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Volumn 98, Issue 23, 2006, Pages 1739-1742

Pharmacogenetics of ABCG2 and adverse reactions to gefitinib

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CARRIER PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB;

EID: 33845657889     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djj469     Document Type: Article
Times cited : (224)

References (26)
  • 1
    • 0012381722 scopus 로고    scopus 로고
    • Multiinstitutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]
    • Fukuoka M, Yano S, Giaccone G, Tamura T, Nakagawa K, Douillard JY, et al. Multiinstitutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]. J Clin Oncol 2003;21:2237-46.
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3    Tamura, T.4    Nakagawa, K.5    Douillard, J.Y.6
  • 2
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
    • Kris MG, Natale RB, Herbst RS, Lynch TJ Jr, Prager D, Belani CP, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial. JAMA 2003;290:2149-58.
    • (2003) JAMA , vol.290 , pp. 2149-2158
    • Kris, M.G.1    Natale, R.B.2    Herbst, R.S.3    Lynch Jr., T.J.4    Prager, D.5    Belani, C.P.6
  • 3
    • 20044370274 scopus 로고    scopus 로고
    • Skin rash and good performance status predict improved survival with gefitinib in patients with advanced non-small cell lung cancer
    • Mohamed MK, Ramalingam S, Lin Y, Gooding W, Belani CP. Skin rash and good performance status predict improved survival with gefitinib in patients with advanced non-small cell lung cancer. Ann Oncol 2005;16:780-5.
    • (2005) Ann Oncol , vol.16 , pp. 780-785
    • Mohamed, M.K.1    Ramalingam, S.2    Lin, Y.3    Gooding, W.4    Belani, C.P.5
  • 4
    • 13844298864 scopus 로고    scopus 로고
    • Treatment of non-small cell lung cancer with gefitinib ('Iressa', ZD1839): The Greek experience with a compassionate-use program
    • Razis E, Skarlos D, Briasoulis E, Dimopoulos M, Fountzilas G, Lambropoulos S, et al. Treatment of non-small cell lung cancer with gefitinib ('Iressa', ZD1839): The Greek experience with a compassionate-use program. Anticancer Drugs 2005;16:191-8.
    • (2005) Anticancer Drugs , vol.16 , pp. 191-198
    • Razis, E.1    Skarlos, D.2    Briasoulis, E.3    Dimopoulos, M.4    Fountzilas, G.5    Lambropoulos, S.6
  • 5
    • 20844443812 scopus 로고    scopus 로고
    • Clinical benefit in NSCLC: Advanced-stage patients require symptom-improving palliation. Experiences from the 'Iressa' expanded access program
    • Schutte W, Nagel S, Schaedlich S, Brust D, Blankenburg T. Clinical benefit in NSCLC: Advanced-stage patients require symptom-improving palliation. Experiences from the 'Iressa' expanded access program. Onkologie 2005;28:195-8.
    • (2005) Onkologie , vol.28 , pp. 195-198
    • Schutte, W.1    Nagel, S.2    Schaedlich, S.3    Brust, D.4    Blankenburg, T.5
  • 7
    • 24644513947 scopus 로고    scopus 로고
    • Cutaneous adverse effects with HER1/EGFR-targeted agents: Is there a silver lining?
    • Perez-Soler R, Saltz L. Cutaneous adverse effects with HER1/ EGFR-targeted agents: Is there a silver lining? J Clin Oncol 2005; 23:5235-46.
    • (2005) J Clin Oncol , vol.23 , pp. 5235-5246
    • Perez-Soler, R.1    Saltz, L.2
  • 8
    • 18144370731 scopus 로고    scopus 로고
    • Mechanisms of resistance to anticancer drugs: The role of the polymorphic ABC transporters ABCB1 and ABCG2
    • Lepper ER, Nooter K, Verweij J, Acharya MR, Figg WD, Sparreboom A. Mechanisms of resistance to anticancer drugs: The role of the polymorphic ABC transporters ABCB1 and ABCG2. Pharmacogenomics 2005;6: 115-38.
    • (2005) Pharmacogenomics , vol.6 , pp. 115-138
    • Lepper, E.R.1    Nooter, K.2    Verweij, J.3    Acharya, M.R.4    Figg, W.D.5    Sparreboom, A.6
  • 9
    • 20144389530 scopus 로고    scopus 로고
    • Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib)
    • Elkind NB, Szentpetery Z, Apati A, Ozvegy-Laczka C, Varady G, Ujhelly O, et al. Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib). Cancer Res 2005;65:1770-7.
    • (2005) Cancer Res , vol.65 , pp. 1770-1777
    • Elkind, N.B.1    Szentpetery, Z.2    Apati, A.3    Ozvegy-Laczka, C.4    Varady, G.5    Ujhelly, O.6
  • 11
    • 13944269488 scopus 로고    scopus 로고
    • , ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance
    • , ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance. Cancer Res 2005;65:1541-6.
    • (2005) Cancer Res , vol.65 , pp. 1541-1546
    • Nakamura, Y.1    Oka, M.2    Soda, H.3    Shiozawa, K.4    Yoshikawa, M.5    Itoh, A.6
  • 12
    • 33845622043 scopus 로고    scopus 로고
    • Gefitinib and erlotinib, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors, are substrates for the breast cancer resistance protein (BCRP)/ABCG2 transporter
    • (Abstract A251)
    • Li J, Sparreboom A, Zhao M, Robey RW, Bates SE, Baker SD. Gefitinib and erlotinib, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors, are substrates for the breast cancer resistance protein (BCRP)/ABCG2 transporter. Clin Cancer Res 2005;115:120 (Abstract A251).
    • (2005) Clin Cancer Res , vol.115 , pp. 120
    • Li, J.1    Sparreboom, A.2    Zhao, M.3    Robey, R.W.4    Bates, S.E.5    Baker, S.D.6
  • 13
    • 2442638937 scopus 로고    scopus 로고
    • High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter
    • Ozvegy-Laczka C, Hegedus T, Varady G, Ujhelly O, Schuetz JD, Varadi A, et al. High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter. Mol Pharmacol 2004;65:1485-95.
    • (2004) Mol Pharmacol , vol.65 , pp. 1485-1495
    • Ozvegy-Laczka, C.1    Hegedus, T.2    Varady, G.3    Ujhelly, O.4    Schuetz, J.D.5    Varadi, A.6
  • 14
    • 33845396981 scopus 로고    scopus 로고
    • Pharmacogenomics of the human ATP-binding cassette transporter ABCG2
    • in press
    • Gardner ER, Figg WD, Sparreboom A. Pharmacogenomics of the human ATP-binding cassette transporter ABCG2. Curr Pharmacogenomics. 2006;4:iN press.
    • (2006) Curr Pharmacogenomics , pp. 4
    • Gardner, E.R.1    Figg, W.D.2    Sparreboom, A.3
  • 15
    • 0036598543 scopus 로고    scopus 로고
    • C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance
    • Imai Y, Nakane M, Kage K, Tsukahara S, Ishikawa E, Tsuruo T, et al. C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. Mol Cancer Ther 2002;1:611-6.
    • (2002) Mol Cancer Ther , vol.1 , pp. 611-616
    • Imai, Y.1    Nakane, M.2    Kage, K.3    Tsukahara, S.4    Ishikawa, E.5    Tsuruo, T.6
  • 16
    • 32944469959 scopus 로고    scopus 로고
    • G2677T and C3435T genotype and haplotype are associated with hepatic ABCB1 (MDR1) expression
    • Song P, Lamba JK, Zhang L, Schuetz E, Shukla N, Meibohm B, et al. G2677T and C3435T genotype and haplotype are associated with hepatic ABCB1 (MDR1) expression. J Clin Pharmacol 2006;46:373-9.
    • (2006) J Clin Pharmacol , vol.46 , pp. 373-379
    • Song, P.1    Lamba, J.K.2    Zhang, L.3    Schuetz, E.4    Shukla, N.5    Meibohm, B.6
  • 17
    • 25144433260 scopus 로고    scopus 로고
    • Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability
    • Wang D, Johnson AD, Papp AC, Kroetz DL, Sadee W. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenet Genomics 2005;15:693-704.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 693-704
    • Wang, D.1    Johnson, A.D.2    Papp, A.C.3    Kroetz, D.L.4    Sadee, W.5
  • 18
    • 27244444360 scopus 로고    scopus 로고
    • Selecting patients for epidermal growth factor receptor inhibitor treatment: A FISH story or a tale of mutations?
    • Johnson BE, Janne PA. Selecting patients for epidermal growth factor receptor inhibitor treatment: A FISH story or a tale of mutations? J Clin Oncol 2005;23:6813-6.
    • (2005) J Clin Oncol , vol.23 , pp. 6813-6816
    • Johnson, B.E.1    Janne, P.A.2
  • 19
    • 19844375720 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in non-small-cell lung cancer: Implications for treatment and tumor biology
    • Janne PA, Engelman JA, Johnson BE. Epidermal growth factor receptor mutations in non-small-cell lung cancer: Implications for treatment and tumor biology. J Clin Oncol 2005;23:3227-34.
    • (2005) J Clin Oncol , vol.23 , pp. 3227-3234
    • Janne, P.A.1    Engelman, J.A.2    Johnson, B.E.3
  • 20
    • 0034652578 scopus 로고    scopus 로고
    • Length and loss of heterozygosity of an intron 1 polymorphic sequence of egfr is related to cytogenetic alterations and epithelial growth factor receptor expression
    • Buerger H, Gebhardt F, Schmidt H, Beckmann A, Hutmacher K, Simon R, et al. Length and loss of heterozygosity of an intron 1 polymorphic sequence of egfr is related to cytogenetic alterations and epithelial growth factor receptor expression. Cancer Res 2000;60:854-7.
    • (2000) Cancer Res , vol.60 , pp. 854-857
    • Buerger, H.1    Gebhardt, F.2    Schmidt, H.3    Beckmann, A.4    Hutmacher, K.5    Simon, R.6
  • 21
    • 0040886242 scopus 로고    scopus 로고
    • Modulation of epidermal growth factor receptor gene transcription by a polymorphic dinucleotide repeat in intron 1
    • Gebhardt F, Zanker KS, Brandt B. Modulation of epidermal growth factor receptor gene transcription by a polymorphic dinucleotide repeat in intron 1. J Biol Chem 1999;274:13176-80.
    • (1999) J Biol Chem , vol.274 , pp. 13176-13180
    • Gebhardt, F.1    Zanker, K.S.2    Brandt, B.3
  • 22
    • 11244319884 scopus 로고    scopus 로고
    • A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter
    • Liu W, Innocenti F, Wu NM, Desai AA, Dolan ME, Cook EH Jr, et al. A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter. Cancer Res 2005; 65:46-53.
    • (2005) Cancer Res , vol.65 , pp. 46-53
    • Liu, W.1    Innocenti, F.2    Wu, N.M.3    Desai, A.A.4    Dolan, M.E.5    Cook Jr., E.H.6
  • 23
    • 10844264628 scopus 로고    scopus 로고
    • An epidermal growth factor receptor intron 1 polymorphism mediates response to epidermal growth factor receptor inhibitors
    • Amador ML, Oppenheimer D, Perea S, Maitra A, Cusati G, Iacobuzio-Donahue C, et al. An epidermal growth factor receptor intron 1 polymorphism mediates response to epidermal growth factor receptor inhibitors. Cancer Res 2004;64:9139-43.
    • (2004) Cancer Res , vol.64 , pp. 9139-9143
    • Amador, M.L.1    Oppenheimer, D.2    Perea, S.3    Maitra, A.4    Cusati, G.5    Iacobuzio-Donahue, C.6
  • 24
    • 4644285519 scopus 로고    scopus 로고
    • Effects of gefitinib on serum epidermal growth factor receptor and HER2 in patients with advanced non-small cell lung cancer
    • Gregorc V, Ceresoli GL, Floriani I, Spreafico A, Bencardino KB, Ludovini V, et al. Effects of gefitinib on serum epidermal growth factor receptor and HER2 in patients with advanced non-small cell lung cancer. Clin Cancer Res 2004;10(Pt 1):6006-12.
    • (2004) Clin Cancer Res , vol.10 , Issue.PART 1 , pp. 6006-6012
    • Gregorc, V.1    Ceresoli, G.L.2    Floriani, I.3    Spreafico, A.4    Bencardino, K.B.5    Ludovini, V.6
  • 25
    • 7244232706 scopus 로고    scopus 로고
    • Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump
    • Burger H, van Tol H, Boersma AW, Brok M, Wiemer EA, Stoter G, et al. Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump. Blood 2004;104: 2940-2.
    • (2004) Blood , vol.104 , pp. 2940-2942
    • Burger, H.1    van Tol, H.2    Boersma, A.W.3    Brok, M.4    Wiemer, E.A.5    Stoter, G.6
  • 26
    • 0003832405 scopus 로고    scopus 로고
    • NCSS and PASS. Kaysville (UT); Available at: [Last accessed: October 27 2006.]
    • Hintze J. NCSS and PASS. Number Cruncher Statistical Systems. Kaysville (UT); 2004. Available at: http://www.ncss.com. [Last accessed: October 27, 2006.]
    • (2004) Number Cruncher Statistical Systems
    • Hintze, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.