(-)-Epigallocatechin-3-Gallate Induces Non-Apoptotic Cell Death in Human Cancer Cells via ROS-Mediated Lysosomal Membrane Permeabilization

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Zhang, Yin ^a,b   Yang, Nai Di ^b   Zhou, Fan ^a   Shen, Ting ^a   Duan, Ting ^a   Zhou, Jing ^b   Shi, Yin ^b   Zhu, Xin Qiang ^a   Shen, Han Ming ^b,c,d  

^a ZHEJIANG UNIVERSITY   (China)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CASPASE 3; EPIGALLOCATECHIN GALLATE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ACIDIFICATION; ARTICLE; AUTOPHAGY; CANCER CELL; CELL DEATH; CELL PERMEABILIZATION; CELL VACUOLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; LYSOSOME MEMBRANE; MEMBRANE PERMEABILITY; MOLECULAR DYNAMICS; MORPHOLOGY; PROTEIN CLEAVAGE; PROTEIN DEGRADATION;

APOPTOSIS; BLOTTING, WESTERN; CATECHIN; CELL SURVIVAL; HEP G2 CELLS; HUMANS; INTRACELLULAR MEMBRANES; LYSOSOMES; REACTIVE OXYGEN SPECIES;

EID: 84867289163     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046749     Document Type: Article

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