The Impact of Extracorporeal Life Support and Hypothermia on Drug Disposition in Critically Ill Infants and Children

Pediatric Clinics of North America

Volumn 59, Issue 5, 2012, Pages 1183-1204

  Wildschut, Enno D ^a   van Saet, Annewil ^a,b   Pokorna, Pavla ^a,c   Ahsman, Maurice J ^d   Van den Anker, John N ^a,e,f   Tibboel, Dick ^a  

^a SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c CHARLES UNIVERSITY   (Czech Republic)

^d LAPandP Consultants BV   (Netherlands)

^e CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^f GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Analgesia; Extracorporeal membrane oxygenation; Hypothermia; Infant; Pharmacodynamics; Pharmacokinetics; Pharmacology; Sedation

Indexed keywords

AMIODARONE; BUMETANIDE; CASPOFUNGIN; CEFAZOLIN; CEFOTAXIME; CEFUROXIME; CISATRACURIUM; ESMOLOL; FENTANYL; FUROSEMIDE; GENTAMICIN; HEPARIN; MIDAZOLAM; MORPHINE; NESIRITIDE; NICARDIPINE; OSELTAMIVIR; PANCURONIUM; PENTOBARBITAL; PHENOBARBITAL; PHENYTOIN; PROPOFOL; PROSTAGLANDIN E1; RIBAVIRIN; SILDENAFIL; TIMENTIN; UNINDEXED DRUG; VANCOMYCIN; VECURONIUM; VORICONAZOLE;

CARDIOPULMONARY BYPASS; CHILD HEALTH CARE; CONTINUOUS INFUSION; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG DOSE TITRATION; DRUG EFFECT; DRUG ELIMINATION; DRUG MEGADOSE; DRUG METABOLISM; DRUG MONITORING; EXTRACORPOREAL OXYGENATION; HUMAN; INDUCED HYPOTHERMIA; INFLUENZA A (H1N1); LIPOPHILICITY; MINIMUM INHIBITORY CONCENTRATION; NEWBORN SEPSIS; NONHUMAN; OUTCOME ASSESSMENT; PANDEMIC INFLUENZA; REVIEW; THROMBOEMBOLISM;

EID: 84867042097     PISSN: 00313955     EISSN: 15578240     Source Type: Journal    
DOI: 10.1016/j.pcl.2012.07.013     Document Type: Review

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