Viral Cross-Class Serpin Inhibits Vascular Inflammation and T Lymphocyte Fratricide; A Study in Rodent Models In Vivo and Human Cell Lines In Vitro

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Viswanathan, Kasinath ^a   Bot, Ilze ^b,c   Liu, Liying ^a,d   Dai, Erbin ^a,d   Turner, Peter C ^e   Togonu Bickersteth, Babajide ^a,d   Richardson, Jakob ^a   Davids, Jennifer A ^e   Williams, Jennifer M ^d   Bartee, Mee Y ^d,e   Chen, Hao ^d   van Berkel, Theo J C ^b,c   Biessen, Erik A L ^b,c   Moyer, Richard W ^e   Lucas, Alexandra R ^a,d,e  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b LEIDEN UNIVERSITY   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOENZYME; CASPASE; CYTOKINE RESPONSE MODIFIER A; GRANZYME B; PROTEIN SERP 2; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTERY INJURY; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DRUG INFUSION; DRUG PURIFICATION; DRUG TARGETING; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYPERLIPIDEMIA; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE; MONOCYTE; MOUSE; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; RAT; SURGICAL INJURY; VASCULITIS;

ANGIOPLASTY; ANIMALS; AORTA; APOLIPOPROTEINS E; CAROTID STENOSIS; CASPASE 1; CASPASE 8; CELL LINE; CYTOTOXICITY, IMMUNOLOGIC; GENE EXPRESSION; GRANZYMES; HUMANS; INFLAMMATION; MALE; MICE; RATS; RATS, SPRAGUE-DAWLEY; SERPINS; T-LYMPHOCYTES; VIRAL PROTEINS;

MUS; RATTUS; RODENTIA;

EID: 84866867001     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044694     Document Type: Article

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