LKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domain

Journal of Biological Chemistry

Volumn 285, Issue 24, 2010, Pages 18283-18290

  Deguchi, Atsuko ^a   Miyoshi, Hiroyuki ^a   Kojima, Yasushi ^a   Okawa, Katsuya ^b   Aoki, Masahiro ^a   Taketo, Makoto M ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING DOMAIN; CELL MIGRATION; CELL MOTILITY; DOWNSTREAM TARGET; HEPATOCELLULAR; HUMAN COLON CANCER; IN-VITRO; MOUSE EMBRYONIC FIBROBLASTS; P-21 ACTIVATED KINASE; PROTEIN KINASE; TUMOR SUPPRESSOR GENES; WILD TYPES;

CELL CULTURE; GROWTH KINETICS; PATHOLOGY; PROTEINS;

PHOSPHORYLATION;

P21 ACTIVATED KINASE 1; PROTEIN KINASE LKB1; PROTEIN P21; THREONINE;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL MOTILITY; CELL STRAIN HCT116; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PEUTZ JEGHERS SYNDROME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; WILD TYPE;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; FEMALE; HUMANS; MALE; MICE; MICE, KNOCKOUT; NEOPLASMS; P21-ACTIVATED KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; THREONINE;

MUS;

EID: 77953305755     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.079137     Document Type: Article

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