Absence of mouse 2B4 promotes NK cell-mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis

Journal of Clinical Investigation

Volumn 120, Issue 6, 2010, Pages 1925-1938

  Waggoner, Stephen N ^a   Taniguchi, Ruth T ^b,d   Mathew, Porunelloor A ^c   Kumar, Vinay ^b   Welsh, Raymond M ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HERMES ANTIGEN; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR 2B4; PERFORIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; MOUSE; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PERSISTENT VIRUS INFECTION; PHENOTYPIC VARIATION; PRIORITY JOURNAL; SPLEEN; SPLEEN SIZE; SPLENOMEGALY; T LYMPHOCYTE ACTIVATION; VIRUS PATHOGENESIS; WILD TYPE;

ANIMALS; ANTIGENS, CD3; KILLER CELLS, NATURAL; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MICE, KNOCKOUT; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY D; PERFORIN; SPLEEN; T-LYMPHOCYTES;

EID: 77953175938     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI41264     Document Type: Article

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