Insulators coupled to a minimal bidirectional tet cassette for tight regulation of rAAV-mediated gene transfer in the mammalian brain

Gene Therapy

Volumn 8, Issue 22, 2001, Pages 1675-1681

  Fitzsimons, H L ^a   McKenzie, J M ^a   During, M J ^a,b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Autoregulatory; CNS; Gene therapy; Insulators; rAAV; Tetracycline transactivator

Indexed keywords

DOXYCYCLINE; TRANSACTIVATOR PROTEIN; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOREGULATION; BRAIN; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; GENE CASSETTE; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; HUMAN; HUMAN CELL; MAMMAL; MOUSE; NONHUMAN; PHYSICAL DISEASE; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; TOXICITY; TRANSGENE; TRANSGENIC ANIMAL; VIRUS LOAD; VIRUS PURIFICATION; VIRUS RECOMBINANT;

ANIMALS; ANTI-BACTERIAL AGENTS; BRAIN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DEPENDOVIRUS; DOXYCYCLINE; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; LUCIFERASES; LUMINESCENT PROTEINS; MALE; RATS; RATS, WISTAR; TRANS-ACTIVATORS;

ADENO-ASSOCIATED VIRUS; ANIMALIA; MAMMALIA; MUS MUSCULUS;

EID: 0035666134     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301582     Document Type: Article

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