High yield of human monoclonal antibody produced by stably transfected drosophila schneider 2 cells in perfusion culture using wave bioreactor

Molecular Biotechnology

Volumn 52, Issue 2, 2012, Pages 170-179

  Wang, Lulan ^a   Hu, Hongxing ^a   Yang, Jianjun ^b   Wang, Feng ^a   Kaisermayer, Christian ^c   Zhou, Paul ^a  

^a INSTITUTE PASTEUR OF SHANGHAI   (China)

^b GE GLOBAL RESEARCH   (China)

^c UNIVERSITY OF AGRICULTURAL SCIENCES   (Austria)

Author keywords

Drosophila S2 cells; Human monoclonal antibody; Influenza virus; Perfusion; Wave bioreactor

Indexed keywords

ANTIBODY PRODUCTION; BATCH CULTURE; HEAVY AND LIGHT CHAINS; HIGH YIELD; INFLUENZA VIRUS; INSECT CELL LINES; LARGE-SCALE PRODUCTION; PERFUSION; PERFUSION CULTURES; PROTEIN PRODUCTION; SCHNEIDER; TRANSFECTANTS; VIABLE CELLS;

BATCH CELL CULTURE; BIOREACTORS; CELLS; CLONING; CYTOLOGY; MAMMALS; VIRUSES;

MONOCLONAL ANTIBODIES;

HEMAGGLUTININ; HUMAN MONOCLONAL ANTIBODY;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; BACTERIUM CULTURE; BIOREACTOR; CELL CLONE; CELL DENSITY; CELL GROWTH; CONTROLLED STUDY; DILUTION; DROSOPHILA; INFLUENZA VIRUS A H5N1; LIGHT CHAIN; NONHUMAN;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, VIRAL; BIOREACTORS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CELLS, CULTURED; DROSOPHILA; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; PERFUSION; TRANSFECTION;

EID: 84867377780     PISSN: 10736085     EISSN: 15590305     Source Type: Journal    
DOI: 10.1007/s12033-011-9484-5     Document Type: Article

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