Using gene-network landscape to dissect genotype effects of TCF7L2 genetic variant on diabetes and cardiovascular risk

Physiological Genomics

Volumn 44, Issue 19, 2012, Pages 903-914

  Vaquero, Andre R ^a   Ferreira, Noely E ^a   Omae, Samantha V ^a   Rodrigues, Mariliza V ^a   Teixeira, Samantha K ^a   Krieger, Jose E ^a   Pereira, Alexandre C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Correlation networks; Differential coexpression; Differential expression; Type 2 diabetes mellitus

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; E1A ASSOCIATED P300 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR 7 LIKE 2; TUMOR NECROSIS FACTOR ALPHA;

AGED; ALLELE; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; CORRELATION ANALYSIS; DISEASE COURSE; FEMALE; GENE; GENE EXPRESSION; GENE INTERACTION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RXR ALPHA GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOOTH MUSCLE FIBER; STATISTICAL SIGNIFICANCE; TCF7L2 GENE; VASCULAR SMOOTH MUSCLE; WILD TYPE;

BRAZIL; CARDIOVASCULAR DISEASES; CORONARY ARTERY BYPASS; DIABETES MELLITUS, TYPE 2; DNA PRIMERS; GENE REGULATORY NETWORKS; GENOTYPE; HUMANS; MUSCLE, SMOOTH, VASCULAR; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN ISOFORMS; REAL-TIME POLYMERASE CHAIN REACTION; RETINOID X RECEPTOR ALPHA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK FACTORS; TRANSCRIPTION FACTOR 7-LIKE 2 PROTEIN;

EID: 84867178393     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00030.2012     Document Type: Article

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