-
1
-
-
0033569516
-
Pharmacogenomics: translating functional genomics into rational therapeutics
-
Evans, W.E. and Relling, M.V. (1999) Pharmacogenomics: translating functional genomics into rational therapeutics. Science, 286, 487-491.
-
(1999)
Science
, vol.286
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
2
-
-
4344574336
-
Pharmacogenetics-five decades of therapeutic lessons from genetic diversity
-
Meyer, U.A. (2004) Pharmacogenetics-five decades of therapeutic lessons from genetic diversity. Nat. Rev. Genet., 5, 669-676.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 669-676
-
-
Meyer, U.A.1
-
3
-
-
84864363160
-
Pharmacogenetics and pharmacogenomics: role of mutational analysis in anti-cancer targeted therapy
-
Savonarola, A., Palmirotta, R., Guadagni, F. and Silvestris, F. (2012) Pharmacogenetics and pharmacogenomics: role of mutational analysis in anti-cancer targeted therapy. Pharmacogenomics J, 12, 277-286.
-
(2012)
Pharmacogenomics J
, vol.12
, pp. 277-286
-
-
Savonarola, A.1
Palmirotta, R.2
Guadagni, F.3
Silvestris, F.4
-
4
-
-
84857715227
-
Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation
-
Ong, F.S., Deignan, J.L., Kuo, J.Z., Bernstein, K.E., Rotter, J.I., Grody, W.W. and Das, K. (2012) Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation. Pharmacogenomics, 13, 465-475.
-
(2012)
Pharmacogenomics
, vol.13
, pp. 465-475
-
-
Ong, F.S.1
Deignan, J.L.2
Kuo, J.Z.3
Bernstein, K.E.4
Rotter, J.I.5
Grody, W.W.6
Das, K.7
-
5
-
-
0032522873
-
Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies
-
Lazarou, J., Pomeranz, B.H. and Corey, P.N. (1998) Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA, 279, 1200-1205.
-
(1998)
JAMA
, vol.279
, pp. 1200-1205
-
-
Lazarou, J.1
Pomeranz, B.H.2
Corey, P.N.3
-
6
-
-
0842263891
-
Adverse drug reactions: role of pharmacogenomics
-
Severino, G. and Del Zompo, M. (2004) Adverse drug reactions: role of pharmacogenomics. Pharmacol. Res., 49, 363-373.
-
(2004)
Pharmacol. Res.
, vol.49
, pp. 363-373
-
-
Severino, G.1
Del Zompo, M.2
-
7
-
-
22844448777
-
Priorities and standards in pharmacogenetic research
-
Need, A.C., Motulsky, A.G. and Goldstein, D.B. (2005) Priorities and standards in pharmacogenetic research. Nat. Genet., 37, 671-681.
-
(2005)
Nat. Genet.
, vol.37
, pp. 671-681
-
-
Need, A.C.1
Motulsky, A.G.2
Goldstein, D.B.3
-
8
-
-
4244183558
-
The danger hypothesis-potential role in idiosyncratic drug reactions
-
Pirmohamed, M., Naisbitt, D.J., Gordon, F. and Park, B.K. (2002) The danger hypothesis-potential role in idiosyncratic drug reactions. Toxicology, 181-182, 55-63.
-
(2002)
Toxicology, 181-182
, pp. 55-63
-
-
Pirmohamed, M.1
Naisbitt, D.J.2
Gordon, F.3
Park, B.K.4
-
9
-
-
0035369825
-
Genetic susceptibility to adverse drug reactions
-
Pirmohamed, M. and Park, B.K. (2001) Genetic susceptibility to adverse drug reactions. Trends Pharmacol. Sci., 22, 298-305.
-
(2001)
Trends Pharmacol. Sci.
, vol.22
, pp. 298-305
-
-
Pirmohamed, M.1
Park, B.K.2
-
10
-
-
48249093095
-
Integration and use of biomarkers in drug development, regulation and clinical practice: a US regulatory perspective
-
Amur, S., Frueh, F.W., Lesko, L.J. and Huang, S.M. (2008) Integration and use of biomarkers in drug development, regulation and clinical practice: a US regulatory perspective. Biomark. Med., 2, 305-311.
-
(2008)
Biomark. Med.
, vol.2
, pp. 305-311
-
-
Amur, S.1
Frueh, F.W.2
Lesko, L.J.3
Huang, S.M.4
-
11
-
-
0032793249
-
Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment
-
Ingelman-Sundberg, M., Oscarson, M. and McLellan, R.A. (1999) Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment. Trends Pharmacol. Sci., 20, 342-349.
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 342-349
-
-
Ingelman-Sundberg, M.1
Oscarson, M.2
McLellan, R.A.3
-
12
-
-
22944482153
-
Impact of the CYP2D6 ultra-rapid metabolizer genotype on doxepin pharmacokinetics and serotonin in platelets
-
Kirchheiner, J., Henckel, H.B., Franke, L., Meineke, I., Tzvetkov, M., Uebelhack, R., Roots, I. and Brockmoller, J. (2005) Impact of the CYP2D6 ultra-rapid metabolizer genotype on doxepin pharmacokinetics and serotonin in platelets. Pharmacogenet. Genomics, 15, 579-587.
-
(2005)
Pharmacogenet. Genomics
, vol.15
, pp. 579-587
-
-
Kirchheiner, J.1
Henckel, H.B.2
Franke, L.3
Meineke, I.4
Tzvetkov, M.5
Uebelhack, R.6
Roots, I.7
Brockmoller, J.8
-
13
-
-
3142519666
-
Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response
-
Kirchheiner, J., Nickchen, K., Bauer, M., Wong, M.L., Licinio, J., Roots, I. and Brockmoller, J. (2004) Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response. Mol. Psychiatry, 9, 442-473.
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 442-473
-
-
Kirchheiner, J.1
Nickchen, K.2
Bauer, M.3
Wong, M.L.4
Licinio, J.5
Roots, I.6
Brockmoller, J.7
-
14
-
-
84855968708
-
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype
-
Crews, K.R., Gaedigk, A., Dunnenberger, H.M., Klein, T.E., Shen, D.D., Callaghan, J.T., Kharasch, E.D. and Skaar, T.C. (2012) Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. Clin. Pharmacol. Ther., 91, 321-326.
-
(2012)
Clin. Pharmacol. Ther.
, vol.91
, pp. 321-326
-
-
Crews, K.R.1
Gaedigk, A.2
Dunnenberger, H.M.3
Klein, T.E.4
Shen, D.D.5
Callaghan, J.T.6
Kharasch, E.D.7
Skaar, T.C.8
-
15
-
-
78049326068
-
Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis
-
Mega, J.L., Simon, T., Collet, J.P., Anderson, J.L., Antman, E.M., Bliden, K., Cannon, C.P., Danchin, N., Giusti, B., Gurbel, P. et al. (2010) Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. JAMA, 304, 1821-1830.
-
(2010)
JAMA
, vol.304
, pp. 1821-1830
-
-
Mega, J.L.1
Simon, T.2
Collet, J.P.3
Anderson, J.L.4
Antman, E.M.5
Bliden, K.6
Cannon, C.P.7
Danchin, N.8
Giusti, B.9
Gurbel, P.10
-
16
-
-
32944454759
-
Pharmacogenomics and individualized drug therapy
-
Eichelbaum, M., Ingelman-Sundberg, M. and Evans, W.E. (2006) Pharmacogenomics and individualized drug therapy. Annu. Rev. Med., 57, 119-137.
-
(2006)
Annu. Rev. Med.
, vol.57
, pp. 119-137
-
-
Eichelbaum, M.1
Ingelman-Sundberg, M.2
Evans, W.E.3
-
17
-
-
3242762099
-
Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants
-
Schaeffeler, E., Fischer, C., Brockmeier, D., Wernet, D., Moerike, K., Eichelbaum, M., Zanger, U.M. and Schwab, M. (2004) Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants. Pharmacogenetics, 14, 407-417.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 407-417
-
-
Schaeffeler, E.1
Fischer, C.2
Brockmeier, D.3
Wernet, D.4
Moerike, K.5
Eichelbaum, M.6
Zanger, U.M.7
Schwab, M.8
-
18
-
-
0034671387
-
Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis
-
Ando, Y., Saka, H., Ando, M., Sawa, T., Muro, K., Ueoka, H., Yokoyama, A., Saitoh, S., Shimokata, K. and Hasegawa, Y. (2000) Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res., 60, 6921-6926.
-
(2000)
Cancer Res
, vol.60
, pp. 6921-6926
-
-
Ando, Y.1
Saka, H.2
Ando, M.3
Sawa, T.4
Muro, K.5
Ueoka, H.6
Yokoyama, A.7
Saitoh, S.8
Shimokata, K.9
Hasegawa, Y.10
-
19
-
-
24944503322
-
A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity
-
Yuan, H.Y., Chen, J.J., Lee, M.T., Wung, J.C., Chen, Y.F., Charng, M.J., Lu, M.J., Hung, C.R., Wei, C.Y., Chen, C.H. et al. (2005) A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity. Hum. Mol. Genet., 14, 1745-1751.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 1745-1751
-
-
Yuan, H.Y.1
Chen, J.J.2
Lee, M.T.3
Wung, J.C.4
Chen, Y.F.5
Charng, M.J.6
Lu, M.J.7
Hung, C.R.8
Wei, C.Y.9
Chen, C.H.10
-
20
-
-
0003005833
-
Bleeding complications to long-term oral anticoagulant therapy
-
Gullov, A.L., Koefoed, B.G. and Petersen, P. (1994) Bleeding complications to long-term oral anticoagulant therapy. J. Thromb. Thrombolysis, 1, 17-25.
-
(1994)
J. Thromb. Thrombolysis
, vol.1
, pp. 17-25
-
-
Gullov, A.L.1
Koefoed, B.G.2
Petersen, P.3
-
21
-
-
51649110496
-
A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose
-
Cooper, G.M., Johnson, J.A., Langaee, T.Y., Feng, H., Stanaway, I.B., Schwarz, U.I., Ritchie, M.D., Stein, C.M., Roden, D.M., Smith, J.D. et al. (2008) A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Blood, 112, 1022-1027.
-
(2008)
Blood
, vol.112
, pp. 1022-1027
-
-
Cooper, G.M.1
Johnson, J.A.2
Langaee, T.Y.3
Feng, H.4
Stanaway, I.B.5
Schwarz, U.I.6
Ritchie, M.D.7
Stein, C.M.8
Roden, D.M.9
Smith, J.D.10
-
22
-
-
0034872136
-
Pharmacogenetics of warfarin elimination and its clinical implications
-
Takahashi, H. and Echizen, H. (2001) Pharmacogenetics of warfarin elimination and its clinical implications. Clin. Pharmacokinet., 40, 587- 603.
-
(2001)
Clin. Pharmacokinet.
, vol.40
, pp. 587-603
-
-
Takahashi, H.1
Echizen, H.2
-
23
-
-
0015494743
-
Warfarin and the inhibition of vitamin K activity by an oxide metabolite
-
Bell, R.G. and Matschiner, J.T. (1972) Warfarin and the inhibition of vitamin K activity by an oxide metabolite. Nature, 237, 32-33.
-
(1972)
Nature
, vol.237
, pp. 32-33
-
-
Bell, R.G.1
Matschiner, J.T.2
-
24
-
-
63449117825
-
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose
-
Takeuchi, F., McGinnis, R., Bourgeois, S., Barnes, C., Eriksson, N., Soranzo, N., Whittaker, P., Ranganath, V., Kumanduri, V., McLaren, W. et al. (2009) A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet., 5, e1000433.
-
(2009)
PLoS Genet
, vol.5
-
-
Takeuchi, F.1
McGinnis, R.2
Bourgeois, S.3
Barnes, C.4
Eriksson, N.5
Soranzo, N.6
Whittaker, P.7
Ranganath, V.8
Kumanduri, V.9
McLaren, W.10
-
25
-
-
60849097257
-
Estimation of the warfarin dose with clinical and pharmacogenetic data
-
Klein, T.E., Altman, R.B., Eriksson, N., Gage, B.F., Kimmel, S.E., Lee, M.T., Limdi, N.A., Page, D., Roden, D.M., Wagner, M.J. et al. (2009) Estimation of the warfarin dose with clinical and pharmacogenetic data. N. Engl. J. Med., 360, 753-764.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 753-764
-
-
Klein, T.E.1
Altman, R.B.2
Eriksson, N.3
Gage, B.F.4
Kimmel, S.E.5
Lee, M.T.6
Limdi, N.A.7
Page, D.8
Roden, D.M.9
Wagner, M.J.10
-
26
-
-
77952570889
-
Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups
-
Limdi, N.A., Wadelius, M., Cavallari, L., Eriksson, N., Crawford, D.C., Lee, M.T., Chen, C.H., Motsinger-Reif, A., Sagreiya, H., Liu, N. et al. (2010) Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups. Blood, 115, 3827-3834.
-
(2010)
Blood
, vol.115
, pp. 3827-3834
-
-
Limdi, N.A.1
Wadelius, M.2
Cavallari, L.3
Eriksson, N.4
Crawford, D.C.5
Lee, M.T.6
Chen, C.H.7
Motsinger-Reif, A.8
Sagreiya, H.9
Liu, N.10
-
27
-
-
0029133354
-
Diagnostic analysis, clinical importance and molecular basis of dihydropyrimidine dehydrogenase deficiency
-
Gonzalez, F.J. and Fernandez-Salguero, P. (1995) Diagnostic analysis, clinical importance and molecular basis of dihydropyrimidine dehydrogenase deficiency. Trends Pharmacol. Sci., 16, 325-327.
-
(1995)
Trends Pharmacol. Sci.
, vol.16
, pp. 325-327
-
-
Gonzalez, F.J.1
Fernandez-Salguero, P.2
-
28
-
-
33645013092
-
Screening for dihydropyrimidine dehydrogenase deficiency: to do or not to do, that's the question
-
van Kuilenburg, A.B. (2006) Screening for dihydropyrimidine dehydrogenase deficiency: to do or not to do, that's the question. Cancer Invest., 24, 215-217.
-
(2006)
Cancer Invest
, vol.24
, pp. 215-217
-
-
van Kuilenburg, A.B.1
-
29
-
-
77649216536
-
Membrane transporters in drug development
-
Giacomini, K.M., Huang, S.M., Tweedie, D.J., Benet, L.Z., Brouwer, K.L., Chu, X., Dahlin, A., Evers, R., Fischer, V., Hillgren, K.M. et al. (2010) Membrane transporters in drug development. Nat. Rev. Drug Discov., 9, 215-236.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 215-236
-
-
Giacomini, K.M.1
Huang, S.M.2
Tweedie, D.J.3
Benet, L.Z.4
Brouwer, K.L.5
Chu, X.6
Dahlin, A.7
Evers, R.8
Fischer, V.9
Hillgren, K.M.10
-
30
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer, S., Burk, O., von Richter, O., Arnold, H.P., Brockmoller, J., Johne, A., Cascorbi, I., Gerloff, T., Roots, I., Eichelbaum, M. et al. (2000) Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl Acad. Sci. USA, 97, 3473-3478.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
Cascorbi, I.7
Gerloff, T.8
Roots, I.9
Eichelbaum, M.10
-
31
-
-
21444449731
-
ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation
-
Hauser, I.A., Schaeffeler, E., Gauer, S., Scheuermann, E.H., Wegner, B., Gossmann, J., Ackermann, H., Seidl, C., Hocher, B., Zanger, U.M. et al. (2005) ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation. J. Am. Soc. Nephrol., 16, 1501-1511.
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 1501-1511
-
-
Hauser, I.A.1
Schaeffeler, E.2
Gauer, S.3
Scheuermann, E.H.4
Wegner, B.5
Gossmann, J.6
Ackermann, H.7
Seidl, C.8
Hocher, B.9
Zanger, U.M.10
-
32
-
-
33845657889
-
Pharmacogenetics of ABCG2 and adverse reactions to gefitinib
-
Cusatis, G., Gregorc, V., Li, J., Spreafico, A., Ingersoll, R.G., Verweij, J., Ludovini, V., Villa, E., Hidalgo, M., Sparreboom, A. et al. (2006) Pharmacogenetics of ABCG2 and adverse reactions to gefitinib. J. Natl Cancer Inst., 98, 1739-1742.
-
(2006)
J. Natl Cancer Inst.
, vol.98
, pp. 1739-1742
-
-
Cusatis, G.1
Gregorc, V.2
Li, J.3
Spreafico, A.4
Ingersoll, R.G.5
Verweij, J.6
Ludovini, V.7
Villa, E.8
Hidalgo, M.9
Sparreboom, A.10
-
33
-
-
3042848580
-
Achieving greater reductions in cardiovascular risk: lessons from statin therapy on risk measures and risk reduction
-
Ballantyne, C.M. (2004) Achieving greater reductions in cardiovascular risk: lessons from statin therapy on risk measures and risk reduction. Am. Heart J., 148, S3-S8.
-
(2004)
Am. Heart J.
, vol.148
-
-
Ballantyne, C.M.1
-
34
-
-
49949104757
-
SLCO1B1 variants and statin-induced myopathy-a genomewide study
-
Link, E., Parish, S., Armitage, J., Bowman, L., Heath, S., Matsuda, F., Gut, I., Lathrop, M. and Collins, R. (2008) SLCO1B1 variants and statin-induced myopathy-a genomewide study. N. Engl. J. Med., 359, 789-799.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 789-799
-
-
Link, E.1
Parish, S.2
Armitage, J.3
Bowman, L.4
Heath, S.5
Matsuda, F.6
Gut, I.7
Lathrop, M.8
Collins, R.9
-
35
-
-
33645110538
-
Pharmacogenomics of human OATP transporters
-
Konig, J., Seithel, A., Gradhand, U. and Fromm, M.F. (2006) Pharmacogenomics of human OATP transporters. Naunyn. Schmiedebergs Arch. Pharmacol., 372, 432-443.
-
(2006)
Naunyn. Schmiedebergs Arch. Pharmacol.
, vol.372
, pp. 432-443
-
-
Konig, J.1
Seithel, A.2
Gradhand, U.3
Fromm, M.F.4
-
36
-
-
70349739250
-
The SLCO1B1*5 variant is associated with statin-induced side effects
-
Voora, D., Shah, S.H., Spasojevic, I., Ali, S., Reed, C.R., Salisbury, B.A. and Ginsburg, G.S. (2009) The SLCO1B1*5 variant is associated with statin-induced side effects. J. Am. Coll. Cardiol., 54, 1609-1616.
-
(2009)
J. Am. Coll. Cardiol.
, vol.54
, pp. 1609-1616
-
-
Voora, D.1
Shah, S.H.2
Spasojevic, I.3
Ali, S.4
Reed, C.R.5
Salisbury, B.A.6
Ginsburg, G.S.7
-
37
-
-
77954310138
-
Genetic involvement in statins induced myopathy
-
Puccetti, L., Ciani, F. and Auteri, A. (2010) Genetic involvement in statins induced myopathy. Preliminary data from an observational case-control study. Atherosclerosis, 211, 28-29.
-
(2010)
Atherosclerosis
, vol.211
, pp. 28-29
-
-
Puccetti, L.1
Ciani, F.2
Auteri, A.3
-
38
-
-
84862600938
-
The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy
-
Wilke, R.A., Ramsey, L.B., Johnson, S.G., Maxwell, W.D., McLeod, H.L., Voora, D., Krauss, R.M., Roden, D.M., Feng, Q., Cooper-Dehoff, R.M. et al. (2012) The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy. Clin. Pharmacol. Ther., 92, 112-117.
-
(2012)
Clin. Pharmacol. Ther.
, vol.92
, pp. 112-117
-
-
Wilke, R.A.1
Ramsey, L.B.2
Johnson, S.G.3
Maxwell, W.D.4
McLeod, H.L.5
Voora, D.6
Krauss, R.M.7
Roden, D.M.8
Feng, Q.9
Cooper-Dehoff, R.M.10
-
39
-
-
33645082244
-
Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions
-
Hung, S.I., Chung, W.H., Jee, S.H., Chen, W.C., Chang, Y.T., Lee, W.R., Hu, S.L., Wu, M.T., Chen, G.S., Wong, T.W. et al. (2006) Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. Pharmacogenet. Genomics, 16, 297-306.
-
(2006)
Pharmacogenet. Genomics
, vol.16
, pp. 297-306
-
-
Hung, S.I.1
Chung, W.H.2
Jee, S.H.3
Chen, W.C.4
Chang, Y.T.5
Lee, W.R.6
Hu, S.L.7
Wu, M.T.8
Chen, G.S.9
Wong, T.W.10
-
40
-
-
17144408997
-
The human leucocyte antigen-DRB1*1302-DQB1*0609-DPB1*0201 haplotype may be a strong genetic marker for aspirin-induced urticaria
-
Kim, S.H., Choi, J.H., Lee, K.W., Shin, E.S., Oh, H.B., Suh, C.H., Nahm, D.H. and Park, H.S. (2005) The human leucocyte antigen-DRB1*1302-DQB1*0609-DPB1*0201 haplotype may be a strong genetic marker for aspirin-induced urticaria. Clin. Exp. Allergy, 35, 339- 344.
-
(2005)
Clin. Exp. Allergy
, vol.35
, pp. 339-344
-
-
Kim, S.H.1
Choi, J.H.2
Lee, K.W.3
Shin, E.S.4
Oh, H.B.5
Suh, C.H.6
Nahm, D.H.7
Park, H.S.8
-
41
-
-
33748465178
-
Genetic mechanism of aspirin-induced urticaria/angioedema
-
Kim, S.H., Ye, Y.M., Lee, S.K. and Park, H.S. (2006) Genetic mechanism of aspirin-induced urticaria/angioedema. Curr. Opin. Allergy Clin. Immunol., 6, 266-270.
-
(2006)
Curr. Opin. Allergy Clin. Immunol.
, vol.6
, pp. 266-270
-
-
Kim, S.H.1
Ye, Y.M.2
Lee, S.K.3
Park, H.S.4
-
42
-
-
79551600984
-
Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population
-
Ozeki, T., Mushiroda, T., Yowang, A., Takahashi, A., Kubo, M., Shirakata, Y., Ikezawa, Z., Iijima, M., Shiohara, T., Hashimoto, K. et al. (2010) Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population. Hum. Mol. Genet., 20, 1034-1041.
-
(2010)
Hum. Mol. Genet.
, vol.20
, pp. 1034-1041
-
-
Ozeki, T.1
Mushiroda, T.2
Yowang, A.3
Takahashi, A.4
Kubo, M.5
Shirakata, Y.6
Ikezawa, Z.7
Iijima, M.8
Shiohara, T.9
Hashimoto, K.10
-
43
-
-
79953197983
-
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans
-
McCormack, M., Alfirevic, A., Bourgeois, S., Farrell, J.J., Kasperaviciute, D., Carrington, M., Sills, G.J., Marson, T., Jia, X., de Bakker, P.I. et al. (2011) HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. N. Engl. J. Med., 364, 1134-1143.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 1134-1143
-
-
McCormack, M.1
Alfirevic, A.2
Bourgeois, S.3
Farrell, J.J.4
Kasperaviciute, D.5
Carrington, M.6
Sills, G.J.7
Marson, T.8
Jia, X.9
de Bakker, P.I.10
-
44
-
-
12144291646
-
Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some
-
Hughes, A.R., Mosteller, M., Bansal, A.T., Davies, K., Haneline, S.A., Lai, E.H., Nangle, K., Scott, T., Spreen, W.R., Warren, L.L. et al. (2004) Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations. Pharmacogenomics, 5, 203- 211.
-
(2004)
Pharmacogenomics
, vol.5
, pp. 203-211
-
-
Hughes, A.R.1
Mosteller, M.2
Bansal, A.T.3
Davies, K.4
Haneline, S.A.5
Lai, E.H.6
Nangle, K.7
Scott, T.8
Spreen, W.R.9
Warren, L.L.10
-
45
-
-
33646181088
-
How TCRs bind MHCs, peptides, and coreceptors
-
Rudolph, M.G., Stanfield, R.L. and Wilson, I.A. (2006) How TCRs bind MHCs, peptides, and coreceptors. Annu. Rev. Immunol., 24, 419-466.
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 419-466
-
-
Rudolph, M.G.1
Stanfield, R.L.2
Wilson, I.A.3
-
46
-
-
7944234979
-
Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells
-
Nassif, A., Bensussan, A., Boumsell, L., Deniaud, A., Moslehi, H., Wolkenstein, P., Bagot, M. and Roujeau, J.C. (2004) Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells. J. Allergy Clin. Immunol., 114, 1209-1215.
-
(2004)
J. Allergy Clin. Immunol.
, vol.114
, pp. 1209-1215
-
-
Nassif, A.1
Bensussan, A.2
Boumsell, L.3
Deniaud, A.4
Moslehi, H.5
Wolkenstein, P.6
Bagot, M.7
Roujeau, J.C.8
-
47
-
-
0142087834
-
Delayed drug hypersensitivity reactions
-
Pichler, W.J. (2003) Delayed drug hypersensitivity reactions. Ann. Intern. Med., 139, 683-693.
-
(2003)
Ann. Intern. Med.
, vol.139
, pp. 683-693
-
-
Pichler, W.J.1
-
48
-
-
0030918532
-
Penicilloyl peptides are recognized as T cell antigenic determinants in penicillin allergy
-
Padovan, E., Bauer, T., Tongio, M.M., Kalbacher, H. and Weltzien, H.U. (1997) Penicilloyl peptides are recognized as T cell antigenic determinants in penicillin allergy. Eur. J. Immunol., 27, 1303-1307.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 1303-1307
-
-
Padovan, E.1
Bauer, T.2
Tongio, M.M.3
Kalbacher, H.4
Weltzien, H.U.5
-
49
-
-
33645766933
-
Pharmacological interaction of drugs with immune receptors: the p-i concept
-
Pichler, W.J., Beeler, A., Keller, M., Lerch, M., Posadas, S., Schmid, D., Spanou, Z., Zawodniak, A. and Gerber, B. (2006) Pharmacological interaction of drugs with immune receptors: the p-i concept. Allergol. Int., 55, 17-25.
-
(2006)
Allergol. Int.
, vol.55
, pp. 17-25
-
-
Pichler, W.J.1
Beeler, A.2
Keller, M.3
Lerch, M.4
Posadas, S.5
Schmid, D.6
Spanou, Z.7
Zawodniak, A.8
Gerber, B.9
-
50
-
-
84862776700
-
Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome
-
Wei, C.Y., Chung, W.H., Huang, H.W., Chen, Y.T. and Hung, S.I. (2012) Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome. J. Allergy Clin. Immunol, 129, 1562-1569.
-
(2012)
J. Allergy Clin. Immunol
, vol.129
, pp. 1562-1569
-
-
Wei, C.Y.1
Chung, W.H.2
Huang, H.W.3
Chen, Y.T.4
Hung, S.I.5
-
51
-
-
34948839971
-
HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome
-
Ou Yang, C.W., Hung, S.I., Juo, C.G., Lin, Y.P., Fang, W.H., Lu, I.H., Chen, S.T. and Chen, Y.T. (2007) HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome. J. Allergy Clin. Immunol., 120, 870-877.
-
(2007)
J. Allergy Clin. Immunol.
, vol.120
, pp. 870-877
-
-
Ou Yang, C.W.1
Hung, S.I.2
Juo, C.G.3
Lin, Y.P.4
Fang, W.H.5
Lu, I.H.6
Chen, S.T.7
Chen, Y.T.8
-
52
-
-
2942627194
-
Pharmacogenetic study of statin therapy and cholesterol reduction
-
Chasman, D.I., Posada, D., Subrahmanyan, L., Cook, N.R., Stanton, V.P. Jr and Ridker, P.M. * Pharmacogenetic study of statin therapy and cholesterol reduction. JAMA, 291, 2821-2827.
-
(2004)
JAMA
, vol.291
, pp. 2821-2827
-
-
Chasman, D.I.1
Posada, D.2
Subrahmanyan, L.3
Cook, N.R.4
Stanton Jr., V.P.5
Ridker, P.M.6
-
53
-
-
55449097874
-
Pharmacogenetics of apolipoprotein E gene during lipid-lowering therapy: lipid levels and prevention of coronary heart disease
-
Nieminen, T., Kahonen, M., Viiri, L.E., Gronroos, P. and Lehtimaki, T. (2008) Pharmacogenetics of apolipoprotein E gene during lipid-lowering therapy: lipid levels and prevention of coronary heart disease. Pharmacogenomics, 9, 1475-1486.
-
(2008)
Pharmacogenomics
, vol.9
, pp. 1475-1486
-
-
Nieminen, T.1
Kahonen, M.2
Viiri, L.E.3
Gronroos, P.4
Lehtimaki, T.5
-
54
-
-
67849094103
-
APOE gene polymorphisms and response to statin therapy
-
Zintzaras, E., Kitsios, G.D., Triposkiadis, F., Lau, J. and Raman, G. (2009) APOE gene polymorphisms and response to statin therapy. Pharmacogenomics J., 9, 248-257.
-
(2009)
Pharmacogenomics J
, vol.9
, pp. 248-257
-
-
Zintzaras, E.1
Kitsios, G.D.2
Triposkiadis, F.3
Lau, J.4
Raman, G.5
-
55
-
-
67651196989
-
Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response
-
Voora, D., Shah, S.H., Reed, C.R., Zhai, J., Crosslin, D.R., Messer, C., Salisbury, B.A. and Ginsburg, G.S. (2008) Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response. Circ. Cardiovasc. Genet., 1, 100-106.
-
(2008)
Circ. Cardiovasc. Genet.
, vol.1
, pp. 100-106
-
-
Voora, D.1
Shah, S.H.2
Reed, C.R.3
Zhai, J.4
Crosslin, D.R.5
Messer, C.6
Salisbury, B.A.7
Ginsburg, G.S.8
-
56
-
-
84863229143
-
Statins personalized
-
Superko, H.R., Momary, K.M. and Li, Y. (2012) Statins personalized. Med. Clin. North Am., 96, 123-139.
-
(2012)
Med. Clin. North Am.
, vol.96
, pp. 123-139
-
-
Superko, H.R.1
Momary, K.M.2
Li, Y.3
-
57
-
-
0037006623
-
Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
-
Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A.M., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D. et al. (2002) Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet, 359, 727-732.
-
(2002)
Lancet
, vol.359
, pp. 727-732
-
-
Mallal, S.1
Nolan, D.2
Witt, C.3
Masel, G.4
Martin, A.M.5
Moore, C.6
Sayer, D.7
Castley, A.8
Mamotte, C.9
Maxwell, D.10
-
58
-
-
15244349566
-
HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol
-
Hung, S.I., Chung, W.H., Liou, L.B., Chu, C.C., Lin, M., Huang, H.P., Lin, Y.L., Lan, J.L., Yang, L.C., Hong, H.S. et al. (2005) HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. Proc. Natl Acad. Sci. USA, 102, 4134-4139.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 4134-4139
-
-
Hung, S.I.1
Chung, W.H.2
Liou, L.B.3
Chu, C.C.4
Lin, M.5
Huang, H.P.6
Lin, Y.L.7
Lan, J.L.8
Yang, L.C.9
Hong, H.S.10
-
59
-
-
61549115662
-
HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis
-
Kaniwa, N., Saito, Y., Aihara, M., Matsunaga, K., Tohkin, M., Kurose, K., Sawada, J., Furuya, H., Takahashi, Y., Muramatsu, M. et al. (2008) HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis. Pharmacogenomics, 9, 1617-1622.
-
(2008)
Pharmacogenomics
, vol.9
, pp. 1617-1622
-
-
Kaniwa, N.1
Saito, Y.2
Aihara, M.3
Matsunaga, K.4
Tohkin, M.5
Kurose, K.6
Sawada, J.7
Furuya, H.8
Takahashi, Y.9
Muramatsu, M.10
-
60
-
-
38149108354
-
-
Lonjou, C., Borot, N., Sekula, P., Ledger, N., Thomas, L., Halevy, S., Naldi, L., Bouwes-Bavinck, J.N., Sidoroff, A., de Toma, C. et al. (2008) A European study of HLA-B in Stevens-Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs. Pharmacogenet. Genomics, 18, 99-107.
-
(2008)
Pharmacogenet. Genomics
, vol.18
, pp. 99-107
-
-
Lonjou, C.1
Borot, N.2
Sekula, P.3
Ledger, N.4
Thomas, L.5
Halevy, S.6
Naldi, L.7
Bouwes-Bavinck, J.N.8
Sidoroff, A.9
de Toma, C.10
-
61
-
-
0031861918
-
Delayed hypersensitivity to aminopenicillins is related to major histocompatibility complex genes
-
Romano, A., De Santis, A., Romito, A., Di Fonso, M., Venuti, A., Gasbarrini, G.B. and Manna, R. (1998) Delayed hypersensitivity to aminopenicillins is related to major histocompatibility complex genes. Ann. Allergy Asthma Immunol., 80, 433-437.
-
(1998)
Ann. Allergy Asthma Immunol.
, vol.80
, pp. 433-437
-
-
Romano, A.1
De Santis, A.2
Romito, A.3
Di Fonso, M.4
Venuti, A.5
Gasbarrini, G.B.6
Manna, R.7
-
62
-
-
79957523368
-
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles
-
Lucena, M.I., Molokhia, M., Shen, Y., Urban, T.J., Aithal, G.P., Andrade, R.J., Day, C.P., Ruiz-Cabello, F., Donaldson, P.T., Stephens, C. et al. (2011) Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology, 141, 338-347.
-
(2011)
Gastroenterology
, vol.141
, pp. 338-347
-
-
Lucena, M.I.1
Molokhia, M.2
Shen, Y.3
Urban, T.J.4
Aithal, G.P.5
Andrade, R.J.6
Day, C.P.7
Ruiz-Cabello, F.8
Donaldson, P.T.9
Stephens, C.10
-
63
-
-
1842784823
-
Medical genetics: a marker for Stevens-Johnson syndrome
-
Chung, W.H., Hung, S.I., Hong, H.S., Hsih, M.S., Yang, L.C., Ho, H.C., Wu, J.Y. and Chen, Y.T. (2004) Medical genetics: a marker for Stevens-Johnson syndrome. Nature, 428, 486.
-
(2004)
Nature
, vol.428
, pp. 486
-
-
Chung, W.H.1
Hung, S.I.2
Hong, H.S.3
Hsih, M.S.4
Yang, L.C.5
Ho, H.C.6
Wu, J.Y.7
Chen, Y.T.8
-
64
-
-
34748816239
-
Clozapine-induced agranulocytosis in schizophrenic Caucasians: confirming clues for associations with human leukocyte class I and II antigens
-
Dettling, M., Cascorbi, I., Opgen-Rhein, C. and Schaub, R. (2007) Clozapine-induced agranulocytosis in schizophrenic Caucasians: confirming clues for associations with human leukocyte class I and II antigens. Pharmacogenomics J., 7, 325-332.
-
(2007)
Pharmacogenomics J
, vol.7
, pp. 325-332
-
-
Dettling, M.1
Cascorbi, I.2
Opgen-Rhein, C.3
Schaub, R.4
-
65
-
-
67649859295
-
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
-
Daly, A.K., Donaldson, P.T., Bhatnagar, P., Shen, Y., Pe'er, I., Floratos, A., Daly, M.J., Goldstein, D.B., John, S., Nelson, M.R. et al. (2009) HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat. Genet., 41, 816-819.
-
(2009)
Nat. Genet.
, vol.41
, pp. 816-819
-
-
Daly, A.K.1
Donaldson, P.T.2
Bhatnagar, P.3
Shen, Y.4
Pe'er, I.5
Floratos, A.6
Daly, M.J.7
Goldstein, D.B.8
John, S.9
Nelson, M.R.10
-
66
-
-
77955082302
-
A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury
-
Singer, J.B., Lewitzky, S., Leroy, E., Yang, F., Zhao, X., Klickstein, L., Wright, T.M., Meyer, J. and Paulding, C.A. (2010) A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nat. Genet., 42, 711-714.
-
(2010)
Nat. Genet.
, vol.42
, pp. 711-714
-
-
Singer, J.B.1
Lewitzky, S.2
Leroy, E.3
Yang, F.4
Zhao, X.5
Klickstein, L.6
Wright, T.M.7
Meyer, J.8
Paulding, C.A.9
-
67
-
-
77952937737
-
HLA-B*5901 is strongly associated with methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis
-
Kim, S.H., Kim, M., Lee, K.W., Kang, H.R., Park, H.W. and Jee, Y.K. (2010) HLA-B*5901 is strongly associated with methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis. Pharmacogenomics, 11, 879-884.
-
(2010)
Pharmacogenomics
, vol.11
, pp. 879-884
-
-
Kim, S.H.1
Kim, M.2
Lee, K.W.3
Kang, H.R.4
Park, H.W.5
Jee, Y.K.6
-
68
-
-
33746767604
-
HLA-dependent hypersensitivity to nevirapine in Sardinian HIV patients
-
Littera, R., Carcassi, C., Masala, A., Piano, P., Serra, P., Ortu, F., Corso, N., Casula, B., La Nasa, G., Contu, L. et al. (2006) HLA-dependent hypersensitivity to nevirapine in Sardinian HIV patients. AIDS, 20, 1621- 1626.
-
(2006)
AIDS
, vol.20
, pp. 1621-1626
-
-
Littera, R.1
Carcassi, C.2
Masala, A.3
Piano, P.4
Serra, P.5
Ortu, F.6
Corso, N.7
Casula, B.8
La Nasa, G.9
Contu, L.10
-
69
-
-
33845945094
-
HLA-Cw8 primarily associated with hypersensitivity to nevirapine
-
Gatanaga, H., Yazaki, H., Tanuma, J., Honda, M., Genka, I., Teruya, K., Tachikawa, N., Kikuchi, Y. and Oka, S. (2007) HLA-Cw8 primarily associated with hypersensitivity to nevirapine. AIDS, 21, 264-265.
-
(2007)
AIDS
, vol.21
, pp. 264-265
-
-
Gatanaga, H.1
Yazaki, H.2
Tanuma, J.3
Honda, M.4
Genka, I.5
Teruya, K.6
Tachikawa, N.7
Kikuchi, Y.8
Oka, S.9
-
70
-
-
59549096348
-
HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients
-
Chantarangsu, S., Mushiroda, T., Mahasirimongkol, S., Kiertiburanakul, S., Sungkanuparph, S., Manosuthi, W., Tantisiriwat, W., Charoenyingwattana, A., Sura, T., Chantratita, W. et al. (2009) HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients. Pharmacogenet. Genomics, 19, 139-146.
-
(2009)
Pharmacogenet. Genomics
, vol.19
, pp. 139-146
-
-
Chantarangsu, S.1
Mushiroda, T.2
Mahasirimongkol, S.3
Kiertiburanakul, S.4
Sungkanuparph, S.5
Manosuthi, W.6
Tantisiriwat, W.7
Charoenyingwattana, A.8
Sura, T.9
Chantratita, W.10
-
71
-
-
12144260460
-
Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts
-
Martin, A.M., Nolan, D., James, I., Cameron, P., Keller, J., Moore, C., Phillips, E., Christiansen, F.T. and Mallal, S. (2005) Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts. AIDS, 19, 97-99.
-
(2005)
AIDS
, vol.19
, pp. 97-99
-
-
Martin, A.M.1
Nolan, D.2
James, I.3
Cameron, P.4
Keller, J.5
Moore, C.6
Phillips, E.7
Christiansen, F.T.8
Mallal, S.9
-
72
-
-
57449118501
-
Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B * 1502 allele in Thai population
-
Locharernkul, C., Loplumlert, J., Limotai, C., Korkij, W., Desudchit, T., Tongkobpetch, S., Kangwanshiratada, O., Hirankarn, N., Suphapeetiporn, K. and Shotelersuk, V. (2008) Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B * 1502 allele in Thai population. Epilepsia, 49, 2087-2091.
-
(2008)
Epilepsia
, vol.49
, pp. 2087-2091
-
-
Locharernkul, C.1
Loplumlert, J.2
Limotai, C.3
Korkij, W.4
Desudchit, T.5
Tongkobpetch, S.6
Kangwanshiratada, O.7
Hirankarn, N.8
Suphapeetiporn, K.9
Shotelersuk, V.10
-
73
-
-
44049102035
-
Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis
-
Kindmark, A., Jawaid, A., Harbron, C.G., Barratt, B.J., Bengtsson, O.F., Andersson, T.B., Carlsson, S., Cederbrant, K.E., Gibson, N.J., Armstrong, M. et al. (2008) Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis. Pharmacogenomics J., 8, 186-195.
-
(2008)
Pharmacogenomics J
, vol.8
, pp. 186-195
-
-
Kindmark, A.1
Jawaid, A.2
Harbron, C.G.3
Barratt, B.J.4
Bengtsson, O.F.5
Andersson, T.B.6
Carlsson, S.7
Cederbrant, K.E.8
Gibson, N.J.9
Armstrong, M.10
|