Selected C7-substituted chromone derivatives as monoamine oxidase inhibitors

Bioorganic Chemistry

Volumn 45, Issue , 2012, Pages 1-11

  Legoabe, Lesetja J ^a   Petzer, Anél ^a   Petzer, Jacobus P ^a  

^a NORTH WEST UNIVERSITY   (South Africa)

Author keywords

Chromone; Coumarin; Inhibition; Monoamine oxidase; Reversible; Structure activity relationship

Indexed keywords

3 [[(4 OXO 4H CHROMEN 7 YL)OXY]METHYL]BENZONITRILE; 4 [[(4 OXO 4H CHROMEN 7 YL)OXY]METHYL]BENZONITRILE; 7 (2 PHENYLETHOXY) 4H CHROMEN 4 ONE; 7 (3 PHENYLPROPOXY) 4H CHROMEN 4 ONE; 7 (BENZYLOXY) 4H CHROMEN 4 ONE; 7 [(3 BROMOBENZYL)OXY] 4H CHROMEN 4 ONE; 7 [(3 CHLOROBENZYL)OXY] 4H CHROMEN 4 ONE; 7 [(3 FLUOROBENZYL)OXY] 4H CHROMEN 4 ONE; 7 [(3 METHYLBENZYL)OXY] 4H CHROMEN 4 ONE; 7 [(4 BROMOBENZYL)OXY] 4H CHROMEN 4 ONE; 7 [(4 CHLOROBENZYL)OXY] 4H CHROMEN 4 ONE; 7 [(4 FLUOROBENZYL)OXY] 4H CHROMEN 4 ONE; 7 [(4 METHYLBENZYL)OXY] 4H CHROMEN 4 ONE; 7 [2 (4 BROMOPHENYL)ETHOXY] 4H CHROMEN 4 ONE; 7 [[4 (TRIFLUOROMETHYL)BENZYL]OXY] 4H CHROMEN 4 ONE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; CHROMONE DERIVATIVE; MONOAMINE OXIDASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CATALYTIC DOMAIN; CHROMONES; COUMARINS; HUMANS; KINETICS; MOLECULAR DOCKING SIMULATION; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; PROTEIN BINDING; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84867122490     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2012.08.003     Document Type: Article

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