Novel linear diamine disubstituted polycyclic 'cage' derivatives as potential antimycobacterial candidates

Chemical Biology and Drug Design

Volumn 78, Issue 6, 2011, Pages 1022-1030

  Onajole, Oluseye K ^a   Sosibo, Sphelele ^a   Govender, Patrick ^a   Govender, Thavendran ^a   van Helden, Paul D ^b   Maguire, Glenn E M ^a   Mlinarić Majerski, Kata ^c   Wiid, Ian ^b   Kruger, Hendrik G ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

^c RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

Antituberculosis activity; Isoprenyl diamine; Pentacyclodecane; Pentacycloundecane and tricyclodecane; SQ109

Indexed keywords

8,11 DIHYDROXYPENTACYCLO[5.4.0.0 2,6. 3,10 .0 5,9]UNDECANE 8,11 DIACETYLCARBOXAMIDO DIACETIC ACID; [N',N' (8,11 DIHYDROXYPENTACYCLO[5.4.0.0 2,6.3,10 .0 5,9]UNDECANE 8,11 DIETHYLENE)] BIS[(N'' 3,7 DIMETHYLOCTA 2,6 DIENYL)ETHANE 1,2 DIAMINE]; [N',N' (PENTACYCLO[5.3.0.0 2,5 .0 3,9 .0 4,8]DECANE 2,5 DIMETHYLENE)] BIS[(N'' 3,7 DIMETHYLOCTA 2,6 DIENYL)ETHANE 1,2 DIAMINE]; [N',N' (TRICYCLO[3.3.1.1 3,7]DECANE 1,3 DIETHYLENE)] BIS[(N'' 3,7 DIMETHYLOCTA 2,6 DIENYL)ETHANE 1,2 DIAMINE]; [N',N' (TRICYCLO[3.3.1.1 3,7]DECANE 1,3 DIMETHYLENE)] BIS[(N'' 3,7 DIMETHYLOCTA 2,6 DIENYL)ETHANE 1,2 DIAMINE]; [N',N' 3,5 OXAHEXACYCLO[5.4.1.0 2,6 .0 3,10 .0 5,9 .0 8,11]DODECANE 3,5 DIETHYLENE)] BIS[(N'' 3,7 DIMETHYLOCTA 2,6 DIENYL)ETHANE 1,2 DIAMINE]; ADAMANTANE; ANTIMYCOBACTERIAL AGENT; DIAMINE DERIVATIVE; N (2 ADAMANTYL) N' GERANYLETHYLENEDIAMINE; N' (3,7 DIMETHYLOCTA 2,6 DIENYL)ETHANE 1,2 DIAMINE; N',N' BIS(2 OXO 2 METHOXYETHYL) 3,5 OXAHEXACYCLO[5.4.1.0 2,6 .0 3,10 .05,9 .08,11]DODECANE 3,5 DIACETYLCARBOXAMIDE; N',N' BIS(2 OXO 2 METHOXYETHYL) 8,11 DIHYDROXY PENTACYCLO[5.4.0.0 2,6 3,10 .0 5,9]UNDECANE 8,11 DIACETYLCARBOXAMIDE; N',N' BIS(2 OXO 2 METHOXYETHYL)PENTACYCLO[5.3.0.0 2,5 .0 3,9 .0 4,8]DECANE 2,5 DICARBOXAMIDE; N',N' BIS(2 OXO 2 METHOXYETHYL)TRICYCLO[3.3.1.1 3,7]DECANE 1,3 DIACETYLCARBOX AMIDE; N',N' BIS(2 OXO 2 METHOXYETHYL)TRICYCLO[3.3.1.1 3,7]DECANE 1,3 DICARBOXAMIDE; N',N' BIS[2 3,7 DIMETHYLOCTA 2,6 DIENYLAMINO) 2 OXOETHYL] 3,5 OXAHEXACYCLO[5.4.1.0 2,6. 0 3,10 .0 5,9. 0 8,11]DODECANE 3,5 DIMETHYLENECARBOXAMIDE; N',N' BIS[2 3,7 DIMETHYLOCTA 2,6 DIENYLAMINO) 2 OXOETHYL] PENTACYCLO[5.3.0.0 2,5 .0 3,9 .0 4,8]DECANE 2,5 DICARBOXAMIDE; N',N' BIS[2 3,7 DIMETHYLOCTA 2,6 DIENYLAMINO) 2 OXOETHYL] TRICYCLO[3.3.1.1 3,7]DECANE 1,3 DIMETHYLENECARBOXAMIDE; N',N' BIS[2 3,7 DIMETHYLOCTA 2,6 DIENYLAMINO) 2 OXOETHYL]-TRICYCLO[3.3.1.1 3,7]DECANE 1,3 DICARBOXAMIDE; N',N' BIS[2 3,7 DIMETHYLOCTA 2,6DIENYLAMINO) 2 OXOETHYL] 8,11 DIHYDROXYPENTACYCLO[5.4.0.0 2,6.3,10 .0 5,9]UNDECANE 8,11 DIMETHYLENECARBOXAMIDE; OXAHEXACYCLO[5.4.1.0 2,6 .0 3,10 .0 5,9 .0 8,11]DODECANE 3,5 DIACETYLCARBOXAMIDO DIACETIC ACID; PENTACYCLO[5.3.0.0 2,5 .0 3,9 .0 4,8]DECANE 2,5 DICARBOXAMIDO DIACETIC; PENTACYCLODECANE; PENTACYCLOUNDECANE; RICYCLO[3.3.1.1 3,7]DECANE 1,3 DIACETYLCARBOXAMIDODIACETIC ACID; TRICYCLO[3.3.1.1 3,7]DECANE 1,3 DICARBOXAMIDODIACETIC ACID; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

ANTITUBERCULAR AGENTS; DIAMINES; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; POLYCYCLIC COMPOUNDS;

TETRA;

EID: 81355160182     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2011.01242.x     Document Type: Article

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