Efficacy and safety of linezolid in multidrug resistant tuberculosis (MDR-TB) - A report of ten cases

Journal of Infection

Volumn 52, Issue 2, 2006, Pages 92-96

  von der Lippe, Bent ^a   Sandven, Per ^b   Brubakk, Oddbjoørn ^a  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Linezolid; MDR TB; Myelosuppression; Peripheral neuropathy

Indexed keywords

AMIKACIN; AMINOSALICYLIC ACID; AMOXICILLIN PLUS CLAVULANIC ACID; CAPREOMYCIN; CIPROFLOXACIN; CLOFAZIMINE; CYCLOSERINE; ETHAMBUTOL; ETHIONAMIDE; ISONIAZID; LINEZOLID; OFLOXACIN; PYRAZINAMIDE; QUINOLONE DERIVATIVE; RIFAMPICIN; STREPTOMYCIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ANEMIA; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; BLOOD TRANSFUSION; BONE MARROW DEPRESSION; CLINICAL ARTICLE; COMORBIDITY; CONCENTRATION RESPONSE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOLLOW UP; GASTROCNEMIUS MUSCLE; HUMAN; LEG PAIN; LEUKOPENIA; MALE; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; MULTIDRUG RESISTANCE; MUSCLE WEAKNESS; NEUROGRAPHY; NORWAY; PARESTHESIA; PATIENT COMPLIANCE; PERIPHERAL NEUROPATHY; POLYNEUROPATHY; RADICULITIS; SHORT COURSE THERAPY; SPUTUM CULTURE; THROMBOCYTOPENIA; TREATMENT DURATION; TREATMENT INDICATION; TREATMENT OUTCOME; TREATMENT RESPONSE; TUBERCULOSIS;

EID: 31344480688     PISSN: 01634453     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinf.2005.04.007     Document Type: Article

References (17)

1. S.J. Brickner D.K. Hutchinson M.R. Barbachyn P.R. Manninen D.A. Ulanowicz S.A. Garmon et al. Synthesis and antibacterial activity of U-100592 and U-100766, two oxalidinone antibacterial agents for the potential treatment of multidrug-resistant Gram-positive bacterial infections J Med Chem 39 1996 673-679
2. G.E. Zurenko B.H. Yagi R.D. Schaadt J.W. Allison J.O. Kilburn S.E. Glickman et al. In vitro activities of U-100592 and U-100766 novel oxalidinone antibacterial agents Antimicrob Agents Chemother 40 1996 839-845
3. M.H. Cynamon S.P. Klemens C.A. Sharpe S. Chase Activities of several novel oxalidinones against Mycobacterium tuberculosis in a murine model Antimicrob Agents Chemother 43 1999 1189-1195
4. N.P. Hadjiangelis E. Leibert T.J. Harkin Linezolid: A promising new agent for multidrug resistant tuberculosis treatment Am J Respir Crit Care Med 167 2003 A868
5. R. Norrby Linezolid-a review of the first oxalidinone Exp Opin Pharmacother 2 2001 293-302
6. D. Clemett A. Markham Linezolid Drugs 59 2000 815-827
7. C.B. Inderlid G.E. Pfyffer Susceptibility test mehods: Mycobacteria P.R. Murray E.J. Baron M.A. Pfaller J.H. Jorgensen R.H. Yolken Manual of clinical microbiology 2003 American Society of Microbiology Washington, DC 1161-1163
8. G.E. Pfyffer D.A. Bonato A. Ebrahimzadeh W. Gross J. Hotaling J. Kornblum et al. Multicenter laboratory validation of susceptibility testing of Mycobacterium tuberculosis against classical second-line and newer antimicrobial drugs using the radiometric BACTEC 460 technique and the proportion method with solid media J Clin Microbiol 37 1999 3179-3186
9. P.A. Moise A. Forrest M.C. Birmingham J.J. Schentag The effect and safety of linezolid as treatment for Staphylococcus aureus infections in compassionate use patients who are intolerant of, or have failed to respond to vancomycin J Antimicrob Chemother 50 2003 1017-1026
10. B.A. Lipsky K. Itani C. Norden The Linezolid Diabetic Foot Infections Study Group Treating foot infections in diabetic patients: A randomized, multicenter, open label trial of linezolid versus ampicillin-sulbactam/ ampicillin-clavulanate Clin Infect Dis 38 2003 17-24
11. M.C. Birmingham C.R. Rayner A.K. Meagher S.M. Flavin D.H. Batts J.J. Schentag Linezolid for the treatment of multidrug resistant, Gram-positive infections: Experience from a compassionate-use program Clin Infect Dis 36 2003 159-168
12. D. Toyliss D. Isaacs C. Lander J. McNeil G. Shenfield S. Strasser et al. Linezolid and peripheral neuropathy Aust Adverse Drug React Bull 22 1 2003
13. E. Lee S. Burger J. Shah C. Melton M. Mullen F. Warren et al Linezolid-associated toxic optic neuropathy: A report of 2 cases Clin Infect Dis 37 2003 1389-1391
14. L. Legout E. Senneville J.J. Gomel Y. Yazdanpanah Y. Mouton Linezolid-induced neuropathy Clin Infect Dis 38 2004 767-768
15. P. Tugwell S.L. James Peripheral neuropathy with ethambutol Postgrad Med J 48 1972 667-670
16. V.S. Nair M. LeBrun I. Kass Peripheral neuropathy associated with ethambutol Chest 77 1980 98-100
17. H. Tacheuchi M. Takahashi J. Kang S. Ueno S. Tarui Y. Nakao et al. Ethambutol neuropathy: Clinical and electroneuromyographic studies Folia Psychiatr Neurol Jpn 34 1980 4555