Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein

Journal of Biological Chemistry

Volumn 287, Issue 41, 2012, Pages 34583-34595

  Darmellah, Amaria ^a   Rayah, Amel ^a   Auger, Rodolphe ^a   Cuif, Marie Hélène ^b   Prigent, Magali ^b   Arpin, Monique ^c   Alcover, Andres ^a   Delarasse, Cécile ^d   Kanellopoulos, Jean M ^a  

^a CNRS   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c INSTITUT CURIE   (France)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEINS; DOWN-REGULATION; ECTODOMAIN; NEURAL CELLS; PHARMACOLOGICAL INHIBITORS; PROTEOLYTIC PROCESSING; SECRETASES;

CELL MEMBRANES; ENZYMES; GLYCOPROTEINS; PHOSPHORYLATION;

PROTEINS;

ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; EZRIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MOESIN; PHOSPHATIDYLINOSITOL 3 KINASE; PURINERGIC P2X7 RECEPTOR; RADIXIN; RHO KINASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; DOWNSTREAM PROCESSING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; REGULATORY MECHANISM;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE, TUMOR; CYTOSKELETAL PROTEINS; HEK293 CELLS; HUMANS; MEMBRANE PROTEINS; MICE; MICROFILAMENT PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEOLYSIS; RECEPTORS, PURINERGIC P2X7; RHO-ASSOCIATED KINASES;

EID: 84867258411     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.400010     Document Type: Article

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