Simvastatin protects osteoblast against H 2O 2-induced oxidative damage via inhibiting the upregulation of Nox4

Molecular and Cellular Biochemistry

Volumn 360, Issue 1-2, 2012, Pages 71-77

  Huang, Wei ^a   Shang, Wei Lin ^a   Li, De Hao ^a   Wu, Wen Wen ^a   Hou, Shu Xun ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Hydrogen peroxide; NADPH oxidase; Nox4; Simvastatin

Indexed keywords

ALKALINE PHOSPHATASE; FARNESYL DIPHOSPHATE; GERANYLGERANYL PYROPHOSPHATE; HYDROGEN PEROXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SIMVASTATIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DAMAGE; CELL DIFFERENTIATION; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; MOUSE; NONHUMAN; OSTEOBLAST; OXIDATIVE STRESS; UPREGULATION;

3T3 CELLS; ALKALINE PHOSPHATASE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; CYTOPROTECTION; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HYDROGEN PEROXIDE; MALONDIALDEHYDE; MICE; NADPH OXIDASE; OSTEOBLASTS; OXIDATIVE STRESS; RNA INTERFERENCE; SIMVASTATIN; UP-REGULATION;

MURINAE;

EID: 83555165880     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-1045-5     Document Type: Article

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