-
1
-
-
33847035824
-
Phosphorylation of HuR by Chk2 regulates SIRT1 expression
-
Abdelmohsen K., Pullmann R., Lal A., Kim H.H., Galban S., Yang X., Blethrow J.D., Walker M., Shubert J., Gillespie D.A., Furneaux H., Gorospe M. Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol. Cell 2007, 25:543-557.
-
(2007)
Mol. Cell
, vol.25
, pp. 543-557
-
-
Abdelmohsen, K.1
Pullmann, R.2
Lal, A.3
Kim, H.H.4
Galban, S.5
Yang, X.6
Blethrow, J.D.7
Walker, M.8
Shubert, J.9
Gillespie, D.A.10
Furneaux, H.11
Gorospe, M.12
-
2
-
-
40149096226
-
Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence
-
Abdelmohsen K., Kuwano Y., Kim H.H., Gorospe M. Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol. Chem. 2008, 389:243-255.
-
(2008)
Biol. Chem.
, vol.389
, pp. 243-255
-
-
Abdelmohsen, K.1
Kuwano, Y.2
Kim, H.H.3
Gorospe, M.4
-
3
-
-
79952759375
-
Posttranscriptional regulation of cancer traits by HuR
-
Abdelmohsen K., Gorospe M. Posttranscriptional regulation of cancer traits by HuR. Wiley Interdiscip. Rev. RNA 2010, 1:214-229.
-
(2010)
Wiley Interdiscip. Rev. RNA
, vol.1
, pp. 214-229
-
-
Abdelmohsen, K.1
Gorospe, M.2
-
4
-
-
16844362149
-
Post-transcriptional regulation in cancer
-
Audic Y., Hartley R.S. Post-transcriptional regulation in cancer. Biol. Cell 2004, 96:479-498.
-
(2004)
Biol. Cell
, vol.96
, pp. 479-498
-
-
Audic, Y.1
Hartley, R.S.2
-
5
-
-
0036727326
-
Messenger RNA decay during aging and development
-
Brewer G. Messenger RNA decay during aging and development. Ageing Res. Rev. 2002, 1:607-625.
-
(2002)
Ageing Res. Rev.
, vol.1
, pp. 607-625
-
-
Brewer, G.1
-
6
-
-
0034028836
-
Tumor suppressors and oncogenes in cellular senescence
-
Bringgold F., Serrano M. Tumor suppressors and oncogenes in cellular senescence. Exp. Gerontol. 2000, 35:179-329.
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 179-329
-
-
Bringgold, F.1
Serrano, M.2
-
7
-
-
77956382385
-
Sirtuin 1 regulation of developmental genes during differentiation of stem cells
-
Calvanese V., Lara E., Suárez-Alvarez B., Abu Dawud R., Vázquez-Chantada M., Martínez-Chantar M.L., Embade N., López-Nieva P., Horrillo A., Hmadcha A., Soria B., Piazzolla D., Herranz D., Serrano M., Mato J.M., Andrews P.W., López-Larrea C., Esteller M., Fraga M.F. Sirtuin 1 regulation of developmental genes during differentiation of stem cells. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:13736-13741.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 13736-13741
-
-
Calvanese, V.1
Lara, E.2
Suárez-Alvarez, B.3
Abu Dawud, R.4
Vázquez-Chantada, M.5
Martínez-Chantar, M.L.6
Embade, N.7
López-Nieva, P.8
Horrillo, A.9
Hmadcha, A.10
Soria, B.11
Piazzolla, D.12
Herranz, D.13
Serrano, M.14
Mato, J.M.15
Andrews, P.W.16
López-Larrea, C.17
Esteller, M.18
Fraga, M.F.19
-
8
-
-
0035500487
-
Cellular senescence as a tumor-suppressor mechanism
-
Campici J. Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol. 2001, 11:S27-S31.
-
(2001)
Trends Cell Biol.
, vol.11
-
-
Campici, J.1
-
9
-
-
77955302347
-
INK4 mRNA decay
-
INK4 mRNA decay. Mol. Cell. Biol. 2010, 30:3875-3886.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 3875-3886
-
-
Chang, N.1
Yi, J.2
Guo, G.3
Liu, X.4
Shang, Y.5
Tong, T.6
Cui, Q.7
Zhan, M.8
Gorospe, M.9
Wang, W.10
-
10
-
-
67749132423
-
Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
-
Chi S.W., Zang J.B., Mele A., Darnell R.B. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 2009, 460:479-486.
-
(2009)
Nature
, vol.460
, pp. 479-486
-
-
Chi, S.W.1
Zang, J.B.2
Mele, A.3
Darnell, R.B.4
-
11
-
-
78751504841
-
Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment
-
Clement S.L., Scheckel C., Stoecklin G., Lykke-Andersen J. Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment. Mol. Cell. Biol. 2011, 31:256-266.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 256-266
-
-
Clement, S.L.1
Scheckel, C.2
Stoecklin, G.3
Lykke-Andersen, J.4
-
12
-
-
1642332899
-
MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding
-
Chrestensen C.A., Schroeder M.J., Shabanowitz J., Hunt D.F., Pelo J.W., Worthington M.T., Sturgill T.W. MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding. J. Biol. Chem. 2004, 279:10176-10184.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 10176-10184
-
-
Chrestensen, C.A.1
Schroeder, M.J.2
Shabanowitz, J.3
Hunt, D.F.4
Pelo, J.W.5
Worthington, M.T.6
Sturgill, T.W.7
-
13
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen H.Y., Miller C., Bitterman K.J., Wall N.R., Hekking B., Kessler B., Howitz K.T., Gorospe M., de Cabo R., Sinclair D.A. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004, 305:390-392.
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
de Cabo, R.9
Sinclair, D.A.10
-
14
-
-
0021781850
-
Cellular senescence: factors modulating cell proliferation in vitro
-
Cristofalo V.J., Phillips P.D., Brooks K.M. Cellular senescence: factors modulating cell proliferation in vitro. Basic Life Sci. 1985, 35:241-253.
-
(1985)
Basic Life Sci.
, vol.35
, pp. 241-253
-
-
Cristofalo, V.J.1
Phillips, P.D.2
Brooks, K.M.3
-
15
-
-
0026690335
-
Changes in gene expression during senescence in culture
-
Cristofalo V.J., Pignolo R.J., Cianciarulo F.L., DiPaolo B.R., Rotenberg M.O. Changes in gene expression during senescence in culture. Exp. Gerontol. 1992, 27:429-432.
-
(1992)
Exp. Gerontol.
, vol.27
, pp. 429-432
-
-
Cristofalo, V.J.1
Pignolo, R.J.2
Cianciarulo, F.L.3
DiPaolo, B.R.4
Rotenberg, M.O.5
-
16
-
-
0032470459
-
Age-dependent modifications of gene expression in human fibroblasts
-
Cristofalo V.J., Volker C., Francis M.K., Tresini M. Age-dependent modifications of gene expression in human fibroblasts. Crit. Rev. Eukaryot. Gene Expr. 1998, 8:43-80.
-
(1998)
Crit. Rev. Eukaryot. Gene Expr.
, vol.8
, pp. 43-80
-
-
Cristofalo, V.J.1
Volker, C.2
Francis, M.K.3
Tresini, M.4
-
17
-
-
34250362729
-
Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2
-
Doller A., Huwiler A., Müller R., Radeke H.H., Pfeilschifter J., Eberhardt W. Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2. Mol. Biol. Cell 2007, 18:2137-2148.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 2137-2148
-
-
Doller, A.1
Huwiler, A.2
Müller, R.3
Radeke, H.H.4
Pfeilschifter, J.5
Eberhardt, W.6
-
18
-
-
55049088775
-
Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR
-
Doller A., Pfeilschifter J., Eberhardt W. Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR. Cell. Signal. 2008, 20:2165-2173.
-
(2008)
Cell. Signal.
, vol.20
, pp. 2165-2173
-
-
Doller, A.1
Pfeilschifter, J.2
Eberhardt, W.3
-
19
-
-
77749334696
-
Tandem phosphorylation of serines 221 and 318 by protein kinase Cdelta coordinates mRNA binding and nucleocytoplasmic shuttling of HuR
-
Doller A., Schlepckow K., Schwalbe H., Pfeilschifter J., Eberhardt W. Tandem phosphorylation of serines 221 and 318 by protein kinase Cdelta coordinates mRNA binding and nucleocytoplasmic shuttling of HuR. Mol. Cell. Biol. 2010, 30:1397-1410.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1397-1410
-
-
Doller, A.1
Schlepckow, K.2
Schwalbe, H.3
Pfeilschifter, J.4
Eberhardt, W.5
-
20
-
-
0027959502
-
Characterization of cDNAs encoding the murine A+U-rich RNA-binding protein AUF1
-
Ehrenman K., Long L., Wagner B.J., Brewer G. Characterization of cDNAs encoding the murine A+U-rich RNA-binding protein AUF1. Gene 1994, 149:315-319.
-
(1994)
Gene
, vol.149
, pp. 315-319
-
-
Ehrenman, K.1
Long, L.2
Wagner, B.J.3
Brewer, G.4
-
21
-
-
0032431026
-
HNS, a nuclear-cytoplasmic shuttling sequence in HuR
-
Fan X.C., Steitz J.A. HNS, a nuclear-cytoplasmic shuttling sequence in HuR. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:15293-15298.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 15293-15298
-
-
Fan, X.C.1
Steitz, J.A.2
-
22
-
-
33750614472
-
A liaison dangereuse between AUF1/hnRNPD and the oncogenic tyrosine kinase NPM-ALK
-
Fawal M., Armstrong F., Ollier S., Dupont H., Touriol C/, Monsarrat B., Delsol G., Payrastre B., Morello D. A liaison dangereuse between AUF1/hnRNPD and the oncogenic tyrosine kinase NPM-ALK. Blood 2006, 108:2780-2788.
-
(2006)
Blood
, vol.108
, pp. 2780-2788
-
-
Fawal, M.1
Armstrong, F.2
Ollier, S.3
Dupont, H.4
Touriol, C.5
Monsarrat, B.6
Delsol, G.7
Payrastre, B.8
Morello, D.9
-
23
-
-
0842321787
-
Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase
-
Frasca D., Van der Put E., Riley R.L., Blomberg B.B. Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase. J. Immunol. 2004, 172:2155-2162.
-
(2004)
J. Immunol.
, vol.172
, pp. 2155-2162
-
-
Frasca, D.1
Van der Put, E.2
Riley, R.L.3
Blomberg, B.B.4
-
24
-
-
34548754592
-
Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA
-
Frasca D., Landin A.M., Alvarez J.P., Blackshear P.J., Riley R.L., Blomberg B.B. Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA. J. Immunol. 2007, 179:918-927.
-
(2007)
J. Immunol.
, vol.179
, pp. 918-927
-
-
Frasca, D.1
Landin, A.M.2
Alvarez, J.P.3
Blackshear, P.J.4
Riley, R.L.5
Blomberg, B.B.6
-
25
-
-
77953050555
-
Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability
-
Frasca D., Romero M., Landin A.M., Diaz A., Riley R.L., Blomberg B.B. Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability. Mech. Ageing Dev. 2010, 131:306-314.
-
(2010)
Mech. Ageing Dev.
, vol.131
, pp. 306-314
-
-
Frasca, D.1
Romero, M.2
Landin, A.M.3
Diaz, A.4
Riley, R.L.5
Blomberg, B.B.6
-
26
-
-
33646552414
-
The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors
-
Frye M., Watt F.M. The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors. Curr. Biol. 2006, 16:971-981.
-
(2006)
Curr. Biol.
, vol.16
, pp. 971-981
-
-
Frye, M.1
Watt, F.M.2
-
27
-
-
0032567975
-
Telomeres and senescence: the history, the experiment, the future
-
Greider C.W. Telomeres and senescence: the history, the experiment, the future. Curr. Biol. 1998, 8:R178-R181.
-
(1998)
Curr. Biol.
, vol.8
-
-
Greider, C.W.1
-
29
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L., Moorhead P.S. The serial cultivation of human diploid cell strains. Exp. Cell Res. 1961, 25:585-621.
-
(1961)
Exp. Cell Res.
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
30
-
-
45849137875
-
SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts
-
Huang J., Gan Q., Han L., Li J., Zhang H., Sun Y., Zhang Z., Tong T. SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts. PLoS ONE 2008, 3:1710.
-
(2008)
PLoS ONE
, vol.3
, pp. 1710
-
-
Huang, J.1
Gan, Q.2
Han, L.3
Li, J.4
Zhang, H.5
Sun, Y.6
Zhang, Z.7
Tong, T.8
-
31
-
-
1542320700
-
Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate
-
Iakova P., Wang G.L., Timchenko L., Michalak M., Pereira-Smith O.M., Smith J.R., Timchenko N.A. Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate. EMBO J. 2004, 23:406-417.
-
(2004)
EMBO J.
, vol.23
, pp. 406-417
-
-
Iakova, P.1
Wang, G.L.2
Timchenko, L.3
Michalak, M.4
Pereira-Smith, O.M.5
Smith, J.R.6
Timchenko, N.A.7
-
32
-
-
0032104625
-
The making and breaking of senescence: changes of gene expression during cellular aging and immortalization
-
Jansen-Durr P. The making and breaking of senescence: changes of gene expression during cellular aging and immortalization. Exp. Gerontol. 1998, 33:291-301.
-
(1998)
Exp. Gerontol.
, vol.33
, pp. 291-301
-
-
Jansen-Durr, P.1
-
33
-
-
68449097694
-
GSK3beta-cyclin D3-CUGBP1-eIF2 pathway in aging and in myotonic dystrophy
-
Jin J., Wang G.L., Salisbury E., Timchenko L., Timchenko N.A. GSK3beta-cyclin D3-CUGBP1-eIF2 pathway in aging and in myotonic dystrophy. Cell Cycle 2009, 8:2356-2359.
-
(2009)
Cell Cycle
, vol.8
, pp. 2356-2359
-
-
Jin, J.1
Wang, G.L.2
Salisbury, E.3
Timchenko, L.4
Timchenko, N.A.5
-
34
-
-
34250735674
-
RNA regulons: coordination of post-transcriptional events
-
Keene J.D. RNA regulons: coordination of post-transcriptional events. Nat. Rev. Genet. 2007, 8:533-543.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 533-543
-
-
Keene, J.D.1
-
35
-
-
0035902108
-
Genome maitenance mechanisms for preventing cancer
-
Hoeijmakers J.H.J. Genome maitenance mechanisms for preventing cancer. Nature 2001, 411:366-374.
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.J.1
-
36
-
-
68149165414
-
HuR recruits let-7/RISC to repress c-Myc expression
-
Kim H.H., Kuwano Y., Srikantan S., Lee E.K., Martindale J.L., Gorospe M. HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev. 2009, 23:1743-1748.
-
(2009)
Genes Dev.
, vol.23
, pp. 1743-1748
-
-
Kim, H.H.1
Kuwano, Y.2
Srikantan, S.3
Lee, E.K.4
Martindale, J.L.5
Gorospe, M.6
-
37
-
-
46249130717
-
Nuclear HuR accumulation through phosphorylation by Cdk1
-
Kim H.H., Abdelmohsen K., Lal A., Pullmann R., Yang X., Galban S., Srikantan S., Martindale J.L., Blethrow J., Shokat K.M., Gorospe M. Nuclear HuR accumulation through phosphorylation by Cdk1. Genes Dev. 2008, 22:1804-1815.
-
(2008)
Genes Dev.
, vol.22
, pp. 1804-1815
-
-
Kim, H.H.1
Abdelmohsen, K.2
Lal, A.3
Pullmann, R.4
Yang, X.5
Galban, S.6
Srikantan, S.7
Martindale, J.L.8
Blethrow, J.9
Shokat, K.M.10
Gorospe, M.11
-
38
-
-
67449084504
-
Emerging roles of RNA and RNA-binding protein network in cancer cells
-
Kim M.Y., Hur J., Jeong S. Emerging roles of RNA and RNA-binding protein network in cancer cells. BMB Rep. 2009, 42:125-130.
-
(2009)
BMB Rep.
, vol.42
, pp. 125-130
-
-
Kim, M.Y.1
Hur, J.2
Jeong, S.3
-
39
-
-
0036894711
-
ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR
-
Kullmann M., Göpfert U., Siewe B., Hengst L. ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR. Genes Dev. 2002, 16:3087-3099.
-
(2002)
Genes Dev.
, vol.16
, pp. 3087-3099
-
-
Kullmann, M.1
Göpfert, U.2
Siewe, B.3
Hengst, L.4
-
40
-
-
34948834723
-
Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation
-
Kuyumcu-Martinez N.M., Wang G.S., Cooper T.A. Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation. Mol. Cell 2007, 28:68-78.
-
(2007)
Mol. Cell
, vol.28
, pp. 68-78
-
-
Kuyumcu-Martinez, N.M.1
Wang, G.S.2
Cooper, T.A.3
-
41
-
-
4143122397
-
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
-
Lal A., Mazan-Mamczarz K., Kawai T., Yang X., Martindale J.L., Gorospe M. Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J. 2004, 23:3092-3102.
-
(2004)
EMBO J.
, vol.23
, pp. 3092-3102
-
-
Lal, A.1
Mazan-Mamczarz, K.2
Kawai, T.3
Yang, X.4
Martindale, J.L.5
Gorospe, M.6
-
42
-
-
79959854185
-
Transcriptional regulation of cellular senescence
-
Lanigan F., Geraghty J.G., Bracken A.P. Transcriptional regulation of cellular senescence. Oncogene 2011, 30:2901-2911.
-
(2011)
Oncogene
, vol.30
, pp. 2901-2911
-
-
Lanigan, F.1
Geraghty, J.G.2
Bracken, A.P.3
-
43
-
-
79958760883
-
Casein kinase 2 regulates the mRNA-destabilizing activity of tristetraprolin
-
Lee W.H., Lee H.H., Vo M.T., Kim H.J., Ko M.S., Im Y.C., Min Y.J., Lee B.J., Cho W.J., Park J.W. Casein kinase 2 regulates the mRNA-destabilizing activity of tristetraprolin. J. Biol. Chem. 2011, 286:21577-21587.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 21577-21587
-
-
Lee, W.H.1
Lee, H.H.2
Vo, M.T.3
Kim, H.J.4
Ko, M.S.5
Im, Y.C.6
Min, Y.J.7
Lee, B.J.8
Cho, W.J.9
Park, J.W.10
-
44
-
-
0348150716
-
Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1 Coactivator-associated argininemethyltransferase
-
Li H., Park S., Kilburn B., Jelinek M.A., Henschen-Edman A., Aswad D.W., Stallcup M.R., Laird-Offringa I.A. Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1 Coactivator-associated argininemethyltransferase. J. Biol. Chem. 2002, 277:44623-44630.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44623-44630
-
-
Li, H.1
Park, S.2
Kilburn, B.3
Jelinek, M.A.4
Henschen-Edman, A.5
Aswad, D.W.6
Stallcup, M.R.7
Laird-Offringa, I.A.8
-
45
-
-
34249875986
-
Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation
-
Liao B., Hu Y., Brewer G. Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation. Nat. Struct. Mol. Biol. 2007, 14:511-518.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 511-518
-
-
Liao, B.1
Hu, Y.2
Brewer, G.3
-
46
-
-
53549091320
-
CSIG regulates PTEN translation in replicative senescence
-
Ma L., Chang N., Guo S., Zhang Z., Wang W., Tong T. CSIG regulates PTEN translation in replicative senescence. Mol. Cell. Biol. 2008, 28:6290-6301.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 6290-6301
-
-
Ma, L.1
Chang, N.2
Guo, S.3
Zhang, Z.4
Wang, W.5
Tong, T.6
-
47
-
-
77957566465
-
MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence
-
Marasa B.S., Srikantan S., Martindale J.L., Kim M.M., Lee E.K., Gorospe M., Abdelmohsen K. MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence. Aging (Albany NY) 2010, 2:333-343.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 333-343
-
-
Marasa, B.S.1
Srikantan, S.2
Martindale, J.L.3
Kim, M.M.4
Lee, E.K.5
Gorospe, M.6
Abdelmohsen, K.7
-
48
-
-
77953583304
-
Tissue- and age-dependent expression of RNA-binding proteins that influence mRNA turnover and translation
-
Masuda K., Marasa B., Martindale J.L., Halushka M.K., Gorospe M. Tissue- and age-dependent expression of RNA-binding proteins that influence mRNA turnover and translation. Aging (Albany NY) 2009, 1:681-698.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 681-698
-
-
Masuda, K.1
Marasa, B.2
Martindale, J.L.3
Halushka, M.K.4
Gorospe, M.5
-
49
-
-
79952754428
-
Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation
-
Masuda K., Abdelmohsen K., Kim M.M., Srikantan S., Lee E.K., Tominaga K., Selimyan R., Martindale J.L., Yang X., Lehrmann E., Zhang Y., Becker K.G., Wang J.Y., Kim H.H., Gorospe M. Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation. EMBO J. 2011, 30:1040-1053.
-
(2011)
EMBO J.
, vol.30
, pp. 1040-1053
-
-
Masuda, K.1
Abdelmohsen, K.2
Kim, M.M.3
Srikantan, S.4
Lee, E.K.5
Tominaga, K.6
Selimyan, R.7
Martindale, J.L.8
Yang, X.9
Lehrmann, E.10
Zhang, Y.11
Becker, K.G.12
Wang, J.Y.13
Kim, H.H.14
Gorospe, M.15
-
50
-
-
38349047829
-
Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis
-
Mazroui R., Di Marco S., Clair E., von Roretz C., Tenenbaum S.A., Keene J.D., Saleh M., Gallouzi I.E. Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis. J. Cell Biol. 2008, 180:113-127.
-
(2008)
J. Cell Biol.
, vol.180
, pp. 113-127
-
-
Mazroui, R.1
Di Marco, S.2
Clair, E.3
von Roretz, C.4
Tenenbaum, S.A.5
Keene, J.D.6
Saleh, M.7
Gallouzi, I.E.8
-
51
-
-
0033864096
-
A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA
-
Millard S.S., Vidal A., Markus M., Koff A. A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA. Mol. Cell. Biol. 2000, 20:5947-5959.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5947-5959
-
-
Millard, S.S.1
Vidal, A.2
Markus, M.3
Koff, A.4
-
52
-
-
41649094992
-
SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity
-
Narala S.R., Allsopp R.C., Wells T.B., Zhang G., Prasad P., Coussens M.J., Rossi D.J., Weissman I.L., Vaziri H. SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity. Mol. Biol. Cell 2008, 19:1210-1219.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 1210-1219
-
-
Narala, S.R.1
Allsopp, R.C.2
Wells, T.B.3
Zhang, G.4
Prasad, P.5
Coussens, M.J.6
Rossi, D.J.7
Weissman, I.L.8
Vaziri, H.9
-
53
-
-
79951912532
-
Four faces of cellular senescence
-
Rodier F., Campici J. Four faces of cellular senescence. J. Cell Biol. 2011, 192:547-556.
-
(2011)
J. Cell Biol.
, vol.192
, pp. 547-556
-
-
Rodier, F.1
Campici, J.2
-
54
-
-
44949120812
-
Ectopic expression of cyclin D3 corrects differentiation of DM1 myoblasts through activation of RNA CUG-binding protein, CUGBP1
-
Salisbury E., Sakai K., Schoser B., Huichalaf C., Schneider-Gold C., Nguyen H., Wang G.L., Albrecht J.H., Timchenko L.T. Ectopic expression of cyclin D3 corrects differentiation of DM1 myoblasts through activation of RNA CUG-binding protein, CUGBP1. Exp. Cell Res. 2008, 314:2266-2278.
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 2266-2278
-
-
Salisbury, E.1
Sakai, K.2
Schoser, B.3
Huichalaf, C.4
Schneider-Gold, C.5
Nguyen, H.6
Wang, G.L.7
Albrecht, J.H.8
Timchenko, L.T.9
-
55
-
-
77955727216
-
The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase
-
Sanduja S., Kaza V., Dixon D.A. The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase. Aging (Albany NY) 2009, 1:803-817.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 803-817
-
-
Sanduja, S.1
Kaza, V.2
Dixon, D.A.3
-
56
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
Sherr C.J., Roberts J.M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 2012, 9:1149-11163.
-
(2012)
Genes Dev.
, vol.9
, pp. 1149-11163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
57
-
-
0029016832
-
Phosphorylation of tristetraprolin, a potential zinc finger transcription factor, by mitogen stimulation in intact cells and by mitogen-activated protein kinase in vitro
-
Taylor G.A., Thompson M.J., Lai W.S., Blackshear P.J. Phosphorylation of tristetraprolin, a potential zinc finger transcription factor, by mitogen stimulation in intact cells and by mitogen-activated protein kinase in vitro. J. Biol. Chem. 1995, 270:13341-13347.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13341-13347
-
-
Taylor, G.A.1
Thompson, M.J.2
Lai, W.S.3
Blackshear, P.J.4
-
59
-
-
33845922855
-
Age-specific CUGBP1-eIF2 complex increases translation of CCAAT/enhancer-binding protein beta in old liver
-
Timchenko L.T., Salisbury E., Wang G.L., Nguyen H., Albrecht J.H., Hershey J.W., Timchenko N.A. Age-specific CUGBP1-eIF2 complex increases translation of CCAAT/enhancer-binding protein beta in old liver. J. Biol. Chem. 2006, 281:32806-32819.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 32806-32819
-
-
Timchenko, L.T.1
Salisbury, E.2
Wang, G.L.3
Nguyen, H.4
Albrecht, J.H.5
Hershey, J.W.6
Timchenko, N.A.7
-
60
-
-
38649132594
-
Conserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1
-
Vlasova I.A., Tahoe N.M., Fan D., Larsson O., Rattenbacher B., Sternjohn J.R., Vasdewani J., Karypis G., Reilly C.S., Bitterman P.B., Bohjanen P.R. Conserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1. Mol. Cell 2008, 29:263-270.
-
(2008)
Mol. Cell
, vol.29
, pp. 263-270
-
-
Vlasova, I.A.1
Tahoe, N.M.2
Fan, D.3
Larsson, O.4
Rattenbacher, B.5
Sternjohn, J.R.6
Vasdewani, J.7
Karypis, G.8
Reilly, C.S.9
Bitterman, P.B.10
Bohjanen, P.R.11
-
61
-
-
0033959125
-
HuR regulates p21 mRNA Stabilization by Ultraviolet light
-
Wang W., Furneaux H., Caldwell M.C., Hutter C., Holbrook N., Gorospe M. HuR regulates p21 mRNA Stabilization by Ultraviolet light. Mol. Cell. Biol. 2000, 20:760-769.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 760-769
-
-
Wang, W.1
Furneaux, H.2
Caldwell, M.C.3
Hutter, C.4
Holbrook, N.5
Gorospe, M.6
-
62
-
-
0034908634
-
Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence
-
Wang W., Yang X., Cristofalo V., Holbrook N., Gorospe M. Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence. Mol. Cell. Biol. 2001, 21:5889-5898.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5889-5898
-
-
Wang, W.1
Yang, X.2
Cristofalo, V.3
Holbrook, N.4
Gorospe, M.5
-
63
-
-
0036238675
-
AMP-activated kinase regulates cytoplasm HuR
-
Wang W., Fan J., Yang X., Furer-Galban S., Lopez I., Kobbe C., Guo J., Georas S., Foufelle F., Hardie D., Carking D., Gorospe M. AMP-activated kinase regulates cytoplasm HuR. Mol. Cell. Biol. 2002, 22:3425-3436.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3425-3436
-
-
Wang, W.1
Fan, J.2
Yang, X.3
Furer-Galban, S.4
Lopez, I.5
Kobbe, C.6
Guo, J.7
Georas, S.8
Foufelle, F.9
Hardie, D.10
Carking, D.11
Gorospe, M.12
-
64
-
-
0038035142
-
In creased AMP: ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function
-
Wang W., Yang X., Lopez I., Carking D., Gorospe M. In creased AMP: ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function. J. Biol. Chem. 2003, 278:27016-27023.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27016-27023
-
-
Wang, W.1
Yang, X.2
Lopez, I.3
Carking, D.4
Gorospe, M.5
-
65
-
-
9144266386
-
AMPK-regulated acetylation and phosphorylation of importin-α1: involvement in the nuclear import of RNA-binding protein HuR
-
Wang W., Yang X., Kawai T., Lopez De Silanes I., Mazan-Mamczarz K., Chen P., Chook Y., Quensel C., Kohler M., Gorospe M. AMPK-regulated acetylation and phosphorylation of importin-α1: involvement in the nuclear import of RNA-binding protein HuR. J. Biol. Chem. 2004, 279:48376-48388.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 48376-48388
-
-
Wang, W.1
Yang, X.2
Kawai, T.3
Lopez De Silanes, I.4
Mazan-Mamczarz, K.5
Chen, P.6
Chook, Y.7
Quensel, C.8
Kohler, M.9
Gorospe, M.10
-
66
-
-
14644422293
-
AUF1-mediated mRNA turnover is responsible for up-regulation of p16 during replicative senescence
-
Wang W., Yang X., Martindale J., Gorospe M. AUF1-mediated mRNA turnover is responsible for up-regulation of p16 during replicative senescence. EMBO Rep. 2005, 6:158-164.
-
(2005)
EMBO Rep.
, vol.6
, pp. 158-164
-
-
Wang, W.1
Yang, X.2
Martindale, J.3
Gorospe, M.4
-
67
-
-
0029944622
-
Differential CDK-inhibitor gene expression in aging human diploid fibroblasts
-
Wong H., Riabowol K. Differential CDK-inhibitor gene expression in aging human diploid fibroblasts. Exp. Gerontol. 1996, 31:311-325.
-
(1996)
Exp. Gerontol.
, vol.31
, pp. 311-325
-
-
Wong, H.1
Riabowol, K.2
-
68
-
-
0042377361
-
Phosphorylation of p40AUF1 regulates binding to A+U-rich mRNA-destabilizing elements and protein-induced changes in ribonucleoprotein structure
-
Wilson G.M., Lu J., Sutphen K., Suarez Y., Sinha S., Brewer B., Villanueva-Feliciano E.C., Ysla R.M., Charles S., Brewer G. Phosphorylation of p40AUF1 regulates binding to A+U-rich mRNA-destabilizing elements and protein-induced changes in ribonucleoprotein structure. J. Biol. Chem. 2003, 278:33039-33048.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33039-33048
-
-
Wilson, G.M.1
Lu, J.2
Sutphen, K.3
Suarez, Y.4
Sinha, S.5
Brewer, B.6
Villanueva-Feliciano, E.C.7
Ysla, R.M.8
Charles, S.9
Brewer, G.10
-
69
-
-
0030330783
-
Regulation of transcription factor activity during cellular aging
-
Wheaton K., Atadja P., Riabowol K. Regulation of transcription factor activity during cellular aging. Biochem. Cell Biol. 1996, 74:523-534.
-
(1996)
Biochem. Cell Biol.
, vol.74
, pp. 523-534
-
-
Wheaton, K.1
Atadja, P.2
Riabowol, K.3
-
70
-
-
77950482789
-
Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence
-
Yi J., Chang N., Liu X., Guo G., Xue L., Tong T., Gorospe M., Wang W. Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence. Nucleic Acids Res. 2010, 38:1547-1558.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 1547-1558
-
-
Yi, J.1
Chang, N.2
Liu, X.3
Guo, G.4
Xue, L.5
Tong, T.6
Gorospe, M.7
Wang, W.8
-
71
-
-
84859168499
-
NSun2 stabilizes p16INK4 mRNA by methylating the p16 3'UTR
-
Zhang X., Liu Z., Yi J., Tang H., Xing J., Yu M., Tong T., Shang Y., Gorospe M., Wang W. NSun2 stabilizes p16INK4 mRNA by methylating the p16 3'UTR. Nat. Commun. 2012, 10.1038/ncomms1692.
-
(2012)
Nat. Commun.
-
-
Zhang, X.1
Liu, Z.2
Yi, J.3
Tang, H.4
Xing, J.5
Yu, M.6
Tong, T.7
Shang, Y.8
Gorospe, M.9
Wang, W.10
-
72
-
-
79956083367
-
CUG-binding protein represses translation of p27Kip1 mRNA through its internal ribosomal entry site
-
Zheng Y., Miskimins W.K. CUG-binding protein represses translation of p27Kip1 mRNA through its internal ribosomal entry site. RNA Biol. 2011, 8:365-371.
-
(2011)
RNA Biol.
, vol.8
, pp. 365-371
-
-
Zheng, Y.1
Miskimins, W.K.2
|