Lipid raft-targeted Akt promotes axonal branching and growth cone expansion via mTOR and Rac1, respectively

Journal of Neuroscience Research

Volumn 87, Issue 14, 2009, Pages 3033-3042

  Grider, M H ^a,b   Park, D ^a   Spencer, D M ^a   Shine, H D ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b CENTER FOR CELL AND GENE THERAPY   (United States)

Author keywords

Akt; Axonal branching; Constitutively active Akt (CA Akt); Growth cone expansion; Lipid rafts; Localized signaling; Rho GTPases

Indexed keywords

CALCIUM PHOSPHATE; ENHANCED GREEN FLUORESCENT PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; RAC1 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOLISTIC TRANSFORMATION; CELL EXPANSION; CELL STRUCTURE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; GROWTH CONE; LIPID RAFT; MOLECULAR DYNAMICS; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL CORD NERVE CELL; SPINAL GANGLION;

ANIMALS; AXONS; BLOTTING, WESTERN; CHICK EMBRYO; GROWTH CONES; IMMUNOHISTOCHEMISTRY; MEMBRANE MICRODOMAINS; MICROSCOPY, CONFOCAL; NERVE REGENERATION; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RAC1 GTP-BINDING PROTEIN; TRANSDUCTION, GENETIC;

EID: 70449473508     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22140     Document Type: Article

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