Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients

Clinical Pharmacology and Therapeutics

Volumn 83, Issue 3, 2008, Pages 443-451

  Peeters, M Y M ^a   Bras, L J ^a   DeJongh, J ^b,c   Wesselink, R M J ^a   Aarts, L P H J ^d   Danhof, M ^c   Knibbe, C A J ^a,c  

^a ST ANTONIUS HOSPITAL   (Netherlands)

^b LAP and P Consultants BV   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PROPOFOL;

ADULT; AGED; ARTICLE; BISPECTRAL INDEX; CLINICAL ARTICLE; COMPARTMENT MODEL; CRITICALLY ILL PATIENT; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE TITRATION; FEMALE; HEART FAILURE; HUMAN; MALE; PHARMACODYNAMICS; PRIORITY JOURNAL; SCORING SYSTEM; SEDATION;

ADULT; AGED; AGED, 80 AND OVER; CRITICAL ILLNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MIDDLE AGED; MODELS, CHEMICAL; PROPOFOL; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 39449106870     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/sj.clpt.6100309     Document Type: Article

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