-
1
-
-
0034886143
-
Toll-like receptors: critical proteins linking innate and acquired immunity
-
Akira S, Takeda K, Kaisho T, (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2: 675-680.
-
(2001)
Nat Immunol
, vol.2
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
2
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
-
Kawai T, Akira S, (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11: 373-384.
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
3
-
-
0036467392
-
Toll-like receptors: key mediators of microbe detection
-
Underhill DM, Ozinsky A, (2002) Toll-like receptors: key mediators of microbe detection. Curr Opin Immunol 14: 103-110.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 103-110
-
-
Underhill, D.M.1
Ozinsky, A.2
-
4
-
-
0032170215
-
Genetic and physical mapping of the Lps locus: identification of the toll-4 receptor as a candidate gene in the critical region
-
Poltorak A, Smirnova I, He X, Liu MY, Van Huffel C, et al. (1998) Genetic and physical mapping of the Lps locus: identification of the toll-4 receptor as a candidate gene in the critical region. Blood Cells Mol Dis 24: 340-355.
-
(1998)
Blood Cells Mol Dis
, vol.24
, pp. 340-355
-
-
Poltorak, A.1
Smirnova, I.2
He, X.3
Liu, M.Y.4
Van Huffel, C.5
-
5
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
-
Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC, (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249: 1431-1433.
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
Ulevitch, R.J.4
Mathison, J.C.5
-
6
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai Y, Akashi S, Nagafuku M, Ogata M, Iwakura Y, et al. (2002) Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat Immunol 3: 667-672.
-
(2002)
Nat Immunol
, vol.3
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
-
7
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
-
Shimazu R, Akashi S, Ogata H, Nagai Y, Fukudome K, et al. (1999) MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med 189: 1777-1782.
-
(1999)
J Exp Med
, vol.189
, pp. 1777-1782
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
Nagai, Y.4
Fukudome, K.5
-
8
-
-
0025107568
-
Structure and function of lipopolysaccharide binding protein
-
Schumann RR, Leong SR, Flaggs GW, Gray PW, Wright SD, et al. (1990) Structure and function of lipopolysaccharide binding protein. Science 249: 1429-1431.
-
(1990)
Science
, vol.249
, pp. 1429-1431
-
-
Schumann, R.R.1
Leong, S.R.2
Flaggs, G.W.3
Gray, P.W.4
Wright, S.D.5
-
9
-
-
0030685133
-
Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection
-
Jack RS, Fan X, Bernheiden M, Rune G, Ehlers M, et al. (1997) Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection. Nature 389: 742-745.
-
(1997)
Nature
, vol.389
, pp. 742-745
-
-
Jack, R.S.1
Fan, X.2
Bernheiden, M.3
Rune, G.4
Ehlers, M.5
-
10
-
-
0036453356
-
TLR2: cellular sensor for microbial and endogenous molecular patterns
-
Kirschning CJ, Schumann RR, (2002) TLR2: cellular sensor for microbial and endogenous molecular patterns. Curr Top Microbiol Immunol 270: 121-144.
-
(2002)
Curr Top Microbiol Immunol
, vol.270
, pp. 121-144
-
-
Kirschning, C.J.1
Schumann, R.R.2
-
11
-
-
13444280215
-
CD36 is a sensor of diacylglycerides
-
Hoebe K, Georgel P, Rutschmann S, Du X, Mudd S, et al. (2005) CD36 is a sensor of diacylglycerides. Nature 433: 523-527.
-
(2005)
Nature
, vol.433
, pp. 523-527
-
-
Hoebe, K.1
Georgel, P.2
Rutschmann, S.3
Du, X.4
Mudd, S.5
-
12
-
-
33644508366
-
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
-
Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, et al. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO J 25: 683-692.
-
(2006)
EMBO J
, vol.25
, pp. 683-692
-
-
Husebye, H.1
Halaas, Ø.2
Stenmark, H.3
Tunheim, G.4
Sandanger, Ø.5
-
13
-
-
40949134086
-
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta
-
Kagan JC, Su T, Horng T, Chow A, Akira S, et al. (2008) TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat Immunol 9: 361-368.
-
(2008)
Nat Immunol
, vol.9
, pp. 361-368
-
-
Kagan, J.C.1
Su, T.2
Horng, T.3
Chow, A.4
Akira, S.5
-
14
-
-
77956329223
-
Murine toll-like receptor 2 activation induces type I interferon responses from endolysosomal compartments
-
Dietrich N, Lienenklaus S, Weiss S, Gekara NO, (2010) Murine toll-like receptor 2 activation induces type I interferon responses from endolysosomal compartments. PLoS One 5: e10250.
-
(2010)
PLoS One
, vol.5
-
-
Dietrich, N.1
Lienenklaus, S.2
Weiss, S.3
Gekara, N.O.4
-
15
-
-
0023800594
-
Physiology of lipoteichoic acids in bacteria
-
Fischer W, (1988) Physiology of lipoteichoic acids in bacteria. Adv Microb Physiol 29: 233-302.
-
(1988)
Adv Microb Physiol
, vol.29
, pp. 233-302
-
-
Fischer, W.1
-
16
-
-
0347479228
-
A continuum of anionic charge: structures and functions of D-alanyl-teichoic acids in gram-positive bacteria
-
Neuhaus FC, Baddiley J, (2003) A continuum of anionic charge: structures and functions of D-alanyl-teichoic acids in gram-positive bacteria. Microbiol Mol Biol Rev 67: 686-723.
-
(2003)
Microbiol Mol Biol Rev
, vol.67
, pp. 686-723
-
-
Neuhaus, F.C.1
Baddiley, J.2
-
17
-
-
73649136784
-
The wall teichoic acid and lipoteichoic acid polymers of Staphylococcus aureus
-
Xia G, Kohler T, Peschel A, (2010) The wall teichoic acid and lipoteichoic acid polymers of Staphylococcus aureus. Int J Med Microbiol 300: 148-154.
-
(2010)
Int J Med Microbiol
, vol.300
, pp. 148-154
-
-
Xia, G.1
Kohler, T.2
Peschel, A.3
-
18
-
-
0016813833
-
Synthesis and excretion of glycerol teichoic acid during growth of two streptococcal species
-
Joseph R, Shockman GD, (1975) Synthesis and excretion of glycerol teichoic acid during growth of two streptococcal species. Infect Immun 12: 333-338.
-
(1975)
Infect Immun
, vol.12
, pp. 333-338
-
-
Joseph, R.1
Shockman, G.D.2
-
19
-
-
0032719350
-
Clinical outcome in pneumococcal meningitis correlates with CSF lipoteichoic acid concentrations
-
Schneider O, Michel U, Zysk G, Dubuis O, Nau R, (1999) Clinical outcome in pneumococcal meningitis correlates with CSF lipoteichoic acid concentrations. Neurology 53: 1584-1587.
-
(1999)
Neurology
, vol.53
, pp. 1584-1587
-
-
Schneider, O.1
Michel, U.2
Zysk, G.3
Dubuis, O.4
Nau, R.5
-
20
-
-
0017944046
-
Excretion of lipoteichoic acid by group A streptococci. Influence of penicillin on excretion and loss of ability to adhere to human oral mucosal cells
-
Alkan ML, Beachey EH, (1978) Excretion of lipoteichoic acid by group A streptococci. Influence of penicillin on excretion and loss of ability to adhere to human oral mucosal cells. J Clin Invest 61: 671-677.
-
(1978)
J Clin Invest
, vol.61
, pp. 671-677
-
-
Alkan, M.L.1
Beachey, E.H.2
-
21
-
-
0037379522
-
Rifampin followed by ceftriaxone for experimental meningitis decreases lipoteichoic acid concentrations in cerebrospinal fluid and reduces neuronal damage in comparison to ceftriaxone alone
-
Gerber J, Pohl K, Sander V, Bunkowski S, Nau R, (2003) Rifampin followed by ceftriaxone for experimental meningitis decreases lipoteichoic acid concentrations in cerebrospinal fluid and reduces neuronal damage in comparison to ceftriaxone alone. Antimicrob Agents Chemother 47: 1313-1317.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 1313-1317
-
-
Gerber, J.1
Pohl, K.2
Sander, V.3
Bunkowski, S.4
Nau, R.5
-
22
-
-
34548608447
-
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
-
Jin MS, Kim SE, Heo JY, Lee ME, Kim HM, et al. (2007) Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell 130: 1071-1082.
-
(2007)
Cell
, vol.130
, pp. 1071-1082
-
-
Jin, M.S.1
Kim, S.E.2
Heo, J.Y.3
Lee, M.E.4
Kim, H.M.5
-
23
-
-
0037124358
-
Synthetic lipoteichoic acid from Staphylococcus aureus is a potent stimulus of cytokine release
-
Morath S, Stadelmaier A, Geyer A, Schmidt RR, Hartung T, (2002) Synthetic lipoteichoic acid from Staphylococcus aureus is a potent stimulus of cytokine release. J Exp Med 195: 1635-1640.
-
(2002)
J Exp Med
, vol.195
, pp. 1635-1640
-
-
Morath, S.1
Stadelmaier, A.2
Geyer, A.3
Schmidt, R.R.4
Hartung, T.5
-
24
-
-
0037446536
-
Definition of structural prerequisites for lipoteichoic acid-inducible cytokine induction by synthetic derivatives
-
Deininger S, Stadelmaier A, von Aulock S, Morath S, Schmidt RR, et al. (2003) Definition of structural prerequisites for lipoteichoic acid-inducible cytokine induction by synthetic derivatives. J Immunol 170: 4134-4138.
-
(2003)
J Immunol
, vol.170
, pp. 4134-4138
-
-
Deininger, S.1
Stadelmaier, A.2
von Aulock, S.3
Morath, S.4
Schmidt, R.R.5
-
25
-
-
33645975827
-
Monocyte and macrophage activation by lipoteichoic Acid is independent of alanine and is potentiated by hemoglobin
-
Hasty DL, Meron-Sudai S, Cox KH, Nagorna T, Ruiz-Bustos E, et al. (2006) Monocyte and macrophage activation by lipoteichoic Acid is independent of alanine and is potentiated by hemoglobin. J Immunol 176: 5567-5576.
-
(2006)
J Immunol
, vol.176
, pp. 5567-5576
-
-
Hasty, D.L.1
Meron-Sudai, S.2
Cox, K.H.3
Nagorna, T.4
Ruiz-Bustos, E.5
-
26
-
-
34248351967
-
Enhancement of macrophage stimulation by lipoteichoic acid and the costimulant hemoglobin is dependent on Toll-like receptors 2 and 4
-
Cox KH, Ofek I, Hasty DL, (2007) Enhancement of macrophage stimulation by lipoteichoic acid and the costimulant hemoglobin is dependent on Toll-like receptors 2 and 4. Infect Immun 75: 2638-2641.
-
(2007)
Infect Immun
, vol.75
, pp. 2638-2641
-
-
Cox, K.H.1
Ofek, I.2
Hasty, D.L.3
-
27
-
-
34648860530
-
Free hemoglobin: a dangerous signal for the immune system in patients with carotid atherosclerosis?
-
Buttari B, Profumo E, Petrone L, Pietraforte D, Siracusano A, et al. (2007) Free hemoglobin: a dangerous signal for the immune system in patients with carotid atherosclerosis? Ann N Y Acad Sci 1107: 42-50.
-
(2007)
Ann N Y Acad Sci
, vol.1107
, pp. 42-50
-
-
Buttari, B.1
Profumo, E.2
Petrone, L.3
Pietraforte, D.4
Siracusano, A.5
-
28
-
-
79951819358
-
Fusobacterium nucleatum binding to complement regulatory protein CD46 modulates the expression and secretion of cytokines and matrix metalloproteinases by oral epithelial cells
-
Mahtout H, Chandad F, Rojo JM, Grenier D, (2011) Fusobacterium nucleatum binding to complement regulatory protein CD46 modulates the expression and secretion of cytokines and matrix metalloproteinases by oral epithelial cells. J Periodontol 82: 311-319.
-
(2011)
J Periodontol
, vol.82
, pp. 311-319
-
-
Mahtout, H.1
Chandad, F.2
Rojo, J.M.3
Grenier, D.4
-
29
-
-
80051802504
-
Streptolysin S-like virulence factors: the continuing sagA
-
Molloy EM, Cotter PD, Hill C, Mitchell DA, Ross RP, (2011) Streptolysin S-like virulence factors: the continuing sagA. Nat Rev Microbiol 9: 670-681.
-
(2011)
Nat Rev Microbiol
, vol.9
, pp. 670-681
-
-
Molloy, E.M.1
Cotter, P.D.2
Hill, C.3
Mitchell, D.A.4
Ross, R.P.5
-
30
-
-
0034033679
-
Genetic relatedness and superantigen expression in group A streptococcus serotype M1 isolates from patients with severe and nonsevere invasive diseases
-
Chatellier S, Ihendyane N, Kansal RG, Khambaty F, Basma H, et al. (2000) Genetic relatedness and superantigen expression in group A streptococcus serotype M1 isolates from patients with severe and nonsevere invasive diseases. Infect Immun 68: 3523-3534.
-
(2000)
Infect Immun
, vol.68
, pp. 3523-3534
-
-
Chatellier, S.1
Ihendyane, N.2
Kansal, R.G.3
Khambaty, F.4
Basma, H.5
-
31
-
-
0035808774
-
Structure-function relationship of cytokine induction by lipoteichoic acid from Staphylococcus aureus
-
Morath S, Geyer A, Hartung T, (2001) Structure-function relationship of cytokine induction by lipoteichoic acid from Staphylococcus aureus. J Exp Med 193: 393-397.
-
(2001)
J Exp Med
, vol.193
, pp. 393-397
-
-
Morath, S.1
Geyer, A.2
Hartung, T.3
-
32
-
-
0035142605
-
Commercial preparations of lipoteichoic acid contain endotoxin that contributes to activation of mouse macrophages in vitro
-
Gao JJ, Xue Q, Zuvanich EG, Haghi KR, Morrison DC, (2001) Commercial preparations of lipoteichoic acid contain endotoxin that contributes to activation of mouse macrophages in vitro. Infect Immun 69: 751-757.
-
(2001)
Infect Immun
, vol.69
, pp. 751-757
-
-
Gao, J.J.1
Xue, Q.2
Zuvanich, E.G.3
Haghi, K.R.4
Morrison, D.C.5
-
33
-
-
0023636720
-
A murine macrophage cell line, immortalized by v-raf and v-myc oncogenes, exhibits normal macrophage functions
-
Blasi E, Radzioch D, Durum SK, Varesio L, (1987) A murine macrophage cell line, immortalized by v-raf and v-myc oncogenes, exhibits normal macrophage functions. Eur J Immunol 17: 1491-1498.
-
(1987)
Eur J Immunol
, vol.17
, pp. 1491-1498
-
-
Blasi, E.1
Radzioch, D.2
Durum, S.K.3
Varesio, L.4
-
34
-
-
58849167699
-
The isolation and characterization of murine macrophages
-
Chapter 14: Unit 14
-
Zhang X, Goncalves R, Mosser DM (2008) The isolation and characterization of murine macrophages. Curr Protoc Immunol Chapter 14: Unit 14.11.
-
(2008)
Curr Protoc Immunol
, pp. 11
-
-
Zhang, X.1
Goncalves, R.2
Mosser, D.M.3
-
35
-
-
0037022296
-
Human macrophage activation programs induced by bacterial pathogens
-
Nau GJ, Richmond JF, Schlesinger A, Jennings EG, Lander ES, et al. (2002) Human macrophage activation programs induced by bacterial pathogens. Proc Natl Acad Sci U S A 99: 1503-1508.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 1503-1508
-
-
Nau, G.J.1
Richmond, J.F.2
Schlesinger, A.3
Jennings, E.G.4
Lander, E.S.5
-
36
-
-
41149084666
-
The Innate Immune Database (IIDB)
-
Korb M, Rust AG, Thorsson V, Battail C, Li B, et al. (2008) The Innate Immune Database (IIDB). BMC Immunol 9: 7.
-
(2008)
BMC Immunol
, vol.9
, pp. 7
-
-
Korb, M.1
Rust, A.G.2
Thorsson, V.3
Battail, C.4
Li, B.5
-
37
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang dW, Sherman BT, Lempicki RA, (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
38
-
-
34547589578
-
DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists
-
Huang dW, Sherman BT, Tan Q, Kir J, Liu D, et al. (2007) DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res 35: W169-175.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Huang, W.1
Sherman, B.T.2
Tan, Q.3
Kir, J.4
Liu, D.5
-
39
-
-
0023724778
-
I kappa B: a specific inhibitor of the NF-kappa B transcription factor
-
Baeuerle PA, Baltimore D, (1988) I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science 242: 540-546.
-
(1988)
Science
, vol.242
, pp. 540-546
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
40
-
-
0028986075
-
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation
-
Brown K, Gerstberger S, Carlson L, Franzoso G, Siebenlist U, (1995) Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science 267: 1485-1488.
-
(1995)
Science
, vol.267
, pp. 1485-1488
-
-
Brown, K.1
Gerstberger, S.2
Carlson, L.3
Franzoso, G.4
Siebenlist, U.5
-
41
-
-
0028978032
-
Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli
-
Traenckner EB, Pahl HL, Henkel T, Schmidt KN, Wilk S, et al. (1995) Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli. EMBO J 14: 2876-2883.
-
(1995)
EMBO J
, vol.14
, pp. 2876-2883
-
-
Traenckner, E.B.1
Pahl, H.L.2
Henkel, T.3
Schmidt, K.N.4
Wilk, S.5
-
42
-
-
0031057644
-
Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm
-
Arenzana-Seisdedos F, Turpin P, Rodriguez M, Thomas D, Hay RT, et al. (1997) Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm. J Cell Sci 110 (Pt 3): 369-378.
-
(1997)
J Cell Sci
, vol.110
, Issue.Pt 3
, pp. 369-378
-
-
Arenzana-Seisdedos, F.1
Turpin, P.2
Rodriguez, M.3
Thomas, D.4
Hay, R.T.5
-
43
-
-
80053646173
-
A subclass of acylated anti-inflammatory mediators usurp Toll-like receptor 2 to inhibit neutrophil recruitment through peroxisome proliferator-activated receptor gamma
-
Long EM, Klimowicz AC, Paula-Neto HA, Millen B, McCafferty DM, et al. (2011) A subclass of acylated anti-inflammatory mediators usurp Toll-like receptor 2 to inhibit neutrophil recruitment through peroxisome proliferator-activated receptor gamma. Proc Natl Acad Sci U S A 108: 16357-16362.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 16357-16362
-
-
Long, E.M.1
Klimowicz, A.C.2
Paula-Neto, H.A.3
Millen, B.4
McCafferty, D.M.5
-
44
-
-
65949097502
-
Lipoteichoic acid induces unique inflammatory responses when compared to other toll-like receptor 2 ligands
-
Long EM, Millen B, Kubes P, Robbins SM, (2009) Lipoteichoic acid induces unique inflammatory responses when compared to other toll-like receptor 2 ligands. PLoS One 4: e5601.
-
(2009)
PLoS One
, vol.4
-
-
Long, E.M.1
Millen, B.2
Kubes, P.3
Robbins, S.M.4
-
45
-
-
33646892646
-
Dynasore, a cell-permeable inhibitor of dynamin
-
Macia E, Ehrlich M, Massol R, Boucrot E, Brunner C, et al. (2006) Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell 10: 839-850.
-
(2006)
Dev Cell
, vol.10
, pp. 839-850
-
-
Macia, E.1
Ehrlich, M.2
Massol, R.3
Boucrot, E.4
Brunner, C.5
-
46
-
-
13444257582
-
Regulation of lipopolysaccharide-inducible genes by MyD88 and Toll/IL-1 domain containing adaptor inducing IFN-beta
-
Hirotani T, Yamamoto M, Kumagai Y, Uematsu S, Kawase I, et al. (2005) Regulation of lipopolysaccharide-inducible genes by MyD88 and Toll/IL-1 domain containing adaptor inducing IFN-beta. Biochem Biophys Res Commun 328: 383-392.
-
(2005)
Biochem Biophys Res Commun
, vol.328
, pp. 383-392
-
-
Hirotani, T.1
Yamamoto, M.2
Kumagai, Y.3
Uematsu, S.4
Kawase, I.5
-
47
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T, Adachi O, Ogawa T, Takeda K, Akira S, (1999) Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11: 115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
48
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, et al. (2003) Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301: 640-643.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
-
49
-
-
33746731651
-
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2
-
Yu M, Wang H, Ding A, Golenbock DT, Latz E, et al. (2006) HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock 26: 174-179.
-
(2006)
Shock
, vol.26
, pp. 174-179
-
-
Yu, M.1
Wang, H.2
Ding, A.3
Golenbock, D.T.4
Latz, E.5
-
50
-
-
33645461206
-
High mobility group box 1 protein interacts with multiple Toll-like receptors
-
Park JS, Gamboni-Robertson F, He Q, Svetkauskaite D, Kim JY, et al. (2006) High mobility group box 1 protein interacts with multiple Toll-like receptors. Am J Physiol Cell Physiol 290: C917-924.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Park, J.S.1
Gamboni-Robertson, F.2
He, Q.3
Svetkauskaite, D.4
Kim, J.Y.5
-
51
-
-
61449116805
-
Bacterial endotoxin induces the release of high mobility group box 1 via the IFN-beta signaling pathway
-
Kim JH, Kim SJ, Lee IS, Lee MS, Uematsu S, et al. (2009) Bacterial endotoxin induces the release of high mobility group box 1 via the IFN-beta signaling pathway. J Immunol 182: 2458-2466.
-
(2009)
J Immunol
, vol.182
, pp. 2458-2466
-
-
Kim, J.H.1
Kim, S.J.2
Lee, I.S.3
Lee, M.S.4
Uematsu, S.5
-
52
-
-
77954699484
-
Synergistic inflammation is induced by blood degradation products with microbial Toll-like receptor agonists and is blocked by hemopexin
-
Lin T, Kwak YH, Sammy F, He P, Thundivalappil S, et al. (2010) Synergistic inflammation is induced by blood degradation products with microbial Toll-like receptor agonists and is blocked by hemopexin. J Infect Dis 202: 624-632.
-
(2010)
J Infect Dis
, vol.202
, pp. 624-632
-
-
Lin, T.1
Kwak, Y.H.2
Sammy, F.3
He, P.4
Thundivalappil, S.5
-
53
-
-
59649116170
-
Structural investigations into the interaction of hemoglobin and part structures with bacterial endotoxins
-
Howe J, Garidel P, Roessle M, Richter W, Alexander C, et al. (2008) Structural investigations into the interaction of hemoglobin and part structures with bacterial endotoxins. Innate Immun 14: 39-49.
-
(2008)
Innate Immun
, vol.14
, pp. 39-49
-
-
Howe, J.1
Garidel, P.2
Roessle, M.3
Richter, W.4
Alexander, C.5
-
54
-
-
77958505493
-
Heme amplifies the innate immune response to microbial molecules through spleen tyrosine kinase (Syk)-dependent reactive oxygen species generation
-
Fernandez PL, Dutra FF, Alves L, Figueiredo RT, Mourão-Sa D, et al. (2010) Heme amplifies the innate immune response to microbial molecules through spleen tyrosine kinase (Syk)-dependent reactive oxygen species generation. J Biol Chem 285: 32844-32851.
-
(2010)
J Biol Chem
, vol.285
, pp. 32844-32851
-
-
Fernandez, P.L.1
Dutra, F.F.2
Alves, L.3
Figueiredo, R.T.4
Mourão-Sa, D.5
-
55
-
-
33846089453
-
Biophysical characterization of the interaction of endotoxins with hemoglobins
-
Howe J, Hammer M, Alexander C, Rössle M, Fournier K, et al. (2007) Biophysical characterization of the interaction of endotoxins with hemoglobins. Med Chem 3: 13-20.
-
(2007)
Med Chem
, vol.3
, pp. 13-20
-
-
Howe, J.1
Hammer, M.2
Alexander, C.3
Rössle, M.4
Fournier, K.5
-
56
-
-
57349157136
-
Hemoglobin enhances the biological activity of synthetic and natural bacterial (endotoxic) virulence factors: a general principle
-
Howe J, Richter W, Hawkins L, Rössle M, Alexander C, et al. (2008) Hemoglobin enhances the biological activity of synthetic and natural bacterial (endotoxic) virulence factors: a general principle. Med Chem 4: 520-525.
-
(2008)
Med Chem
, vol.4
, pp. 520-525
-
-
Howe, J.1
Richter, W.2
Hawkins, L.3
Rössle, M.4
Alexander, C.5
-
57
-
-
77953377110
-
Hemoglobin transforms anti-inflammatory Salmonella typhi virulence polysaccharide into a TLR-2 agonist
-
Garg R, Qadri A, (2010) Hemoglobin transforms anti-inflammatory Salmonella typhi virulence polysaccharide into a TLR-2 agonist. J Immunol 184: 5980-5987.
-
(2010)
J Immunol
, vol.184
, pp. 5980-5987
-
-
Garg, R.1
Qadri, A.2
-
58
-
-
77950627035
-
Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy
-
Van Gorp H, Delputte PL, Nauwynck HJ, (2010) Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy. Mol Immunol 47: 1650-1660.
-
(2010)
Mol Immunol
, vol.47
, pp. 1650-1660
-
-
Van Gorp, H.1
Delputte, P.L.2
Nauwynck, H.J.3
-
60
-
-
77949521505
-
Haptoglobin: basic and clinical aspects
-
Levy AP, Asleh R, Blum S, Levy NS, Miller-Lotan R, et al. (2010) Haptoglobin: basic and clinical aspects. Antioxid Redox Signal 12: 293-304.
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 293-304
-
-
Levy, A.P.1
Asleh, R.2
Blum, S.3
Levy, N.S.4
Miller-Lotan, R.5
-
61
-
-
0028131671
-
Hemoglobin, a newly recognized lipopolysaccharide (LPS)-binding protein that enhances LPS biological activity
-
Kaca W, Roth RI, Levin J, (1994) Hemoglobin, a newly recognized lipopolysaccharide (LPS)-binding protein that enhances LPS biological activity. J Biol Chem 269: 25078-25084.
-
(1994)
J Biol Chem
, vol.269
, pp. 25078-25084
-
-
Kaca, W.1
Roth, R.I.2
Levin, J.3
-
62
-
-
0027145583
-
Production of modified crosslinked cell-free hemoglobin for human use: the role of quantitative determination of endotoxin contamination
-
Roth RI, Levin J, Chapman KW, Schmeizl M, Rickles FR, (1993) Production of modified crosslinked cell-free hemoglobin for human use: the role of quantitative determination of endotoxin contamination. Transfusion 33: 919-924.
-
(1993)
Transfusion
, vol.33
, pp. 919-924
-
-
Roth, R.I.1
Levin, J.2
Chapman, K.W.3
Schmeizl, M.4
Rickles, F.R.5
-
63
-
-
0032891193
-
Hemoglobin infusion augments the tumor necrosis factor response to bacterial endotoxin (lipopolysaccharide) in mice
-
Su D, Roth RI, Levin J, (1999) Hemoglobin infusion augments the tumor necrosis factor response to bacterial endotoxin (lipopolysaccharide) in mice. Crit Care Med 27: 771-778.
-
(1999)
Crit Care Med
, vol.27
, pp. 771-778
-
-
Su, D.1
Roth, R.I.2
Levin, J.3
-
64
-
-
34548763155
-
Hemoglobin and LPS act in synergy to amplify the inflammatory response
-
Bodet C, Chandad F, Grenier D, (2007) Hemoglobin and LPS act in synergy to amplify the inflammatory response. J Dent Res 86: 878-882.
-
(2007)
J Dent Res
, vol.86
, pp. 878-882
-
-
Bodet, C.1
Chandad, F.2
Grenier, D.3
-
65
-
-
0036123473
-
Free hemoglobin enhances tumor necrosis factor-alpha production in isolated human monocytes
-
Carrillo EH, Gordon LE, Richardson JD, Polk HC, (2002) Free hemoglobin enhances tumor necrosis factor-alpha production in isolated human monocytes. J Trauma 52: 449-452.
-
(2002)
J Trauma
, vol.52
, pp. 449-452
-
-
Carrillo, E.H.1
Gordon, L.E.2
Richardson, J.D.3
Polk, H.C.4
-
66
-
-
55449102885
-
Chemokines and cardiovascular risk
-
Aukrust P, Halvorsen B, Yndestad A, Ueland T, Øie E, et al. (2008) Chemokines and cardiovascular risk. Arterioscler Thromb Vasc Biol 28: 1909-1919.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1909-1919
-
-
Aukrust, P.1
Halvorsen, B.2
Yndestad, A.3
Ueland, T.4
Øie, E.5
-
67
-
-
0042351113
-
Expression of L-CCR in HEK 293 cells reveals functional responses to CCL2, CCL5, CCL7, and CCL8
-
Biber K, Zuurman MW, Homan H, Boddeke HW, (2003) Expression of L-CCR in HEK 293 cells reveals functional responses to CCL2, CCL5, CCL7, and CCL8. J Leukoc Biol 74: 243-251.
-
(2003)
J Leukoc Biol
, vol.74
, pp. 243-251
-
-
Biber, K.1
Zuurman, M.W.2
Homan, H.3
Boddeke, H.W.4
-
68
-
-
79952186298
-
MicroRNAs: the fine-tuners of Toll-like receptor signalling
-
O'Neill LA, Sheedy FJ, McCoy CE, (2011) MicroRNAs: the fine-tuners of Toll-like receptor signalling. Nat Rev Immunol 11: 163-175.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 163-175
-
-
O'Neill, L.A.1
Sheedy, F.J.2
McCoy, C.E.3
-
69
-
-
77951219696
-
MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization
-
Jennewein C, von Knethen A, Schmid T, Brüne B, (2010) MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization. J Biol Chem 285: 11846-11853.
-
(2010)
J Biol Chem
, vol.285
, pp. 11846-11853
-
-
Jennewein, C.1
von Knethen, A.2
Schmid, T.3
Brüne, B.4
-
70
-
-
34547120742
-
Characterization of heme as activator of Toll-like receptor 4
-
Figueiredo RT, Fernandez PL, Mourao-Sa DS, Porto BN, Dutra FF, et al. (2007) Characterization of heme as activator of Toll-like receptor 4. J Biol Chem 282: 20221-20229.
-
(2007)
J Biol Chem
, vol.282
, pp. 20221-20229
-
-
Figueiredo, R.T.1
Fernandez, P.L.2
Mourao-Sa, D.S.3
Porto, B.N.4
Dutra, F.F.5
-
71
-
-
79955045367
-
Low-dose endotoxin induces inflammation by selectively removing nuclear receptors and activating CCAAT/enhancer-binding protein δ
-
Maitra U, Gan L, Chang S, Li L, (2011) Low-dose endotoxin induces inflammation by selectively removing nuclear receptors and activating CCAAT/enhancer-binding protein δ. J Immunol 186: 4467-4473.
-
(2011)
J Immunol
, vol.186
, pp. 4467-4473
-
-
Maitra, U.1
Gan, L.2
Chang, S.3
Li, L.4
-
72
-
-
1542380035
-
Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
-
Park JS, Svetkauskaite D, He Q, Kim JY, Strassheim D, et al. (2004) Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 279: 7370-7377.
-
(2004)
J Biol Chem
, vol.279
, pp. 7370-7377
-
-
Park, J.S.1
Svetkauskaite, D.2
He, Q.3
Kim, J.Y.4
Strassheim, D.5
-
73
-
-
19944431800
-
RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages
-
Kokkola R, Andersson A, Mullins G, Ostberg T, Treutiger CJ, et al. (2005) RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scand J Immunol 61: 1-9.
-
(2005)
Scand J Immunol
, vol.61
, pp. 1-9
-
-
Kokkola, R.1
Andersson, A.2
Mullins, G.3
Ostberg, T.4
Treutiger, C.J.5
-
74
-
-
0028851635
-
The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
-
Hori O, Brett J, Slattery T, Cao R, Zhang J, et al. (1995) The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem 270: 25752-25761.
-
(1995)
J Biol Chem
, vol.270
, pp. 25752-25761
-
-
Hori, O.1
Brett, J.2
Slattery, T.3
Cao, R.4
Zhang, J.5
-
75
-
-
0037428250
-
HMGB1 interacts differentially with members of the Rel family of transcription factors
-
Agresti A, Lupo R, Bianchi ME, Müller S, (2003) HMGB1 interacts differentially with members of the Rel family of transcription factors. Biochem Biophys Res Commun 302: 421-426.
-
(2003)
Biochem Biophys Res Commun
, vol.302
, pp. 421-426
-
-
Agresti, A.1
Lupo, R.2
Bianchi, M.E.3
Müller, S.4
-
76
-
-
17144376810
-
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
-
Lotze MT, Tracey KJ, (2005) High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 5: 331-342.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 331-342
-
-
Lotze, M.T.1
Tracey, K.J.2
-
77
-
-
80052800427
-
Heat shock proteins and high mobility group box 1 protein lack cytokine function
-
Tsan MF, (2011) Heat shock proteins and high mobility group box 1 protein lack cytokine function. J Leukoc Biol 89: 847-853.
-
(2011)
J Leukoc Biol
, vol.89
, pp. 847-853
-
-
Tsan, M.F.1
-
78
-
-
0142137129
-
Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion
-
Bonaldi T, Talamo F, Scaffidi P, Ferrera D, Porto A, et al. (2003) Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J 22: 5551-5560.
-
(2003)
EMBO J
, vol.22
, pp. 5551-5560
-
-
Bonaldi, T.1
Talamo, F.2
Scaffidi, P.3
Ferrera, D.4
Porto, A.5
-
79
-
-
33751584837
-
Nucleocytoplasmic shuttling of HMGB1 is regulated by phosphorylation that redirects it toward secretion
-
Youn JH, Shin JS, (2006) Nucleocytoplasmic shuttling of HMGB1 is regulated by phosphorylation that redirects it toward secretion. J Immunol 177: 7889-7897.
-
(2006)
J Immunol
, vol.177
, pp. 7889-7897
-
-
Youn, J.H.1
Shin, J.S.2
-
80
-
-
44449162626
-
High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes
-
Youn JH, Oh YJ, Kim ES, Choi JE, Shin JS, (2008) High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes. J Immunol 180: 5067-5074.
-
(2008)
J Immunol
, vol.180
, pp. 5067-5074
-
-
Youn, J.H.1
Oh, Y.J.2
Kim, E.S.3
Choi, J.E.4
Shin, J.S.5
-
81
-
-
77954176954
-
HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products
-
Qin YH, Dai SM, Tang GS, Zhang J, Ren D, et al. (2009) HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products. J Immunol 183: 6244-6250.
-
(2009)
J Immunol
, vol.183
, pp. 6244-6250
-
-
Qin, Y.H.1
Dai, S.M.2
Tang, G.S.3
Zhang, J.4
Ren, D.5
|