-
1
-
-
56749176442
-
LKB1; linking cell structure and tumor suppression
-
Hezel, A.F. and Bardeesy, N. (2008) LKB1; linking cell structure and tumor suppression. Oncogene, 27, 6908-6919.
-
(2008)
Oncogene
, vol.27
, pp. 6908-6919
-
-
Hezel, A.F.1
Bardeesy, N.2
-
2
-
-
0000152018
-
Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits; a syndrome of diagnostic significance
-
Jeghers, H., Mc, K.V. and Katz, K.H. (1949) Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits; a syndrome of diagnostic significance. N. Engl. J. Med., 241, 1031-1036.
-
(1949)
N. Engl. J. Med.
, vol.241
, pp. 1031-1036
-
-
Jeghers, H.1
Mc, K.V.2
Katz, K.H.3
-
3
-
-
0032495530
-
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
-
Hemminki, A., Markie, D., Tomlinson, I., Avizienyte, E., Roth, S., Loukola, A., Bignell, G., Warren, W., Aminoff, M., Hoglund, P. et al. [1998(] A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature, 391, 184-187.
-
(1998)
Nature
, vol.391
, pp. 184-187
-
-
Hemminki, A.1
Markie, D.2
Tomlinson, I.3
Avizienyte, E.4
Roth, S.5
Loukola, A.6
Bignell, G.7
Warren, W.8
Aminoff, M.9
Hoglund, P.10
-
4
-
-
0031974516
-
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
-
Jenne, D.E., Reimann, H., Nezu, J., Friedel, W., Loff, S., Jeschke, R., Muller, O., Back, W. and Zimmer, M. (1998) Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nat. Genet., 18, 38-43.
-
(1998)
Nat. Genet.
, vol.18
, pp. 38-43
-
-
Jenne, D.E.1
Reimann, H.2
Nezu, J.3
Friedel, W.4
Loff, S.5
Jeschke, R.6
Muller, O.7
Back, W.8
Zimmer, M.9
-
5
-
-
67749111502
-
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
-
Shackelford, D.B. and Shaw, R.J. (2009) The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat. Rev. Cancer, [9,] 563-575.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 563-575
-
-
Shackelford, D.B.1
Shaw, R.J.2
-
6
-
-
80052511813
-
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
-
Mihaylova, M.M. and Shaw, R.J. (2011) The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat. Cell Biol., 13, 1016-1023.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1016-1023
-
-
Mihaylova, M.M.1
Shaw, R.J.2
-
7
-
-
34447342867
-
Intratubular large cell hyalinizing Sertoli cell neoplasia of the testis: a report of 8 cases of a distinctive lesion of the Peutz-Jeghers syndrome
-
Ulbright, T.M., Amin, M.B. and Young, R.H. (2007) Intratubular large cell hyalinizing Sertoli cell neoplasia of the testis: a report of 8 cases of a distinctive lesion of the Peutz-Jeghers syndrome. Am. J. Surg. Pathol., 31, 827-835.
-
(2007)
Am. J. Surg. Pathol.
, vol.31
, pp. 827-835
-
-
Ulbright, T.M.1
Amin, M.B.2
Young, R.H.3
-
8
-
-
0028888507
-
Feminizing Sertoli cell tumors in boys with Peutz-Jeghers syndrome
-
Young, S., Gooneratne, S., Straus, F.H. II, Zeller, W.P., Bulun, S.E. and Rosenthal, I.M. (1995) Feminizing Sertoli cell tumors in boys with Peutz-Jeghers syndrome. Am. J. Surg. Pathol., 19, 50-58.
-
(1995)
Am. J. Surg. Pathol.
, vol.19
, pp. 50-58
-
-
Young, S.1
Gooneratne, S.2
Straus II, F.H.3
Zeller, W.P.4
Bulun, S.E.5
Rosenthal, I.M.6
-
9
-
-
0034816702
-
Sertoli cell proliferations of the infantile testis: an intratubular form of Sertoli cell tumor?
-
Venara, M., Rey, R., Bergada, I., Mendilaharzu, H., Campo, S. and Chemes, H. (2001) Sertoli cell proliferations of the infantile testis: an intratubular form of Sertoli cell tumor? Am. J. Surg. Pathol., 25, 1237-1244.
-
(2001)
Am. J. Surg. Pathol.
, vol.25
, pp. 1237-1244
-
-
Venara, M.1
Rey, R.2
Bergada, I.3
Mendilaharzu, H.4
Campo, S.5
Chemes, H.6
-
10
-
-
54949102311
-
Regulation of spermatogonial stem cell self-renewal in mammals
-
Oatley, J.M. and Brinster, R.L. (2008) Regulation of spermatogonial stem cell self-renewal in mammals. Annu. Rev. Cell Dev. Biol. 24, 263-286.
-
(2008)
Annu. Rev. Cell Dev. Biol.
, vol.24
, pp. 263-286
-
-
Oatley, J.M.1
Brinster, R.L.2
-
11
-
-
80052550535
-
Sertoli cellspecific deletion of the androgen receptor compromises testicular immune privilege in mice
-
Meng, J., Greenlee, A.R., Taub, C.J. and Braun, R.E. (2011) Sertoli cellspecific deletion of the androgen receptor compromises testicular immune privilege in mice. Biol. Reprod., 85, 254-260.
-
(2011)
Biol. Reprod.
, vol.85
, pp. 254-260
-
-
Meng, J.1
Greenlee, A.R.2
Taub, C.J.3
Braun, R.E.4
-
12
-
-
77952770903
-
Sertoligerm cell junctions in the testis: a review of recent data
-
Kopera, I.A., Bilinska, B., Cheng, C.Y. and Mruk, D.D. (2010) Sertoligerm cell junctions in the testis: a review of recent data. Philos. Trans. R. Soc. Lond. B. Biol. Sci., 365, 1593-1605.
-
(2010)
Philos. Trans. R. Soc. Lond. B. Biol. Sci.
, vol.365
, pp. 1593-1605
-
-
Kopera, I.A.1
Bilinska, B.2
Cheng, C.Y.3
Mruk, D.D.4
-
13
-
-
80053365132
-
Adenomatous polyposis coli (APC) is essential for maintaining the integrity of the seminiferous epithelium
-
Tanwar, P.S., Zhang, L. and Teixeira, J.M. (2011) Adenomatous polyposis coli (APC) is essential for maintaining the integrity of the seminiferous epithelium. Mol. Endocrinol., 25, 1725-1739.
-
(2011)
Mol. Endocrinol.
, vol.25
, pp. 1725-1739
-
-
Tanwar, P.S.1
Zhang, L.2
Teixeira, J.M.3
-
14
-
-
20044370885
-
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
-
Sakamoto, K., McCarthy, A., Smith, D., Green, K.A., Grahame Hardie, D., Ashworth, A. and Alessi, D.R. (2005) Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction. EMBO J., 24, 1810-1820.
-
(2005)
EMBO J
, vol.24
, pp. 1810-1820
-
-
Sakamoto, K.1
McCarthy, A.2
Smith, D.3
Green, K.A.4
Grahame Hardie, D.5
Ashworth, A.6
Alessi, D.R.7
-
15
-
-
83455245205
-
The tumor suppressor kinase LKB1: lessons from mouse models
-
Ollila, S. and Makela, T.P. (2011) The tumor suppressor kinase LKB1: lessons from mouse models. J. Mol. Cell Biol., 3, 330-340.
-
(2011)
J. Mol. Cell Biol.
, vol.3
, pp. 330-340
-
-
Ollila, S.1
Makela, T.P.2
-
16
-
-
56049117647
-
A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis
-
Towler, M.C., Fogarty, S., Hawley, S.A., Pan, D.A., Martin, D.M., Morrice, N.A., McCarthy, A., Galardo, M.N., Meroni, S.B., Cigorraga, S.B. et al. (2008) A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis. Biochem. J., 416, 1-14.
-
(2008)
Biochem. J.
, vol.416
, pp. 1-14
-
-
Towler, M.C.1
Fogarty, S.2
Hawley, S.A.3
Pan, D.A.4
Martin, D.M.5
Morrice, N.A.6
McCarthy, A.7
Galardo, M.N.8
Meroni, S.B.9
Cigorraga, S.B.10
-
17
-
-
82455186310
-
LKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testis
-
Denison, F.C., Smith, L.B., Muckett, P.J., O'Hara, L., Carling, D. and Woods, A. (2011) LKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testis. PLoS One, 6, pe28306.
-
(2011)
PLoS One
, vol.6
-
-
Denison, F.C.1
Smith, L.B.2
Muckett, P.J.3
O'Hara, L.4
Carling, D.5
Woods, A.6
-
18
-
-
0036737212
-
Microtubules of the mouse testis exhibit differential sensitivity to the microtubule disruptors Carbendazim and colchicine
-
Correa, L.M., Nakai, M., Strandgaard, C.S., Hess, R.A. and Miller, M.G. [2002(] Microtubules of the mouse testis exhibit differential sensitivity to the microtubule disruptors Carbendazim and colchicine. Toxicol. Sci., 69, 175-182.
-
(2002)
Toxicol. Sci.
, vol.69
, pp. 175-182
-
-
Correa, L.M.1
Nakai, M.2
Strandgaard, C.S.3
Hess, R.A.4
Miller, M.G.5
-
19
-
-
0028223562
-
Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice
-
2nd
-
Enders, G.C. and May, J.J. 2nd (1994) Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice. Dev. Biol., 163, 331-340.
-
(1994)
Dev. Biol.
, vol.163
, pp. 331-340
-
-
Enders, G.C.1
May, J.J.2
-
20
-
-
77950355151
-
Constitutive WNT/beta-catenin signaling in murine Sertoli cells disrupts their differentiation and ability to support spermatogenesis
-
Tanwar, P.S., Kaneko-Tarui, T., Zhang, L., Rani, P., Taketo, M.M. and Teixeira, J. (2010) Constitutive WNT/beta-catenin signaling in murine Sertoli cells disrupts their differentiation and ability to support spermatogenesis. Biol. Reprod., 82, 422-432.
-
(2010)
Biol. Reprod.
, vol.82
, pp. 422-432
-
-
Tanwar, P.S.1
Kaneko-Tarui, T.2
Zhang, L.3
Rani, P.4
Taketo, M.M.5
Teixeira, J.6
-
21
-
-
50849114858
-
Seminiferous tubule degeneration and infertility in mice with sustained activation of WNT/CTNNB1 signaling in sertoli cells
-
Boyer, A., Hermo, L., Paquet, M., Robaire, B. and Boerboom, D. (2008) Seminiferous tubule degeneration and infertility in mice with sustained activation of WNT/CTNNB1 signaling in sertoli cells. Biol. Reprod., 79, 475-485.
-
(2008)
Biol. Reprod.
, vol.79
, pp. 475-485
-
-
Boyer, A.1
Hermo, L.2
Paquet, M.3
Robaire, B.4
Boerboom, D.5
-
22
-
-
44849092121
-
A mesenchymal perspective of Mullerian duct differentiation and regression in Amhr2-lacZ mice
-
Arango, N.A., Kobayashi, A., Wang, Y., Jamin, S.P., Lee, H.H., Orvis, G.D. and Behringer, R.R. (2008) A mesenchymal perspective of Mullerian duct differentiation and regression in Amhr2-lacZ mice. Mol. Reprod. Dev., 75, 1154-1162.
-
(2008)
Mol. Reprod. Dev.
, vol.75
, pp. 1154-1162
-
-
Arango, N.A.1
Kobayashi, A.2
Wang, Y.3
Jamin, S.P.4
Lee, H.H.5
Orvis, G.D.6
Behringer, R.R.7
-
23
-
-
78651451766
-
GATA4 regulates Sertoli cell function and fertility in adult male mice
-
Kyronlahti, A., Euler, R., Bielinska, M., Schoeller, E.L., Moley, K.H., Toppari, J., Heikinheimo, M. and Wilson, D.B. (2011) GATA4 regulates Sertoli cell function and fertility in adult male mice. Mol. Cell. Endocrinol., 333, 85-95.
-
(2011)
Mol. Cell. Endocrinol.
, vol.333
, pp. 85-95
-
-
Kyronlahti, A.1
Euler, R.2
Bielinska, M.3
Schoeller, E.L.4
Moley, K.H.5
Toppari, J.6
Heikinheimo, M.7
Wilson, D.B.8
-
24
-
-
84861503495
-
NR5A1 is required for functional maturation of Sertoli cells during postnatal development
-
Kato, T., Esaki, M., Matsuzawa, A. and Ikeda, Y. (2012) NR5A1 is required for functional maturation of Sertoli cells during postnatal development. Reproduction, 143, 663-672.
-
(2012)
Reproduction
, vol.143
, pp. 663-672
-
-
Kato, T.1
Esaki, M.2
Matsuzawa, A.3
Ikeda, Y.4
-
26
-
-
71849115693
-
Regulation of spermatogenesis in the microenvironment of the seminiferous epithelium: new insights and advances
-
Cheng, C.Y., Wong, E.W., Yan, H.H. and Mruk, D.D. (2010) Regulation of spermatogenesis in the microenvironment of the seminiferous epithelium: new insights and advances. Mol. Cell. Endocrinol., 315, 49-56.
-
(2010)
Mol. Cell. Endocrinol.
, vol.315
, pp. 49-56
-
-
Cheng, C.Y.1
Wong, E.W.2
Yan, H.H.3
Mruk, D.D.4
-
27
-
-
0041758428
-
Tuberous sclerosis: from tubers to mTOR
-
Kwiatkowski, D.J. (2003) Tuberous sclerosis: from tubers to mTOR. Ann. Hum. Genet., 67, 87-96.
-
(2003)
Ann. Hum. Genet.
, vol.67
, pp. 87-96
-
-
Kwiatkowski, D.J.1
-
28
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw, D., Marsh, D.J., Li, J., Dahia, P.L., Wang, S.I., Zheng, Z., Bose, S., Call, K.M., Tsou, H.C., Peacocke, M. et al. (1997) Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet., 16, 64-67.
-
(1997)
Nat. Genet.
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
-
29
-
-
0036501277
-
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and upregulation of p70S6 kinase activity in Tsc1 null cells
-
Kwiatkowski, D.J., Zhang, H., Bandura, J.L., Heiberger, K.M., Glogauer, M., el-Hashemite, N. and Onda, H. (2002) A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and upregulation of p70S6 kinase activity in Tsc1 null cells. Hum. Mol. Genet., [11,] 525-534.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 525-534
-
-
Kwiatkowski, D.J.1
Zhang, H.2
Bandura, J.L.3
Heiberger, K.M.4
Glogauer, M.5
el-Hashemite, N.6
Onda, H.7
-
30
-
-
3142594193
-
The LKB1 tumor suppressor negatively regulates mTOR signaling
-
Shaw, R.J., Bardeesy, N., Manning, B.D., Lopez, L., Kosmatka, M., DePinho, R.A. and Cantley, L.C. (2004) The LKB1 tumor suppressor negatively regulates mTOR signaling. Cancer Cell, 6, 91-99.
-
(2004)
Cancer Cell
, vol.6
, pp. 91-99
-
-
Shaw, R.J.1
Bardeesy, N.2
Manning, B.D.3
Lopez, L.4
Kosmatka, M.5
DePinho, R.A.6
Cantley, L.C.7
-
31
-
-
17944368972
-
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten + /-mice
-
Podsypanina, K., Lee, R.T., Politis, C., Hennessy, I., Crane, A., Puc, J., Neshat, M., Wang, H., Yang, L., Gibbons, J. et al. (2001) An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten + /- mice. Proc. Natl. Acad. Sci. U. S. A., 98, 10320-10325.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 10320-10325
-
-
Podsypanina, K.1
Lee, R.T.2
Politis, C.3
Hennessy, I.4
Crane, A.5
Puc, J.6
Neshat, M.7
Wang, H.8
Yang, L.9
Gibbons, J.10
-
32
-
-
0242268407
-
mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo
-
Kwon, C.H., Zhu, X., Zhang, J. and Baker, S.J. (2003) mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo. Proc. Natl. Acad. Sci. U. S. A., 100, 12923-12928
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 12923-12928
-
-
Kwon, C.H.1
Zhu, X.2
Zhang, J.3
Baker, S.J.4
-
33
-
-
3042818799
-
Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome
-
Corradetti, M.N., Inoki, K., Bardeesy, N., DePinho, R.A. and Guan, K.L. [2004(] Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome. Genes Dev., 18, 1533-1538.
-
(2004)
Genes Dev
, vol.18
, pp. 1533-1538
-
-
Corradetti, M.N.1
Inoki, K.2
Bardeesy, N.3
DePinho, R.A.4
Guan, K.L.5
-
34
-
-
80053211264
-
Polarity proteins and actin regulatory proteins are unlikely partners that regulate cell adhesion in the seminiferous epithelium during spermatogenesis
-
Cheng, C.Y., Wong, E.W., Lie, P.P., Mruk, D.D., Xiao, X., Li, M.W., Lui, W.Y. and Lee, W.M. (2011) Polarity proteins and actin regulatory proteins are unlikely partners that regulate cell adhesion in the seminiferous epithelium during spermatogenesis. Histol. Histopathol., 26, 1465-1474.
-
(2011)
Histol. Histopathol.
, vol.26
, pp. 1465-1474
-
-
Cheng, C.Y.1
Wong, E.W.2
Lie, P.P.3
Mruk, D.D.4
Xiao, X.5
Li, M.W.6
Lui, W.Y.7
Lee, W.M.8
-
35
-
-
33846521353
-
Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
-
Zheng, B. and Cantley, L.C. (2007) Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase. Proc. Natl. Acad. Sci. U. S. A., 104, 819-822.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 819-822
-
-
Zheng, B.1
Cantley, L.C.2
-
36
-
-
33751204464
-
AMP-activated protein kinase regulates the assembly of epithelial tight junctions
-
Zhang, L., Li, J., Young, L.H. and Caplan, M.J. (2006) AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proc. Natl. Acad. Sci. U. S. A., 103, 17272-17277.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 17272-17277
-
-
Zhang, L.1
Li, J.2
Young, L.H.3
Caplan, M.J.4
-
37
-
-
78149259013
-
Primary cilia regulate mTORC1 activity and cell size through Lkb1
-
Boehlke, C., Kotsis, F., Patel, V., Braeg, S., Voelker, H., Bredt, S., Beyer, T., Janusch, H., Hamann, C., Godel, M. et al. (2010) Primary cilia regulate mTORC1 activity and cell size through Lkb1. Nat. Cell Biol., 12, 1115-1122.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 1115-1122
-
-
Boehlke, C.1
Kotsis, F.2
Patel, V.3
Braeg, S.4
Voelker, H.5
Bredt, S.6
Beyer, T.7
Janusch, H.8
Hamann, C.9
Godel, M.10
-
38
-
-
79955044493
-
AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress
-
Williams, T., Courchet, J., Viollet, B., Brenman, J.E. and Polleux, F. [2011(] AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress. Proc. Natl. Acad. Sci. U. S. A., 108, 5849-5854.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 5849-5854
-
-
Williams, T.1
Courchet, J.2
Viollet, B.3
Brenman, J.E.4
Polleux, F.5
-
39
-
-
34548179000
-
Suppression of tubulin polymerization by the LKB1-microtubule-associated protein/microtubule affinity-regulating kinase signaling
-
Kojima, Y., Miyoshi, H., Clevers, H.C., Oshima, M., Aoki, M. and Taketo, M.M. (2007) Suppression of tubulin polymerization by the LKB1-microtubule-associated protein/microtubule affinity-regulating kinase signaling. J. Biol. Chem., 282, 23532-23540.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23532-23540
-
-
Kojima, Y.1
Miyoshi, H.2
Clevers, H.C.3
Oshima, M.4
Aoki, M.5
Taketo, M.M.6
-
40
-
-
14244251499
-
Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate
-
Jaleel, M., McBride, A., Lizcano, J.M., Deak, M., Toth, R., Morrice, N.A. and Alessi, D.R. (2005) Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate. FEBS Lett., 579, 1417-1423.
-
(2005)
FEBS Lett
, vol.579
, pp. 1417-1423
-
-
Jaleel, M.1
McBride, A.2
Lizcano, J.M.3
Deak, M.4
Toth, R.5
Morrice, N.A.6
Alessi, D.R.7
-
41
-
-
77953305755
-
LKB1 suppresses pp21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the pp21-binding domain
-
Deguchi, A., Miyoshi, H., Kojima, Y., Okawa, K., Aoki, M. and Taketo, M.M. (2010) LKB1 suppresses pp21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the pp21-binding domain. J. Biol. Chem., [285,] 18283-18290.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 18283-18290
-
-
Deguchi, A.1
Miyoshi, H.2
Kojima, Y.3
Okawa, K.4
Aoki, M.5
Taketo, M.M.6
-
42
-
-
33645531880
-
TEX14 is essential for intercellular bridges and fertility in male mice
-
Greenbaum, M.P., Yan, W., Wu, M.H., Lin, Y.N., Agno, J.E., Sharma, M., Braun, R.E., Rajkovic, A. and Matzuk, M.M. (2006) TEX14 is essential for intercellular bridges and fertility in male mice. Proc. Natl. Acad. Sci. U. S. A., 103, 4982-4987.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 4982-4987
-
-
Greenbaum, M.P.1
Yan, W.2
Wu, M.H.3
Lin, Y.N.4
Agno, J.E.5
Sharma, M.6
Braun, R.E.7
Rajkovic, A.8
Matzuk, M.M.9
-
43
-
-
0037125996
-
Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis
-
Rossi, D.J., Ylikorkala, A., Korsisaari, N., Salovaara, R., Luukko, K., Launonen, V., Henkemeyer, M., Ristimaki, A., Aaltonen, L.A. and Makela, T.P. (2002) Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis. Proc. Natl. Acad. Sci. U. S. A., 99, 12327-12332.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 12327-12332
-
-
Rossi, D.J.1
Ylikorkala, A.2
Korsisaari, N.3
Salovaara, R.4
Luukko, K.5
Launonen, V.6
Henkemeyer, M.7
Ristimaki, A.8
Aaltonen, L.A.9
Makela, T.P.10
-
44
-
-
77953238558
-
Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors
-
Carretero, J., Shimamura, T., Rikova, K., Jackson, A.L., Wilkerson, M.D., Borgman, C.L., Buttarazzi, M.S., Sanofsky, B.A., McNamara, K.L., Brandstetter, K.A. et al. (2010) Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors. Cancer Cell, 17, 547-559.
-
(2010)
Cancer Cell
, vol.17
, pp. 547-559
-
-
Carretero, J.1
Shimamura, T.2
Rikova, K.3
Jackson, A.L.4
Wilkerson, M.D.5
Borgman, C.L.6
Buttarazzi, M.S.7
Sanofsky, B.A.8
McNamara, K.L.9
Brandstetter, K.A.10
-
45
-
-
63449118489
-
Mitogen-activated protein kinases in male reproductive function
-
Li, M.W., Mruk, D.D. and Cheng, C.Y. (2009) Mitogen-activated protein kinases in male reproductive function. Trends Mol Med, 15, 159-168.
-
(2009)
Trends Mol Med
, vol.15
, pp. 159-168
-
-
Li, M.W.1
Mruk, D.D.2
Cheng, C.Y.3
-
46
-
-
67249083120
-
Focal adhesion kinase is a blood-testis barrier regulator
-
Siu, E.R., Wong, E.W., Mruk, D.D., Porto, C.S. and Cheng, C.Y. (2009) Focal adhesion kinase is a blood-testis barrier regulator. Proc. Natl. Acad. Sci. U. S. A., 106, 9298-9303.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 9298-9303
-
-
Siu, E.R.1
Wong, E.W.2
Mruk, D.D.3
Porto, C.S.4
Cheng, C.Y.5
-
47
-
-
19044391626
-
TGF-beta3 regulates anchoring junction dynamics in the seminiferous epithelium of the rat testis via the Ras/ERK signaling pathway: an in vivo study
-
Xia, W. and Cheng, C.Y. (2005) TGF-beta3 regulates anchoring junction dynamics in the seminiferous epithelium of the rat testis via the Ras/ERK signaling pathway: an in vivo study. Dev. Biol., 280, 321-343.
-
(2005)
Dev. Biol.
, vol.280
, pp. 321-343
-
-
Xia, W.1
Cheng, C.Y.2
-
48
-
-
79951711094
-
Regulation of Sertoli-germ cell adhesion and sperm release by FSH and nonclassical testosterone signaling
-
Shupe, J., Cheng, J., Puri, P., Kostereva, N. and Walker, W.H. (2011) Regulation of Sertoli-germ cell adhesion and sperm release by FSH and nonclassical testosterone signaling. Mol. Endocrinol., 25, 238-252.
-
(2011)
Mol. Endocrinol.
, vol.25
, pp. 238-252
-
-
Shupe, J.1
Cheng, J.2
Puri, P.3
Kostereva, N.4
Walker, W.H.5
-
49
-
-
0020594215
-
Threedimensional reconstruction of a rat stage V Sertoli cell: II Morphometry of Sertoli-Sertoli and Sertoli-germ-cell relationships
-
Weber, J.E., Russell, L.D., Wong, V. and Peterson, R.N. (1983) Threedimensional reconstruction of a rat stage V Sertoli cell: II. Morphometry of Sertoli-Sertoli and Sertoli-germ-cell relationships. Am. J. Anat., 167, 163-179.
-
(1983)
Am. J. Anat.
, vol.167
, pp. 163-179
-
-
Weber, J.E.1
Russell, L.D.2
Wong, V.3
Peterson, R.N.4
-
50
-
-
0033995832
-
Developmental expression of thyroid hormone receptors in the rat testis
-
Buzzard, J.J., Morrison, J.R., O'Bryan, M.K., Song, Q. and Wreford, N.G. [2000(] Developmental expression of thyroid hormone receptors in the rat testis. Biol. Reprod., 62, 664-669.
-
(2000)
Biol. Reprod.
, vol.62
, pp. 664-669
-
-
Buzzard, J.J.1
Morrison, J.R.2
O'Bryan, M.K.3
Song, Q.4
Wreford, N.G.5
-
51
-
-
84867117848
-
Thyroid hormone limits postnatal sertoli cell proliferation in vivo by activation of its Alpha1 Isoform Receptor (TRalpha1) present in these cells and by regulation of Cdk4/JunD/c-myc mRNA levels in mice
-
(published ahead of print April 25, 2012 doi:10 1095/biolreprod. 111. 098418)
-
Fumel, B., Guerquin, M.J., Livera, G., Staub, C., Magistrini, M., Gauthier, C., Flamant, F., Guillou, F. and Fouchecourt, S. (2012) Thyroid hormone limits postnatal sertoli cell proliferation in vivo by activation of its Alpha1 Isoform Receptor (TRalpha1) present in these cells and by regulation of Cdk4/JunD/c-myc mRNA levels in mice. Biol. Reprod (published ahead of print April 25, 2012, doi:10.1095/biolreprod.111.098418).
-
(2012)
Biol. Reprod.
-
-
Fumel, B.1
Guerquin, M.J.2
Livera, G.3
Staub, C.4
Magistrini, M.5
Gauthier, C.6
Flamant, F.7
Guillou, F.8
Fouchecourt, S.9
-
52
-
-
37149042642
-
A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome
-
Sanchez-Cespedes, M. (2007) A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome. Oncogene, 26, 7825-7832.
-
(2007)
Oncogene
, vol.26
, pp. 7825-7832
-
-
Sanchez-Cespedes, M.1
-
53
-
-
79953239478
-
LKB1 loss of function studied in vivo
-
Shorning, B.Y. and Clarke, A.R. (2011) LKB1 loss of function studied in vivo. FEBS Lett., 585, 958-966.
-
(2011)
FEBS Lett
, vol.585
, pp. 958-966
-
-
Shorning, B.Y.1
Clarke, A.R.2
-
54
-
-
0032906537
-
Mutations and impaired function of LKB1 in familial and nonfamilial Peutz-Jeghers syndrome and a sporadic testicular cancer
-
Ylikorkala, A., Avizienyte, E., Tomlinson, I.P., Tiainen, M., Roth, S., Loukola, A., Hemminki, A., Johansson, M., Sistonen, P., Markie, D. et al. [1999(] Mutations and impaired function of LKB1 in familial and nonfamilial Peutz-Jeghers syndrome and a sporadic testicular cancer. Hum. Mol. Genet., 8, 45-51.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 45-51
-
-
Ylikorkala, A.1
Avizienyte, E.2
Tomlinson, I.P.3
Tiainen, M.4
Roth, S.5
Loukola, A.6
Hemminki, A.7
Johansson, M.8
Sistonen, P.9
Markie, D.10
-
55
-
-
0034610730
-
Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome
-
Esteller, M., Avizienyte, E., Corn, P.G., Lothe, R.A., Baylin, S.B., Aaltonen, L.A. and Herman, J.G. (2000) Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome. Oncogene, [19,] 164-168.
-
(2000)
Oncogene
, vol.19
, pp. 164-168
-
-
Esteller, M.1
Avizienyte, E.2
Corn, P.G.3
Lothe, R.A.4
Baylin, S.B.5
Aaltonen, L.A.6
Herman, J.G.7
-
56
-
-
84857132136
-
Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity
-
Partanen, J.I., Tervonen, T.A., Myllynen, M., Lind, E., Imai, M., Katajisto, P., Dijkgraaf, G.J., Kovanen, P.E., Makela, T.P., Werb, Z. et al. [2012(] Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity.. Proc. Natl. Acad. Sci. U. S. A., 109, E388-E397.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
-
-
Partanen, J.I.1
Tervonen, T.A.2
Myllynen, M.3
Lind, E.4
Imai, M.5
Katajisto, P.6
Dijkgraaf, G.J.7
Kovanen, P.E.8
Makela, T.P.9
Werb, Z.10
-
57
-
-
51949094890
-
Tuberous sclerosis complex proteins control axon formation
-
Choi, Y.J., Di Nardo, A., Kramvis, I., Meikle, L., Kwiatkowski, D.J., Sahin, M. and He, X. (2008) Tuberous sclerosis complex proteins control axon formation. Genes Dev., 22, 2485-2495.
-
(2008)
Genes Dev
, vol.22
, pp. 2485-2495
-
-
Choi, Y.J.1
Di Nardo, A.2
Kramvis, I.3
Meikle, L.4
Kwiatkowski, D.J.5
Sahin, M.6
He, X.7
-
58
-
-
66149098514
-
Defects in cell polarity underlie TSC and ADPKDassociated cystogenesis
-
Bonnet, C.S., Aldred, M., von Ruhland, C., Harris, R., Sandford, R. and Cheadle, J.P. (2009) Defects in cell polarity underlie TSC and ADPKDassociated cystogenesis. Hum. Mol. Genet., 18, 2166-2176.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 2166-2176
-
-
Bonnet, C.S.1
Aldred, M.2
von Ruhland, C.3
Harris, R.4
Sandford, R.5
Cheadle, J.P.6
-
59
-
-
78650510609
-
mTOR: from growth signal integration to cancer, diabetes and ageing
-
Zoncu, R., Efeyan, A. and Sabatini, D.M. (2011) mTOR: from growth signal integration to cancer, diabetes and ageing. Nat. Rev. Mol. Cell Biol., [12,] 21-35.
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
-
60
-
-
84856428465
-
Testicular cancer and the tuberous sclerosis complex
-
Tandstad, T. and Indrebo, G. (2012) Testicular cancer and the tuberous sclerosis complex. Acta Oncol., 51, 262-265.
-
(2012)
Acta Oncol
, vol.51
, pp. 262-265
-
-
Tandstad, T.1
Indrebo, G.2
-
61
-
-
0027328012
-
Benign Leydig cell tumor of the testis associated with human papillomavirus type [33] presenting with the sign of Leser-Trelat
-
Martin, R.W. III, Rady, P., Arany, I. and Tyring, S.K. (1993) Benign Leydig cell tumor of the testis associated with human papillomavirus type [33] presenting with the sign of Leser-Trelat. J. Urol., 150, 1246-1250.
-
(1993)
J. Urol.
, vol.150
, pp. 1246-1250
-
-
Martin III, R.W.1
Rady, P.2
Arany, I.3
Tyring, S.K.4
-
62
-
-
24944480788
-
The Akt-mTOR tango and its relevance to cancer
-
Hay, N. (2005) The Akt-mTOR tango and its relevance to cancer. Cancer Cell, 8, 179-183.
-
(2005)
Cancer Cell
, vol.8
, pp. 179-183
-
-
Hay, N.1
-
63
-
-
70350688091
-
Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1
-
Zhou, J., Brugarolas, J. and Parada, L.F. (2009) Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1. Hum. Mol. Genet., 18, 4428-4441.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 4428-4441
-
-
Zhou, J.1
Brugarolas, J.2
Parada, L.F.3
-
64
-
-
23944483709
-
ERM is required for transcriptional control of the spermatogonial stem cell niche
-
Chen, C., Ouyang, W., Grigura, V., Zhou, Q., Carnes, K., Lim, H., Zhao, G.Q., Arber, S., Kurpios, N., Murphy, T.L. et al. (2005) ERM is required for transcriptional control of the spermatogonial stem cell niche. Nature, [436,] 1030-1034.
-
(2005)
Nature
, vol.436
, pp. 1030-1034
-
-
Chen, C.1
Ouyang, W.2
Grigura, V.3
Zhou, Q.4
Carnes, K.5
Lim, H.6
Zhao, G.Q.7
Arber, S.8
Kurpios, N.9
Murphy, T.L.10
-
65
-
-
33646696207
-
The first round of mouse spermatogenesis is a distinctive program that lacks the self-renewing spermatogonia stage
-
Yoshida, S., Sukeno, M., Nakagawa, T., Ohbo, K., Nagamatsu, G., Suda, T. and Nabeshima, Y. (2006) The first round of mouse spermatogenesis is a distinctive program that lacks the self-renewing spermatogonia stage. Development, 133, 1495-1505.
-
(2006)
Development
, vol.133
, pp. 1495-1505
-
-
Yoshida, S.1
Sukeno, M.2
Nakagawa, T.3
Ohbo, K.4
Nagamatsu, G.5
Suda, T.6
Nabeshima, Y.7
-
66
-
-
0742323949
-
Increased apoptosis occurring during the first wave of spermatogenesis is stage-specific and primarily affects midpachytene spermatocytes in the rat testis
-
Jahnukainen, K., Chrysis, D., Hou, M., Parvinen, M., Eksborg, S. and Soder, O. (2004) Increased apoptosis occurring during the first wave of spermatogenesis is stage-specific and primarily affects midpachytene spermatocytes in the rat testis. Biol. Reprod., 70, 290-296.
-
(2004)
Biol. Reprod.
, vol.70
, pp. 290-296
-
-
Jahnukainen, K.1
Chrysis, D.2
Hou, M.3
Parvinen, M.4
Eksborg, S.5
Soder, O.6
-
67
-
-
0036842115
-
Requirement of Bmpr1a for Mullerian duct regression during male sexual development
-
Jamin, S.P., Arango, N.A., Mishina, Y., Hanks, M.C. and Behringer, R.R. [2002(] Requirement of Bmpr1a for Mullerian duct regression during male sexual development. Nat. Genet., 32, 408-410.
-
(2002)
Nat. Genet.
, vol.32
, pp. 408-410
-
-
Jamin, S.P.1
Arango, N.A.2
Mishina, Y.3
Hanks, M.C.4
Behringer, R.R.5
-
68
-
-
0037068461
-
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
-
Bardeesy, N., Sinha, M., Hezel, A.F., Signoretti, S., Hathaway, N.A., Sharpless, N.E., Loda, M., Carrasco, D.R. and DePinho, R.A. (2002) Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation. Nature, 419, 162-167.
-
(2002)
Nature
, vol.419
, pp. 162-167
-
-
Bardeesy, N.1
Sinha, M.2
Hezel, A.F.3
Signoretti, S.4
Hathaway, N.A.5
Sharpless, N.E.6
Loda, M.7
Carrasco, D.R.8
DePinho, R.A.9
-
69
-
-
33947180978
-
Generation of a conditional disruption of the Tsc2 gene
-
Hernandez, O., Way, S., McKenna, J. III and Gambello, M.J. (2007) Generation of a conditional disruption of the Tsc2 gene. Genesis, 45, 101-106.
-
(2007)
Genesis
, vol.45
, pp. 101-106
-
-
Hernandez, O.1
Way, S.2
McKenna III, J.3
Gambello, M.J.4
-
70
-
-
0036195102
-
Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene
-
Lesche, R., Groszer, M., Gao, J., Wang, Y., Messing, A., Sun, H., Liu, X. and Wu, H. (2002) Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis, 32, 148-149.
-
(2002)
Genesis
, vol.32
, pp. 148-149
-
-
Lesche, R.1
Groszer, M.2
Gao, J.3
Wang, Y.4
Messing, A.5
Sun, H.6
Liu, X.7
Wu, H.8
-
71
-
-
84455185089
-
Deletion of tuberous sclerosis 1 in somatic cells of the murine reproductive tract causes female infertility
-
Tanaka, Y., Park, J.H., Tanwar, P.S., Kaneko-Tarui, T., Mittal, S., Lee, H.J. and Teixeira, J.M. (2012) Deletion of tuberous sclerosis 1 in somatic cells of the murine reproductive tract causes female infertility. Endocrinology, 153, 404-416.
-
(2012)
Endocrinology
, vol.153
, pp. 404-416
-
-
Tanaka, Y.1
Park, J.H.2
Tanwar, P.S.3
Kaneko-Tarui, T.4
Mittal, S.5
Lee, H.J.6
Teixeira, J.M.7
-
72
-
-
28244487293
-
Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium
-
Arango, N.A., Szotek, P.P., Manganaro, T.F., Oliva, E., Donahoe, P.K. and Teixeira, J. (2005) Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium. Dev. Biol., 288, 276-283.
-
(2005)
Dev. Biol.
, vol.288
, pp. 276-283
-
-
Arango, N.A.1
Szotek, P.P.2
Manganaro, T.F.3
Oliva, E.4
Donahoe, P.K.5
Teixeira, J.6
-
73
-
-
77958009978
-
Focal Mullerian duct retention in male mice with constitutively activated {beta}-catenin expression in the Mullerian duct mesenchyme
-
U. S. A
-
Tanwar, P.S., Zhang, L., Tanaka, Y., Taketo, M.M., Donahoe, P.K. and Teixeira, J.M. (2010) Focal Mullerian duct retention in male mice with constitutively activated {beta}-catenin expression in the Mullerian duct mesenchyme. Proc. Natl. Acad. Sci. U. S. A.
-
(2010)
Proc. Natl. Acad. Sci
-
-
Tanwar, P.S.1
Zhang, L.2
Tanaka, Y.3
Taketo, M.M.4
Donahoe, P.K.5
Teixeira, J.M.6
|