Use of engineered bone marrow stem cells to deliver brain derived neurotrophic factor under the control of a tetracycline sensitive response element in experimental allergic encephalomyelitis

Journal of Neuroimmunology

Volumn 252, Issue 1-2, 2012, Pages 1-15

  Makar, Tapas K ^a,b,c   Nimmagadda, Vamshi K C ^a,c   Patibandla, Gopi K ^c   Le, Toby ^c   Judge, Susan I V ^a,b,c   Trisler, David ^a,b,c   Bever, Christopher T ^a,b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b VA Multiple Sclerosis Center of Excellence East   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Brain derived neurotrophic factor; CD34+ stem cells; Experimental allergic encephalomyelitis; Multiple sclerosis; Neuroprotection

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DOXYCYCLINE; GLUTAMATE DECARBOXYLASE 67; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; SIRTUIN 1;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DERIVED NEUROTROPHIC FACTOR GENE; BRAIN HOMOGENATE; CELL ENGINEERING; CONTROLLED STUDY; DISEASE SEVERITY; DNA RESPONSIVE ELEMENT; FEMALE; GENE; GENE DELIVERY SYSTEM; GENE EXPRESSION; HELA CELL; HEMATOPOIETIC STEM CELL; HISTOLOGY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD; TETRACYCLINE SENSITIVE RESPONSE ELEMENT;

ANIMALS; BONE MARROW TRANSPLANTATION; BRAIN-DERIVED NEUROTROPHIC FACTOR; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENETIC ENGINEERING; GENETIC VECTORS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; REAL-TIME POLYMERASE CHAIN REACTION; RESPONSE ELEMENTS; SPINAL CORD; STEM CELL TRANSPLANTATION; TETRACYCLINE;

EID: 84867139762     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2012.07.005     Document Type: Article

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