-
2
-
-
79952346767
-
Susceptibility of clinical Mycobacterium tuberculosis isolates to a potentially less toxic derivate of linezolid, PNU-100480
-
Alffenaar J. van der Laan T. Simons S. van der Werf T. van de Kasteele P. de Neeling H. (2011) Susceptibility of clinical Mycobacterium tuberculosis isolates to a potentially less toxic derivate of linezolid, PNU-100480. Antimicrob Agents Chemother 55: 1287–1289.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 1287-1289
-
-
Alffenaar, J.1
van der Laan, T.2
Simons, S.3
van der Werf, T.4
van de Kasteele, P.5
de Neeling, H.6
-
3
-
-
77950849122
-
Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!
-
Amaral L. Boeree M. Gillespie S. Udwadia Z. van Soolingen D. (2010) Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now! Int J Antimicrob Agents 35: 524–526.
-
(2010)
Int J Antimicrob Agents
, vol.35
, pp. 524-526
-
-
Amaral, L.1
Boeree, M.2
Gillespie, S.3
Udwadia, Z.4
van Soolingen, D.5
-
4
-
-
0034072946
-
Phenothiazines: an alternative to conventional therapy for the initial management of suspected multidrug resistant tuberculosis. A call for studies
-
Amaral L. Kristiansen J. (2000) Phenothiazines: an alternative to conventional therapy for the initial management of suspected multidrug resistant tuberculosis. A call for studies. Int J Antimicrob Agents 14: 173–176.
-
(2000)
Int J Antimicrob Agents
, vol.14
, pp. 173-176
-
-
Amaral, L.1
Kristiansen, J.2
-
5
-
-
52449123326
-
Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps
-
Amaral L. Martinds M. Viveiros M. Molnar J. Kristiansen J. (2008) Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps. Curr Drug Targets 9: 816–819.
-
(2008)
Curr Drug Targets
, vol.9
, pp. 816-819
-
-
Amaral, L.1
Martinds, M.2
Viveiros, M.3
Molnar, J.4
Kristiansen, J.5
-
7
-
-
77952564621
-
Linezolid use for treatment of multidrug-resistant and extensively drug-resistant tuberculosis, New York City, 2000–06
-
Anger H. Dworkin F. Sharma S. Munsiff S. Nilsen D. Ahuja S. (2010) Linezolid use for treatment of multidrug-resistant and extensively drug-resistant tuberculosis, New York City, 2000–06. J Antimicrob Chemother 65: 775–783.
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 775-783
-
-
Anger, H.1
Dworkin, F.2
Sharma, S.3
Munsiff, S.4
Nilsen, D.5
Ahuja, S.6
-
9
-
-
47749152561
-
Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding
-
Bashiri G. Squire C. Moreland N. Baker E. (2008) Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding. J Biol Chem 283: 17531–17541.
-
(2008)
J Biol Chem
, vol.283
, pp. 17531-17541
-
-
Bashiri, G.1
Squire, C.2
Moreland, N.3
Baker, E.4
-
11
-
-
77951782678
-
Rip van Winkle wakes up: development of tuberculosis treatment in the 21st century
-
(, Suppl. 3, ):
-
Burman W. (2010) Rip van Winkle wakes up: development of tuberculosis treatment in the 21st century. Clin Infect Dis 50(Suppl. 3): S165's172.
-
(2010)
Clin Infect Dis
, vol.50
, pp. S165-S172
-
-
Burman, W.1
-
13
-
-
77955872446
-
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis
-
Caminero J. Sotgiu G. Zumla A. Migliori G. (2010) Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis. Lancet Infect Dis 10: 621–629.
-
(2010)
Lancet Infect Dis
, vol.10
, pp. 621-629
-
-
Caminero, J.1
Sotgiu, G.2
Zumla, A.3
Migliori, G.4
-
14
-
-
4043181220
-
In-vitro activity of rifabutin against rifampicin-resistant Mycobacterium tuberculosis isolates with known rpoβ mutations
-
Cavusoglu C. Karaca-Derici Y. Bilgic A. (2004) In-vitro activity of rifabutin against rifampicin-resistant Mycobacterium tuberculosis isolates with known rpoβ mutations. Clin Microbiol Infect 10: 662–665.
-
(2004)
Clin Microbiol Infect
, vol.10
, pp. 662-665
-
-
Cavusoglu, C.1
Karaca-Derici, Y.2
Bilgic, A.3
-
15
-
-
77951195737
-
Newer fluoroquinolones for treating respiratory tract infection: do they mask tuberculosis?
-
Chang K. Leung C. Yew W. Lau T. Leung W. Tam C. (2010) Newer fluoroquinolones for treating respiratory tract infection: do they mask tuberculosis? Eur Respir J 35: 606–613.
-
(2010)
Eur Respir J
, vol.35
, pp. 606-613
-
-
Chang, K.1
Leung, C.2
Yew, W.3
Lau, T.4
Leung, W.5
Tam, C.6
-
16
-
-
33748040742
-
Synergistic interactions of SQ109, a new ethylene diamine, with front-line antitubercular drugs in vitro
-
Chen P. Gearhart J. Protopopova M. Einck L. Nacy C. (2006) Synergistic interactions of SQ109, a new ethylene diamine, with front-line antitubercular drugs in vitro. J Antimicrob Chemother 58: 332–337.
-
(2006)
J Antimicrob Chemother
, vol.58
, pp. 332-337
-
-
Chen, P.1
Gearhart, J.2
Protopopova, M.3
Einck, L.4
Nacy, C.5
-
17
-
-
77950214679
-
Drug-resistant tuberculosis: past, present and future
-
Chiang C. Centis R. Migliori G. (2010) Drug-resistant tuberculosis: past, present and future. Respirology 15: 413–432.
-
(2010)
Respirology
, vol.15
, pp. 413-432
-
-
Chiang, C.1
Centis, R.2
Migliori, G.3
-
18
-
-
20144387448
-
The Mycobacterium tuberculosis iniA gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol
-
Colangeli R. Helb D. Sridharan S. Sun J. Varma-Basil M. Hazbon M. (2005) The Mycobacterium tuberculosis iniA gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol. Mol Microbiol 55: 1829–1840.
-
(2005)
Mol Microbiol
, vol.55
, pp. 1829-1840
-
-
Colangeli, R.1
Helb, D.2
Sridharan, S.3
Sun, J.4
Varma-Basil, M.5
Hazbon, M.6
-
19
-
-
80053902179
-
New tuberculosis drugs on the horizon
-
Cole S. Riccardi G. (2011) New tuberculosis drugs on the horizon. Curr Opin Micobiol 14: 570–576.
-
(2011)
Curr Opin Micobiol
, vol.14
, pp. 570-576
-
-
Cole, S.1
Riccardi, G.2
-
20
-
-
47549119545
-
Case series of a linezolid-containing regimen for extensively drug-resistant tuberculosis
-
Condos R. Hadgiangelis N. Leibert E. Jacquette G. Harkin T. Rom W. (2008) Case series of a linezolid-containing regimen for extensively drug-resistant tuberculosis. Chest 134: 187–192.
-
(2008)
Chest
, vol.134
, pp. 187-192
-
-
Condos, R.1
Hadgiangelis, N.2
Leibert, E.3
Jacquette, G.4
Harkin, T.5
Rom, W.6
-
22
-
-
77957205232
-
Bacterial activity of the diarylquinoline TMC207 against Mycobacterium tuberculosis outside and within cells
-
Dhillon J. Andries K. Phillips P. Mitchison D. (2010) Bacterial activity of the diarylquinoline TMC207 against Mycobacterium tuberculosis outside and within cells. Tuberculosis 90: 301–350.
-
(2010)
Tuberculosis
, vol.90
, pp. 301-350
-
-
Dhillon, J.1
Andries, K.2
Phillips, P.3
Mitchison, D.4
-
24
-
-
34547620711
-
Early bactericidal activity of high-dose rifampin in patients with pulmonary tuberculosis evidenced by positive sputum smears
-
Diacon A. Patientia R. Venter A. van Helden P. Smith P. McIlleron H. (2007) Early bactericidal activity of high-dose rifampin in patients with pulmonary tuberculosis evidenced by positive sputum smears. Antimicrobial Agents Chemother 51: 2994–2996.
-
(2007)
Antimicrobial Agents Chemother
, vol.51
, pp. 2994-2996
-
-
Diacon, A.1
Patientia, R.2
Venter, A.3
van Helden, P.4
Smith, P.5
McIlleron, H.6
-
27
-
-
50649089808
-
The early bactericidal activity of anti-tuberculosis drugs: a literature review
-
(, Suppl. 1, ):
-
Donald P. Diacon A. (2008) The early bactericidal activity of anti-tuberculosis drugs: a literature review. Tuberculosis 88(Suppl. 1): S75's83.
-
(2008)
Tuberculosis
, vol.88
, pp. S75-S83
-
-
Donald, P.1
Diacon, A.2
-
29
-
-
33745726538
-
Impact of bacterial genetics on the transmission of isoniazid resistant Mycobacterium tuberculosis
-
Gagneux S. Burgos M. DeRiemer K. Enciso A. Munoz S. Hopewell P. (2006) Impact of bacterial genetics on the transmission of isoniazid resistant Mycobacterium tuberculosis. PLoS Pathogens 2: e61.
-
(2006)
PLoS Pathogens
, vol.2
, pp. e61
-
-
Gagneux, S.1
Burgos, M.2
DeRiemer, K.3
Enciso, A.4
Munoz, S.5
Hopewell, P.6
-
30
-
-
78649654380
-
Strong in vitro activities of two new rifabutin analogues against multidrug-resistant Mycobacterium tuberculosis
-
Garcia A. Palacios J. Ruiz M. Barluenga J. Aznar F. Caba M. (2010) Strong in vitro activities of two new rifabutin analogues against multidrug-resistant Mycobacterium tuberculosis. Antimicrobiol Agents Chemother 54: 5363–5365.
-
(2010)
Antimicrobiol Agents Chemother
, vol.54
, pp. 5363-5365
-
-
Garcia, A.1
Palacios, J.2
Ruiz, M.3
Barluenga, J.4
Aznar, F.5
Caba, M.6
-
31
-
-
0036150240
-
Evolution of drug resistance in Mycobacterium tuberculosis: clinical and molecular perspective
-
Gillespie S. (2002) Evolution of drug resistance in Mycobacterium tuberculosis: clinical and molecular perspective. Antimicrob Agents Chemother 46: 267–274.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 267-274
-
-
Gillespie, S.1
-
32
-
-
70349136685
-
Assessment of the effects of the nitroimidazo-oxazine, PA-824, on renal function in healthy subjects
-
Ginsburg A. Laurenzi M. Rouse D. Whitney K. Spigelman M. (2009) Assessment of the effects of the nitroimidazo-oxazine, PA-824, on renal function in healthy subjects. Antimicrob Agents Chemother 53: 3726–3733.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 3726-3733
-
-
Ginsburg, A.1
Laurenzi, M.2
Rouse, D.3
Whitney, K.4
Spigelman, M.5
-
34
-
-
43249087251
-
SQ109
-
Global Alliance for TB Drug Development (2008) SQ109. Tuberculosis 88: 159–161.
-
(2008)
Tuberculosis
, vol.88
, pp. 159-161
-
-
-
35
-
-
0035857774
-
Linezolid and reversible myelosuppression
-
Green S. Maddo J. Huttenbach E. (2001) Linezolid and reversible myelosuppression. JAMA 285: 1291.
-
(2001)
JAMA
, vol.285
, pp. 1291
-
-
Green, S.1
Maddo, J.2
Huttenbach, E.3
-
37
-
-
80051850771
-
Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase
-
Haagsma A. Podasca I. Koul A. Andries K. Guillemont J. Lill H. (2011) Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase. PLoS One 6: e23575.
-
(2011)
PLoS One
, vol.6
, pp. e23575
-
-
Haagsma, A.1
Podasca, I.2
Koul, A.3
Andries, K.4
Guillemont, J.5
Lill, H.6
-
38
-
-
0025361652
-
Bactericidal activity in vitro of various rifamycins against Mycobacterium avium and Mycobacterium tuberculosis
-
Heifets L. Lindholm-Levy P. Iseman M. (1990) Bactericidal activity in vitro of various rifamycins against Mycobacterium avium and Mycobacterium tuberculosis. Am Rev Respir Dis 141: 626–630.
-
(1990)
Am Rev Respir Dis
, vol.141
, pp. 626-630
-
-
Heifets, L.1
Lindholm-Levy, P.2
Iseman, M.3
-
39
-
-
38349010517
-
Comparison of the sterilizing activities of the nitroimidazopyran PA-824 and moxifloxacin against persisting Mycobacterium tuberculosis
-
Hu Y. Coates A. Mitchison D. (2008) Comparison of the sterilizing activities of the nitroimidazopyran PA-824 and moxifloxacin against persisting Mycobacterium tuberculosis. Int J Tuberc Lung Dis 12: 69–73.
-
(2008)
Int J Tuberc Lung Dis
, vol.12
, pp. 69-73
-
-
Hu, Y.1
Coates, A.2
Mitchison, D.3
-
41
-
-
77149123917
-
Rates and mechanisms of resistance development in Mycobacterium tuberculosis to a novel diaryquinoline ATP synthase inhibitor
-
Huitric E. Verhasselt P. Koul A. Andries K. Hoffner S. Andersson D. (2010) Rates and mechanisms of resistance development in Mycobacterium tuberculosis to a novel diaryquinoline ATP synthase inhibitor. Antimicrob Agents Chemother 54: 1022–1028.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 1022-1028
-
-
Huitric, E.1
Verhasselt, P.2
Koul, A.3
Andries, K.4
Hoffner, S.5
Andersson, D.6
-
46
-
-
13244283085
-
Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug
-
Jia L. Tomaszewski J. Harahan C. Coward L. Noker P. Gorman G. (2005) Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug. Br J Pharmacol 144: 80–87.
-
(2005)
Br J Pharmacol
, vol.144
, pp. 80-87
-
-
Jia, L.1
Tomaszewski, J.2
Harahan, C.3
Coward, L.4
Noker, P.5
Gorman, G.6
-
47
-
-
33744924880
-
Early and extended early bactericidal activity of levofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis
-
Johnson J. Hadad D. Boom W. Daley C. Peloquin C. Eisenach K. (2006) Early and extended early bactericidal activity of levofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis. Int J Tuber Lung Dis 10: 605–612.
-
(2006)
Int J Tuber Lung Dis
, vol.10
, pp. 605-612
-
-
Johnson, J.1
Hadad, D.2
Boom, W.3
Daley, C.4
Peloquin, C.5
Eisenach, K.6
-
48
-
-
67650730258
-
Daily 300 mg dose of linezolid for the treatment of intractable multidrug-resistant and extensively drug-resistant tuberculosis
-
Koh W. Kwon O. Gwak H. Chung J. Cho S. Kim W. (2009) Daily 300 mg dose of linezolid for the treatment of intractable multidrug-resistant and extensively drug-resistant tuberculosis. J Antimicrob Chemother 64: 388–391.
-
(2009)
J Antimicrob Chemother
, vol.64
, pp. 388-391
-
-
Koh, W.1
Kwon, O.2
Gwak, H.3
Chung, J.4
Cho, S.5
Kim, W.6
-
52
-
-
79959927732
-
Tuberculosis
-
Lawn S. Zumla A. (2011) Tuberculosis. Lancet 378: 57–72.
-
(2011)
Lancet
, vol.378
, pp. 57-72
-
-
Lawn, S.1
Zumla, A.2
-
53
-
-
79959818137
-
Retrospective comparison of levofloxacin and moxifloxacin on multidrug-resistant tuberculosis treatment outcomes
-
Lee J. Lee C. Kim D. Yoon H. Kim J. Lee S. (2011) Retrospective comparison of levofloxacin and moxifloxacin on multidrug-resistant tuberculosis treatment outcomes. Korean J Intern Med 26: 153–159.
-
(2011)
Korean J Intern Med
, vol.26
, pp. 153-159
-
-
Lee, J.1
Lee, C.2
Kim, D.3
Yoon, H.4
Kim, J.5
Lee, S.6
-
55
-
-
77951092627
-
New drugs and new regimens for the treatment of tuberculosis: review of the drug development pipeline and implications for national programmes
-
Lienhardt C. Vernon A. Raviglione M. (2010) New drugs and new regimens for the treatment of tuberculosis: review of the drug development pipeline and implications for national programmes. Curr Opin Pulm Med 16: 186–193.
-
(2010)
Curr Opin Pulm Med
, vol.16
, pp. 186-193
-
-
Lienhardt, C.1
Vernon, A.2
Raviglione, M.3
-
56
-
-
79960766385
-
Risk factors associated with fluoroquinolone-resistant tuberculosis in a Beijing tuberculosis referral hospital
-
Liu C. Yang N. Wang Q. Hu Y. Li L. Zhang G. (2011) Risk factors associated with fluoroquinolone-resistant tuberculosis in a Beijing tuberculosis referral hospital. Respirology 16: 918–925.
-
(2011)
Respirology
, vol.16
, pp. 918-925
-
-
Liu, C.1
Yang, N.2
Wang, Q.3
Hu, Y.4
Li, L.5
Zhang, G.6
-
57
-
-
54049095245
-
Impact of the interaction of R207910 with rifampin on the treatment of tuberculosis studied in the mouse model
-
Lounis N. Gevers T. van den Berg J. Andries K. (2008) Impact of the interaction of R207910 with rifampin on the treatment of tuberculosis studied in the mouse model. Antimicrob Agents Chemother 52: 3568–3572.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 3568-3572
-
-
Lounis, N.1
Gevers, T.2
van den Berg, J.3
Andries, K.4
-
58
-
-
77953475812
-
Global tuberculosis drug development pipeline: the need and the reality
-
Ma Z. Lienhardt C. McIlleron H. Nunn A. Wang X. (2010) Global tuberculosis drug development pipeline: the need and the reality. Lancet 375: 2100–2109.
-
(2010)
Lancet
, vol.375
, pp. 2100-2109
-
-
Ma, Z.1
Lienhardt, C.2
McIlleron, H.3
Nunn, A.4
Wang, X.5
-
60
-
-
24944456673
-
Levofloxacin treatment of active tuberculosis and the risk of adverse events
-
Marra F. Marra C. Moadebi S. Shi P. Elwood K. Stark G. (2005) Levofloxacin treatment of active tuberculosis and the risk of adverse events. Chest 128: 1406–1413.
-
(2005)
Chest
, vol.128
, pp. 1406-1413
-
-
Marra, F.1
Marra, C.2
Moadebi, S.3
Shi, P.4
Elwood, K.5
Stark, G.6
-
61
-
-
33845323336
-
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice
-
Matsumoto M. Hashizume H. Tomishige T. Kawasaki M. Tsubouchi H. Sasaki H. (2006) OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. PLoS Med 3: e466.
-
(2006)
PLoS Med
, vol.3
, pp. e466
-
-
Matsumoto, M.1
Hashizume, H.2
Tomishige, T.3
Kawasaki, M.4
Tsubouchi, H.5
Sasaki, H.6
-
63
-
-
69249137544
-
A retrospective TBNET assessment of linezolid safety, tolerability and efficacy in multidrug-resistant tuberculosis
-
Migliori G. Eker B. Richardson M. Sotgiu G. Zellweger J. Skrahina A. (2009) A retrospective TBNET assessment of linezolid safety, tolerability and efficacy in multidrug-resistant tuberculosis. Eur Respir J 34: 387–393.
-
(2009)
Eur Respir J
, vol.34
, pp. 387-393
-
-
Migliori, G.1
Eker, B.2
Richardson, M.3
Sotgiu, G.4
Zellweger, J.5
Skrahina, A.6
-
64
-
-
0033812380
-
Role of individual drugs in the chemotherapy of tuberculosis
-
Mitchison D. (2000) Role of individual drugs in the chemotherapy of tuberculosis. Int J Tuberc Lung Dis 4: 796–806.
-
(2000)
Int J Tuberc Lung Dis
, vol.4
, pp. 796-806
-
-
Mitchison, D.1
-
65
-
-
13844281903
-
Shortening the treatment of tuberculosis
-
Mitchison D. (2005) Shortening the treatment of tuberculosis. Nat Biotechnol 23: 187–188.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 187-188
-
-
Mitchison, D.1
-
66
-
-
77952584170
-
The near future: improving the activity of rifamycins and pyrazinamide
-
Mitchison D. Fourie P. (2010) The near future: improving the activity of rifamycins and pyrazinamide. Tuberculosis 90: 177–181.
-
(2010)
Tuberculosis
, vol.90
, pp. 177-181
-
-
Mitchison, D.1
Fourie, P.2
-
67
-
-
65649136872
-
Tuberculosis pharmacotherapy: strategies to optimize patient care
-
Mitnick C. McGee B. Peloquin C. (2009) Tuberculosis pharmacotherapy: strategies to optimize patient care. Expert Opin Pharmacother 10: 381–401.
-
(2009)
Expert Opin Pharmacother
, vol.10
, pp. 381-401
-
-
Mitnick, C.1
McGee, B.2
Peloquin, C.3
-
70
-
-
80052393888
-
Nitroimidazoles for the treatment of TB: past, present, and future
-
Mukherjee T. Boshoff H. (2011) Nitroimidazoles for the treatment of TB: past, present, and future. Future Med Chem 3: 1427–1454.
-
(2011)
Future Med Chem
, vol.3
, pp. 1427-1454
-
-
Mukherjee, T.1
Boshoff, H.2
-
71
-
-
59349113030
-
Daily half-dose linezolid for the treatment of intractable multi-drug resistant tuberculosis
-
Nam H. Koh W. Kwon O. Cho S. Shim T. (2009) Daily half-dose linezolid for the treatment of intractable multi-drug resistant tuberculosis. Int J Antimicrob Agents 33: 92–93.
-
(2009)
Int J Antimicrob Agents
, vol.33
, pp. 92-93
-
-
Nam, H.1
Koh, W.2
Kwon, O.3
Cho, S.4
Shim, T.5
-
73
-
-
34247127876
-
Drug therapy of experimental tuberculosis (TB): improved outcome by combining SQ109, a new diamine antibiotic, with existing TB drugs
-
Nikonenko B. Protopopova M. Samala R. Einck L. Nacy C. (2007) Drug therapy of experimental tuberculosis (TB): improved outcome by combining SQ109, a new diamine antibiotic, with existing TB drugs. Antimicrob Agents Chemother 51: 1563–1565.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 1563-1565
-
-
Nikonenko, B.1
Protopopova, M.2
Samala, R.3
Einck, L.4
Nacy, C.5
-
74
-
-
58349116822
-
Once-weekly treatment of tuberculosis with the diarylquinoline R207910. A real possibility
-
Nuermberger E. Mitchison D. (2009) Once-weekly treatment of tuberculosis with the diarylquinoline R207910. A real possibility. Am J Respir Crit Care Med 179: 2–3.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 2-3
-
-
Nuermberger, E.1
Mitchison, D.2
-
76
-
-
77953842683
-
Current development and future prospects in chemotherapy of tuberculosis
-
Nuermberger E. Spigelman M. Yew W. (2010) Current development and future prospects in chemotherapy of tuberculosis. Respirology 15: 764–778.
-
(2010)
Respirology
, vol.15
, pp. 764-778
-
-
Nuermberger, E.1
Spigelman, M.2
Yew, W.3
-
77
-
-
42049101775
-
Powerful bactericidal activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosis
-
Nuermberger E. Tyagi S. Tasneen R. Williams K. Almeida D. Rosenthal I. (2008) Powerful bactericidal activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosis. Antimicrob Agents Chemother 52: 1522–1524.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1522-1524
-
-
Nuermberger, E.1
Tyagi, S.2
Tasneen, R.3
Williams, K.4
Almeida, D.5
Rosenthal, I.6
-
79
-
-
81355160182
-
Novel linear diamine disubstituted polycyclic ‘cage’ derivatives as potential antimycobacterial candidates
-
Onajole O. Sosibo S. Govender P. Govender T. van Helden P. Maguire G. (2011) Novel linear diamine disubstituted polycyclic ‘cage’ derivatives as potential antimycobacterial candidates. Chem Biol Drug Des 78: 1022–1030.
-
(2011)
Chem Biol Drug Des
, vol.78
, pp. 1022-1030
-
-
Onajole, O.1
Sosibo, S.2
Govender, P.3
Govender, T.4
van Helden, P.5
Maguire, G.6
-
80
-
-
34248144307
-
NLCQ-1 and NLCQ-2, two new agents with activity against dormant Mycobacterium tuberculosis
-
Papadopoulou M. Bloomer W. McNeil M. (2007) NLCQ-1 and NLCQ-2, two new agents with activity against dormant Mycobacterium tuberculosis. Int J Antimicrob Agents 29: 724–727.
-
(2007)
Int J Antimicrob Agents
, vol.29
, pp. 724-727
-
-
Papadopoulou, M.1
Bloomer, W.2
McNeil, M.3
-
81
-
-
33747879490
-
Efficacy and tolerability of daily half-dose linezolid in patients with intractable multi-drug-resistant tuberculosis
-
Park I. Hong S. Oh Y. Kim M. Lim C. Lee S. (2006) Efficacy and tolerability of daily half-dose linezolid in patients with intractable multi-drug-resistant tuberculosis. J Antimicrob Chemother 58: 701–704.
-
(2006)
J Antimicrob Chemother
, vol.58
, pp. 701-704
-
-
Park, I.1
Hong, S.2
Oh, Y.3
Kim, M.4
Lim, C.5
Lee, S.6
-
83
-
-
27744496465
-
Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines
-
Protopopova M. Hanrahan C. Nikonenko B. Samala R. Chen P. Gearhart J. (2005) Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines. J Antimicrob Chemother 56: 968–974.
-
(2005)
J Antimicrob Chemother
, vol.56
, pp. 968-974
-
-
Protopopova, M.1
Hanrahan, C.2
Nikonenko, B.3
Samala, R.4
Chen, P.5
Gearhart, J.6
-
84
-
-
50149113470
-
The protonmotive force is required for ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis
-
Rao S. Alonso S. Rand L. Dick T. Pethe K. (2008) The protonmotive force is required for ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis. Proc Natl Acad Sci U S A 105: 11945–11950.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 11945-11950
-
-
Rao, S.1
Alonso, S.2
Rand, L.3
Dick, T.4
Pethe, K.5
-
85
-
-
77953797826
-
In vitro interactions between new antitubercular drug candidates SQ109 and TMC207
-
Reddy V. Andries L. Nacy C. (2010) In vitro interactions between new antitubercular drug candidates SQ109 and TMC207. Antimicrob Agents Chemother 54: 2840–2846.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2840-2846
-
-
Reddy, V.1
Andries, L.2
Nacy, C.3
-
86
-
-
38049038389
-
Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model
-
Rosenthal I. Zhang M. Williams K. Peloquin C. Tyagi S. Vernon A. (2007) Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model. PLoS Med 4: e344.
-
(2007)
PLoS Med
, vol.4
, pp. e344
-
-
Rosenthal, I.1
Zhang, M.2
Williams, K.3
Peloquin, C.4
Tyagi, S.5
Vernon, A.6
-
89
-
-
48749120676
-
Early bactericidal activity and pharmacokinetics of the diarylquinoline TMC207 in treatment of pulmonary tuberculosis
-
Rustomjee R. Diacon A. Allen J. Venter A. Reddy C. Patientia R. (2008) Early bactericidal activity and pharmacokinetics of the diarylquinoline TMC207 in treatment of pulmonary tuberculosis. Antimicrob Agents Chemother 52: 2831–2835.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 2831-2835
-
-
Rustomjee, R.1
Diacon, A.2
Allen, J.3
Venter, A.4
Reddy, C.5
Patientia, R.6
-
91
-
-
81555214621
-
Phenothiazines as anti-tubercular agents: mechanistic insights and clinical implications
-
Sharma S. Singh A. (2011) Phenothiazines as anti-tubercular agents: mechanistic insights and clinical implications. Expert Opin Investig Drugs 20: 1665–1676.
-
(2011)
Expert Opin Investig Drugs
, vol.20
, pp. 1665-1676
-
-
Sharma, S.1
Singh, A.2
-
92
-
-
77952366279
-
Development of new anti-tuberculosis drug candidates
-
Shi R. Sugawara I. (2010) Development of new anti-tuberculosis drug candidates. Tohoku J Exp Med 221: 97–106.
-
(2010)
Tohoku J Exp Med
, vol.221
, pp. 97-106
-
-
Shi, R.1
Sugawara, I.2
-
96
-
-
0034084624
-
The genetics and biochemistry of isoniazid resistance in Mycobacterium tuberculosis
-
Slayden R. Barry C. (2000) The genetics and biochemistry of isoniazid resistance in Mycobacterium tuberculosis. Microbes Infect 2: 659–669.
-
(2000)
Microbes Infect
, vol.2
, pp. 659-669
-
-
Slayden, R.1
Barry, C.2
-
97
-
-
34547619993
-
New tuberculosis therapeutics: a growing pipeline
-
(, Suppl. 1, ):
-
Spigelman M. (2007) New tuberculosis therapeutics: a growing pipeline. J Infect Dis 196(Suppl. 1): S28's34.
-
(2007)
J Infect Dis
, vol.196
, pp. S28-S34
-
-
Spigelman, M.1
-
100
-
-
81555211930
-
Current prospects for the fluoroquinolones as first-line tuberculosis therapy
-
Takiff H. Guerrero E. (2011) Current prospects for the fluoroquinolones as first-line tuberculosis therapy. Antimicrob Agents Chemother 55: 5421–5429.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 5421-5429
-
-
Takiff, H.1
Guerrero, E.2
-
101
-
-
82355164493
-
Efficacy and safety of linezolid in the treatment of extensively drug-resistant tuberculosis
-
Tang S. Zhang Q. Zeng L. Sun H. Gu J. Hao X. (2011) Efficacy and safety of linezolid in the treatment of extensively drug-resistant tuberculosis. Jpn J Infect Dis 64: 509–512.
-
(2011)
Jpn J Infect Dis
, vol.64
, pp. 509-512
-
-
Tang, S.1
Zhang, Q.2
Zeng, L.3
Sun, H.4
Gu, J.5
Hao, X.6
-
105
-
-
0036204223
-
Investigation of cross-resistance between rifampin and rifabutin in Mycobacterium tuberculosis complex strains
-
Uzun M. Enturan Z. Ang O. (2002) Investigation of cross-resistance between rifampin and rifabutin in Mycobacterium tuberculosis complex strains. Int J Tuberc Lung Dis 6: 164–165.
-
(2002)
Int J Tuberc Lung Dis
, vol.6
, pp. 164-165
-
-
Uzun, M.1
Enturan, Z.2
Ang, O.3
-
106
-
-
62949092917
-
New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development
-
van den Boogard J. Kibiki G. Kisanga E. Boeree M. Aarnoutse R. (2009) New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development. Antimicrob Agents Chemother 53: 849–862.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 849-862
-
-
van den Boogard, J.1
Kibiki, G.2
Kisanga, E.3
Boeree, M.4
Aarnoutse, R.5
-
107
-
-
84861910391
-
Multidrug resistance after inappropriate tuberculosis treatment: a meta-analysis
-
van der Werf M. Langendam M. Huitric E. Manissero D. (2012) Multidrug resistance after inappropriate tuberculosis treatment: a meta-analysis. Eur Respir J 39: 1511–1519.
-
(2012)
Eur Respir J
, vol.39
, pp. 1511-1519
-
-
van der Werf, M.1
Langendam, M.2
Huitric, E.3
Manissero, D.4
-
108
-
-
77952365008
-
Short, highly effective, and inexpensive standardized treatment of multi-drug resistant tuberculosis
-
Van Deun A. Maug A. Salim M. Das P. Sarker M. Daru P. (2010) Short, highly effective, and inexpensive standardized treatment of multi-drug resistant tuberculosis. Am J Respir Crit Care Med 182: 684–692.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 684-692
-
-
Van Deun, A.1
Maug, A.2
Salim, M.3
Das, P.4
Sarker, M.5
Daru, P.6
-
110
-
-
68849127471
-
Emergence of new forms of totally drug-resistant tuberculosis bacilli: super extensively drug-resistant tuberculosis or totally drug-resistant strains in Iran
-
Velayati A. Masjed M. Farnia P. Tabarsi P. Ghanavi J. ZiaZarifi A. (2009) Emergence of new forms of totally drug-resistant tuberculosis bacilli: super extensively drug-resistant tuberculosis or totally drug-resistant strains in Iran. Chest 136: 420–425.
-
(2009)
Chest
, vol.136
, pp. 420-425
-
-
Velayati, A.1
Masjed, M.2
Farnia, P.3
Tabarsi, P.4
Ghanavi, J.5
ZiaZarifi, A.6
-
111
-
-
68549089180
-
Antitubercular activity of α,ω-diaminoalkanes, H2N(CH2)nNH2
-
Vergara F. Henriques M. Candea A. Wardell J. de Souza M. (2009) Antitubercular activity of α,ω-diaminoalkanes, H2N(CH2)nNH2. Biorg Med Chem Lett 19: 4937–4938.
-
(2009)
Biorg Med Chem Lett
, vol.19
, pp. 4937-4938
-
-
Vergara, F.1
Henriques, M.2
Candea, A.3
Wardell, J.4
de Souza, M.5
-
112
-
-
79952422865
-
Sterilizing activity of second-line regimens containing TMC207 in a murine model of tuberculosis
-
Veziris N. Ibrahim M. Lounis N. Andries K. Jarlier V. (2011) Sterilizing activity of second-line regimens containing TMC207 in a murine model of tuberculosis. PLos One 6: e17556.
-
(2011)
PLos One
, vol.6
, pp. e17556
-
-
Veziris, N.1
Ibrahim, M.2
Lounis, N.3
Andries, K.4
Jarlier, V.5
-
113
-
-
31344480688
-
Efficacy and safety of linezolid in multidrug resistant tuberculosis (MDR-TB)–a report of ten cases
-
von der Lippe B. Sandven P. Brubakk O. (2006) Efficacy and safety of linezolid in multidrug resistant tuberculosis (MDR-TB)–a report of ten cases. J Infect 52: 92–96.
-
(2006)
J Infect
, vol.52
, pp. 92-96
-
-
von der Lippe, B.1
Sandven, P.2
Brubakk, O.3
-
114
-
-
77950344967
-
Terizidone
-
Vora A. (2010) Terizidone. JAPI 58: 267–268.
-
(2010)
JAPI
, vol.58
, pp. 267-268
-
-
Vora, A.1
-
117
-
-
65649089528
-
Promising antituberculosis activity of the oxazolidinone PNU-100480 relative to that of linezolid in a murine model
-
Williams K. Stover C. Zhu T. Tasneen R. Tyagi S. Grosset J. (2009b) Promising antituberculosis activity of the oxazolidinone PNU-100480 relative to that of linezolid in a murine model. Antimicrob Agents Chemother 53: 1314–1319.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 1314-1319
-
-
Williams, K.1
Stover, C.2
Zhu, T.3
Tasneen, R.4
Tyagi, S.5
Grosset, J.6
-
118
-
-
0003895308
-
-
Report No. 4., WHO/IUATLD global project on anti-tuberculous drug resistance surveillance. Geneva, accessed 12 June 2012
-
World Health Organization (2008a) Anti-tuberculosis Drug Resistance in the World. Report No. 4. WHO/IUATLD global project on anti-tuberculous drug resistance surveillance. Geneva. http://whqlibdoc.who.int/hq/2008/WHO_HTM_TB_2008.394_eng.pdf ( accessed 12 June 2012).
-
(2008)
Anti-tuberculosis Drug Resistance in the World
-
-
-
119
-
-
33645581396
-
-
Emergency update 2008., Geneva, accessed 4 June 2012
-
World Health Organization (2008b) Guidelines for the Programmic Management of Drug-resistant Tuberculosis. Emergency update 2008. Geneva. http://whqlibdoc.who.int/publications/2008/9789241547581_eng.pdf ( accessed 4 June 2012).
-
(2008)
Guidelines for the Programmic Management of Drug-resistant Tuberculosis
-
-
-
120
-
-
77954453440
-
-
2010 Global report on surveillance and response., Geneva, accessed 12 June 2012
-
World Health Organization (2010) Multidrug and Extensively Drug-resistant TB (M/XDR-TB). 2010 Global report on surveillance and response. Geneva. http://www.WHO/HTM/TB/2010.3 ( accessed 12 June 2012).
-
(2010)
Multidrug and Extensively Drug-resistant TB (M/XDR-TB)
-
-
-
122
-
-
84993693583
-
-
2011 progress report., accessed 12 June 2012
-
World Health Organization (2011b) Tuberculosis MDR-TB and XDR-TB 2011 progress report. http://www.who.int/tb/challenges/mdr/factsheet_mdr_progress_march2011.pdf ( accessed 12 June 2012).
-
(2011)
Tuberculosis MDR-TB and XDR-TB
-
-
-
124
-
-
38049098158
-
Management of multi-drug resistant tuberculosis: update 2007
-
Yew W. Leung C. (2008) Management of multi-drug resistant tuberculosis: update 2007. Respirology 13: 21–46.
-
(2008)
Respirology
, vol.13
, pp. 21-46
-
-
Yew, W.1
Leung, C.2
-
125
-
-
78149415966
-
Comparison of rifabutin susceptibility and rpoβ mutations in multi-drug-resistant Mycobacterium tuberculosis strains by DNA sequencing and the line probe assay
-
Yoshida S. Suzuki K. Iwamoto T. Tsuyuguchi K. Tomita M. Okada M. (2010) Comparison of rifabutin susceptibility and rpoβ mutations in multi-drug-resistant Mycobacterium tuberculosis strains by DNA sequencing and the line probe assay. J Infect Chemother 16: 360–363.
-
(2010)
J Infect Chemother
, vol.16
, pp. 360-363
-
-
Yoshida, S.1
Suzuki, K.2
Iwamoto, T.3
Tsuyuguchi, K.4
Tomita, M.5
Okada, M.6
-
126
-
-
73949101816
-
Mechanisms of drug resistance in Mycobacterium tuberculosis
-
Zhang Y. Yew W. (2009) Mechanisms of drug resistance in Mycobacterium tuberculosis. Int J Tuberc Lung Dis 13: 1320–1330.
-
(2009)
Int J Tuberc Lung Dis
, vol.13
, pp. 1320-1330
-
-
Zhang, Y.1
Yew, W.2
|