메뉴 건너뛰기




Volumn 113, Issue 11, 2012, Pages 3466-3475

Statins modulate transcriptional activity of heme-oxygenase-1 promoter in NIH 3T3 Cells

Author keywords

C EBP; HEME OXYGENASE 1; siRNA; STATINS; USF

Indexed keywords

ANTIBODY; CCAAT ENHANCER BINDING PROTEIN BETA; CCAAT ENHANCER BINDING PROTEIN DELTA; DNA; FLUINDOSTATIN; HEME OXYGENASE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LUCIFERASE; MESSENGER RNA; MYC PROTEIN; SIMVASTATIN; UPSTREAM STIMULATORY FACTOR;

EID: 84866510855     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24223     Document Type: Article
Times cited : (19)

References (58)
  • 1
    • 0028061405 scopus 로고
    • Multiple elements within the 5' distal enhancer of the mouse heme oxygenase-1 gene mediate induction by heavy metals
    • Alam J,. 1994. Multiple elements within the 5' distal enhancer of the mouse heme oxygenase-1 gene mediate induction by heavy metals. J Biol Chem 269: 25049-25056.
    • (1994) J Biol Chem , vol.269 , pp. 25049-25056
    • Alam, J.1
  • 2
    • 0028039868 scopus 로고
    • Isolation and characterization of the mouse heme oxygenase-1 gene. Distal 5' sequences are required for induction by heme or heavy metals
    • Alam J, Cai J, Smith A,. 1994. Isolation and characterization of the mouse heme oxygenase-1 gene. Distal 5' sequences are required for induction by heme or heavy metals. J Biol Chem 269: 1001-1009.
    • (1994) J Biol Chem , vol.269 , pp. 1001-1009
    • Alam, J.1    Cai, J.2    Smith, A.3
  • 3
    • 33846924300 scopus 로고    scopus 로고
    • How many transcription factors does it take to turn on the heme oxygenase-1 gene
    • Alam J, Cook JL,. 2007. How many transcription factors does it take to turn on the heme oxygenase-1 gene ? Am J Respir Cell Mol Biol 36: 166-174.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 166-174
    • Alam, J.1    Cook, J.L.2
  • 4
    • 0026788471 scopus 로고
    • Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene
    • Alam J, Den Z,. 1992. Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene. J Biol Chem 267: 21894-21900.
    • (1992) J Biol Chem , vol.267 , pp. 21894-21900
    • Alam, J.1    Den, Z.2
  • 6
    • 0002167892 scopus 로고    scopus 로고
    • Enhanced expression of haem oxygenase-1 by nitric oxide and antiinflammatory drugs in NIH 3T3 fibroblasts
    • Alcaraz MJ, Habib A, Lebret M, Creminon C, Levy-Toledano S, Maclouf J,. 2000. Enhanced expression of haem oxygenase-1 by nitric oxide and antiinflammatory drugs in NIH 3T3 fibroblasts. Br J Pharmacol 130: 57-64.
    • (2000) Br J Pharmacol , vol.130 , pp. 57-64
    • Alcaraz, M.J.1    Habib, A.2    Lebret, M.3    Creminon, C.4    Levy-Toledano, S.5    MacLouf, J.6
  • 8
    • 0031008399 scopus 로고    scopus 로고
    • A natural classification of the basic helix-loop-helix class of transcription factors
    • Atchley WR, Fitch WM,. 1997. A natural classification of the basic helix-loop-helix class of transcription factors. Proc Natl Acad Sci USA 94: 5172-5176.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 5172-5176
    • Atchley, W.R.1    Fitch, W.M.2
  • 9
    • 56149106105 scopus 로고    scopus 로고
    • Cigarette smoke-induced expression of heme oxygenase-1 in human lung fibroblasts is regulated by intracellular glutathione
    • Baglole CJ, Sime PJ, Phipps RP,. 2008. Cigarette smoke-induced expression of heme oxygenase-1 in human lung fibroblasts is regulated by intracellular glutathione. Am J Physiol Lung Cell Mol Physiol 295: L624-L636.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295
    • Baglole, C.J.1    Sime, P.J.2    Phipps, R.P.3
  • 10
    • 73249125200 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes: Key effector cells in rheumatoid arthritis
    • Bartok B, Firestein GS,. 2010. Fibroblast-like synoviocytes: Key effector cells in rheumatoid arthritis. Immunol Rev 233: 233-255.
    • (2010) Immunol Rev , vol.233 , pp. 233-255
    • Bartok, B.1    Firestein, G.S.2
  • 11
    • 34249685010 scopus 로고    scopus 로고
    • Mevalonate pathway: A review of clinical and therapeutical implications
    • Buhaescu I, Izzedine H,. 2007. Mevalonate pathway: A review of clinical and therapeutical implications. Clin Biochem 40: 575-584.
    • (2007) Clin Biochem , vol.40 , pp. 575-584
    • Buhaescu, I.1    Izzedine, H.2
  • 12
    • 34848929072 scopus 로고    scopus 로고
    • Fluvastatin inhibits hypoxic proliferation and p38 MAPK activity in pulmonary artery fibroblasts
    • Carlin CM, Peacock AJ, Welsh DJ,. 2007. Fluvastatin inhibits hypoxic proliferation and p38 MAPK activity in pulmonary artery fibroblasts. Am J Respir Cell Mol Biol 37: 447-456.
    • (2007) Am J Respir Cell Mol Biol , vol.37 , pp. 447-456
    • Carlin, C.M.1    Peacock, A.J.2    Welsh, D.J.3
  • 13
    • 26244455871 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways
    • Chen JC, Huang KC, Lin WW,. 2006. HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways. Cell Signal 18: 32-39.
    • (2006) Cell Signal , vol.18 , pp. 32-39
    • Chen, J.C.1    Huang, K.C.2    Lin, W.W.3
  • 14
    • 84866516560 scopus 로고    scopus 로고
    • HO-1 attenuates IL-1beta-induced cPLA(2) expression via a decrease in NADPH oxidase/ROS/AP-1 activation in human rheumatoid arthritis synovial fibroblasts
    • Chi PL, Chen YW, Hsiao LD, Chen YL, Yang CM,. 2012. HO-1 attenuates IL-1beta-induced cPLA(2) expression via a decrease in NADPH oxidase/ROS/AP-1 activation in human rheumatoid arthritis synovial fibroblasts. Arthritis Rheum.
    • (2012) Arthritis Rheum
    • Chi, P.L.1    Chen, Y.W.2    Hsiao, L.D.3    Chen, Y.L.4    Yang, C.M.5
  • 15
    • 67650550793 scopus 로고    scopus 로고
    • Target gene specificity of USF-1 is directed via p38-mediated phosphorylation-dependent acetylation
    • Corre S, Primot A, Baron Y, Le Seyec J, Goding C, Galibert MD,. 2009. Target gene specificity of USF-1 is directed via p38-mediated phosphorylation-dependent acetylation. J Biol Chem 284: 18851-18862.
    • (2009) J Biol Chem , vol.284 , pp. 18851-18862
    • Corre, S.1    Primot, A.2    Baron, Y.3    Le Seyec, J.4    Goding, C.5    Galibert, M.D.6
  • 18
    • 79959702836 scopus 로고    scopus 로고
    • Protective role of heme oxygenase-1 against inflammation in atherosclerosis
    • Durante W,. 2012. Protective role of heme oxygenase-1 against inflammation in atherosclerosis. Front Biosci 17: 2372-2388.
    • (2012) Front Biosci , vol.17 , pp. 2372-2388
    • Durante, W.1
  • 19
    • 0027050007 scopus 로고
    • Myc/Max and other helix-loop-helix/leucine zipper proteins bend DNA toward the minor groove
    • Fisher DE, Parent LA, Sharp PA,. 1992. Myc/Max and other helix-loop-helix/leucine zipper proteins bend DNA toward the minor groove. Proc Natl Acad Sci USA 89: 11779-11783.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11779-11783
    • Fisher, D.E.1    Parent, L.A.2    Sharp, P.A.3
  • 22
    • 34547948422 scopus 로고    scopus 로고
    • Bach1, a heme-dependent transcription factor, reveals presence of multiple heme binding sites with distinct coordination structure
    • Hira S, Tomita T, Matsui T, Igarashi K, Ikeda-Saito M,. 2007. Bach1, a heme-dependent transcription factor, reveals presence of multiple heme binding sites with distinct coordination structure. IUBMB Life 59: 542-551.
    • (2007) IUBMB Life , vol.59 , pp. 542-551
    • Hira, S.1    Tomita, T.2    Matsui, T.3    Igarashi, K.4    Ikeda-Saito, M.5
  • 23
    • 7444225158 scopus 로고    scopus 로고
    • Upstream stimulatory factors, USF1 and USF2, bind to the human haem oxygenase-1 proximal promoter in vivo and regulate its transcription
    • Hock TD, Nick HS, Agarwal A,. 2004. Upstream stimulatory factors, USF1 and USF2, bind to the human haem oxygenase-1 proximal promoter in vivo and regulate its transcription. Biochem J 383: 209-218.
    • (2004) Biochem J , vol.383 , pp. 209-218
    • Hock, T.D.1    Nick, H.S.2    Agarwal, A.3
  • 24
    • 33644550593 scopus 로고    scopus 로고
    • Statins prevent NF-kappaB transactivation independently of the IKK-pathway in human endothelial cells
    • Holschermann H, Schuster D, Parviz B, Haberbosch W, Tillmanns H, Muth H,. 2006. Statins prevent NF-kappaB transactivation independently of the IKK-pathway in human endothelial cells. Atherosclerosis 185: 240-245.
    • (2006) Atherosclerosis , vol.185 , pp. 240-245
    • Holschermann, H.1    Schuster, D.2    Parviz, B.3    Haberbosch, W.4    Tillmanns, H.5    Muth, H.6
  • 25
    • 83555165880 scopus 로고    scopus 로고
    • Simvastatin protects osteoblast against H2O2-induced oxidative damage via inhibiting the upregulation of Nox4
    • Huang W, Shang WL, Li DH, Wu WW, Hou SX,. 2012. Simvastatin protects osteoblast against H2O2-induced oxidative damage via inhibiting the upregulation of Nox4. Mol Cell Biochem 360: 71-77.
    • (2012) Mol Cell Biochem , vol.360 , pp. 71-77
    • Huang, W.1    Shang, W.L.2    Li, D.H.3    Wu, W.W.4    Hou, S.X.5
  • 26
    • 33644643191 scopus 로고    scopus 로고
    • The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation
    • Igarashi K, Sun J,. 2006. The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation. Antioxid Redox Signal 8: 107-118.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 107-118
    • Igarashi, K.1    Sun, J.2
  • 28
    • 54749083116 scopus 로고    scopus 로고
    • Heme oxygenase-1 deficiency promotes epithelial-mesenchymal transition and renal fibrosis
    • Kie JH, Kapturczak MH, Traylor A, Agarwal A, Hill-Kapturczak N,. 2008. Heme oxygenase-1 deficiency promotes epithelial-mesenchymal transition and renal fibrosis. J Am Soc Nephrol 19: 1681-1691.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1681-1691
    • Kie, J.H.1    Kapturczak, M.H.2    Traylor, A.3    Agarwal, A.4    Hill-Kapturczak, N.5
  • 30
    • 0034730812 scopus 로고    scopus 로고
    • Targeting Rho in cardiovascular disease
    • Laufs U, Liao JK,. 2000. Targeting Rho in cardiovascular disease. Circ Res 87: 526-528.
    • (2000) Circ Res , vol.87 , pp. 526-528
    • Laufs, U.1    Liao, J.K.2
  • 31
    • 0031041377 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia
    • Lee PJ, Jiang BH, Chin BY, Iyer NV, Alam J, Semenza GL, Choi AM,. 1997. Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J Biol Chem 272: 5375-5381.
    • (1997) J Biol Chem , vol.272 , pp. 5375-5381
    • Lee, P.J.1    Jiang, B.H.2    Chin, B.Y.3    Iyer, N.V.4    Alam, J.5    Semenza, G.L.6    Choi, A.M.7
  • 32
    • 4444369432 scopus 로고    scopus 로고
    • Simvastatin induces heme oxygenase-1: A novel mechanism of vessel protection
    • Lee TS, Chang CC, Zhu Y, Shyy JY,. 2004. Simvastatin induces heme oxygenase-1: A novel mechanism of vessel protection. Circulation 110: 1296-1302.
    • (2004) Circulation , vol.110 , pp. 1296-1302
    • Lee, T.S.1    Chang, C.C.2    Zhu, Y.3    Shyy, J.Y.4
  • 33
    • 0036127426 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
    • Lee TS, Chau LY,. 2002. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat Med 8: 240-246.
    • (2002) Nat Med , vol.8 , pp. 240-246
    • Lee, T.S.1    Chau, L.Y.2
  • 35
    • 29444438428 scopus 로고    scopus 로고
    • Clinical implications for statin pleiotropy
    • Liao JK,. 2005. Clinical implications for statin pleiotropy. Curr Opin Lipidol 16: 624-629.
    • (2005) Curr Opin Lipidol , vol.16 , pp. 624-629
    • Liao, J.K.1
  • 37
    • 34250195017 scopus 로고    scopus 로고
    • Rosuvastatin reduces interleukin-6-induced expression of C-reactive protein in human hepatocytes in a STAT3- and C/EBP-dependent fashion
    • Mayer C, Gruber HJ, Landl EM, Pailer S, Scharnagl H, Truschnig-Wilders M, Marz W,. 2007. Rosuvastatin reduces interleukin-6-induced expression of C-reactive protein in human hepatocytes in a STAT3- and C/EBP-dependent fashion. Int J Clin Pharmacol Ther 45: 319-327.
    • (2007) Int J Clin Pharmacol Ther , vol.45 , pp. 319-327
    • Mayer, C.1    Gruber, H.J.2    Landl, E.M.3    Pailer, S.4    Scharnagl, H.5    Truschnig-Wilders, M.6    Marz, W.7
  • 38
    • 79952409755 scopus 로고    scopus 로고
    • Heme oxygenase-1: A novel therapeutic target for gastrointestinal diseases
    • Naito Y, Takagi T, Uchiyama K, Yoshikawa T,. 2011. Heme oxygenase-1: A novel therapeutic target for gastrointestinal diseases. J Clin Biochem Nutr 48: 126-133.
    • (2011) J Clin Biochem Nutr , vol.48 , pp. 126-133
    • Naito, Y.1    Takagi, T.2    Uchiyama, K.3    Yoshikawa, T.4
  • 39
    • 78049442406 scopus 로고    scopus 로고
    • Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential
    • Paine A, Eiz-Vesper B, Blasczyk R, Immenschuh S,. 2010. Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential. Biochem Pharmacol 80: 1895-1903.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1895-1903
    • Paine, A.1    Eiz-Vesper, B.2    Blasczyk, R.3    Immenschuh, S.4
  • 41
    • 34548429119 scopus 로고    scopus 로고
    • Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta-cells
    • Pugazhenthi S, Akhov L, Selvaraj G, Wang M, Alam J,. 2007. Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta-cells. Am J Physiol Endocrinol Metab 293: E645-E655.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Pugazhenthi, S.1    Akhov, L.2    Selvaraj, G.3    Wang, M.4    Alam, J.5
  • 42
    • 84655169827 scopus 로고    scopus 로고
    • The role of Bach1 in ultraviolet A-mediated human heme oxygenase 1 regulation in human skin fibroblasts
    • Raval CM, Zhong JL, Mitchell SA, Tyrrell RM,. 2012. The role of Bach1 in ultraviolet A-mediated human heme oxygenase 1 regulation in human skin fibroblasts. Free Radic Biol Med 52: 227-236.
    • (2012) Free Radic Biol Med , vol.52 , pp. 227-236
    • Raval, C.M.1    Zhong, J.L.2    Mitchell, S.A.3    Tyrrell, R.M.4
  • 43
    • 33644694919 scopus 로고    scopus 로고
    • Rho GTPases, statins, and nitric oxide
    • Rikitake Y, Liao JK,. 2005. Rho GTPases, statins, and nitric oxide. Circ Res 97: 1232-1235.
    • (2005) Circ Res , vol.97 , pp. 1232-1235
    • Rikitake, Y.1    Liao, J.K.2
  • 44
    • 33645945014 scopus 로고    scopus 로고
    • Heme oxygenase-1/carbon monoxide: From basic science to therapeutic applications
    • Ryter SW, Alam J, Choi AM,. 2006. Heme oxygenase-1/carbon monoxide: From basic science to therapeutic applications. Physiol Rev 86: 583-650.
    • (2006) Physiol Rev , vol.86 , pp. 583-650
    • Ryter, S.W.1    Alam, J.2    Choi, A.M.3
  • 46
    • 2642549921 scopus 로고    scopus 로고
    • Liver-enriched transcription factors in liver function and development. Part II: The C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation
    • Schrem H, Klempnauer J, Borlak J,. 2004. Liver-enriched transcription factors in liver function and development. Part II: The C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation. Pharmacol Rev 56: 291-330.
    • (2004) Pharmacol Rev , vol.56 , pp. 291-330
    • Schrem, H.1    Klempnauer, J.2    Borlak, J.3
  • 47
    • 17444408968 scopus 로고    scopus 로고
    • Protein farnesylation: Implications for normal physiology, malignant transformation, and cancer therapy
    • Sebti SM,. 2005. Protein farnesylation: Implications for normal physiology, malignant transformation, and cancer therapy. Cancer Cell 7: 297-300.
    • (2005) Cancer Cell , vol.7 , pp. 297-300
    • Sebti, S.M.1
  • 49
    • 84855990785 scopus 로고    scopus 로고
    • Angiotensin-II and rosuvastatin influence matrix remodeling in human mesangial cells via metalloproteinase modulation
    • Solini A, Rossi C, Santini E, Madec S, Salvati A, Ferrannini E,. 2011. Angiotensin-II and rosuvastatin influence matrix remodeling in human mesangial cells via metalloproteinase modulation. J Hypertens 29: 1930-1939.
    • (2011) J Hypertens , vol.29 , pp. 1930-1939
    • Solini, A.1    Rossi, C.2    Santini, E.3    Madec, S.4    Salvati, A.5    Ferrannini, E.6
  • 50
    • 54249153411 scopus 로고    scopus 로고
    • Simvastatin suppresses LPS-induced MMP-1 expression in U937 mononuclear cells by inhibiting protein isoprenylation-mediated ERK activation
    • Sundararaj KP, Samuvel DJ, Li Y, Nareika A, Slate EH, Sanders JJ, Lopes-Virella MF, Huang Y,. 2008. Simvastatin suppresses LPS-induced MMP-1 expression in U937 mononuclear cells by inhibiting protein isoprenylation- mediated ERK activation. J Leukoc Biol 84: 1120-1129.
    • (2008) J Leukoc Biol , vol.84 , pp. 1120-1129
    • Sundararaj, K.P.1    Samuvel, D.J.2    Li, Y.3    Nareika, A.4    Slate, E.H.5    Sanders, J.J.6    Lopes-Virella, M.F.7    Huang, Y.8
  • 51
    • 0141733235 scopus 로고    scopus 로고
    • The IGF2 receptor is a USF2-specific target in nontumorigenic mammary epithelial cells but not in breast cancer cells
    • Szentirmay MN, Yang HX, Pawar SA, Vinson C, Sawadogo M,. 2003. The IGF2 receptor is a USF2-specific target in nontumorigenic mammary epithelial cells but not in breast cancer cells. J Biol Chem 278: 37231-37240.
    • (2003) J Biol Chem , vol.278 , pp. 37231-37240
    • Szentirmay, M.N.1    Yang, H.X.2    Pawar, S.A.3    Vinson, C.4    Sawadogo, M.5
  • 52
    • 79952073585 scopus 로고    scopus 로고
    • The CCAAT/enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation
    • Tsukada J, Yoshida Y, Kominato Y, Auron PE,. 2011. The CCAAT/enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation. Cytokine 54: 6-19.
    • (2011) Cytokine , vol.54 , pp. 6-19
    • Tsukada, J.1    Yoshida, Y.2    Kominato, Y.3    Auron, P.E.4
  • 54
    • 4544242791 scopus 로고    scopus 로고
    • Solar ultraviolet A radiation: An oxidizing skin carcinogen that activates heme oxygenase-1
    • Tyrrell RM,. 2004. Solar ultraviolet A radiation: An oxidizing skin carcinogen that activates heme oxygenase-1. Antioxid Redox Signal 6: 835-840.
    • (2004) Antioxid Redox Signal , vol.6 , pp. 835-840
    • Tyrrell, R.M.1
  • 55
    • 0345167189 scopus 로고    scopus 로고
    • Beneficial effects of heme oxygenase-1 up-regulation in the development of experimental inflammation induced by zymosan
    • Vicente AM, Guillen MI, Habib A, Alcaraz MJ,. 2003. Beneficial effects of heme oxygenase-1 up-regulation in the development of experimental inflammation induced by zymosan. J Pharmacol Exp Ther 307: 1030-1037.
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 1030-1037
    • Vicente, A.M.1    Guillen, M.I.2    Habib, A.3    Alcaraz, M.J.4
  • 58
    • 79952455313 scopus 로고    scopus 로고
    • Rho-associated coiled-coil-forming kinases (ROCKs): Potential targets for the treatment of atherosclerosis and vascular disease
    • Zhou Q, Gensch C, Liao JK,. 2011. Rho-associated coiled-coil-forming kinases (ROCKs): Potential targets for the treatment of atherosclerosis and vascular disease. Trends Pharmacol Sci 32: 167-173.
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 167-173
    • Zhou, Q.1    Gensch, C.2    Liao, J.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.