메뉴 건너뛰기




Volumn 12, Issue 1, 2012, Pages 66-71

Gout as autoinflammatory disease: New mechanisms for more appropriated treatment targets

Author keywords

Autoinflammatory syndromes; Gout; Hyperuricemia; Inflammasome; Monosodium urate crystals

Indexed keywords

ALLOPURINOL; CANAKINUMAB; COLCHICINE; FEBUXOSTAT; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LESINURAD; MATRIX METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; NONSTEROID ANTIINFLAMMATORY AGENT; PEGLOTICASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RASBURICASE; REACTIVE OXYGEN METABOLITE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RILONACEPT; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANILAST; TUMOR NECROSIS FACTOR ALPHA; URATE;

EID: 84866845600     PISSN: 15689972     EISSN: 18730183     Source Type: Journal    
DOI: 10.1016/j.autrev.2012.07.024     Document Type: Review
Times cited : (80)

References (82)
  • 1
    • 25644447521 scopus 로고    scopus 로고
    • Pathogenesis of gout
    • American College of Physicians, American Physiological Society
    • Choi H.K., Mount D.B., Reginato A.M., American College of Physicians, American Physiological Society Pathogenesis of gout. Ann Intern Med 2005, 143:499-516.
    • (2005) Ann Intern Med , vol.143 , pp. 499-516
    • Choi, H.K.1    Mount, D.B.2    Reginato, A.M.3
  • 3
    • 57049083981 scopus 로고    scopus 로고
    • Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study
    • Dehghan A., Kottgen A., Yang Q., Hwang S.J., Kao W.L., Rivadeneira F., et al. Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Lancet 2008, 372:1953-1961.
    • (2008) Lancet , vol.372 , pp. 1953-1961
    • Dehghan, A.1    Kottgen, A.2    Yang, Q.3    Hwang, S.J.4    Kao, W.L.5    Rivadeneira, F.6
  • 4
    • 23644434855 scopus 로고    scopus 로고
    • A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout
    • Taniguchi A., Urano W., Yamanaka M., Yamanaka H., Hosoyamada M., Endou H., et al. A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout. Arthritis Rheum 2005, 52:2576-2577.
    • (2005) Arthritis Rheum , vol.52 , pp. 2576-2577
    • Taniguchi, A.1    Urano, W.2    Yamanaka, M.3    Yamanaka, H.4    Hosoyamada, M.5    Endou, H.6
  • 6
    • 80053497428 scopus 로고    scopus 로고
    • Prevalence of gout and hyperuricemia in the US general population
    • Zhu Y., Panya B.J., Choy H.K. Prevalence of gout and hyperuricemia in the US general population. Arthritis Rheum 2011, 63:3136-3141.
    • (2011) Arthritis Rheum , vol.63 , pp. 3136-3141
    • Zhu, Y.1    Panya, B.J.2    Choy, H.K.3
  • 7
    • 54049109693 scopus 로고    scopus 로고
    • Dietary and lifestyle changes associated with high prevalence of hyperuricemia and gout in the Shandong coastal cities of Eastern China
    • Miao Z., Li C., Chen Y., Zhao S., Wang Y., Wang Z., et al. Dietary and lifestyle changes associated with high prevalence of hyperuricemia and gout in the Shandong coastal cities of Eastern China. J Rheumatol 2008, 35:1859-1864.
    • (2008) J Rheumatol , vol.35 , pp. 1859-1864
    • Miao, Z.1    Li, C.2    Chen, Y.3    Zhao, S.4    Wang, Y.5    Wang, Z.6
  • 8
    • 65849397397 scopus 로고    scopus 로고
    • New insights into the epidemiology of gout
    • Doherty M. New insights into the epidemiology of gout. Rheumatology (Oxford) 2009, 48(Suppl. 2):ii2-ii8.
    • (2009) Rheumatology (Oxford) , vol.48 , Issue.SUPPL. 2
    • Doherty, M.1
  • 10
    • 0036636012 scopus 로고    scopus 로고
    • Contributions of paleorheumatology to understanding contemporary disease
    • Rothschild B. Contributions of paleorheumatology to understanding contemporary disease. Reumatismo 2002, 54:272-284.
    • (2002) Reumatismo , vol.54 , pp. 272-284
    • Rothschild, B.1
  • 11
    • 33745226185 scopus 로고    scopus 로고
    • A concise history of gout and hyperuricemia and their treatment
    • Nuki G., Simkin P.A. A concise history of gout and hyperuricemia and their treatment. Arthritis Res Ther 2006, 8(Suppl. 1):S1.
    • (2006) Arthritis Res Ther , vol.8 , Issue.SUPPL. 1
    • Nuki, G.1    Simkin, P.A.2
  • 12
    • 84856622252 scopus 로고    scopus 로고
    • Some historical remarks on microcrystalline arthritis (gout and chondrocalcinosis)
    • Marson P., Pasero G. Some historical remarks on microcrystalline arthritis (gout and chondrocalcinosis). Reumatismo 2012, 63:199-206.
    • (2012) Reumatismo , vol.63 , pp. 199-206
    • Marson, P.1    Pasero, G.2
  • 13
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: all we need to know about danger
    • Bianchi M.E. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 2007, 81:1-5.
    • (2007) J Leukoc Biol , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 14
    • 84862822542 scopus 로고    scopus 로고
    • Association between gout and all-cause as well as cardiovascular mortality: a systematic review
    • Lottmann K., Chen X., Schädlich P.K. Association between gout and all-cause as well as cardiovascular mortality: a systematic review. Curr Rheumatol Rep 2012, 14:195-203.
    • (2012) Curr Rheumatol Rep , vol.14 , pp. 195-203
    • Lottmann, K.1    Chen, X.2    Schädlich, P.K.3
  • 15
    • 33846998296 scopus 로고    scopus 로고
    • Prevalence of metabolic syndrome in patients with gout: the Third National Health and Nutrition Examination Survey
    • Choi H.K., Ford E.S., Li C., Curhan G. Prevalence of metabolic syndrome in patients with gout: the Third National Health and Nutrition Examination Survey. Arthritis Rheum 2007, 57:109-115.
    • (2007) Arthritis Rheum , vol.57 , pp. 109-115
    • Choi, H.K.1    Ford, E.S.2    Li, C.3    Curhan, G.4
  • 17
    • 34548511080 scopus 로고    scopus 로고
    • Pathogenetic and clinical rationale for TNF-blocking therapy in psoriatic arthritis
    • Punzi L., Podswiadek M., Sfriso P., Oliviero F., Fiocco U., Todesco S. Pathogenetic and clinical rationale for TNF-blocking therapy in psoriatic arthritis. Autoimmun Rev 2007, 6:524-528.
    • (2007) Autoimmun Rev , vol.6 , pp. 524-528
    • Punzi, L.1    Podswiadek, M.2    Sfriso, P.3    Oliviero, F.4    Fiocco, U.5    Todesco, S.6
  • 18
    • 77951800951 scopus 로고    scopus 로고
    • NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
    • Duewell P., Kono H., Katey J., Rayner K.J., Sirois C.M., Vladimer G., et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 2010, 464:1357-1361.
    • (2010) Nature , vol.464 , pp. 1357-1361
    • Duewell, P.1    Kono, H.2    Katey, J.3    Rayner, K.J.4    Sirois, C.M.5    Vladimer, G.6
  • 19
    • 84856617360 scopus 로고    scopus 로고
    • Metabolism of crystals within the joint
    • Oliviero F., Scanu A., Punzi L. Metabolism of crystals within the joint. Reumatismo 2012, 63:221-229.
    • (2012) Reumatismo , vol.63 , pp. 221-229
    • Oliviero, F.1    Scanu, A.2    Punzi, L.3
  • 20
    • 0015850877 scopus 로고
    • The synovitis of acute gouty arthritis. A light and electron microscopic study
    • Agudelo C.A., Schumacher H.R. The synovitis of acute gouty arthritis. A light and electron microscopic study. Hum Pathol 1973, 4:265-279.
    • (1973) Hum Pathol , vol.4 , pp. 265-279
    • Agudelo, C.A.1    Schumacher, H.R.2
  • 21
    • 33646556830 scopus 로고
    • The old and new concepts of acute gouty arthritis
    • Seegmiller J.E., Howell R.R. The old and new concepts of acute gouty arthritis. Arthritis Rheum 1962, 5:616-623.
    • (1962) Arthritis Rheum , vol.5 , pp. 616-623
    • Seegmiller, J.E.1    Howell, R.R.2
  • 22
    • 0014529248 scopus 로고
    • Polymorphonuclear leukocyte motility in vitro. II. Stimulatory effect of monosodium urate crystals and urate in solution; partial inhibition by colchicine and indomethacin
    • Phelps P. Polymorphonuclear leukocyte motility in vitro. II. Stimulatory effect of monosodium urate crystals and urate in solution; partial inhibition by colchicine and indomethacin. Arthritis Rheum 1969, 12:189-196.
    • (1969) Arthritis Rheum , vol.12 , pp. 189-196
    • Phelps, P.1
  • 23
    • 0031861944 scopus 로고    scopus 로고
    • Analysis of the cytokine network among tumor necrosis factor alpha, interleukin-1 beta, interleukin-8, and interleukin-1 receptor antagonist in monosodium urate crystal-induced rabbit arthritis
    • Matsukawa A., Yoshimura T., Maeda T., Takahashi T., Ohkawara S., Yoshinaga M. Analysis of the cytokine network among tumor necrosis factor alpha, interleukin-1 beta, interleukin-8, and interleukin-1 receptor antagonist in monosodium urate crystal-induced rabbit arthritis. Lab Invest 1998, 78:559-569.
    • (1998) Lab Invest , vol.78 , pp. 559-569
    • Matsukawa, A.1    Yoshimura, T.2    Maeda, T.3    Takahashi, T.4    Ohkawara, S.5    Yoshinaga, M.6
  • 24
    • 0021281375 scopus 로고
    • Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate
    • Serhan C.N., Lundberg U., Weissmann G., Samuelsson B. Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate. Prostaglandins 1984, 27:563-581.
    • (1984) Prostaglandins , vol.27 , pp. 563-581
    • Serhan, C.N.1    Lundberg, U.2    Weissmann, G.3    Samuelsson, B.4
  • 25
    • 3442885624 scopus 로고    scopus 로고
    • Monosodium urate monohydrate crystals induce the release of the proinflammatory protein S100A8/A9 from neutrophils
    • Ryckman C., Gilbert C., De Medicis R., Lussier A., Vandal K., Tessier P.A. Monosodium urate monohydrate crystals induce the release of the proinflammatory protein S100A8/A9 from neutrophils. J Leukoc Biol 2004, 76:433-440.
    • (2004) J Leukoc Biol , vol.76 , pp. 433-440
    • Ryckman, C.1    Gilbert, C.2    De Medicis, R.3    Lussier, A.4    Vandal, K.5    Tessier, P.A.6
  • 26
  • 27
    • 84857922070 scopus 로고    scopus 로고
    • Cytokine levels in human synovial fluid during the different stages of acute gout: role of transforming growth factor β1 in the resolution phase
    • Scanu A., Oliviero F., Ramonda R., Frallonardo P., Dayer J.M., Punzi L. Cytokine levels in human synovial fluid during the different stages of acute gout: role of transforming growth factor β1 in the resolution phase. Ann Rheum Dis 2012, 71:621-624.
    • (2012) Ann Rheum Dis , vol.71 , pp. 621-624
    • Scanu, A.1    Oliviero, F.2    Ramonda, R.3    Frallonardo, P.4    Dayer, J.M.5    Punzi, L.6
  • 28
    • 4344687549 scopus 로고    scopus 로고
    • Excitatory amino acids, TNF-alpha, and chemokine levels in synovial fluids of patients with active arthropathies
    • McNearney T., Baethge B.A., Cao S., Alam R., Lisse J.R., Westlund K.N. Excitatory amino acids, TNF-alpha, and chemokine levels in synovial fluids of patients with active arthropathies. Clin Exp Immunol 2004, 137:621-627.
    • (2004) Clin Exp Immunol , vol.137 , pp. 621-627
    • McNearney, T.1    Baethge, B.A.2    Cao, S.3    Alam, R.4    Lisse, J.R.5    Westlund, K.N.6
  • 29
    • 0015090568 scopus 로고
    • Sequential changes in human polymorphonuclear leukocytes after urate crystal phagocytosis
    • Schumacher H.R., Phelps P. Sequential changes in human polymorphonuclear leukocytes after urate crystal phagocytosis. Arthritis Rheum 1971, 14:513-526.
    • (1971) Arthritis Rheum , vol.14 , pp. 513-526
    • Schumacher, H.R.1    Phelps, P.2
  • 30
    • 0016267719 scopus 로고
    • Ultrastructural evidence for leakage of lysosomal contents after phagocytosis of monosodium urate crystals. A mechanism of gouty inflammation
    • Shirahama T., Cohen A.S. Ultrastructural evidence for leakage of lysosomal contents after phagocytosis of monosodium urate crystals. A mechanism of gouty inflammation. Am J Pathol 1974, 76:501-520.
    • (1974) Am J Pathol , vol.76 , pp. 501-520
    • Shirahama, T.1    Cohen, A.S.2
  • 31
    • 0016478375 scopus 로고
    • Mechanisms of lysosomal enzyme release from leukocytes. IV. Interaction of monosodium urate crystals with dogfish and human leukocytes
    • Hoffstein S., Weissmann G. Mechanisms of lysosomal enzyme release from leukocytes. IV. Interaction of monosodium urate crystals with dogfish and human leukocytes. Arthritis Rheum 1975, 18:153-165.
    • (1975) Arthritis Rheum , vol.18 , pp. 153-165
    • Hoffstein, S.1    Weissmann, G.2
  • 32
    • 0020053326 scopus 로고
    • The role of cell surface proteins in platelet stimulation by monosodium urate crystals
    • Jaques B.C., Ginsberg M.H. The role of cell surface proteins in platelet stimulation by monosodium urate crystals. Arthritis Rheum 1982, 25:508.
    • (1982) Arthritis Rheum , vol.25 , pp. 508
    • Jaques, B.C.1    Ginsberg, M.H.2
  • 33
    • 0018606411 scopus 로고
    • Polymorphonuclear leukocyte responses to monosodium urate crystals: modification by adsorbed serum proteins
    • Kozin F., Ginsberg M.H., Skosey J.L. Polymorphonuclear leukocyte responses to monosodium urate crystals: modification by adsorbed serum proteins. J Rheumatol 1979, 6:519-526.
    • (1979) J Rheumatol , vol.6 , pp. 519-526
    • Kozin, F.1    Ginsberg, M.H.2    Skosey, J.L.3
  • 34
    • 77949483766 scopus 로고    scopus 로고
    • High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals
    • Scanu A., Oliviero F., Gruaz L., Sfriso P., Pozzuoli A., Frezzato F., et al. High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals. Arthritis Res Ther 2010, 12:R23.
    • (2010) Arthritis Res Ther , vol.12
    • Scanu, A.1    Oliviero, F.2    Gruaz, L.3    Sfriso, P.4    Pozzuoli, A.5    Frezzato, F.6
  • 35
    • 0023544339 scopus 로고
    • Monosodium urate and calcium pyrophosphate crystals differentially activate the excitation-response coupling sequence of human neutrophils
    • Poubelle P.E., De Medicis R., Naccache P.H. Monosodium urate and calcium pyrophosphate crystals differentially activate the excitation-response coupling sequence of human neutrophils. Biochem Biophys Res Commun 1987, 149:649-657.
    • (1987) Biochem Biophys Res Commun , vol.149 , pp. 649-657
    • Poubelle, P.E.1    De Medicis, R.2    Naccache, P.H.3
  • 36
    • 0026017820 scopus 로고
    • Mechanism of neutrophil activation by an unopsonized inflammatory particulate. Monosodium urate crystals induce pertussis toxin-insensitive hydrolysis of phosphatidylinositol 4,5-bisphosphate
    • Onello E., Traynor-Kaplan A., Sklar L., Terkeltaub R. Mechanism of neutrophil activation by an unopsonized inflammatory particulate. Monosodium urate crystals induce pertussis toxin-insensitive hydrolysis of phosphatidylinositol 4,5-bisphosphate. J Immunol 1991, 146:4289-4294.
    • (1991) J Immunol , vol.146 , pp. 4289-4294
    • Onello, E.1    Traynor-Kaplan, A.2    Sklar, L.3    Terkeltaub, R.4
  • 37
    • 0034788345 scopus 로고    scopus 로고
    • Crystal-induced neutrophil activation. VII. Involvement of Syk in the responses to monosodium urate crystals
    • Desaulniers P., Fernandes M., Gilbert C., Bourgoin S.G., Naccache P.H. Crystal-induced neutrophil activation. VII. Involvement of Syk in the responses to monosodium urate crystals. J Leukoc Biol 2001, 70:659-668.
    • (2001) J Leukoc Biol , vol.70 , pp. 659-668
    • Desaulniers, P.1    Fernandes, M.2    Gilbert, C.3    Bourgoin, S.G.4    Naccache, P.H.5
  • 39
    • 0021070743 scopus 로고
    • Phagocytosis of sodium urate and calcium pyrophosphate crystals by leukocytes of gouty, pseudogouty and healthy donors
    • de Medicis R., Lussier A., Kahan A., Tetrault L. Phagocytosis of sodium urate and calcium pyrophosphate crystals by leukocytes of gouty, pseudogouty and healthy donors. Eur J Rheumatol Inflamm 1983, 6:143-148.
    • (1983) Eur J Rheumatol Inflamm , vol.6 , pp. 143-148
    • de Medicis, R.1    Lussier, A.2    Kahan, A.3    Tetrault, L.4
  • 40
    • 45349106084 scopus 로고    scopus 로고
    • Crystal-induced neutrophil activation: X. Proinflammatory role of the tyrosine kinase Tec
    • Popa-Nita O., Marois L., Paré G., Naccache P.H. Crystal-induced neutrophil activation: X. Proinflammatory role of the tyrosine kinase Tec. Arthritis Rheum 2008, 58:1866-1876.
    • (2008) Arthritis Rheum , vol.58 , pp. 1866-1876
    • Popa-Nita, O.1    Marois, L.2    Paré, G.3    Naccache, P.H.4
  • 41
    • 0031911975 scopus 로고    scopus 로고
    • Crystal-induced neutrophil activation VI. Involvment of FcgammaRIIIB (CD16) and CD11b in response to inflammatory microcrystals
    • Barabé F., Gilbert C., Liao N., Bourgoin S.G., Naccache P.H. Crystal-induced neutrophil activation VI. Involvment of FcgammaRIIIB (CD16) and CD11b in response to inflammatory microcrystals. FASEB J 1998, 12:209-220.
    • (1998) FASEB J , vol.12 , pp. 209-220
    • Barabé, F.1    Gilbert, C.2    Liao, N.3    Bourgoin, S.G.4    Naccache, P.H.5
  • 42
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • Shi Y., Evans J.E., Rock K.L. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 2003, 425:516-521.
    • (2003) Nature , vol.425 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3
  • 43
    • 17144371314 scopus 로고    scopus 로고
    • TLR2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation
    • Liu-Bryan R., Pritzker K., Firestein G.S., Terkeltaub R. TLR2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation. J Immunol 2005, 174:5016-5023.
    • (2005) J Immunol , vol.174 , pp. 5016-5023
    • Liu-Bryan, R.1    Pritzker, K.2    Firestein, G.S.3    Terkeltaub, R.4
  • 44
    • 33746747096 scopus 로고    scopus 로고
    • MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
    • Chen C.J., Chen C.J., Shi Y., Hearn A., Fitzgerald K., Golenbock D., et al. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest 2006, 116:2262-2271.
    • (2006) J Clin Invest , vol.116 , pp. 2262-2271
    • Chen, C.J.1    Chen, C.J.2    Shi, Y.3    Hearn, A.4    Fitzgerald, K.5    Golenbock, D.6
  • 45
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F., Pétrilli V., Mayor A., Tardivel A., Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006, 440:237-241.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Pétrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 46
    • 33750421914 scopus 로고    scopus 로고
    • Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals
    • Scott P., Ma H., Viriyakosol S., Terkeltaub R., Liu-Bryan R. Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. J Immunol 2006, 177:6370-6378.
    • (2006) J Immunol , vol.177 , pp. 6370-6378
    • Scott, P.1    Ma, H.2    Viriyakosol, S.3    Terkeltaub, R.4    Liu-Bryan, R.5
  • 47
    • 77954240379 scopus 로고    scopus 로고
    • Role of the leucine-rich repeat domain of cryopyrin/NALP3 in monosodium urate crystal-induced inflammation in mice
    • Hoffman H.M., Scott P., Mueller J.L., Misaghi A., Stevens S., Yancopoulos G.D., et al. Role of the leucine-rich repeat domain of cryopyrin/NALP3 in monosodium urate crystal-induced inflammation in mice. Arthritis Rheum 2010, 62:2170-2179.
    • (2010) Arthritis Rheum , vol.62 , pp. 2170-2179
    • Hoffman, H.M.1    Scott, P.2    Mueller, J.L.3    Misaghi, A.4    Stevens, S.5    Yancopoulos, G.D.6
  • 49
    • 70349402166 scopus 로고    scopus 로고
    • The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study
    • Terkeltaub R., Sundy J.S., Schumacher H.R., Murphy F., Bookbinder S., Biedermann S., et al. The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study. Ann Rheum Dis 2009, 68:1613-1617.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1613-1617
    • Terkeltaub, R.1    Sundy, J.S.2    Schumacher, H.R.3    Murphy, F.4    Bookbinder, S.5    Biedermann, S.6
  • 50
    • 58749083861 scopus 로고    scopus 로고
    • Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1-mediated process
    • Giamarellos-Bourboulis E.J., Mouktaroudi M., Bodar E., van der Ven J., Kullberg B.-J., Netea M.G., et al. Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1-mediated process. Ann Rheum Dis 2009, 68:273-278.
    • (2009) Ann Rheum Dis , vol.68 , pp. 273-278
    • Giamarellos-Bourboulis, E.J.1    Mouktaroudi, M.2    Bodar, E.3    van der Ven, J.4    Kullberg, B.-J.5    Netea, M.G.6
  • 51
    • 78249286865 scopus 로고    scopus 로고
    • Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis
    • Joosten L.A., Netea M.G., Mylona E., Koenders M.I., Malireddi R.K., Oosting M., et al. Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis. Arthritis Rheum 2010, 62:3237-3248.
    • (2010) Arthritis Rheum , vol.62 , pp. 3237-3248
    • Joosten, L.A.1    Netea, M.G.2    Mylona, E.3    Koenders, M.I.4    Malireddi, R.K.5    Oosting, M.6
  • 52
    • 45849102043 scopus 로고    scopus 로고
    • ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way
    • Piccini A., Carta S., Tassi S., Lasiglié D., Fossati G., Rubartelli A. ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way. Proc Natl Acad Sci U S A 2008, 105:8067-8072.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 8067-8072
    • Piccini, A.1    Carta, S.2    Tassi, S.3    Lasiglié, D.4    Fossati, G.5    Rubartelli, A.6
  • 54
    • 2542457495 scopus 로고    scopus 로고
    • Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases
    • Martinon F., Tschopp J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 2004, 117:561-574.
    • (2004) Cell , vol.117 , pp. 561-574
    • Martinon, F.1    Tschopp, J.2
  • 56
    • 78650224244 scopus 로고    scopus 로고
    • Blocking interleukin-1β in acute and chronic autoinflammatory diseases
    • Dinarello C.A. Blocking interleukin-1β in acute and chronic autoinflammatory diseases. J Intern Med 2011, 269:16-28.
    • (2011) J Intern Med , vol.269 , pp. 16-28
    • Dinarello, C.A.1
  • 57
    • 0023003715 scopus 로고
    • Apolipoprotein B mediates the capacity of low density lipoprotein to suppress neutrophil stimulation by particulates
    • Terkeltaub R., Martin J., Curtiss L.K., Ginsberg M.H. Apolipoprotein B mediates the capacity of low density lipoprotein to suppress neutrophil stimulation by particulates. J Biol Chem 1986, 261:15662-15667.
    • (1986) J Biol Chem , vol.261 , pp. 15662-15667
    • Terkeltaub, R.1    Martin, J.2    Curtiss, L.K.3    Ginsberg, M.H.4
  • 58
    • 0026033247 scopus 로고
    • Apolipoprotein (apo) E inhibits the capacity of monosodium urate crystals to stimulate neutrophils. Characterization of intraarticular apo E and demonstration of apo E binding to urate crystals in vivo
    • Terkeltaub R.A., Dyer C.A., Martin J., Curtiss L.K. Apolipoprotein (apo) E inhibits the capacity of monosodium urate crystals to stimulate neutrophils. Characterization of intraarticular apo E and demonstration of apo E binding to urate crystals in vivo. J Clin Invest 1991, 87:20-26.
    • (1991) J Clin Invest , vol.87 , pp. 20-26
    • Terkeltaub, R.A.1    Dyer, C.A.2    Martin, J.3    Curtiss, L.K.4
  • 59
    • 0024403704 scopus 로고
    • Calcium pyrophosphate and monosodium urate crystal interactions with neutrophils: effect of crystal size and lipoprotein binding to crystals
    • Burt H.M., Jackson J.K., Rowell J. Calcium pyrophosphate and monosodium urate crystal interactions with neutrophils: effect of crystal size and lipoprotein binding to crystals. J Rheumatol 1989, 16:809-817.
    • (1989) J Rheumatol , vol.16 , pp. 809-817
    • Burt, H.M.1    Jackson, J.K.2    Rowell, J.3
  • 60
    • 0037233828 scopus 로고    scopus 로고
    • Rapid induction of peroxisome proliferator-activated receptor gamma expression in human monocytes by monosodium urate monohydrate crystals
    • Akahoshi T., Namai R., Murakami Y., Watanabe M., Matsui T., Nishimura A., et al. Rapid induction of peroxisome proliferator-activated receptor gamma expression in human monocytes by monosodium urate monohydrate crystals. Arthritis Rheum 2003, 48:231-239.
    • (2003) Arthritis Rheum , vol.48 , pp. 231-239
    • Akahoshi, T.1    Namai, R.2    Murakami, Y.3    Watanabe, M.4    Matsui, T.5    Nishimura, A.6
  • 61
    • 0036744015 scopus 로고    scopus 로고
    • Antiinflammatory effect of retrovirally transfected interleukin-10 on monosodium urate monohydrate crystal-induced acute inflammation in murine air pouches
    • Murakami Y., Akahoshi T., Kawai S., Inoue M., Kitasato H. Antiinflammatory effect of retrovirally transfected interleukin-10 on monosodium urate monohydrate crystal-induced acute inflammation in murine air pouches. Arthritis Rheum 2002, 46:2504-2513.
    • (2002) Arthritis Rheum , vol.46 , pp. 2504-2513
    • Murakami, Y.1    Akahoshi, T.2    Kawai, S.3    Inoue, M.4    Kitasato, H.5
  • 62
    • 0036822278 scopus 로고    scopus 로고
    • Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis
    • Getting S.J., Christian H.C., Flower R.J., Perretti M. Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis. Arthritis Rheum 2002, 46:2765-2775.
    • (2002) Arthritis Rheum , vol.46 , pp. 2765-2775
    • Getting, S.J.1    Christian, H.C.2    Flower, R.J.3    Perretti, M.4
  • 63
    • 0036847383 scopus 로고    scopus 로고
    • Safe disposal of inflammatory monosodium urate monohydrate crystals by differentiated macrophages
    • Landis R.C., Yagnik D.R., Florey O., Philippidis P., Emons V., Mason J.C., et al. Safe disposal of inflammatory monosodium urate monohydrate crystals by differentiated macrophages. Arthritis Rheum 2002, 46:3026-3033.
    • (2002) Arthritis Rheum , vol.46 , pp. 3026-3033
    • Landis, R.C.1    Yagnik, D.R.2    Florey, O.3    Philippidis, P.4    Emons, V.5    Mason, J.C.6
  • 64
    • 3142738734 scopus 로고    scopus 로고
    • Macrophage release of transforming growth factor beta1 during resolution of monosodium urate monohydrate crystal-induced inflammation
    • Yagnik D.R., Evans B.J., Florey O., Mason J.C., Landis R.C., Haskard D.O. Macrophage release of transforming growth factor beta1 during resolution of monosodium urate monohydrate crystal-induced inflammation. Arthritis Rheum 2004, 50:2273-2280.
    • (2004) Arthritis Rheum , vol.50 , pp. 2273-2280
    • Yagnik, D.R.1    Evans, B.J.2    Florey, O.3    Mason, J.C.4    Landis, R.C.5    Haskard, D.O.6
  • 65
    • 0030015178 scopus 로고    scopus 로고
    • Inhibition and prevention of monosodium urate monohydrate crystal-induced acute inflammation in vivo by transforming growth factor beta1
    • Lioté F., Prudhommeaux F., Schiltz C., Champy R., Herbelin A., Ortiz-Bravo E., et al. Inhibition and prevention of monosodium urate monohydrate crystal-induced acute inflammation in vivo by transforming growth factor beta1. Arthritis Rheum 1996, 39:1192-1198.
    • (1996) Arthritis Rheum , vol.39 , pp. 1192-1198
    • Lioté, F.1    Prudhommeaux, F.2    Schiltz, C.3    Champy, R.4    Herbelin, A.5    Ortiz-Bravo, E.6
  • 66
    • 0037407769 scopus 로고    scopus 로고
    • Genealogy, expression, and cellular function of transforming growth factor-beta
    • Govinden R., Bhoola K.D. Genealogy, expression, and cellular function of transforming growth factor-beta. Pharmacol Ther 2003, 98:257-265.
    • (2003) Pharmacol Ther , vol.98 , pp. 257-265
    • Govinden, R.1    Bhoola, K.D.2
  • 67
    • 0024541065 scopus 로고
    • Active and latent forms of transforming growth factor beta activity in synovial effusions
    • Fava R., Olsen N., Keski-Oja J., Moses H., Pincus T. Active and latent forms of transforming growth factor beta activity in synovial effusions. J Exp Med 1989, 169:291-296.
    • (1989) J Exp Med , vol.169 , pp. 291-296
    • Fava, R.1    Olsen, N.2    Keski-Oja, J.3    Moses, H.4    Pincus, T.5
  • 68
    • 12244307898 scopus 로고    scopus 로고
    • Transforming growth factor-beta levels in synovial fluid of osteoarthritis with or without calcium pyrophosphate dihydrate crystals
    • Punzi L., Oliviero F., Ramonda R. Transforming growth factor-beta levels in synovial fluid of osteoarthritis with or without calcium pyrophosphate dihydrate crystals. J Rheumatol 2003, 30:420.
    • (2003) J Rheumatol , vol.30 , pp. 420
    • Punzi, L.1    Oliviero, F.2    Ramonda, R.3
  • 69
    • 33748608331 scopus 로고    scopus 로고
    • EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)
    • Zhang W., Doherty M., Bardin T., Pascual E., Barskova V., Conaghan P., et al. EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 2006, 65:1312-1324.
    • (2006) Ann Rheum Dis , vol.65 , pp. 1312-1324
    • Zhang, W.1    Doherty, M.2    Bardin, T.3    Pascual, E.4    Barskova, V.5    Conaghan, P.6
  • 70
    • 84856242366 scopus 로고    scopus 로고
    • Recommendations for the diagnosis and management of gout and hyperuricemia
    • Hamburger M., Baraf H.S., Adamson T.C., Basile J., Bass L., Cole B., et al. Recommendations for the diagnosis and management of gout and hyperuricemia. Postgrad Med 2011, 123(6 Suppl. 1):3-36.
    • (2011) Postgrad Med , vol.123 , Issue.6 SUPPL. 1 , pp. 3-36
    • Hamburger, M.1    Baraf, H.S.2    Adamson, T.C.3    Basile, J.4    Bass, L.5    Cole, B.6
  • 71
    • 84864867230 scopus 로고    scopus 로고
    • Patient and provider barriers to effective management of gout in general practice: A qualitative study
    • Spencer K., Carr A., Doherty M. Patient and provider barriers to effective management of gout in general practice: A qualitative study. Ann Rheum Dis 2012, 71(9):1490-1495.
    • (2012) Ann Rheum Dis , vol.71 , Issue.9 , pp. 1490-1495
    • Spencer, K.1    Carr, A.2    Doherty, M.3
  • 72
    • 77957675505 scopus 로고    scopus 로고
    • Interleukin-1 antagonism in acute gout: is targeting a single cytokine the answer?
    • Neogi T. Interleukin-1 antagonism in acute gout: is targeting a single cytokine the answer?. Arthritis Rheum 2010, 62:2845-2849.
    • (2010) Arthritis Rheum , vol.62 , pp. 2845-2849
    • Neogi, T.1
  • 73
    • 77957688721 scopus 로고    scopus 로고
    • Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: results of a multicenter, phase II, dose-ranging study
    • So A., De Meulemeester M., Pikhlak A., et al. Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: results of a multicenter, phase II, dose-ranging study. Arthritis Rheum 2010, 62:3064-3076.
    • (2010) Arthritis Rheum , vol.62 , pp. 3064-3076
    • So, A.1    De Meulemeester, M.2    Pikhlak, A.3
  • 74
    • 0029144844 scopus 로고
    • Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils
    • Cronstein B.N., Molad Y., Reibman J., Balakhane E., Levin R.I., Weissmann G. Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils. J Clin Invest 1995, 96:994-1002.
    • (1995) J Clin Invest , vol.96 , pp. 994-1002
    • Cronstein, B.N.1    Molad, Y.2    Reibman, J.3    Balakhane, E.4    Levin, R.I.5    Weissmann, G.6
  • 76
    • 35348923754 scopus 로고    scopus 로고
    • The role of interleukin-1 and the inflammasome in gout: implications for therapy
    • Pope R.M., Tschopp J. The role of interleukin-1 and the inflammasome in gout: implications for therapy. Arthritis Rheum 2007, 56:3183-3188.
    • (2007) Arthritis Rheum , vol.56 , pp. 3183-3188
    • Pope, R.M.1    Tschopp, J.2
  • 77
    • 79958836059 scopus 로고    scopus 로고
    • Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor-expressing cells: implications for its therapeutic action
    • Marques-da-Silva C., Chaves M.M., Castro N.G., Coutinho-Silva R., Guimaraes M.Z. Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor-expressing cells: implications for its therapeutic action. Br J Pharmacol 2011, 163:912-926.
    • (2011) Br J Pharmacol , vol.163 , pp. 912-926
    • Marques-da-Silva, C.1    Chaves, M.M.2    Castro, N.G.3    Coutinho-Silva, R.4    Guimaraes, M.Z.5
  • 78
    • 84873991299 scopus 로고    scopus 로고
    • Time required for disappearance of urate crystals from synovial fluid after successful hypouricaemic treatment.
    • E. Pascual, F. Sivera. Time required for disappearance of urate crystals from synovial fluid after successful hypouricaemic treatment.
    • Pascual, E.1    Sivera, F.2
  • 81
    • 84857058348 scopus 로고    scopus 로고
    • Up-to-date management of gout
    • Jordan K.M. Up-to-date management of gout. Curr Opin Rheumatol 2012, 24:145-151.
    • (2012) Curr Opin Rheumatol , vol.24 , pp. 145-151
    • Jordan, K.M.1
  • 82
    • 84859992667 scopus 로고    scopus 로고
    • Recent advances in management of gout
    • Suresh E., Das P. Recent advances in management of gout. QJM 2011, 105:407-417.
    • (2011) QJM , vol.105 , pp. 407-417
    • Suresh, E.1    Das, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.