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Volumn 2, Issue , 2012, Pages 174-183

Contrasting effects of IFNα on MHC class II expression in professional vs. nonprofessional APCs: Role of CIITA type IV promoter

Author keywords

CIITA promoter IV; IFN ; MHCII; Non professional antigen presenting cells

Indexed keywords

ALPHA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CIITA TYPE IV; UNCLASSIFIED DRUG;

EID: 84867310486     PISSN: None     EISSN: 22112839     Source Type: Journal    
DOI: 10.1016/j.rinim.2012.09.001     Document Type: Article
Times cited : (6)

References (77)
  • 2
    • 0025741031 scopus 로고
    • Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis
    • Christinck E.R., Luscher M.A., Barber B.H., Williams D.B. Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis. Nature 1991, 352:67-70.
    • (1991) Nature , vol.352 , pp. 67-70
    • Christinck, E.R.1    Luscher, M.A.2    Barber, B.H.3    Williams, D.B.4
  • 4
    • 0028142430 scopus 로고
    • Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA
    • Steimle V., Siegrist C.A., Mottet A., Lisowska-Grospierre B., Mach B. Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA. Science 1994, 265:106-109.
    • (1994) Science , vol.265 , pp. 106-109
    • Steimle, V.1    Siegrist, C.A.2    Mottet, A.3    Lisowska-Grospierre, B.4    Mach, B.5
  • 7
    • 0034533147 scopus 로고    scopus 로고
    • Statins as a newly recognized type of immunomodulator
    • Kwak B., Mulhaupt F., Myit S., Mach F. Statins as a newly recognized type of immunomodulator. Nature Medicine 2000, 6:1399-1402.
    • (2000) Nature Medicine , vol.6 , pp. 1399-1402
    • Kwak, B.1    Mulhaupt, F.2    Myit, S.3    Mach, F.4
  • 8
    • 0037408418 scopus 로고    scopus 로고
    • Normal human kidney HLA-DR-expressing renal microvascular endothelial cells: characterization, isolation, and regulation of MHC class II expression
    • Muczynski K.A., Ekle D.M., Coder D.M., Anderson S.K. Normal human kidney HLA-DR-expressing renal microvascular endothelial cells: characterization, isolation, and regulation of MHC class II expression. Journal of the American Society of Nephrology 2003, 14:1336-1348.
    • (2003) Journal of the American Society of Nephrology , vol.14 , pp. 1336-1348
    • Muczynski, K.A.1    Ekle, D.M.2    Coder, D.M.3    Anderson, S.K.4
  • 9
    • 0035400015 scopus 로고    scopus 로고
    • Constitutive expression of MHC class II genes in melanoma cell lines results from the transcription of class II transactivator abnormally initiated from its B Cell-specific promoter
    • Deffrennes V., Vedrenne J., Stolzenberg M.-C., Piskurich J., Barbieri G., Ting J.P., Charron D., Alcaide-Loridan C. Constitutive expression of MHC class II genes in melanoma cell lines results from the transcription of class II transactivator abnormally initiated from its B Cell-specific promoter. Journal of Immunology 2001, 167:98-106.
    • (2001) Journal of Immunology , vol.167 , pp. 98-106
    • Deffrennes, V.1    Vedrenne, J.2    Stolzenberg, M.-C.3    Piskurich, J.4    Barbieri, G.5    Ting, J.P.6    Charron, D.7    Alcaide-Loridan, C.8
  • 11
    • 0027145904 scopus 로고
    • Control of MHC class II gene expression in autoimmune, infectious, and neoplastic diseases
    • Guardiola J., Maffei A. Control of MHC class II gene expression in autoimmune, infectious, and neoplastic diseases. Critical Reviews in Immunology 1993, 13:247-268.
    • (1993) Critical Reviews in Immunology , vol.13 , pp. 247-268
    • Guardiola, J.1    Maffei, A.2
  • 12
    • 0036348187 scopus 로고    scopus 로고
    • Pathways of allorecognition: implications for transplantation tolerance
    • Game D.S., Lechler R.I. Pathways of allorecognition: implications for transplantation tolerance. Transplant Immunology 2002, 10:101-108.
    • (2002) Transplant Immunology , vol.10 , pp. 101-108
    • Game, D.S.1    Lechler, R.I.2
  • 14
    • 0036239887 scopus 로고    scopus 로고
    • Genetic control of MHC class II expression
    • Ting J.P., Trowsdale J. Genetic control of MHC class II expression. Cell 2002, 109(Suppl.):S21-S33.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Ting, J.P.1    Trowsdale, J.2
  • 15
    • 0030949011 scopus 로고    scopus 로고
    • Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA
    • Muhlethaler-Mottet A., Otten L.A., Steimle V., Mach B. Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA. EMBO Journal 1997, 16:2851-2860.
    • (1997) EMBO Journal , vol.16 , pp. 2851-2860
    • Muhlethaler-Mottet, A.1    Otten, L.A.2    Steimle, V.3    Mach, B.4
  • 16
    • 0037086608 scopus 로고    scopus 로고
    • Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation
    • Masternak K., Reith W. Promoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activation. EMBO Journal 2002, 21:1379-1388.
    • (2002) EMBO Journal , vol.21 , pp. 1379-1388
    • Masternak, K.1    Reith, W.2
  • 18
    • 0035920551 scopus 로고    scopus 로고
    • The pIV-otal class II transactivator promoter regulates major histocompatibility complex class II expression in the thymus
    • Honey K., Rudensky A. The pIV-otal class II transactivator promoter regulates major histocompatibility complex class II expression in the thymus. Journal of Experimental Medicine 2001, 194:F15-F18.
    • (2001) Journal of Experimental Medicine , vol.194
    • Honey, K.1    Rudensky, A.2
  • 19
    • 33748772259 scopus 로고    scopus 로고
    • Positive regulatory domain I-binding factor 1 mediates repression of the MHC class II transactivator (CIITA) type IV promoter
    • Chen H., Gilbert C.A., Hudson J.A., Bolick S.C., Wright K.L., Piskurich J.F. Positive regulatory domain I-binding factor 1 mediates repression of the MHC class II transactivator (CIITA) type IV promoter. Molecular Immunology 2007, 44:1461-1470.
    • (2007) Molecular Immunology , vol.44 , pp. 1461-1470
    • Chen, H.1    Gilbert, C.A.2    Hudson, J.A.3    Bolick, S.C.4    Wright, K.L.5    Piskurich, J.F.6
  • 21
    • 0034655297 scopus 로고    scopus 로고
    • Methylation of class II trans-activator promoter IV:a novel mechanism of MHC class II gene control
    • Morris A.C., Spangler W.E., Boss J.M. Methylation of class II trans-activator promoter IV:a novel mechanism of MHC class II gene control. Journal of Immunology 2000, 164:4143-4149.
    • (2000) Journal of Immunology , vol.164 , pp. 4143-4149
    • Morris, A.C.1    Spangler, W.E.2    Boss, J.M.3
  • 22
    • 0031065145 scopus 로고    scopus 로고
    • TGF-beta attenuates the class II transactivator and reveals an accessory pathway of IFN-gamma action
    • Nandan D., Reiner N.E. TGF-beta attenuates the class II transactivator and reveals an accessory pathway of IFN-gamma action. Journal of Immunology 1997, 158:1095-1101.
    • (1997) Journal of Immunology , vol.158 , pp. 1095-1101
    • Nandan, D.1    Reiner, N.E.2
  • 23
    • 0031906211 scopus 로고    scopus 로고
    • Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene
    • Piskurich J.F., Wang Y., Linhoff M.W., White L.C., Ting J.P. Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene. Journal of Immunology 1998, 160:233-240.
    • (1998) Journal of Immunology , vol.160 , pp. 233-240
    • Piskurich, J.F.1    Wang, Y.2    Linhoff, M.W.3    White, L.C.4    Ting, J.P.5
  • 24
    • 33845947044 scopus 로고    scopus 로고
    • Inhibition of MHC class II gene expression in uveal melanoma cells is due to methylation of the CIITA gene or an upstream activator
    • Radosevich M., Jager M., Ono S.J. Inhibition of MHC class II gene expression in uveal melanoma cells is due to methylation of the CIITA gene or an upstream activator. Experimental and Molecular Pathology 2007, 82:68-76.
    • (2007) Experimental and Molecular Pathology , vol.82 , pp. 68-76
    • Radosevich, M.1    Jager, M.2    Ono, S.J.3
  • 26
    • 0038305942 scopus 로고    scopus 로고
    • Class II transactivator (CIITA) deficiency in tumor cells: complicated mechanisms or not
    • van den Elsen P.J., van der Stoep N., Yazawa T. Class II transactivator (CIITA) deficiency in tumor cells: complicated mechanisms or not. American Journal of Pathology 2003, 163:373-376.
    • (2003) American Journal of Pathology , vol.163 , pp. 373-376
    • van den Elsen, P.J.1    van der Stoep, N.2    Yazawa, T.3
  • 27
    • 0035920552 scopus 로고    scopus 로고
    • Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene
    • Waldburger J.-M., Suter T., Fontana A., Acha-Orbea H., Reith W. Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene. Journal of Experimental Medicine 2001, 194:393-406.
    • (2001) Journal of Experimental Medicine , vol.194 , pp. 393-406
    • Waldburger, J.-M.1    Suter, T.2    Fontana, A.3    Acha-Orbea, H.4    Reith, W.5
  • 30
    • 0028842529 scopus 로고
    • Interferon (IFN) beta acts downstream of IFN-gamma-induced class II transactivator messenger RNA accumulation to block major histocompatibility complex class II gene expression and requires the 48-kD DNA-binding protein, ISGF3-gamma
    • Lu H.T., Riley J.L., Babcock G.T., Huston M., Stark G.R., Boss J.M., Ransohoff R.M. Interferon (IFN) beta acts downstream of IFN-gamma-induced class II transactivator messenger RNA accumulation to block major histocompatibility complex class II gene expression and requires the 48-kD DNA-binding protein, ISGF3-gamma. Journal of Experimental Medicine 1995, 182:1517-1525.
    • (1995) Journal of Experimental Medicine , vol.182 , pp. 1517-1525
    • Lu, H.T.1    Riley, J.L.2    Babcock, G.T.3    Huston, M.4    Stark, G.R.5    Boss, J.M.6    Ransohoff, R.M.7
  • 31
    • 0037061736 scopus 로고    scopus 로고
    • Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells
    • Huang S., Bucana C.D., Van Arsdall M., Fidler I.J. Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells. Oncogene 2002, 21:2504-2512.
    • (2002) Oncogene , vol.21 , pp. 2504-2512
    • Huang, S.1    Bucana, C.D.2    Van Arsdall, M.3    Fidler, I.J.4
  • 34
    • 0037213718 scopus 로고    scopus 로고
    • The IRF-2 DNA binding domain facilitates the activation of the class II transactivator (CIITA) type IV promoter by IRF-1
    • Xi H., Blanck G. The IRF-2 DNA binding domain facilitates the activation of the class II transactivator (CIITA) type IV promoter by IRF-1. Molecular Immunology 2003, 39:677-684.
    • (2003) Molecular Immunology , vol.39 , pp. 677-684
    • Xi, H.1    Blanck, G.2
  • 36
    • 0024576553 scopus 로고
    • In situ hybridization analysis of interstitial C-heterochromatin in marker chromosomes of two human melanomas
    • Doneda L., Ginelli E., Agresti A., Larizza L. In situ hybridization analysis of interstitial C-heterochromatin in marker chromosomes of two human melanomas. Cancer Research 1989, 49:433-438.
    • (1989) Cancer Research , vol.49 , pp. 433-438
    • Doneda, L.1    Ginelli, E.2    Agresti, A.3    Larizza, L.4
  • 37
    • 0023125207 scopus 로고
    • Gangliosides of human melanoma: altered expression in vivo and in vitro
    • Tsuchida T., Ravindranath M.H., Saxton R.E., Irie R.F. Gangliosides of human melanoma: altered expression in vivo and in vitro. Cancer Research 1987, 47:1278-1281.
    • (1987) Cancer Research , vol.47 , pp. 1278-1281
    • Tsuchida, T.1    Ravindranath, M.H.2    Saxton, R.E.3    Irie, R.F.4
  • 40
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 42
    • 1542619547 scopus 로고    scopus 로고
    • Regulation of MHC class II expression in glioma cells by class II transactivator (CIITA)
    • Takamura Y., Ikeda H., Kanaseki T., Toyota M., Tokino T., Imai K., Houkin K., Sato N. Regulation of MHC class II expression in glioma cells by class II transactivator (CIITA). Glia 2004, 45:392-405.
    • (2004) Glia , vol.45 , pp. 392-405
    • Takamura, Y.1    Ikeda, H.2    Kanaseki, T.3    Toyota, M.4    Tokino, T.5    Imai, K.6    Houkin, K.7    Sato, N.8
  • 43
    • 0033959383 scopus 로고    scopus 로고
    • CD4(+) T cells kill HLA-class-II-antigen-positive melanoma cells presenting peptide in vitro
    • Brady M.S., Lee F., Petrie H., Eckels D.D., Lee J.S. CD4(+) T cells kill HLA-class-II-antigen-positive melanoma cells presenting peptide in vitro. Cancer Immunology, Immunotherapy 2000, 48:621-626.
    • (2000) Cancer Immunology, Immunotherapy , vol.48 , pp. 621-626
    • Brady, M.S.1    Lee, F.2    Petrie, H.3    Eckels, D.D.4    Lee, J.S.5
  • 44
    • 0035542991 scopus 로고    scopus 로고
    • Malignant glioma cells use MHC class II transactivator (CIITA) promoters III and IV to direct IFN-gamma-inducible CIITA expression and can function as nonprofessional antigen presenting cells in endocytic processing and CD4(+) T-cell activation
    • Soos J.M., Krieger J.I., Stuve O., King C.L., Patarroyo J.C., Aldape K., Wosik K., Slavin A.J., Nelson P.A., Antel J.P., Zamvil S.S. Malignant glioma cells use MHC class II transactivator (CIITA) promoters III and IV to direct IFN-gamma-inducible CIITA expression and can function as nonprofessional antigen presenting cells in endocytic processing and CD4(+) T-cell activation. Glia 2001, 36:391-405.
    • (2001) Glia , vol.36 , pp. 391-405
    • Soos, J.M.1    Krieger, J.I.2    Stuve, O.3    King, C.L.4    Patarroyo, J.C.5    Aldape, K.6    Wosik, K.7    Slavin, A.J.8    Nelson, P.A.9    Antel, J.P.10    Zamvil, S.S.11
  • 46
    • 0032908350 scopus 로고    scopus 로고
    • Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta
    • Piskurich J.F., Linhoff M.W., Wang Y., Ting J.P. Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta. Molecular and Cellular Biology 1999, 19:431-440.
    • (1999) Molecular and Cellular Biology , vol.19 , pp. 431-440
    • Piskurich, J.F.1    Linhoff, M.W.2    Wang, Y.3    Ting, J.P.4
  • 47
    • 0031821617 scopus 로고    scopus 로고
    • Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway
    • Darnell Jr J.E. Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway. Journal of Interferon, Cytokine and Mediator Research 1998, 18:549-554.
    • (1998) Journal of Interferon, Cytokine and Mediator Research , vol.18 , pp. 549-554
    • Darnell Jr, J.E.1
  • 48
    • 0036595049 scopus 로고    scopus 로고
    • Suppressors of cytokine signalling (SOCS) in the immune system
    • Alexander W.S. Suppressors of cytokine signalling (SOCS) in the immune system. Nature Reviews Immunology 2002, 2:410-416.
    • (2002) Nature Reviews Immunology , vol.2 , pp. 410-416
    • Alexander, W.S.1
  • 50
    • 0035865207 scopus 로고    scopus 로고
    • IFN-{{gamma}} regulation of class II transactivator promoter IV in macrophages and microglia: involvement of the suppressors of cytokine signaling-1 protein
    • O'Keefe G.M., Nguyen V.T., Ping Tang L., Benveniste E.N. IFN-{{gamma}} regulation of class II transactivator promoter IV in macrophages and microglia: involvement of the suppressors of cytokine signaling-1 protein. Journal of Immunology 2001, 166:2260-2269.
    • (2001) Journal of Immunology , vol.166 , pp. 2260-2269
    • O'Keefe, G.M.1    Nguyen, V.T.2    Ping Tang, L.3    Benveniste, E.N.4
  • 51
    • 0035863734 scopus 로고    scopus 로고
    • High level class II trans-activator induction does not occur with transient activation of the IFN-{{gamma}} signaling pathway
    • Eason D.D., Blanck G. High level class II trans-activator induction does not occur with transient activation of the IFN-{{gamma}} signaling pathway. Journal of Immunology 2001, 166:1041-1048.
    • (2001) Journal of Immunology , vol.166 , pp. 1041-1048
    • Eason, D.D.1    Blanck, G.2
  • 53
    • 0031570834 scopus 로고    scopus 로고
    • Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages
    • Lehtonen A., Matikainen S., Julkunen I. Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages. Journal of Immunology 1997, 159:794-803.
    • (1997) Journal of Immunology , vol.159 , pp. 794-803
    • Lehtonen, A.1    Matikainen, S.2    Julkunen, I.3
  • 54
    • 0038708174 scopus 로고    scopus 로고
    • Improving survival in patients with high-risk and metastatic melanoma: immunotherapy leads the way
    • Agarwala S. Improving survival in patients with high-risk and metastatic melanoma: immunotherapy leads the way. American Journal of Clinical Dermatology 2003, 4:333-346.
    • (2003) American Journal of Clinical Dermatology , vol.4 , pp. 333-346
    • Agarwala, S.1
  • 55
    • 0028041568 scopus 로고
    • Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes
    • Chang C.H., Fontes J.D., Peterlin M., Flavell R.A. Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes. Journal of Experimental Medicine 1994, 180:1367-1374.
    • (1994) Journal of Experimental Medicine , vol.180 , pp. 1367-1374
    • Chang, C.H.1    Fontes, J.D.2    Peterlin, M.3    Flavell, R.A.4
  • 56
    • 0036274018 scopus 로고    scopus 로고
    • Kinetics of a gamma interferon response: expression and assembly of CIITA promoter IV and inhibition by methylation
    • Morris A.C., Beresford G.W., Mooney M.R., Boss J.M. Kinetics of a gamma interferon response: expression and assembly of CIITA promoter IV and inhibition by methylation. Molecular and Cellular Biology 2002, 22:4781-4791.
    • (2002) Molecular and Cellular Biology , vol.22 , pp. 4781-4791
    • Morris, A.C.1    Beresford, G.W.2    Mooney, M.R.3    Boss, J.M.4
  • 57
    • 0036681840 scopus 로고    scopus 로고
    • Regulation of class II MHC expression in APCs: roles of types I, III, and IV class II transactivator
    • Pai R.K., Askew D., Boom W.H., Harding C.V. Regulation of class II MHC expression in APCs: roles of types I, III, and IV class II transactivator. Journal of Immunology 2002, 169:1326-1333.
    • (2002) Journal of Immunology , vol.169 , pp. 1326-1333
    • Pai, R.K.1    Askew, D.2    Boom, W.H.3    Harding, C.V.4
  • 58
    • 33747055643 scopus 로고    scopus 로고
    • Epigenetic regulation of MHC-II and CIITA genes
    • Wright K.L., Ting J.P. Epigenetic regulation of MHC-II and CIITA genes. Trends inImmunology 2006, 27:405-412.
    • (2006) Trends inImmunology , vol.27 , pp. 405-412
    • Wright, K.L.1    Ting, J.P.2
  • 59
    • 0034515268 scopus 로고    scopus 로고
    • Immune response in Stat2 knockout mice
    • Park C., Li S., Cha E., Schindler C. Immune response in Stat2 knockout mice. Immunity 2000, 13:795-804.
    • (2000) Immunity , vol.13 , pp. 795-804
    • Park, C.1    Li, S.2    Cha, E.3    Schindler, C.4
  • 61
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I- and type-II-interferon-mediated signalling
    • Platanias L.C. Mechanisms of type-I- and type-II-interferon-mediated signalling. Nature Reviews Immunology 2005, 5:375-386.
    • (2005) Nature Reviews Immunology , vol.5 , pp. 375-386
    • Platanias, L.C.1
  • 62
    • 0026019924 scopus 로고
    • Cytoplasmic activation of GAF, an IFN-gamma-regulated DNA-binding factor
    • Decker T., Lew D.J., Mirkovitch J., Darnell Jr J.E. Cytoplasmic activation of GAF, an IFN-gamma-regulated DNA-binding factor. EMBO Journal 1991, 10:927-932.
    • (1991) EMBO Journal , vol.10 , pp. 927-932
    • Decker, T.1    Lew, D.J.2    Mirkovitch, J.3    Darnell Jr, J.E.4
  • 63
    • 0027090310 scopus 로고
    • Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein
    • Shuai K., Schindler C., Prezioso V.R., Darnell Jr J.E. Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein. Science 1992, 258:1808-1812.
    • (1992) Science , vol.258 , pp. 1808-1812
    • Shuai, K.1    Schindler, C.2    Prezioso, V.R.3    Darnell Jr, J.E.4
  • 64
    • 0026910905 scopus 로고
    • Constitutive production of interferon-alpha 2 by a human B-lymphoblastoid cell line
    • Adolf G.R., Pieler C., Maurer-Fogy I. Constitutive production of interferon-alpha 2 by a human B-lymphoblastoid cell line. Journal of Interferon Research 1992, 12:275-280.
    • (1992) Journal of Interferon Research , vol.12 , pp. 275-280
    • Adolf, G.R.1    Pieler, C.2    Maurer-Fogy, I.3
  • 65
    • 37849189202 scopus 로고    scopus 로고
    • Constitutive and IFN[gamma]-induced activation of MHC2TA promoter type III in human melanoma cell lines is governed by separate regulatory elements within the PIII upstream regulatory region
    • van der Stoep N, Quinten E., Alblas G., Plancke A., van Eggermond M.C.J.A., Holling T.M., van den Elsen P.J. Constitutive and IFN[gamma]-induced activation of MHC2TA promoter type III in human melanoma cell lines is governed by separate regulatory elements within the PIII upstream regulatory region. Molecular Immunology 2007, 44:2036-2046.
    • (2007) Molecular Immunology , vol.44 , pp. 2036-2046
    • van der Stoep, N.1    Quinten, E.2    Alblas, G.3    Plancke, A.4    van Eggermond, M.C.J.A.5    Holling, T.M.6    van den Elsen, P.J.7
  • 66
    • 33947583705 scopus 로고    scopus 로고
    • STAT activation and differential complex formation dictate selectivity of interferon responses
    • Wesoly J., Szweykowska-Kulinska Z., Bluyssen H.A. STAT activation and differential complex formation dictate selectivity of interferon responses. Acta Biochimica Polonica 2007, 54:27-38.
    • (2007) Acta Biochimica Polonica , vol.54 , pp. 27-38
    • Wesoly, J.1    Szweykowska-Kulinska, Z.2    Bluyssen, H.A.3
  • 67
    • 0141958148 scopus 로고    scopus 로고
    • IFN-{gamma}-induced MHC class II expression: transactivation of class II transactivator promoter IV by IFN regulatory factor-1 is regulated by protein kinase C-{alpha}
    • Giroux M., Schmidt M., Descoteaux A. IFN-{gamma}-induced MHC class II expression: transactivation of class II transactivator promoter IV by IFN regulatory factor-1 is regulated by protein kinase C-{alpha}. Journal ofImmunology 2003, 171:4187-4194.
    • (2003) Journal ofImmunology , vol.171 , pp. 4187-4194
    • Giroux, M.1    Schmidt, M.2    Descoteaux, A.3
  • 68
    • 34247107684 scopus 로고    scopus 로고
    • IFN-{alpha}-induced signal transduction, gene expression, and antitumor activity of immune effector cells are negatively regulated by suppressor of cytokine signaling proteins
    • Zimmerer J.M., Lesinski G.B., Kondadasula S.V., Karpa V.I., Lehman A., RayChaudhury A., Becknell B., Carson III W.E. IFN-{alpha}-induced signal transduction, gene expression, and antitumor activity of immune effector cells are negatively regulated by suppressor of cytokine signaling proteins. Journal ofImmunology 2007, 178:4832-4845.
    • (2007) Journal ofImmunology , vol.178 , pp. 4832-4845
    • Zimmerer, J.M.1    Lesinski, G.B.2    Kondadasula, S.V.3    Karpa, V.I.4    Lehman, A.5    RayChaudhury, A.6    Becknell, B.7    Carson III, W.E.8
  • 70
    • 0032567353 scopus 로고    scopus 로고
    • The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities
    • Song M.M., Shuai K. The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities. Journal of Biological Chemistry 1998, 273:35056-35062.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 35056-35062
    • Song, M.M.1    Shuai, K.2
  • 73
    • 43949158868 scopus 로고
    • Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes
    • Nickoloff B.J., Turka L.A. Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes. Immunology Today 1994, 15:464-469.
    • (1994) Immunology Today , vol.15 , pp. 464-469
    • Nickoloff, B.J.1    Turka, L.A.2
  • 74
    • 79960699389 scopus 로고    scopus 로고
    • Immunological function of the endothelial cell within the setting of organ transplantation
    • Taflin C, Charron D, Glotz D, Mooney N. Immunological function of the endothelial cell within the setting of organ transplantation. Immunology Letters 2011: 139, 1-6.
    • (2011) Immunology Letters , vol.139 , pp. 1-6
    • Taflin, C.1    Charron, D.2    Glotz, D.3    Mooney, N.4


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