SAM-pointed domain ETS factor mediates epithelial cell-intrinsic innate immune signaling during airway mucous metaplasia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 41, 2012, Pages 16630-16635

  Korfhagen, Thomas R ^a   Kitzmiller, Joseph ^a   Chen, Gang ^a   Sridharan, Anusha ^a   Haitchi, Hans Michael ^b   Hegde, Rashmi S ^a   Divanovic, Senad ^a   Karp, Christopher L ^a,c   Whitsett, Jeffrey A ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c BILL AND MELINDA GATES FOUNDATION   (United States)

Author keywords

Airway epithelium; Innate immunity

Indexed keywords

DOXYCYCLINE; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR ETS;

AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; EPITHELIUM CELL; GOBLET CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; INNATE IMMUNITY; LUNG; LUNG DISEASE; LUNG GAS EXCHANGE; METAPLASIA; MOUSE; MUCUS; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTI-BACTERIAL AGENTS; BLOTTING, WESTERN; DOXYCYCLINE; EPITHELIAL CELLS; GENE EXPRESSION; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-13; LIPOPOLYSACCHARIDES; LUNG DISEASES; METAPLASIA; MICE; MICROSCOPY, CONFOCAL; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-ETS; RESPIRATORY MUCOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHINOVIRUS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84867340544     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1208092109     Document Type: Article

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