Free hemoglobin enhances tumor necrosis factor-α production in isolated human monocytes

Journal of Trauma

Volumn 52, Issue 3, 2002, Pages 449-452

  Carrillo, Eddy H ^a,b,c   Gordon, Laura E ^a,c   Richardson, J David ^a,b   Polk, Hiram C ^a,b,c  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE HOSPITAL   (United States)

^c UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

Hemoglobin; Inflammation; Lipopolysaccharide; Tumor necrosis factor (TNF )

Indexed keywords

HEMOGLOBIN; LIPOPOLYSACCHARIDE; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; CELL ISOLATION; CELL STIMULATION; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEMOGLOBIN DETERMINATION; HUMAN; HUMAN CELL; INFLAMMATION; LIVER INJURY; MEDIATOR RELEASE; MONOCYTE; NORMAL HUMAN; PERITONEUM LAVAGE; PRIORITY JOURNAL; STATISTICAL ANALYSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ADULT; ANALYSIS OF VARIANCE; BILE ACIDS AND SALTS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; HEMOGLOBINS; HUMANS; LIPOPOLYSACCHARIDES; MIDDLE AGED; MONOCYTES; STATISTICS, NONPARAMETRIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036123473     PISSN: 00225282     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005373-200203000-00006     Document Type: Article

References (23)

1. Carrillo EH, Wohltmann C, Richardson JD, Polk HC Jr. Evolution in the treatment of complex blunt liver injuries. Curr Probl Surg. 2001; 38: 1-60.
2. Croce M, Fabian T, Menke P, et al. Non-operative management of blunt hepatic trauma is the treatment of choice for hemodynamically stable patients: results of a prospective trial. Ann Surg. 1995; 221: 744-755.
3. Richardson JD, Franklin GA, Lukan JK, et al. Evolution in the management of hepatic trauma: a 25-year perspective. Ann Surg. 2000; 232: 324-330.
4. Hackam DJ, Rothstein OD. Host response to laparoscopic surgery: mechanisms and clinical correlates. Can J Surg. 1998; 41: 103-111.
5. Carrillo EH, Reed DN, Gordon L, Spain DA, Richardson JD. Delayed laparoscopy facilitates the management of biliary peritonitis in patients with complex liver injuries. Surg Endosc. 2001; 15: 319-322.
6. Griffin M, Ochoa J, Boulanager BR. A minimally invasive approach to bile peritonitis after blunt liver injury. Am Surg. 2000; 66: 309-312.
7. Susan Budavari, ed. Hemoglobin. In: The Merck Index, 12th ed. Whitehouse Station, NJ: Merck Research Laboratories; 1996:794.
8. McFaul SJ, Bowman PD, Villa VM. Hemoglobin stimulates the release of proinflammatory cytokines from leukocytes in whole blood. J Lab Clin Med. 2000; 135: 263-269.
9. Su D, Roth RI, Yoshida M, Levin J. Hemoglobin increases mortality from bacterial endotoxin. Infect Immun. 1997; 65: 1258-1266.
10. McFaul SJ, Bowman PD, Villa VM, et al. Hemoglobin stimulates mononuclear leukocytes to release interleukin-8 and tumor necrosis factor-&agr;. Blood. 1994; 84: 3175-3181.
11. Johnson JL, Wallace BH, Mareen CD, et al. Intraperitoneal blood exacerbates the remote inflammatory response to murine peritonitis 'abstract'. J Trauma. 2001; 51: 253-260.
12. Andersson R, Tranberg KG, Alwmark A, Bengmark S. Factors influencing the outcome of E. coli peritonitis in rats. Acta Chir Scand. 1989; 155: 155-157.
13. Su D, Roth RI, Levin J. Hemoglobin infusion augments the tumor necrosis factor response to bacterial endotoxin (lipopolysaccharide) in mice. Crit Care Med. 1999; 27: 771-778.
14. Polk HC Jr, Miles AA. Enhancement of bacterial infection by ferric iron: kinetics, mechanisms, and surgical significance. Surgery. 1971; 70: 71-77.
15. Griffiths E, Cortes A, Gilbert N, Stevenson P, MacDonald S, Pepper D. Haemoglobin-based blood substitutes and sepsis. Lancet. 1995; 345: 158-160.
16. Goldman DW, Bryer RJ 3rd, Yeh D, Brockner-Ryan BA, Alayash AI. Acellular hemoglobin-mediated oxidative stress toward endothelium: a role for ferryl iron. Am J Physiol. 1998; 275: H1046-H1053.
17. Baron V, Muriel P. Role of glutathione, lipid peroxidation and antioxidants on acute bile-duct obstruction in the rat. Biochem Biophys Acta. 1999; 1472: 173-180.
18. Schumann RR, Leong SR, Flaggs GW, et al. Structure and function of lipopolysaccharide binding protein. Science. 1990; 249: 1429-1431.
19. Reynolds MA, Siow Y, Collet D, Klar E, Richardson JS, Vitale GC. The role of bile acid secretion in the hepatic response to operation and infection. Am Surg. 1995; 61: 469-474.
20. Lee CM, Stewart L, Way LW. Postcholecystectomy abdominal bile collections. Arch Surg. 2000; 135: 538-544.
21. Jaeschke J. Chemokines, neutrophils, and inflammatory liver injury. Shock. 1996; 6: 403-404.
22. Wang F, Wang LY, Wright D, Parmely MJ. Redox imbalance differentially inhibits lipopolysaccharide-induced macrophage activation in the mouse liver. Infect Immun. 1999; 67: 5409-5416.
23. Pachter HL, Liang HC, Hofstetter SR. Liver and biliary tract trauma. In: Feliciano DV, Moore EE, Mattox KL, eds. Trauma. 3rd ed. Stanford, CT: Appleton & Lange; 1996: 495.