Inhibition by naloxone stereoisomers of β-amyloid peptide (1-42)-induced superoxide production in microglia and degeneration of cortical and mesencephalic neurons

Journal of Pharmacology and Experimental Therapeutics

Volumn 302, Issue 3, 2002, Pages 1212-1219

  Liu, Yuxin ^a   Qin, Liya ^a   Wilson, Belinda C ^b   An, Lijia ^a   Hong, Jau Shyong ^b   Liu, Bin ^a,b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

17 METHYLNALOXONE; AMINE; AMYLOID BETA PROTEIN; NALOXONE; OPIATE RECEPTOR; SUPEROXIDE;

ANIMAL CELL; ARTICLE; BRAIN CORTEX; CELL COUNT; CELL CULTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EMBRYO; ENANTIOMER; GLIA CELL; IMMUNOCYTOCHEMISTRY; ISOMER; MESENCEPHALON; MICROGLIA; NERVE DEGENERATION; NEUROPROTECTION; NEUROTRANSMITTER UPTAKE; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOISOMERISM;

AMYLOID BETA-PROTEIN; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; DOPAMINE; GAMMA-AMINOBUTYRIC ACID; IMMUNOHISTOCHEMISTRY; MALE; MESENCEPHALON; MICROGLIA; NALOXONE; NARCOTIC ANTAGONISTS; NERVE DEGENERATION; NEURONS; PEPTIDE FRAGMENTS; RATS; RATS, INBRED F344; STEREOISOMERISM; SUPEROXIDES; TYROSINE 3-MONOOXYGENASE;

EID: 0036721255     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.035956     Document Type: Article

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