Getting biological about the genetics of diabetes

Nature Medicine

Volumn 16, Issue 4, 2010, Pages 388-391

  Newgard, Christopher B ^a   Attie, Alan D ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; ACYL COENZYME A DESATURASE; ALANINE GLYOXYLATE AMINOTRANSFERASE; ARGINASE 1; HYPOXIA INDUCIBLE FACTOR 1BETA; LEPTIN; LEPTIN RECEPTOR; LIVER TRIACYLGLYCEROL LIPASE; MESSENGER RNA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP);

CHROMOSOME 1; DIABETES MELLITUS; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN GENETICS; HUMAN GENOME; MEDICAL GENETICS; METABOLOMICS; MICROARRAY ANALYSIS; NONHUMAN; NOTE; OBESITY; PARABIOSIS; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROCESSING;

ANIMALS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; METABOLOMICS; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE;

EID: 77950540076     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm0410-388     Document Type: Note

References (42)

1. Tinkelenberg, A.H. et al. J. Biol. Chem. 275, 40667-40670 (2000).
2. O'Rahilly, S. Nature 462, 307-314 (2009).
3. Zeggini, E. et al. Nat. Genet. 40, 638-645 (2008).
4. Prokopenko, I., McCarthy, M.I. & Lindgren, C.M. Trends Genet. 24, 613-621 (2008).
5. Romeo, S. et al. Nat. Genet. 40, 1461-1465 (2008).
6. Tong, Y. et al. BMC Med. Genet. 10, 15 (2009).
7. Cohen, J.C. et al. Science 305, 869-872 (2004).
8. Kathiresan, S. et al. Nat. Genet. 41, 56-65 (2009).
9. Romeo, S. et al. Nat. Genet. 39, 513-516 (2007).
10. Lu, D. et al. Nature 371, 799-802 (1994).
11. Michaud, E.J. et al. Proc. Natl. Acad. Sci. USA 91, 2562-2566 (1994).
12. Bultman, S.J., Michaud, E.J. & Woychik, R.P. Cell 71, 1195-1204 (1992).
13. Loos, R.J. et al. Nat. Genet. 40, 768-775 (2008).
14. Coleman, D.L. Diabetologia 14, 141-148 (1978).
15. Zhang, Y. et al. Nature 372, 425-432 (1994).
16. Tartaglia, L.A. et al. Cell 83, 1263-1271 (1995).
17. Farooqi, S. & O'Rahilly, S. Endocr. Rev. 27, 710-718 (2006).
18. Farooqi, I.S. & O'Rahilly, S. Am. J. Clin. Nutr. 89, 980S-984S (2009).
19. Talbot, C.J. et al. Nat. Genet. 21, 305-308 (1999).
20. Chesler, E.J. et al. Mamm. Genome 19, 382-389 (2008).
21. Bain, J.R. et al. Diabetes 58, 2429-2443 (2009).
22. Yang, Q. et al. Nature 436, 356-362 (2005).
23. Graham, T.E. et al. N. Engl. J. Med. 354, 2552-2563 (2006).
24. Gunton, J.E. et al. Cell 122, 337-349 (2005).
25. Mootha, V.K. et al. Nat. Genet. 34, 267-273 (2003).
26. Patti, M.E. et al. Proc. Natl. Acad. Sci. USA 100, 8466-8471 (2003).
27. Koves, T.R. et al. Cell Metab. 7, 45-56 (2008).
28. Cao, H. et al. Cell 134, 933-944 (2008).
29. Gillum, M.P. et al. Cell 135, 813-824 (2008).
30. Kirchner, H. et al. Nat. Med. 15, 741-745 (2009).
31. Newgard, C.B. et al. Cell Metab. 9, 311-326 (2009).
32. Huffman, K.M. et al. Diabetes Care 32, 1678-1683 (2009).
33. Schadt, E.E. Nature 461, 218-223 (2009).
34. Schadt, E.E. et al. PLoS Biol. 6, e107 (2008).
35. Choi, Y. & Kendziorski, C. Bioinformatics 25, 2780-2786 (2009).
36. Lai, Y., Wu, B., Chen, L. & Zhao, H. Bioinformatics 20, 3146-3155 (2004).
37. Zhang, B. & Horvath, S. Stat. Appl. Genet. Mol. Biol. 4, Article17 (2005).
38. Keller, M.P. et al. Genome Res. 18, 706-716 (2008).
39. Ferrara, C.T. et al. PLoS Genet. 4, e1000034 (2008).
40. Chaibub Neto, E., Ferrara, C.T., Attie, A.D. & Yandell, B.S. Genetics 179, 1089-1100 (2008).
41. Dumas, M.E. et al. Nat. Genet. 39, 666-672 (2007).
42. Gieger, C. et al. PLoS Genet. 4, e1000282 (2008).