Hemoglobin enhances the biological activity of synthetic and natural bacterial (endotoxic) virulence factors: A general principle

Medicinal Chemistry

Volumn 4, Issue 6, 2008, Pages 520-525

  Howe, Jörg ^a   Richter, Walter ^b   Hawkins, Lynn ^c   Rössle, Manfred ^d   Alexander, Christian ^a   Fournier, Karin ^e   Mach, Jean Pierre ^e   Waelli, Thierry ^f   Gorczynski, Reginald M ^g   Ulmer, Artur J ^a   Brade, Helmut ^a   Zamyatina, Alla ^h   Kosma, Paul ^h   Rietschel, Ernst Th ⁱ   Brandenburg, Klaus ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c EISAI RESEARCH INSTITUTE   (United States)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^e UNIVERSITY OF LAUSANNE   (Switzerland)

^f Clinique La Prairie   (Switzerland)

^g UNIVERSITY HEALTH NETWORK   (Canada)

^h UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

ⁱ POTSDAM INSTITUTE FOR CLIMATE IMPACT RESEARCH PIK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; ENDOTOXIN; HEMOGLOBIN; LIPID A; TUMOR NECROSIS FACTOR ALPHA; VIRULENCE FACTOR;

ARTICLE; BACTERIAL VIRULENCE; BIOLOGICAL ACTIVITY; CHLAMYDIA TRACHOMATIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY TEST; ENZYME ACTIVITY; ENZYME STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MONONUCLEAR CELL; NONHUMAN; PATHOGENICITY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

ANIMALS; CARBOHYDRATES; CYTOKINES; FREEZE FRACTURING; HEMOGLOBINS; HUMANS; LIPIDS; LIPOPOLYSACCHARIDES; MONOCYTES; SALMONELLA; SHEEP; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE; TUMOR NECROSIS FACTOR-ALPHA; VIRULENCE FACTORS; X-RAY DIFFRACTION;

EID: 57349157136     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340608786242089     Document Type: Article

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