vol.41
, pp. 535-547
-
-
Marin-Teva, J.L.1
Dusart, I.2
Colin, C.3
Gervais, A.4
Van, R.N.5
Mallat, M.6
-
7
-
-
0033659692
-
Novel pathophysiological role of classical chemotactic peptide receptors and their communications with chemokine receptors
-
Le, Y.; Baoqun, Li.; Gong, W.; Shen, W.; Hu, J.; Dunlop, N.M.; Oppenheim, J.J.; Wang, J.M. Novel pathophysiological role of classical chemotactic peptide receptors and their communications with chemokine receptors. Immunol. Rev., 2000, 177, 185-194.
-
(2000)
Immunol. Rev
, vol.177
, pp. 185-194
-
-
Le, Y.1
Baoqun, L.2
Gong, W.3
Shen, W.4
Hu, J.5
Dunlop, N.M.6
Oppenheim, J.J.7
Wang, J.M.8
-
8
-
-
28844487137
-
Cannabinoid receptors in microglia of the central nervous system: Immune functional relevance
-
Cabral, G.A.; Cabral, F.M. Cannabinoid receptors in microglia of the central nervous system: Immune functional relevance. J. of Leuk. Biol., 2005, 78, 1192-1197.
-
(2005)
J. of Leuk. Biol
, vol.78
, pp. 1192-1197
-
-
Cabral, G.A.1
Cabral, F.M.2
-
9
-
-
0348010292
-
Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaqueassociated glia in Alzheimer's disease brains
-
Benito, C.; Nunez, E.; Tolon, R.M.; Carrier, E.J.; Rabano, A.; Hillard, C.J.; Romero, J. Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaqueassociated glia in Alzheimer's disease brains. J. Neurosci., 2003, 23, 11136-11141.
-
(2003)
J. Neurosci
, vol.23
, pp. 11136-11141
-
-
Benito, C.1
Nunez, E.2
Tolon, R.M.3
Carrier, E.J.4
Rabano, A.5
Hillard, C.J.6
Romero, J.7
-
10
-
-
0036001487
-
Isopeptide bonds in chemotactic tripeptides. Synthesis and activity of lysine-containing fMLF analogs
-
Pagani Zecchini, G.; Nalli, M.; Mollica, A.; Lucente, G.; Paglialunga Paradisi, M.; Spisani, S. Isopeptide bonds in chemotactic tripeptides. Synthesis and activity of lysine-containing fMLF analogs. J. Pept. Res., 2002, 59, 283-291.
-
(2002)
J. Pept. Res
, vol.59
, pp. 283-291
-
-
Pagani, Z.G.1
Nalli, M.2
Mollica, A.3
Lucente, G.4
Paglialunga, P.M.5
Spisani, S.6
-
11
-
-
32844469956
-
Chemotactic peptides: FMLF-OMe analogues incorporating proline-methionine chimeras as N-terminal residue
-
Mollica, A.; Paradisi, Paglialunga, M.; Varani, K.; Spisani S.; Lucente, G. Chemotactic peptides: fMLF-OMe analogues incorporating proline-methionine chimeras as N-terminal residue. Bioorg. Med. Chem., 2006, 14, 2253-2265.
-
(2006)
Bioorg. Med. Chem
, vol.14
, pp. 2253-2265
-
-
Mollica, A.1
Paradisi, P.M.2
Varani, K.3
Spisani, S.4
Lucente, G.5
-
12
-
-
33745097975
-
Hybrid α/β-peptides: For-Met-Leu-Phe-OMe analogues containing geminally disubstituted β2,2-and β3,3-amino acids at the central position
-
Mollica, A.; Paglialunga Paradisi, M.; Torino, D.; Spisani, S.; Lucente, G. Hybrid α/β-peptides: For-Met-Leu-Phe-OMe analogues containing geminally disubstituted β2,2-and β3,3-amino acids at the central position. Amino Acids, 2006, 30, 453-459.
-
(2006)
Amino Acids
, vol.30
, pp. 453-459
-
-
Mollica, A.1
Paglialunga, P.M.2
Torino, D.3
Spisani, S.4
Lucente, G.5
-
13
-
-
38149009032
-
Study of synthetic peptides derived from the PKI55 protein, a protein kinase C modulator, in human neutrophils stimulated by the methyl ester derivative of the hydrophobic N-formyl tripeptide for-Met-Leu-Phe-OH
-
Selvatici, R.; Falzarano, S.; Franceschetti, L.; Mollica, A.; Guerrini, R.; Siniscalchi, A.; Spisani, S. Study of synthetic peptides derived from the PKI55 protein, a protein kinase C modulator, in human neutrophils stimulated by the methyl ester derivative of the hydrophobic N-formyl tripeptide for-Met-Leu-Phe-OH. FEBS J., 2008, 275, 449-457.
-
(2008)
FEBS J
, vol.275
, pp. 449-457
-
-
Selvatici, R.1
Falzarano, S.2
Franceschetti, L.3
Mollica, A.4
Guerrini, R.5
Siniscalchi, A.6
Spisani, S.7
-
14
-
-
57749189579
-
Novel chemotactic For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on met residue replacement by 4-amino-proline scaffold
-
Torino, D.; Mollica, A.; Pinnen, F.; Feliciani, F.; Spisani, S.; Lucente, G. Novel chemotactic For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on met residue replacement by 4-amino-proline scaffold: Synthesis and bioactivity. Bioorg. Med. Chem., 2009, 1, 251-259.
-
(2009)
Synthesis and Bioactivity. Bioorg. Med. Chem
, vol.1
, pp. 251-259
-
-
Torino, D.1
Mollica, A.2
Pinnen, F.3
Feliciani, F.4
Spisani, S.5
Lucente, G.6
-
15
-
-
0034814056
-
Microglial chemotaxis, activation, and phagocytosis of amyloid β-peptide as linked phenomena in Alzheimer's disease
-
Rogers, J.; Lue, L.F. Microglial chemotaxis, activation, and phagocytosis of amyloid β-peptide as linked phenomena in Alzheimer's disease. Neurochem. Int., 2001, 39, 333-340.
-
(2001)
Neurochem. Int
, vol.39
, pp. 333-340
-
-
Rogers, J.1
Lue, L.F.2
-
16
-
-
0035864169
-
Amyloid β42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1
-
Le, Y.; Gong, W.; Tiffany, H.L.; Tumanov, A.; Nedospasov, S.; Shen, W.; Dunlop, N.M.; Gao, J.L.; Murphy, P.M.; Oppenheim, J.J.; Wang, J.M. Amyloid β42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1. J. Neurosci., 2001, 21, RC123.
-
(2001)
J. Neurosci
, vol.21
-
-
Le, Y.1
Gong, W.2
Tiffany, H.L.3
Tumanov, A.4
Nedospasov, S.5
Shen, W.6
Dunlop, N.M.7
Gao, J.L.8
Murphy, P.M.9
Oppenheim, J.J.10
Wang, J.M.11
-
17
-
-
4444273069
-
3-peptides with proteinogenic side chains. Monosubstituted analogues of the chemotactic tripeptide For-Met-Leu-Phe-OMe
-
3-peptides with proteinogenic side chains. Monosubstituted analogues of the chemotactic tripeptide For-Met-Leu-Phe-OMe. J Pept. Sci., 2004, 10, 10-23.
-
(2004)
J Pept. Sci
, vol.10
, pp. 10-23
-
-
Giordano, C.1
Lucente, G.2
Mollica, A.3
Nalli, M.4
Pagani, Z.G.5
Paglialunga, P.M.6
Gavuzzo, E.7
Mazza, F.8
Spisani, S.9
-
18
-
-
0029144218
-
β-Amyloid peptide, substance P, and SEC receptor ligand activate cytoplasmic Ca2+ in neutrophil-like HL-60 cells: Effect of chemotactic peptide antagonist BocMLF
-
Takenouchi, T.; Munekata, E. β-Amyloid peptide, substance P, and SEC receptor ligand activate cytoplasmic Ca2+ in neutrophil-like HL-60 cells: Effect of chemotactic peptide antagonist BocMLF. Peptides, 1995, 16, 1019-1024.
-
(1995)
Peptides
, vol.16
, pp. 1019-1024
-
-
Takenouchi, T.1
Munekata, E.2
-
19
-
-
0346366981
-
Differential activation of formyl peptide receptor-like 1 by peptide ligands
-
Bae, Y.S.; Lee, H.Y.; Jo, E.J.; Kim, J.I.; Kang, H.K.; Ye, R.D.; Kwak, J.Y.; Ryu, S.H. Differential activation of formyl peptide receptor-like 1 by peptide ligands. J. Immunol., 2003, 171, 6807-6813.
-
(2003)
J. Immunol
, vol.171
, pp. 6807-6813
-
-
Bae, Y.S.1
Lee, H.Y.2
Jo, E.J.3
Kim, J.I.4
Kang, H.K.5
Ye, R.D.6
Kwak, J.Y.7
Ryu, S.H.8
-
20
-
-
0035968272
-
Amyloid-β induces chemotaxis and oxidant stress by acting at formylpeptide receptor 2, a G proteincoupled receptor expressed in phagocytes and brain
-
Tiffany, H.L.; Lavigne, M.C.; Cui, Y.H.; Wang, J.M.; Leto, T.L.; Gao, J.L.; Murphy, P.M. Amyloid-β induces chemotaxis and oxidant stress by acting at formylpeptide receptor 2, a G proteincoupled receptor expressed in phagocytes and brain. J. Biol. Chem., 2001, 276, 23645-23652.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 23645-23652
-
-
Tiffany, H.L.1
Lavigne, M.C.2
Cui, Y.H.3
Wang, J.M.4
Leto, T.L.5
Gao, J.L.6
Murphy, P.M.7
-
21
-
-
0035158645
-
Amyloid peptide (Aβ42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages
-
Yazawa, H.; Yu, Z.X.; Takeda, K.; Le, Y.; Gong, W.; Ferrans, V.J.; Oppenheim, J.J.; Li, C.C.; Wang, J.M. β Amyloid peptide (Aβ42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages. FASEB J., 2001, 15, 2454-2462.
-
(2001)
FASEB J
, vol.15
, pp. 2454-2462
-
-
Yazawa, H.1
Yu, Z.X.2
Takeda, K.3
Le, Y.4
Gong, W.5
Ferrans, V.J.6
Oppenheim, J.J.7
Li, C.C.8
Wang, J.M.9
-
22
-
-
32344435745
-
Trp-Arg-Trp-Trp-Trp-Trp antagonizes formyl peptide receptor like 2-mediated signaling
-
Shin, E.H.; Lee, H.Y.; Kim, S.D.; Jo, S.H.; Kim, M.K.; Park, K.S.; Lee, H.; Bae, Y.S.; Trp-Arg-Trp-Trp-Trp-Trp antagonizes formyl peptide receptor like 2-mediated signaling. Biochem. Biophys. Res. Comm., 2006, 341, 1317-1322.
-
(2006)
Biochem. Biophys. Res. Comm
, vol.341
, pp. 1317-1322
-
-
Shin, E.H.1
Lee, H.Y.2
Kim, S.D.3
Jo, S.H.4
Kim, M.K.5
Park, K.S.6
Lee, H.7
Bae, Y.S.8
-
23
-
-
23244435384
-
The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met inhibits human monocyte-derived dendritic cell maturation via formyl peptide receptor and formyl peptide receptor-like 2
-
Kang, H.K.; Lee, H.Y.; Kim, M.K.; Park, K.S.; Park, J.M.; Kwak, J.Y.; Bae, Y.S. The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met inhibits human monocyte-derived dendritic cell maturation via formyl peptide receptor and formyl peptide receptor-like 2. J. Immunol., 2005, 175, 685-692.
-
(2005)
J. Immunol
, vol.175
, pp. 685-692
-
-
Kang, H.K.1
Lee, H.Y.2
Kim, M.K.3
Park, K.S.4
Park, J.M.5
Kwak, J.Y.6
Bae, Y.S.7
-
24
-
-
0036744006
-
Human dendritic cells express functional formyl peptide receptor-like-2 (FPRL2) throughout maturation
-
Yang, D.; Chen, Q.; Gertz, B.; He, R.; Phulsuksombati, M.; Ye, R.D.; Oppenheim, J.J. Human dendritic cells express functional formyl peptide receptor-like-2 (FPRL2) throughout maturation. J. Leukoc. Biol., 2002, 72, 598-607.
-
(2002)
J. Leukoc. Biol
, vol.72
, pp. 598-607
-
-
Yang, D.1
Chen, Q.2
Gertz, B.3
He, R.4
Phulsuksombati, M.5
Ye, R.D.6
Oppenheim, J.J.7
-
25
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau, J.; Steinman, R.M. Dendritic cells and the control of immunity. Nature, 1998, 392, 245-252.
-
(1998)
Nature
, vol.392
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
26
-
-
51449099473
-
Synuclein activates microglia in a model of Parkinson's disease
-
Su, X.; Maguire-Zeiss, K.A.; Giuliano, R.; Prifti, L.; Venkatesh, K.; Federhoff, H.J. Synuclein activates microglia in a model of Parkinson's disease. Neurobiol. Aging, 2007, 29, 1690-1701.
-
(2007)
Neurobiol. Aging
, vol.29
, pp. 1690-1701
-
-
Su, X.1
Maguire-Zeiss, K.A.2
Giuliano, R.3
Prifti, L.4
Venkatesh, K.5
Federhoff, H.J.6
-
27
-
-
77955090344
-
Tickets to the brain: Role of CCR2 and CX(3)CR1in myeloid cell entry in the CNS
-
Prinz, M.; Priller, J. Tickets to the brain: Role of CCR2 and CX(3)CR1in myeloid cell entry in the CNS. J. Neuroimmunol., 2010, 224, 80-84.
-
(2010)
J. Neuroimmunol
, vol.224
, pp. 80-84
-
-
Prinz, M.1
Priller, J.2
-
28
-
-
0023789193
-
Reactive microglia are positive for HLAβDR in the substantia nigra of Parkinson's and Alzheimer's disease brains
-
McGeer, P.L.; Itagaki, S.; Boyes, B.E.; McGeer, E.G. Reactive microglia are positive for HLAβDR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology, 1988, 38, 1285-1291.
-
(1988)
Neurology
, vol.38
, pp. 1285-1291
-
-
McGeer, P.L.1
Itagaki, S.2
Boyes, B.E.3
McGeer, E.G.4
-
29
-
-
0032710609
-
Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
-
Liberatore, G.T.; Jackson-Lewis, V.; Vukosavic, S.; Mandir, A.S.; Vila, M.; McAuliffe, W.G.; Dawson, V.L.; Dawson, T.M.; Przedborski, S. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nat. Med., 1999, 5, 1403-1409.
-
(1999)
Nat. Med
, vol.5
, pp. 1403-1409
-
-
Liberatore, G.T.1
Jackson-Lewis, V.2
Vukosavic, S.3
Mandir, A.S.4
Vila, M.5
McAuliffe, W.G.6
Dawson, V.L.7
Dawson, T.M.8
Przedborski, S.9
-
30
-
-
0037947448
-
NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
-
Wu, D.C.; Teismann, P.; Tieu, K.; Vila, M.; Jackson-Lewis, V.; Ischiropoulos, H.; Przedborski, S. NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. Proc. Natl. Acad. Sci. USA, 2003, 100, 6145-6150.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6145-6150
-
-
Wu, D.C.1
Teismann, P.2
Tieu, K.3
Vila, M.4
Jackson-Lewis, V.5
Ischiropoulos, H.6
Przedborski, S.7
-
31
-
-
65249089638
-
In vivo analysis of dendritic cell development and homeostasis
-
Liu, K.; Victora, G.D.; Schwickert, T.A.; Guermonprez, P.; Meredith, M.M.; Yao, K.; Chu, F.F.; Randolph, G.J.; Rudensky, A.Y.; Nussenzweig, M. In vivo analysis of dendritic cell development and homeostasis. Science, 2009, 324, 392-397.
-
(2009)
Science
, vol.324
, pp. 392-397
-
-
Liu, K.1
Victora, G.D.2
Schwickert, T.A.3
Guermonprez, P.4
Meredith, M.M.5
Yao, K.6
Chu, F.F.7
Randolph, G.J.8
Rudensky, A.Y.9
Nussenzweig, M.10
-
32
-
-
58849107919
-
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
-
Brochard V, Combadiere B, Prigent A, Laouar Y, Perrin A, Beray-Berthat V, Bonduelle O, Alvarez-Fischer D, Callebert J, Launay JM, Duyckaerts C, Flavell RA, Hirsch EC, Hunot S. Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. J. Clin. Invest., 2009, 119, 182-192.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 182-192
-
-
Brochard, V.1
Combadiere, B.2
Prigent, A.3
Laouar, Y.4
Perrin, A.5
Beray-Berthat, V.6
Bonduelle, O.7
Alvarez-Fischer, D.8
Callebert, J.9
Launay, J.M.10
Duyckaerts, C.11
Flavell, R.A.12
Hirsch, E.C.13
Hunot, S.14
-
33
-
-
34548822734
-
The role of anti-inflammatory agents in Parkinson's disease
-
McGeer, E.G.; McGeer, P.L. The role of anti-inflammatory agents in Parkinson's disease. CNS Drugs, 2007, 21,789-797.
-
(2007)
CNS Drugs
, vol.21
, pp. 789-797
-
-
McGeer, E.G.1
McGeer, P.L.2
-
34
-
-
0041653249
-
Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease
-
Chen, H., Zhang, S.M., Hernán, M.A., Schwarzschild, M.A., Willett, W.C., Colditz, G.A., Speizer, F.E., Ascherio, A. Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease Arch. Neurol., 2003, 60, 1065-1073.
-
(2003)
Arch. Neurol
, vol.60
, pp. 1065-1073
-
-
Chen, H.1
Zhang, S.M.2
Hernán, M.A.3
Schwarzschild, M.A.4
Willett, W.C.5
Colditz, G.A.6
Speizer, F.E.7
Ascherio, A.8
-
35
-
-
28544451467
-
Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease
-
Chen, H.; Jacobs, E.; Schwarzschild, M.A.; McCullough, M.L.; Calle, E.E.; Thun, M.J.; Ascherio, A. Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease. Ann. Neurol., 2005, 58, 963-967.
-
(2005)
Ann. Neurol
, vol.58
, pp. 963-967
-
-
Chen, H.1
Jacobs, E.2
Schwarzschild, M.A.3
McCullough, M.L.4
Calle, E.E.5
Thun, M.J.6
Ascherio, A.7
-
36
-
-
34147115541
-
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
-
El Khoury, J.; Toft, M.; Hickman, S.E.; Means, T.K.; Terada, K.; Geula, C.; Luster, A.D. Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat. Med., 2007, 13, 432-438.
-
(2007)
Nat. Med
, vol.13
, pp. 432-438
-
-
El, K.J.1
Toft, M.2
Hickman, S.E.3
Means, T.K.4
Terada, K.5
Geula, C.6
Luster, A.D.7
-
37
-
-
36448955070
-
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions
-
Mildner, A.; Schmidt, H.; Nitsche, M.; Merkler, D.; Hanisch, U.K.; Mack, M.; Heikenwalder, M.; Bruck, W.; Priller, J.; Prinz, M. Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat. Neurosci., 2007, 10, 1544-1553.
-
(2007)
Nat. Neurosci
, vol.10
, pp. 1544-1553
-
-
Mildner, A.1
Schmidt, H.2
Nitsche, M.3
Merkler, D.4
Hanisch, U.K.5
Mack, M.6
Heikenwalder, M.7
Bruck, W.8
Priller, J.9
Prinz, M.10
-
38
-
-
33845980539
-
Chemokines in the MPTP model of Parkinson's disease: Absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration
-
Kalkonde, Y.V.; Morgan, W.W.; Sigala, J.; Maffi, S.K.; Condello, C.; Kuziel, W.; Ahuja, S.S.; Ahuja, S.K. Chemokines in the MPTP model of Parkinson's disease: Absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration. Brain Res., 2007, 1128, 1-11.
-
(2007)
Brain Res
, vol.1128
, pp. 1-11
-
-
Kalkonde, Y.V.1
Morgan, W.W.2
Sigala, J.3
Maffi, S.K.4
Condello, C.5
Kuziel, W.6
Ahuja, S.S.7
Ahuja, S.K.8
-
39
-
-
29144445369
-
Multiple opioid receptors on immune cells modulate intracellular signaling
-
Sharp, B.M. Multiple opioid receptors on immune cells modulate intracellular signaling. Brain Behav. Immun., 2006, 20, 9-14.
-
(2006)
Brain Behav. Immun
, vol.20
, pp. 9-14
-
-
Sharp, B.M.1
-
40
-
-
1242314192
-
Effects of the combined treatment of naloxone and indomethacin on catecholamines and behavior after intranigral lipopolysaccharide injection
-
Wang, V.; Chia, L.G.; Ni, D.R.; Cheng, L.J.; Ho, Y.P.; Cheng, F.C.; Hong, J.S. Effects of the combined treatment of naloxone and indomethacin on catecholamines and behavior after intranigral lipopolysaccharide injection. Neurochem. Res., 2004, 29, 341-346.
-
(2004)
Neurochem. Res
, vol.29
, pp. 341-346
-
-
Wang, V.1
Chia, L.G.2
Ni, D.R.3
Cheng, L.J.4
Ho, Y.P.5
Cheng, F.C.6
Hong, J.S.7
-
41
-
-
0036721255
-
Inhibition by naloxone stereoisomers of β-amyloid peptide(1-42)-induced superoxide production in microglia and degeneration of cortical and mesencephalic neurons
-
Liu, Y.; Qin, L.; Wilson, B.C.; An, L.; Hong, J.S. Inhibition by naloxone stereoisomers of β-amyloid peptide(1-42)-induced superoxide production in microglia and degeneration of cortical and mesencephalic neurons. J. Pharmacol. Exp. Ther., 2002, 302, 1212-1219.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.302
, pp. 1212-1219
-
-
Liu, Y.1
Qin, L.2
Wilson, B.C.3
An, L.4
Hong, J.S.5
-
42
-
-
0037381043
-
Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation
-
Liu, Y.; Qin, L.; Li, G.; Zhang, W.; An, L.; Liu, B.; Hong, J.S. Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation. J. Pharmacol. Exp. Ther., 2003, 305, 212-218.
-
(2003)
J. Pharmacol. Exp. Ther
, vol.305
, pp. 212-218
-
-
Liu, Y.1
Qin, L.2
Li, G.3
Zhang, W.4
An, L.5
Liu, B.6
Hong, J.S.7
-
43
-
-
0038327644
-
Dextromethorphan prevents the diethyldithiocarbamate enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in mice
-
Vaglini, F.; Pardini, C.; Bonuccelli, U.; Maggio, R.; Corsini, G.U. Dextromethorphan prevents the diethyldithiocarbamate enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in mice. Brain Res., 2003, 973, 298-302.
-
(2003)
Brain Res
, vol.973
, pp. 298-302
-
-
Vaglini, F.1
Pardini, C.2
Bonuccelli, U.3
Maggio, R.4
Corsini, G.U.5
-
44
-
-
33750478657
-
Wild-type microglia extend survival in PU.1 knockoutmice with familial amyotrophic lateral sclerosis
-
Beers, D.R.; Henkel, J.S.; Xiao, Q.; Zhao, W.; Wang, J.; Yen, A.A.; Siklos, L.; McKercher, S.R.; Appel, S.H. Wild-type microglia extend survival in PU.1 knockoutmice with familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA, 2006, 103, 16021-16026.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 16021-16026
-
-
Beers, D.R.1
Henkel, J.S.2
Xiao, Q.3
Zhao, W.4
Wang, J.5
Yen, A.A.6
Siklos, L.7
McKercher, S.R.8
Appel, S.H.9
-
45
-
-
33749056809
-
ALS: A disease of motor neurons and their non-neuronal neighbors
-
Boillee, S.; Vande, V.C.; Cleveland, D.W. ALS: A disease of motor neurons and their non-neuronal neighbors. Neuron, 2006, 52, 39-59.
-
(2006)
Neuron
, vol.52
, pp. 39-59
-
-
Boillee, S.1
Vande, V.C.2
Cleveland, D.W.3
-
46
-
-
44949215794
-
Genetic studies of GRN and IFT74 in amyotrophic lateral sclerosis
-
Xiao, S.; Sato, C.; Kawarai, T.; Goodall, E.F.; Pall, H.S.; Zinman, L.H.; Robertson, J.; Morrison, K.; Rogaeva, E. Genetic studies of GRN and IFT74 in amyotrophic lateral sclerosis. Neurobiol. Aging, 2008, 29, 1279-1282.
-
(2008)
Neurobiol. Aging
, vol.29
, pp. 1279-1282
-
-
Xiao, S.1
Sato, C.2
Kawarai, T.3
Goodall, E.F.4
Pall, H.S.5
Zinman, L.H.6
Robertson, J.7
Morrison, K.8
Rogaeva, E.9
-
47
-
-
71549119504
-
Macrophage colony stimulating factor (M-CSF) exacerbates ALS disease in a mouse model through altered responses of microglia expressing mutant superoxide dismutase
-
Gowing, G.; Lalancette-Hebert, M.; Audet, J.N.; Dequen, F.; Julien, J.P. Macrophage colony stimulating factor (M-CSF) exacerbates ALS disease in a mouse model through altered responses of microglia expressing mutant superoxide dismutase Exp. Neurol., 2009, 220, 267-275.
-
(2009)
Exp. Neurol
, vol.220
, pp. 267-275
-
-
Gowing, G.1
Lalancette-Hebert, M.2
Audet, J.N.3
Dequen, F.4
Julien, J.P.5
-
48
-
-
33646250429
-
Origin and distribution of bone marrow-derived cells in the central nervous system in a mouse model of amyotrophic lateral sclerosis
-
Solomon, J.N.; Lewis, C.A.; Ajami, B.; Corbel, S.Y.; Rossi, F.M.; Krieger, C. Origin and distribution of bone marrow-derived cells in the central nervous system in a mouse model of amyotrophic lateral sclerosis. Glia, 2006, 53, 744-753.
-
(2006)
Glia
, vol.53
, pp. 744-753
-
-
Solomon, J.N.1
Lewis, C.A.2
Ajami, B.3
Corbel, S.Y.4
Rossi, F.M.5
Krieger, C.6
-
49
-
-
55449090370
-
Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis
-
Appel, S.H.; Engelhardt, J.I.; Henkel, J.S.; Siklos, L.; Beers, D.R.; Yen, A.A.; Simpson, E.P.; Luo, Y.; Carrum, G.; Heslop, H.E.; Brenner, M.K.; Popat, U. Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis. Neurology, 2008, 71, 1326-1334.
-
(2008)
Neurology
, vol.71
, pp. 1326-1334
-
-
Appel, S.H.1
Engelhardt, J.I.2
Henkel, J.S.3
Siklos, L.4
Beers, D.R.5
Yen, A.A.6
Simpson, E.P.7
Luo, Y.8
Carrum, G.9
Heslop, H.E.10
Brenner, M.K.11
Popat, U.12
-
50
-
-
36448994709
-
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
-
Ajami, B.; Bennett, J.L.; Krieger, C.; Tetzlaff, W.; Rossi, F.M. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat. Neurosci., 2007, 10, 1538-1543.
-
(2007)
Nat. Neurosci
, vol.10
, pp. 1538-1543
-
-
Ajami, B.1
Bennett, J.L.2
Krieger, C.3
Tetzlaff, W.4
Rossi, F.M.5
-
51
-
-
35448962057
-
MKK6 phosphorylation regulates production of superoxide by enhancing Rac GTPase activity
-
Harraz, M.M.; Park, A.; Abbott, D.; Zhou, W.; Zhang, Y.; Engelhardt, J.F. MKK6 phosphorylation regulates production of superoxide by enhancing Rac GTPase activity. Antioxid. Redox Signal., 2007, 9, 1803-1813.
-
(2007)
Antioxid. Redox Signal
, vol.9
, pp. 1803-1813
-
-
Harraz, M.M.1
Park, A.2
Abbott, D.3
Zhou, W.4
Zhang, Y.5
Engelhardt, J.F.6
-
52
-
-
38849182472
-
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model
-
Harraz, M.M.; Marden, J.J.; Zhou, W.; Zhang, Y.; Williams, A.; Sharov, V.S.; Nelson, K.; Luo, M.; Paulson, H.; Schöneich, C.; Engelhardt, J.F. SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model. J. Clin. Invest., 2008, 118, 659-670.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 659-670
-
-
Harraz, M.M.1
Marden, J.J.2
Zhou, W.3
Zhang, Y.4
Williams, A.5
Sharov, V.S.6
Nelson, K.7
Luo, M.8
Paulson, H.9
Schöneich, C.10
Engelhardt, J.F.11
-
53
-
-
80755168115
-
Mini-symposium: The role of microglia in the healthy brain
-
Tremblay, M.E.; Stevens, B.; Sierra, A.; Wake, H.; Bessis, A.; Nimmerjahn, A. Mini-symposium: The role of microglia in the healthy brain. J. Neurosci., 2011, 31, 16064-16069.
-
(2011)
J. Neurosci
, vol.31
, pp. 16064-16069
-
-
Tremblay, M.E.1
Stevens, B.2
Sierra, A.3
Wake, H.4
Bessis, A.5
Nimmerjahn, A.6
-
54
-
-
70449732762
-
The proinflammatory action of microglial P2 receptors is enhanced in SOD1 models for amyotrophic lateral sclerosis
-
D'Ambrosi, N.; Finocchi, P.; Apolloni, S.; Cozzolino, M.; Ferri, A.; Padovano, V.; Pietrini, G.; Carrì, M.T.; Volonté, C. The proinflammatory action of microglial P2 receptors is enhanced in SOD1 models for amyotrophic lateral sclerosis. J. Immunol., 2009, 183, 4648-4656.
-
(2009)
J. Immunol
, vol.183
, pp. 4648-4656
-
-
D'Ambrosi, N.1
Finocchi, P.2
Apolloni, S.3
Cozzolino, M.4
Ferri, A.5
Padovano, V.6
Pietrini, G.7
Carrì, M.T.8
Volonté, C.9
-
55
-
-
0029085515
-
Neuronal cell death in scrapie-infected mice is due to apoptosis
-
Giese, A.; Groschoup, M.H.; Hess, B.; Kretzschmar, H.A. Neuronal cell death in scrapie-infected mice is due to apoptosis. Brain Pathol., 1995, 5, 213-221.
-
(1995)
Brain Pathol
, vol.5
, pp. 213-221
-
-
Giese, A.1
Groschoup, M.H.2
Hess, B.3
Kretzschmar, H.A.4
-
56
-
-
0025270288
-
The mRNA encoding the scrapie agent protein is present in a variety of non-neuronal cells
-
Brown, D.R.; Goller, N.L.; Rudelli, R.D.; Merz, G.S.; Wolfe, G.C.; Wisniewski, H.M.; Robakis, N.K. The mRNA encoding the scrapie agent protein is present in a variety of non-neuronal cells. Acta Neuropathol., 1990, 80, 1-6.
-
(1990)
Acta Neuropathol
, vol.80
, pp. 1-6
-
-
Brown, D.R.1
Goller, N.L.2
Rudelli, R.D.3
Merz, G.S.4
Wolfe, G.C.5
Wisniewski, H.M.6
Robakis, N.K.7
-
58
-
-
0031859927
-
The priori diseases
-
Prusiner, S.B. The priori diseases. Brain Pathol., 1998, 8, 499-513.
-
(1998)
Brain Pathol
, vol.8
, pp. 499-513
-
-
Prusiner, S.B.1
-
60
-
-
0035253564
-
The neurotoxic prion peptide fragment PrP (106-126) is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1
-
Le, Y.; Yazawa, H.; Gong, W.; Yu, Z.; Ferrans, V.J.; Murphy, P.M.; Wang, J.M. The neurotoxic prion peptide fragment PrP (106-126) is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1. J. Immunol., 2001, 166, 1448-1451.
-
(2001)
J. Immunol
, vol.166
, pp. 1448-1451
-
-
Le, Y.1
Yazawa, H.2
Gong, W.3
Yu, Z.4
Ferrans, V.J.5
Murphy, P.M.6
Wang, J.M.7
-
61
-
-
0024853737
-
Ferritin immunohistochemistry as a marker for microglia
-
Kaneko, Y.; Kitamoto, T.; Tateishi, J.; Yamaguchi, K. Ferritin immunohistochemistry as a marker for microglia. Acta Neuropathol., 1989, 79, 129-136.
-
(1989)
Acta Neuropathol
, vol.79
, pp. 129-136
-
-
Kaneko, Y.1
Kitamoto, T.2
Tateishi, J.3
Yamaguchi, K.4
-
62
-
-
0028220907
-
Relationship of microglia and scrapie amyloid-immunoreactive plaques in kuru, Creutzfeldt-Jakob disease and Gerstmann-Sträußler syndrome
-
Guiroy, D.C.; Wakayama, I.; Liberski, P.P.; Gaydusek, D.C. Relationship of microglia and scrapie amyloid-immunoreactive plaques in kuru, Creutzfeldt-Jakob disease and Gerstmann-Sträußler syndrome. Acta Neuropathol., 1994, 87, 526-530.
-
(1994)
Acta Neuropathol
, vol.87
, pp. 526-530
-
-
Guiroy, D.C.1
Wakayama, I.2
Liberski, P.P.3
Gaydusek, D.C.4
-
63
-
-
0018167098
-
Studies of the lymphoreticular system in the pathogenesis of scrapie: The role of spleen and thymus
-
Fraser, H.; Dickinson, A.G. Studies of the lymphoreticular system in the pathogenesis of scrapie: The role of spleen and thymus. J. Comp. Pathol., 1978, 88, 563-573.
-
(1978)
J. Comp. Pathol
, vol.88
, pp. 563-573
-
-
Fraser, H.1
Dickinson, A.G.2
-
64
-
-
0017871609
-
Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease). The nature and progression of spongiform change
-
Masters, C.L.; Richardson, E.P. Jr. Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease). The nature and progression of spongiform change. Brain, 1978, 101, 333-344.
-
(1978)
Brain
, vol.101
, pp. 333-344
-
-
Masters, C.L.1
Richardson Jr., E.P.2
-
65
-
-
0032507653
-
Microglial expression of the prion protein
-
Brown, D.R.; Besinger, A.; Herms, J.W.; Kretzschmar, H.A. Microglial expression of the prion protein. Neuroreport, 1998, 9, 1425-1429.
-
(1998)
Neuroreport
, vol.9
, pp. 1425-1429
-
-
Brown, D.R.1
Besinger, A.2
Herms, J.W.3
Kretzschmar, H.A.4
-
66
-
-
0033083722
-
Astrocytic glutamate uptake and prion protein expression
-
Brown, D.R.; Mohn, C.M. Astrocytic glutamate uptake and prion protein expression. Glia, 1999, 25, 282-292.
-
(1999)
Glia
, vol.25
, pp. 282-292
-
-
Brown, D.R.1
Mohn, C.M.2
-
67
-
-
0027257829
-
Microglia is a component of the prion protein amyloid plaque in the Gerstmann-Sträussler-Scheinker syndrome
-
Barcikowska, M.; Liberski, P.P.; Boellaard, J.W.; Brown, P.; Gaydusek, D.C.; Budka, H. Microglia is a component of the prion protein amyloid plaque in the Gerstmann-Sträussler-Scheinker syndrome. Acta Neuropathol., 1993, 85, 623-627.
-
(1993)
Acta Neuropathol
, vol.85
, pp. 623-627
-
-
Barcikowska, M.1
Liberski, P.P.2
Boellaard, J.W.3
Brown, P.4
Gaydusek, D.C.5
Budka, H.6
-
68
-
-
0031942743
-
Microglia and the development of spongiform change in Creutzfeldt-Jakob disease
-
Eitzen, U.; Egensperger, R.; Kösel, S.; Grasbon-Frodl, E.M.; Imai, Y.; Bise, K.; Kohsaka, S.; Mehraein, P.; Graeber, M.B. Microglia and the development of spongiform change in Creutzfeldt-Jakob disease. J. Neuropathol. Exp. Neurol., 1998, 57, 246-256.
-
(1998)
J. Neuropathol. Exp. Neurol
, vol.57
, pp. 246-256
-
-
Eitzen, U.1
Egensperger, R.2
Kösel, S.3
Grasbon-Frodl, E.M.4
Imai, Y.5
Bise, K.6
Kohsaka, S.7
Mehraein, P.8
Graeber, M.B.9
-
69
-
-
0031778574
-
Central neuron-glial and glialglial interactions following axon injury
-
Aldskogius, H.; Kozlova, E.N. Central neuron-glial and glialglial interactions following axon injury. Prog. Neurobiol., 1998, 55, 1-26.
-
(1998)
Prog. Neurobiol
, vol.55
, pp. 1-26
-
-
Aldskogius, H.1
Kozlova, E.N.2
-
70
-
-
0028847204
-
Differential macrophage responses in the peripheral and central nervous system during Wallerian degeneration of axons
-
Avellino, A.M.; Hart, D.; Dailey, A.T.; MacKinnon, M.; Ellegala, D.; Kliot, M. Differential macrophage responses in the peripheral and central nervous system during Wallerian degeneration of axons. Exp. Neurol., 1995, 136, 183-198.
-
(1995)
Exp. Neurol
, vol.136
, pp. 183-198
-
-
Avellino, A.M.1
Hart, D.2
Dailey, A.T.3
Mackinnon, M.4
Ellegala, D.5
Kliot, M.6
-
71
-
-
0033961320
-
Chemokines and their receptors in neurobiology: Perspectives in physiology and homeostasis
-
Bacon, K.B.; Harrison, J.K. Chemokines and their receptors in neurobiology: Perspectives in physiology and homeostasis. J. Neuroimmunol., 2000, 104, 92-97.
-
(2000)
J. Neuroimmunol
, vol.104
, pp. 92-97
-
-
Bacon, K.B.1
Harrison, J.K.2
-
72
-
-
0028006787
-
Inflammation and axonal regeneration
-
Richardson, P.M.; Lu, X. Inflammation and axonal regeneration. J. Neurol., 1994, 242, S57-S60.
-
(1994)
J. Neurol
, vol.242
-
-
Richardson, P.M.1
Lu, X.2
-
73
-
-
0032210917
-
Peripheral nerve-stimulated macrophages simulate a peripheral nerve-like regenerative response in rat transected optic nerve
-
Lazarov-Spiegler, O.; Solomon, A.S.; Schwartz, M. Peripheral nerve-stimulated macrophages simulate a peripheral nerve-like regenerative response in rat transected optic nerve. Glia, 1998, 24, 329-337.
-
(1998)
Glia
, vol.24
, pp. 329-337
-
-
Lazarov-Spiegler, O.1
Solomon, A.S.2
Schwartz, M.3
-
74
-
-
0029834320
-
Transplantation of activated macrophages overcomes central nervous system regrowth failure
-
Lazarov-Spiegler, O.; Soloman, A.S.; Zeev-Brann, A.B.; Hirschberg, D.L.; Lavie, V.; Schwartz, M. Transplantation of activated macrophages overcomes central nervous system regrowth failure. FASEB J., 1996, 10, 1296-1302.
-
(1996)
FASEB J
, vol.10
, pp. 1296-1302
-
-
Lazarov-Spiegler, O.1
Soloman, A.S.2
Zeev-Brann, A.B.3
Hirschberg, D.L.4
Lavie, V.5
Schwartz, M.6
-
75
-
-
0032322025
-
Temporary colonization of the site of lesion by macrophages is a prelude to the arrival of regenerated axons in injured goldfish optic nerve
-
Nona, S.N.; Thomlinson, A.M.; Stafford, C.A. Temporary colonization of the site of lesion by macrophages is a prelude to the arrival of regenerated axons in injured goldfish optic nerve. J. Neurocytol., 1998, 27, 791-803.
-
(1998)
J. Neurocytol
, vol.27
, pp. 791-803
-
-
Nona, S.N.1
Thomlinson, A.M.2
Stafford, C.A.3
-
76
-
-
34547380204
-
Neuroinflammation in Alzheimer's disease and Parkinson's disease: Are microglia pathogenic in either disorder?
-
Rogers, J.; Mastroeni, D.; Leonard, B.; Joyce, J.; Grover, A. Neuroinflammation in Alzheimer's disease and Parkinson's disease: Are microglia pathogenic in either disorder? Int. Rev. Neurobiol., 2007, 82, 235-246.
-
(2007)
Int. Rev. Neurobiol
, vol.82
, pp. 235-246
-
-
Rogers, J.1
Mastroeni, D.2
Leonard, B.3
Joyce, J.4
Grover, A.5
-
77
-
-
84858259145
-
Clearance of amyloid-β peptides by microglia and macrophages: The issue of what, when and where
-
Lai, A.Y.; McLaurin, J. Clearance of amyloid-β peptides by microglia and macrophages: The issue of what, when and where. Future Neurol., 2012, 7, 165-176.
-
(2012)
Future Neurol
, vol.7
, pp. 165-176
-
-
Lai, A.Y.1
McLaurin, J.2
-
78
-
-
69949118284
-
Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease
-
Streit, W.J.; Braak, H.; Xue, Q.S.; Bechmann, I. Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease. Acta Neuropathol., 2009, 118, 475-485.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 475-485
-
-
Streit, W.J.1
Braak, H.2
Xue, Q.S.3
Bechmann, I.4
-
79
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk, D.; Barbour, R.; Dunn, W.; Gordon, G.; Grajeda, H.; Guido, T.; Hu, K.; Huang, J.; Johnson-Wood, K.; Khan, K.; Kholodenko, D.; Lee, M.; Liao, Z.; Lieberburg, I.; Motter, R.; Mutter, L.; Soriano, F.; Shopp, G.; Vasquez, N.; Vandevert, C.; Walker, S.; Wogulis, M.; Yednock, T.; Games, D.; Seubert, P. Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature, 1999, 400, 173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
80
-
-
0037203825
-
Nerve inflammation halts trial for Alzheimer's drug
-
Check, E. Nerve inflammation halts trial for Alzheimer's drug. Nature, 2002, 415, 462.
-
(2002)
Nature
, vol.415
, pp. 462
-
-
Check, E.1
-
81
-
-
47149112621
-
Long-term effects of Aβ42 immunisation in Alzheimer's disease: Follow-up of a randomised, placebocontrolled phase I trial
-
Holmes, C.; Boche, D.; Wilkinson, D.; Yadegarfar, G.; Hopkins, V.; Bayer, A.; Jones, R.W.; Bullock, R.; Love, S.; Neal, J.W.; Zotova, E.; Nicoll, J.A. Long-term effects of Aβ42 immunisation in Alzheimer's disease: Follow-up of a randomised, placebocontrolled phase I trial. Lancet, 2008, 372, 216-223.
-
(2008)
Lancet
, vol.372
, pp. 216-223
-
-
Holmes, C.1
Boche, D.2
Wilkinson, D.3
Yadegarfar, G.4
Hopkins, V.5
Bayer, A.6
Jones, R.W.7
Bullock, R.8
Love, S.9
Neal, J.W.10
Zotova, E.11
Nicoll, J.A.12
-
82
-
-
65249119363
-
Powerful beneficial effects of macrophage colonystimulating factor on β-amyloid deposition and cognitive impairment in Alzheimer's disease
-
Boissonneault, V.; Filali, M.; Lessard, M.; Relton, J.; Wong, G.; Rivest, S. Powerful beneficial effects of macrophage colonystimulating factor on β-amyloid deposition and cognitive impairment in Alzheimer's disease. Brain, 2009, 132, 1078-1092.
-
(2009)
Brain
, vol.132
, pp. 1078-1092
-
-
Boissonneault, V.1
Filali, M.2
Lessard, M.3
Relton, J.4
Wong, G.5
Rivest, S.6
-
83
-
-
68349127365
-
Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice
-
Sanchez-Ramos, J.; Song, S.; Sava, V.; Catlow, B.; Lin, X.; Mori, T.; Cao, C.; Arendash, G.W. Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice. Neurosci., 2009, 163, 55-72.
-
(2009)
Neurosci
, vol.163
, pp. 55-72
-
-
Sanchez-Ramos, J.1
Song, S.2
Sava, V.3
Catlow, B.4
Lin, X.5
Mori, T.6
Cao, C.7
Arendash, G.W.8
-
84
-
-
74949127437
-
Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia
-
Grathwohl, S.A.; Kalin, R.E.; Bolmont, T.; Prokop, S.; Winkelmann, G.; Kaeser, S.A.: Odenthal, J.; Radde, R.; Eldh, T.; Gandy, S.; Aguzzi, A.; Staufenbiel, M.; Mathews, P.M.; Wolburg, H.; Heppner, F.L.; Jucker, M. Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia. Nat. Neurosci., 2009, 12, 1361-1363.
-
(2009)
Nat. Neurosci
, vol.12
, pp. 1361-1363
-
-
Grathwohl, S.A.1
Kalin, R.E.2
Bolmont, T.3
Prokop, S.4
Winkelmann, G.5
Kaeser, S.A.6
Odenthal, J.7
Radde, R.8
Eldh, T.9
Gandy, S.10
Aguzzi, A.11
Staufenbiel, M.12
Mathews, P.M.13
Wolburg, H.14
Heppner, F.L.15
Jucker, M.16
-
85
-
-
0035691115
-
Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice
-
Lim, G.P.; Yang, F.; Chu, T.; Gahtan, E.; Ubeda, O.; Beech, W.; Overmier, J.B.; Hsiao-Ashec, K.; Frautschy, S.A.; Cole, G.M. Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice. Neurobiol. Aging, 2001, 22, 983-991.
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 983-991
-
-
Lim, G.P.1
Yang, F.2
Chu, T.3
Gahtan, E.4
Ubeda, O.5
Beech, W.6
Overmier, J.B.7
Hsiao-Ashec, K.8
Frautschy, S.A.9
Cole, G.M.10
-
86
-
-
0034808079
-
Ligand modulation of glial activation: Cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1β and nitric oxide synthase II
-
Watterson, D.M.; Mirzoeva, S.; Guo, L.; Whyte, A.; Bourguignon, J.J.; Hibert, M.; Haiech, J.; Van Eldik, L.J. Ligand modulation of glial activation: Cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1β and nitric oxide synthase II. Neurochem. Int., 2001, 39, 459-468.
-
(2001)
Neurochem. Int
, vol.39
, pp. 459-468
-
-
Watterson, D.M.1
Mirzoeva, S.2
Guo, L.3
Whyte, A.4
Bourguignon, J.J.5
Hibert, M.6
Haiech, J.7
van Eldik, L.J.8
-
87
-
-
4644316149
-
Aminopyridazines inhibit β-amyloid-induced glial activation and neuronal damage in vivo
-
Craft, J.M.; Watterson, D.M.; Frautschy, S.A.; Van Eldik, L. Aminopyridazines inhibit β-amyloid-induced glial activation and neuronal damage in vivo. J. Neurobiol. Aging, 2004, 25, 1283-1292.
-
(2004)
J. Neurobiol. Aging
, vol.25
, pp. 1283-1292
-
-
Craft, J.M.1
Watterson, D.M.2
Frautschy, S.A.3
Eldik, V.L.4
-
88
-
-
0035686083
-
Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology
-
Frautschy, S.A.; Hu, W.; Kim, P.; Miller, S.A.; Chu, T.; Harris-White, M.E.; Cole, G.M. Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology. J. Neurobiol. Aging, 2001, 22, 993-1005.
-
(2001)
J. Neurobiol. Aging
, vol.22
, pp. 993-1005
-
-
Frautschy, S.A.1
Hu, W.2
Kim, P.3
Miller, S.A.4
Chu, T.5
Harris-White, M.E.6
Cole, G.M.7
-
89
-
-
65349097903
-
Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes
-
Young, S.M.; Bologa, C.M.; Fara, D.; Bryant, B.K.; Strouse, J.J.; Arterburn, J.B.; Ye, R.D.; Oprea, T.I.; Prossnitz, E.R.; Sklar, L.A.; Edwards, B.S. Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes. Cytometry A., 2009, 75, 253-263.
-
(2009)
Cytometry A
, vol.75
, pp. 253-263
-
-
Young, S.M.1
Bologa, C.M.2
Fara, D.3
Bryant, B.K.4
Strouse, J.J.5
Arterburn, J.B.6
Ye, R.D.7
Oprea, T.I.8
Prossnitz, E.R.9
Sklar, L.A.10
Edwards, B.S.11
-
90
-
-
69049103120
-
6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: A novel class of small-molecule agonists for formyl peptide receptors
-
Cilibrizzi, A.; Quinn, M.T.; Kirpotina, L.N.; Schepetkin, I.A.; Holderness, J.; Ye, R.D.; Rabiet, M.J.; Biancalani, C.; Cesari, N.; Graziano, A.; Vergelli, C.; Pieretti, S.; Dal Piaz, V.; Giovannoni, M.P. 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: A novel class of small-molecule agonists for formyl peptide receptors. J. Med. Chem., 2009, 52, 5044-5057.
-
(2009)
J. Med. Chem
, vol.52
, pp. 5044-5057
-
-
Cilibrizzi, A.1
Quinn, M.T.2
Kirpotina, L.N.3
Schepetkin, I.A.4
Holderness, J.5
Ye, R.D.6
Rabiet, M.J.7
Biancalani, C.8
Cesari, N.9
Graziano, A.10
Vergelli, C.11
Pieretti, S.12
dal Piaz, V.13
Giovannoni, M.P.14
-
91
-
-
33746849034
-
Neuroprotective agents for clinical trials in ALS: A systematic assessment
-
Traynor, B.J.; Bruijn, L.;. Conwit, R.; Beal, F.; O'Neill, G., Fagan, C., Cudkowicz, M.E. Neuroprotective agents for clinical trials in ALS: A systematic assessment. Neurology, 2006, 67, 20-27.
-
(2006)
Neurology
, vol.67
, pp. 20-27
-
-
Traynor, B.J.1
Bruijn, L.2
Conwit, R.3
Beal, F.4
O'Neill, G.5
Fagan, C.6
Cudkowicz, M.E.7
-
92
-
-
48349092132
-
A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS
-
Gordon, P.H.; Cheung, Y.K.; Levin, B.; Andrews, H.; Doorish, C.; Macarthur, R.B.; Montes, J.; Bednarz, K.; Florence, J.; Rowin, J.; Boylan, K.; Mozaffar, T.; Tandan, R.; Mitsumoto, H.; Kelvin, E.A.; Chapin, J.; Bedlack, R.; Rivner, M.; McCluskey, L.F.; Pestronk, A.; Graves, M.; Sorenson, E.J.; Barohn, R.J.; Belsh, J.M.; Lou, J.S.; Levine, T.; Saperstein, D.; Miller, R.G.; Scelsa, S.N. A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS. Amyotroph. Lateral Scler., 2008, 9, 212-222.
-
(2008)
Amyotroph. Lateral Scler
, vol.9
, pp. 212-222
-
-
Gordon, P.H.1
Cheung, Y.K.2
Levin, B.3
Andrews, H.4
Doorish, C.5
Macarthur, R.B.6
Montes, J.7
Bednarz, K.8
Florence, J.9
Rowin, J.10
Boylan, K.11
Mozaffar, T.12
Tandan, R.13
Mitsumoto, H.14
Kelvin, E.A.15
Chapin, J.16
Bedlack, R.17
Rivner, M.18
McCluskey, L.F.19
Pestronk, A.20
Graves, M.21
Sorenson, E.J.22
Barohn, R.J.23
Belsh, J.M.24
Lou, J.S.25
Levine, T.26
Saperstein, D.27
Miller, R.G.28
Scelsa, S.N.29
more..
-
93
-
-
33748904559
-
Structure-activity relationshio of neuroprotective and reactive oxygen species scavenging activities for allium organosulfur compounds
-
Kim, J-M.; Chang, H.J.; Kim, W-K.; Chang, N.; Chin, H.S. Structure-activity relationshio of neuroprotective and reactive oxygen species scavenging activities for allium organosulfur compounds. J. Agric. Food. Chem. 2006, 54, 6547-6553.
-
(2006)
J. Agric. Food. Chem
, vol.54
, pp. 6547-6553
-
-
Kim, J.-M.1
Chang, H.J.2
Kim, W.-K.3
Chang, N.4
Chin, H.S.5
-
94
-
-
14044258481
-
Peptides containing 4-amino-1,2-dithiolane-4-carboxylic acid (Adt): Conformation of Boc-Adt-Adt-NHMe and NH···S interactions
-
Morera, E.; Nalli, M.; Mollica, A.; Paglialunga Paradisi, M.; Aschi, M.; Gavuzzo, E.; Mazza, F.; Lucente, G. Peptides containing 4-amino-1,2-dithiolane-4-carboxylic acid (Adt): conformation of Boc-Adt-Adt-NHMe and NH···S interactions. J. Pept. Sci. 2005, 11, 104-112.
-
(2005)
J. Pept. Sci
, vol.11
, pp. 104-112
-
-
Morera, E.1
Nalli, M.2
Mollica, A.3
Paglialunga, P.M.4
Aschi, M.5
Gavuzzo, E.6
Mazza, F.7
Lucente, G.8
-
95
-
-
67650164757
-
Synthesis and evaluation of new endomorphin analogues modifies at the Pro2 residue
-
Torino, D.; Mollica, A.; Pinnen, F.; Lucente, G.; Feliciani, F.; Davis, P.; Lai, J.; Ma, S.-W., Porreca, F.; Hruby, V. J. Synthesis and evaluation of new endomorphin analogues modifies at the Pro2 residue. Bioorg. Med. Chem. Lett. 2009, 19, 4115-4118.
-
(2009)
Bioorg. Med. Chem. Lett
, vol.19
, pp. 4115-4118
-
-
Torino, D.1
Mollica, A.2
Pinnen, F.3
Lucente, G.4
Feliciani, F.5
Davis, P.6
Lai, J.7
Ma, S.-W.8
Porreca, F.9
Hruby, V.J.10
-
96
-
-
33845614389
-
Endomorphin-2, an endogenous tetrapeptide, protects against Ab1-42 in vitro and in vivo
-
Szegedi, V.; Juhàsz, G.; Ròzsa, E.; Gabriella, J.V.; Datki, Z.; Fulop, L.; Bozsò, Z.; Lakatos, A.; Laczkò, I.; Farkas, T.; Kis, Z.; Tòth, G.; Soòs, K.; Zaràndi, M.; Budai, D.; Toldi, J.; Penke, B. Endomorphin-2, an endogenous tetrapeptide, protects against Ab1-42 in vitro and in vivo. FASEB J. 2006, 20, 1191-1193.
-
(2006)
FASEB J
, vol.20
, pp. 1191-1193
-
-
Szegedi, V.1
Juhàsz, G.2
Ròzsa, E.3
Gabriella, J.V.4
Datki, Z.5
Fulop, L.6
Bozsò, Z.7
Lakatos, A.8
Laczkò, I.9
Farkas, T.10
Kis, Z.11
Tòth, G.12
Soòs, K.13
Zaràndi, M.14
Budai, D.15
Toldi, J.16
Penke, B.17
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