Systematic intervention to reduce central line-associated bloodstream infection rates in a pediatric cardiac intensive care unit

Pediatrics

Volumn 121, Issue 5, 2008, Pages 915-923

  Costello, John M ^a   Morrow, Debra Forbes ^a   Graham, Dionne A ^a   Potter Bynoe, Gail ^a   Sandora, Thomas J ^a   Laussen, Peter C ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Bacterial infection; Catheter; Congenital heart defect; Infection control; Nosocomial infection; Pediatric intensive care units

Indexed keywords

ARTICLE; BLOODSTREAM INFECTION; CHILD; CLINICAL PRACTICE; CONTROLLED STUDY; HOSPITAL ADMISSION; HOSPITAL INFECTION; HOSPITAL PERSONNEL; HUMAN; INFANT; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; PEDIATRICS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; STAFF TRAINING; BACTEREMIA; CENTRAL VENOUS CATHETERIZATION; CORONARY CARE UNIT; CROSS INFECTION; INDWELLING CATHETER; INFECTION CONTROL; INTENSIVE CARE; METHODOLOGY; PRESCHOOL CHILD;

BACTEREMIA; CATHETERIZATION, CENTRAL VENOUS; CATHETERS, INDWELLING; CHILD; CHILD, PRESCHOOL; CORONARY CARE UNITS; CROSS INFECTION; HUMANS; INFANT; INFECTION CONTROL; INTENSIVE CARE UNITS, PEDIATRIC;

EID: 44449154442     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2007-1577     Document Type: Article

References (30)

1. O'Grady NP, Alexander M, Delllnger EP, et al. Guidelines for the prevention of intravascular catheter-related infections. Pediatrics. 2002;110(5). Available at: www.pediatrics.org/cgi/content/full/110/5/e51
2. Pittet D, Tarara D, Wenzel RP. Nosocomial bloodstream infection in critically ill patients: excess length of stay, extra costs, and attributable mortality. JAMA. 1994;271(20):1598-1601
3. Slonim AD, Kurtines HC, Sprague BM, Singh N. The costs associated with nosocomial bloodstream infections in the pediatric intensive care unit. Pediatr Crit Care Med. 2001;2(2):170 -174
4. Grohskopf LA, Sinkowitz-Cochran RL, Garrett DO, et al. A national point-prevalence survey of pediatric intensive care unit-acquired infections in the United States. J Pediatr. 2002; 140(4):432-438
5. National Nosocomial Infections Surveillance System. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control. 2004;32(8):470-485
6. Elward AM, Hollenbeak CS, Warren DK, Fraser VJ. Attributable cost of nosocomial primary bloodstream infection in pediatric intensive care unit patients. Pediatrics. 2005;115(4):868-872
7. Warren DK, Quadir WW, Hollenbeak CS, et al. Attributable cost of catheter-associated bloodstream infections among intensive care patients in a nonteaching hospital. Crit Care Med. 2006;34(8):2084-2089
8. Frankel HL, Crede WB, Topal JE, et al. Use of corporate Six Sigma performance-improvement strategies to reduce incidence of catheter-related bloodstream infections in a surgical ICU. J Am Coll Surg. 2005;201(3):349-358
9. Berenholtz SM, Pronovost PJ, Lipsett PA, et al. Eliminating catheter-related bloodstream infections in the intensive care unit. Crit Care Med. 2004;32(10):2014-2020
10. Centers for Disease Control and Prevention. Reduction in central line-associated bloodstream infections among patients in intensive care units: Pennsylvania, April 2001-March 2005. MMWR Morb Mortal Wkly Rep. 2005;54(40):1013-1016
11. Pronovost P, Needham D, Berenholtz S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med. 2006;355(26):2725-2732
12. Bhutta A, Gilliam C, Honeycutt M, et al. Reduction of bloodstream infections associated withcatheters inpaediatric intensive care unit: stepwise approach. BMJ. 2007;334(7589):362-365
13. Levy I, Ovadia B, Erez E, et al. Nosocomial infections after cardiac surgery in infants and children: incidence and risk factors. J Hosp Infect. 2003;53(2):111-116
14. Shah SS, Kagen J, Lautenbach E, et al. Bloodstream infections after median sternotomy at a children's hospital. J Thorac Cardiovasc Surg. 2007;133(2):435-440
15. Pollock EM, Ford-Jones EL, Rebeyka I, et al. Early nosocomial infections in pediatric cardiovascular surgery patients. Crit Care Med. 1990;18(4):378-384
16. Dagan O, Cox PN, Ford-Jones L, Ponsonby J, Bohn DJ. Nosocomial infection following cardiovascular surgery: comparison of two periods, 1987 vs 1992. Crit Care Med. 1999;27(1):104-108
17. Edwards JR, Peterson KD, Andrus ML, et al. National Healthcare Safety Network (NHSN) Report, data summary for 2006, issued June 2007. Am J Infect Control. 2007;35(5):290-301
18. Yogaraj JS, Elward AM, Fraser VJ. Rate, risk factors, and outcomes of nosocomial primary bloodstream infection in pediatricintensive care unit patients. Pediatrics. 2002;110(3):481-485
19. Urrea M, Pons M, Serra M, Latorre C, Palomeque A. Prospective incidence study of nosocomial infections in a pediatric intensive care unit. Pediatr Infect Dis J. 2003;22(6):490-494
20. Stone SP, Cooper BS, Kibbler CC, et al. The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection. Lancet Infect Dis. 2007;7(4):282-288
21. Sherertz RJ, Ely EW, Westbrook DM, et al. Education of physicians-in-training can decrease the risk for vascular catheter infection. Ann Intern Med. 2000;132(8):641-648
22. Coopersmith CM, Rebmann TL, Zack JE, et al. Effect of an education program on decreasing catheter-related bloodstream infections in the surgical intensive care unit. Crit Care Med. 2002;30(1):59-64
23. Chaiyakunapruk N, Veenstra DL, Lipsky BA, Saint S. Chlorhexidine compared with povidone-iodine solution for vascular catheter-site care: a meta-analysis. Ann Intern Med. 2002;136(11):792-801
24. Horan TC, Gaynes RP. Surveillance of nosocomial infections. In: Mayhall CG, ed. Hospital Epidemiology and Infection Control. Philadelphia, PA: Lippincott, Williams & Wilkins; 2004:1659 -1702
25. Wagner AK, Soumerai SB, Zhang F, Ross-Degnan D. Segmented regression analysis of interrupted time series studies in medication use research. J Clin Pharm Ther. 2002;27(4):299-309
26. Young EM, Commiskey ML, Wilson SJ. Translating evidence into practice to prevent central venous catheter-associated bloodstream infections: a systems-based intervention. Am J Infect Control. 2006;34(8):503-506
27. Mahieu LM, De Dooy JJ, Lenaerts AE, Leven MM, De Muynck AO. Catheter manipulations and the risk of catheter-associated bloodstream infection in neonatal intensive care unit patients. J Hosp Infect. 2001;48(1):20-26
28. van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001;345(19):1359-1367
29. Jenny-Avital ER. Catheter-related bloodstream infections. N Engl J Med. 2007;356(12):1267
30. Garland JS, Alex CP, Mueller CD, et al. A randomized trial comparing povidone-iodine to a chlorhexidine gluconate-impregnated dressing for prevention of central venous catheter infections in neonates. Pediatrics. 2001;107(6):1431-1436