메뉴 건너뛰기




Volumn 64, Issue , 2013, Pages 137-144

Propranolol restores cognitive deficits and improves amyloid and Tau pathologies in a senescence-accelerated mouse model

Author keywords

A levels; Ageing; BACE1; Hippocampus; IDE; JNK1; SAMP8

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; BETA SECRETASE 1; BRAIN DERIVED NEUROTROPHIC FACTOR; GLYCOGEN SYNTHASE KINASE 3BETA; INSULINASE; PROPRANOLOL; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE 1; SYNAPTOPHYSIN; TAU PROTEIN;

EID: 84866419461     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.06.047     Document Type: Article
Times cited : (57)

References (64)
  • 1
    • 33947155494 scopus 로고    scopus 로고
    • Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats
    • B. Aisa, R. Tordera, B. Lasheras, J. Del Rio, and M.J. Ramirez Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats Psychoneuroendocrinology 32 2007 256 266
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 256-266
    • Aisa, B.1    Tordera, R.2    Lasheras, B.3    Del Rio, J.4    Ramirez, M.J.5
  • 2
    • 0035369189 scopus 로고    scopus 로고
    • Immunohistochemical localization of neprilysin in the human cerebral cortex: Inverse association with vulnerability to amyloid beta-protein (Abeta) deposition
    • H. Akiyama, H. Kondo, K. Ikeda, M. Kato, and P.L. McGeer Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid beta-protein (Abeta) deposition Brain Res. 902 2001 277 281
    • (2001) Brain Res. , vol.902 , pp. 277-281
    • Akiyama, H.1    Kondo, H.2    Ikeda, K.3    Kato, M.4    McGeer, P.L.5
  • 3
    • 0026740795 scopus 로고
    • Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
    • P.V. Arriagada, J.H. Growdon, E.T. Hedley-Whyte, and B.T. Hyman Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease Neurology 42 1992 631 639
    • (1992) Neurology , vol.42 , pp. 631-639
    • Arriagada, P.V.1    Growdon, J.H.2    Hedley-Whyte, E.T.3    Hyman, B.T.4
  • 4
    • 77953675879 scopus 로고    scopus 로고
    • Probing the biology of Alzheimer's disease in mice
    • K.H. Ashe, and K.R. Zahs Probing the biology of Alzheimer's disease in mice Neuron 66 2010 631 645
    • (2010) Neuron , vol.66 , pp. 631-645
    • Ashe, K.H.1    Zahs, K.R.2
  • 5
    • 0028073706 scopus 로고
    • Neurotrophic factors: An evolutionary perspective
    • Y.A. Barde Neurotrophic factors: an evolutionary perspective J. Neurobiol. 25 1994 1329 1333
    • (1994) J. Neurobiol. , vol.25 , pp. 1329-1333
    • Barde, Y.A.1
  • 6
    • 33845930201 scopus 로고    scopus 로고
    • A genotype of exceptional longevity is associated with preservation of cognitive function
    • N. Barzilai, G. Atzmon, C.A. Derby, J.M. Bauman, and R.B. Lipton A genotype of exceptional longevity is associated with preservation of cognitive function Neurology 67 2006 2170 2175
    • (2006) Neurology , vol.67 , pp. 2170-2175
    • Barzilai, N.1    Atzmon, G.2    Derby, C.A.3    Bauman, J.M.4    Lipton, R.B.5
  • 11
    • 79952625346 scopus 로고    scopus 로고
    • Expression of VGLUTs contributes to degeneration and acquisition of learning and memory
    • X.R. Cheng, Y. Yang, W.X. Zhou, and Y.X. Zhang Expression of VGLUTs contributes to degeneration and acquisition of learning and memory Neurobiol. Learn. Mem. 95 2011 361 375
    • (2011) Neurobiol. Learn. Mem. , vol.95 , pp. 361-375
    • Cheng, X.R.1    Yang, Y.2    Zhou, W.X.3    Zhang, Y.X.4
  • 13
    • 33847183893 scopus 로고    scopus 로고
    • Glucocorticoids may initiate Alzheimer's disease: A potential therapeutic role for mifepristone (RU-486)
    • V. Dhikav, and K.S. Anand Glucocorticoids may initiate Alzheimer's disease: a potential therapeutic role for mifepristone (RU-486) Med. Hypotheses 68 2007 1088 1092
    • (2007) Med. Hypotheses , vol.68 , pp. 1088-1092
    • Dhikav, V.1    Anand, K.S.2
  • 14
    • 0023691166 scopus 로고
    • A new one trial-test for neurobiological studies of memory in rats. 1: Behavioral data
    • A. Ennanceur, and J. Delacour A new one trial-test for neurobiological studies of memory in rats. 1: behavioral data Behav. Brain Res. 31 1988 47 59
    • (1988) Behav. Brain Res. , vol.31 , pp. 47-59
    • Ennanceur, A.1    Delacour, J.2
  • 17
    • 0036718272 scopus 로고    scopus 로고
    • Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease
    • H. Fukumoto, B.S. Cheung, B.T. Hyman, and M.C. Irizarry Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease Arch. Neurol. 59 2002 1381 1389
    • (2002) Arch. Neurol. , vol.59 , pp. 1381-1389
    • Fukumoto, H.1    Cheung, B.S.2    Hyman, B.T.3    Irizarry, M.C.4
  • 19
    • 0038326624 scopus 로고    scopus 로고
    • Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment
    • A.L. Guillozet, S. Weintraub, D.C. Mash, and M.M. Mesulam Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment Arch. Neurol. 60 2003 729 736
    • (2003) Arch. Neurol. , vol.60 , pp. 729-736
    • Guillozet, A.L.1    Weintraub, S.2    Mash, D.C.3    Mesulam, M.M.4
  • 20
    • 0032996904 scopus 로고    scopus 로고
    • Low blood pressure and incidence of dementia in a very old sample: Dependent on initial cognition
    • Z. Guo, M. Viitanen, B. Winblad, and L. Fratiglioni Low blood pressure and incidence of dementia in a very old sample: dependent on initial cognition J. Am. Geriatr. Soc. 47 1999 723 726
    • (1999) J. Am. Geriatr. Soc. , vol.47 , pp. 723-726
    • Guo, Z.1    Viitanen, M.2    Winblad, B.3    Fratiglioni, L.4
  • 21
    • 31344454633 scopus 로고    scopus 로고
    • Antihypertensive agents for aging patients who are at risk for cognitive dysfunction
    • I. Hajjar, M. Keown, and B. Frost Antihypertensive agents for aging patients who are at risk for cognitive dysfunction Curr. Hypertens. 7 2005 466 473
    • (2005) Curr. Hypertens. , vol.7 , pp. 466-473
    • Hajjar, I.1    Keown, M.2    Frost, B.3
  • 22
    • 0021275014 scopus 로고
    • Grading score system: A method for evaluation of the degree of senescence in senescence accelerated mouse (SAM)
    • H. Hamamoto, A. Honma, M. Irino, T. Matsushita, K. Toda, M. Matsumura, and T. Takeda Grading score system: a method for evaluation of the degree of senescence in senescence accelerated mouse (SAM) Mech. Ageing Dev. 26 1984 91 102
    • (1984) Mech. Ageing Dev. , vol.26 , pp. 91-102
    • Hamamoto, H.1    Honma, A.2    Irino, M.3    Matsushita, T.4    Toda, K.5    Matsumura, M.6    Takeda, T.7
  • 23
    • 84856990182 scopus 로고    scopus 로고
    • Strategies, development, and pitfalls of therapeutic options for Alzheimer's disease
    • C. Haas Strategies, development, and pitfalls of therapeutic options for Alzheimer's disease J. Alzheimers Dis. 28 2012 241 281
    • (2012) J. Alzheimers Dis. , vol.28 , pp. 241-281
    • Haas, C.1
  • 26
    • 11844251260 scopus 로고    scopus 로고
    • Regulation of gene expression by the amyloid precursor protein: Inhibition of the JNK/cJun pathway
    • D. Kögel, R. Schomburg, E. Copanaki, and J.H. Prehn Regulation of gene expression by the amyloid precursor protein: inhibition of the JNK/cJun pathway Cell. Death Differ. 12 2005 1 9
    • (2005) Cell. Death Differ. , vol.12 , pp. 1-9
    • Kögel, D.1    Schomburg, R.2    Copanaki, E.3    Prehn, J.H.4
  • 27
    • 0034867485 scopus 로고    scopus 로고
    • Site directed antisense oligonucleotides decrease the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice
    • B.V. Kumar, S.A. Farr, J.F. Flood, K. Vyas, M. Franko, W.A. Banks, and J.E. Morley Site directed antisense oligonucleotides decrease the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice Peptides 21 2000 1769 1775
    • (2000) Peptides , vol.21 , pp. 1769-1775
    • Kumar, B.V.1    Farr, S.A.2    Flood, J.F.3    Vyas, K.4    Franko, M.5    Banks, W.A.6    Morley, J.E.7
  • 28
    • 0028176821 scopus 로고
    • Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme
    • I.V. Kurochkin, and S. Goto Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme FEBS Lett. 345 1994 33 37
    • (1994) FEBS Lett. , vol.345 , pp. 33-37
    • Kurochkin, I.V.1    Goto, S.2
  • 29
    • 0032609465 scopus 로고    scopus 로고
    • Making the connection: Coupling of stress-activated ERK/MAPK (extracellular-signal-regulated kinase/mitogen-activated protein kinase) core signalling modules to extracellular stimuli and biological responses
    • J.M. Kyriakis Making the connection: coupling of stress-activated ERK/MAPK (extracellular-signal-regulated kinase/mitogen-activated protein kinase) core signalling modules to extracellular stimuli and biological responses Biochem. Soc. Symp. 64 1999 29 48
    • (1999) Biochem. Soc. Symp. , vol.64 , pp. 29-48
    • Kyriakis, J.M.1
  • 30
    • 70149095473 scopus 로고    scopus 로고
    • Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Abeta1-42 oligomers and upregulating synaptic plasticity-related proteins in the hippocampus
    • Q. Li, H.F. Zhao, Z.F. Zhang, Z.G. Liu, X.R. Pei, J.B. Wang, and Y. Li Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Abeta1-42 oligomers and upregulating synaptic plasticity-related proteins in the hippocampus Neuroscience 163 2009 741 749
    • (2009) Neuroscience , vol.163 , pp. 741-749
    • Li, Q.1    Zhao, H.F.2    Zhang, Z.F.3    Liu, Z.G.4    Pei, X.R.5    Wang, J.B.6    Li, Y.7
  • 31
    • 84855806746 scopus 로고    scopus 로고
    • MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice
    • W. Liu, C. Liu, J. Zhu, P. Shu, B. Yin, Y. Gong, B. Qiang, J. Yuan, and X. Peng MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice Neurobiol. Aging 33 2010 522 534
    • (2010) Neurobiol. Aging , vol.33 , pp. 522-534
    • Liu, W.1    Liu, C.2    Zhu, J.3    Shu, P.4    Yin, B.5    Gong, Y.6    Qiang, B.7    Yuan, J.8    Peng, X.9
  • 32
    • 23844522541 scopus 로고    scopus 로고
    • Aggregation of vascular risk factors and risk of incident Alzheimer disease
    • J.A. Luchsinger, C. Reitz, L.S. Honig, M.X. Tang, S. Shea, and R. Mayeux Aggregation of vascular risk factors and risk of incident Alzheimer disease Neurology 65 2005 545 551
    • (2005) Neurology , vol.65 , pp. 545-551
    • Luchsinger, J.A.1    Reitz, C.2    Honig, L.S.3    Tang, M.X.4    Shea, S.5    Mayeux, R.6
  • 34
    • 65649111733 scopus 로고    scopus 로고
    • Stress-activated MAP kinase cascades in cellular senescence
    • J. Maruyama, I. Naguro, K. Takeda, and H. Ichijo Stress-activated MAP kinase cascades in cellular senescence Curr. Med. Chem. 16 2009 1229 1235
    • (2009) Curr. Med. Chem. , vol.16 , pp. 1229-1235
    • Maruyama, J.1    Naguro, I.2    Takeda, K.3    Ichijo, H.4
  • 35
    • 0031044352 scopus 로고    scopus 로고
    • Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: Involvement of insulin-degrading enzyme
    • J.R. McDermott, and A.M. Gibson Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme Neurochem. Res. 22 1997 49 56
    • (1997) Neurochem. Res. , vol.22 , pp. 49-56
    • McDermott, J.R.1    Gibson, A.M.2
  • 36
    • 34548703093 scopus 로고    scopus 로고
    • Amyloid beta protein as a marker or risk factor of Alzheimer's disease
    • P.D. Mehta Amyloid beta protein as a marker or risk factor of Alzheimer's disease Curr. Alzheimer Res. 4 2007 359 363
    • (2007) Curr. Alzheimer Res. , vol.4 , pp. 359-363
    • Mehta, P.D.1
  • 37
    • 33749475139 scopus 로고    scopus 로고
    • Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy
    • J.S. Miners, Z. Van Helmond, K. Chalmers, G. Wilcock, S. Love, and P.G. Kehoe Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy J. Neuropathol. Exp. Neurol. 65 2006 1012 1021
    • (2006) J. Neuropathol. Exp. Neurol. , vol.65 , pp. 1012-1021
    • Miners, J.S.1    Van Helmond, Z.2    Chalmers, K.3    Wilcock, G.4    Love, S.5    Kehoe, P.G.6
  • 39
    • 79952182383 scopus 로고    scopus 로고
    • Potential therapeutic uses of BDNF in neurological and psychiatric disorders
    • A.H. Nagahara, and M.H. Tuszynsk Potential therapeutic uses of BDNF in neurological and psychiatric disorders Nat. Rev. Drug Discov. 10 2011 209 219
    • (2011) Nat. Rev. Drug Discov. , vol.10 , pp. 209-219
    • Nagahara, A.H.1    Tuszynsk, M.H.2
  • 40
    • 84855784511 scopus 로고    scopus 로고
    • Sildenafil ameliorates cognitive deficits and tau pathology in a senescence-accelerated mouse model
    • 625.e11-20
    • L. Orejana, L. Barros-Miñones, J. Jordán, E. Puerta, and N. Aguirre Sildenafil ameliorates cognitive deficits and tau pathology in a senescence-accelerated mouse model Neurobiol. Aging 33 2012 625.e11-20
    • (2012) Neurobiol. Aging , vol.33
    • Orejana, L.1    Barros-Miñones, L.2    Jordán, J.3    Puerta, E.4    Aguirre, N.5
  • 41
    • 58149380018 scopus 로고    scopus 로고
    • From aging to Alzheimer's disease: Unveiling "the switch" with the senescence-accelerated mouse model (SAMP8)
    • M. Pallas, A. Camins, M.A. Smith, G. Perry, H.G. Lee, and G. Casadesus From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8) J. Alzheimers Dis. 15 2008 615 624
    • (2008) J. Alzheimers Dis. , vol.15 , pp. 615-624
    • Pallas, M.1    Camins, A.2    Smith, M.A.3    Perry, G.4    Lee, H.G.5    Casadesus, G.6
  • 42
    • 33845883559 scopus 로고    scopus 로고
    • Age-related disruptions of circadian rhythm and memory in the senescence-accelerated mouse (SAM8)
    • K.C.H. Pang, J.P. Miller, A. Fortress, and D. McAuley Age-related disruptions of circadian rhythm and memory in the senescence-accelerated mouse (SAM8) Age 28 2006 283 296
    • (2006) Age , vol.28 , pp. 283-296
    • Pang, K.C.H.1    Miller, J.P.2    Fortress, A.3    McAuley, D.4
  • 43
    • 33646374182 scopus 로고    scopus 로고
    • Activated c-Jun is present in neurofibrillary tangles in Alzheimer's disease brains
    • A.G. Pearson, U.T. Byrne, G.A. MacGibbon, R.L. Faull, and M. Dragunow Activated c-Jun is present in neurofibrillary tangles in Alzheimer's disease brains Neurosci. Lett. 398 2006 246 250
    • (2006) Neurosci. Lett. , vol.398 , pp. 246-250
    • Pearson, A.G.1    Byrne, U.T.2    MacGibbon, G.A.3    Faull, R.L.4    Dragunow, M.5
  • 44
    • 84859766854 scopus 로고    scopus 로고
    • Management of hypertension in the elderly
    • E. Pimenta, and S. Oparil Management of hypertension in the elderly Nat. Rev. Cardiol. 9 2012 286 296
    • (2012) Nat. Rev. Cardiol. , vol.9 , pp. 286-296
    • Pimenta, E.1    Oparil, S.2
  • 46
    • 40449086665 scopus 로고    scopus 로고
    • Dose translation from animal to human studies revisited
    • S. Reagan-Shaw, M. Nihal, and N. Ahmad Dose translation from animal to human studies revisited FASEB J. 22 2007 659 661
    • (2007) FASEB J. , vol.22 , pp. 659-661
    • Reagan-Shaw, S.1    Nihal, M.2    Ahmad, N.3
  • 47
    • 4644288235 scopus 로고    scopus 로고
    • Glucocorticoid effects on memory retrieval require concurrent noradrenergic activity in the hippocampus and basolateral amygdala
    • B. Roozendaal, E.L. Hahn, S.V. Nathan, D.J. de Quervain, and J.L. McGaugh Glucocorticoid effects on memory retrieval require concurrent noradrenergic activity in the hippocampus and basolateral amygdala J. Neurosci. 24 2004 8161 8169
    • (2004) J. Neurosci. , vol.24 , pp. 8161-8169
    • Roozendaal, B.1    Hahn, E.L.2    Nathan, S.V.3    De Quervain, D.J.4    McGaugh, J.L.5
  • 48
    • 27544432457 scopus 로고    scopus 로고
    • Neprylisin decreases uniformly in Alzheimer's disease and in normal aging
    • R. Russo, R. Borghi, W. Markesbery, M. Tabaton, and A. Piccini Neprylisin decreases uniformly in Alzheimer's disease and in normal aging FEBS Lett. 579 2005 6027 6030
    • (2005) FEBS Lett. , vol.579 , pp. 6027-6030
    • Russo, R.1    Borghi, R.2    Markesbery, W.3    Tabaton, M.4    Piccini, A.5
  • 50
    • 0033813571 scopus 로고    scopus 로고
    • Neurotrophic factors in Alzheimer's and Parkinson's disease brain
    • G.J. Siegel, and N.B. Chauhan Neurotrophic factors in Alzheimer's and Parkinson's disease brain Brain Res. Rev. 33 2000 199 227
    • (2000) Brain Res. Rev. , vol.33 , pp. 199-227
    • Siegel, G.J.1    Chauhan, N.B.2
  • 51
    • 33646493486 scopus 로고    scopus 로고
    • Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8
    • F.X. Sureda, J. Gutierrez-Cuesta, M. Romeu, M. Mulero, A.M. Canudas, A. Camins, J. Mallol, and M. Pallàs Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8 Exp. Gerontol. 41 2006 360 367
    • (2006) Exp. Gerontol. , vol.41 , pp. 360-367
    • Sureda, F.X.1    Gutierrez-Cuesta, J.2    Romeu, M.3    Mulero, M.4    Canudas, A.M.5    Camins, A.6    Mallol, J.7    Pallàs, M.8
  • 53
    • 0032847560 scopus 로고    scopus 로고
    • Senescence-accelerated mouse (SAM): A biogerontological resource in aging research
    • T. Takeda Senescence-accelerated mouse (SAM): a biogerontological resource in aging research Neurobiol. Aging 20 1999 105 110
    • (1999) Neurobiol. Aging , vol.20 , pp. 105-110
    • Takeda, T.1
  • 58
    • 0035813199 scopus 로고    scopus 로고
    • Protein synthesis-dependent and -independent regulation of hippocampal synapses by brain-derived neurotrophic factor
    • N. Tartaglia, J. Du, W.J. Tyler, E. Neale, L. Pozzo-Miller, and B. Lu Protein synthesis-dependent and -independent regulation of hippocampal synapses by brain-derived neurotrophic factor J. Biol. Chem. 276 2001 37585 37593
    • (2001) J. Biol. Chem. , vol.276 , pp. 37585-37593
    • Tartaglia, N.1    Du, J.2    Tyler, W.J.3    Neale, E.4    Pozzo-Miller, L.5    Lu, B.6
  • 59
    • 62349133406 scopus 로고    scopus 로고
    • Neurochemistry, neuropathology, and heredity in SAMP8: A mouse model of senescence
    • K. Tomobe, and Y. Nomura Neurochemistry, neuropathology, and heredity in SAMP8: a mouse model of senescence Neurochem. Res. 34 2009 660 669
    • (2009) Neurochem. Res. , vol.34 , pp. 660-669
    • Tomobe, K.1    Nomura, Y.2
  • 60
    • 1842714295 scopus 로고    scopus 로고
    • Synaptophysin: Leading actor or walk-on role in synaptic vesicle exocytosis?
    • F. Valtorta, M. Pennuto, D. Bonanomi, and F. Benfenati Synaptophysin: leading actor or walk-on role in synaptic vesicle exocytosis? Bioessays 26 2004 445 453
    • (2004) Bioessays , vol.26 , pp. 445-453
    • Valtorta, F.1    Pennuto, M.2    Bonanomi, D.3    Benfenati, F.4
  • 61
    • 33748295795 scopus 로고    scopus 로고
    • Insulin signaling in the central nervous system: Learning to survive
    • L.P. van der Heide, G.M. Ramakers, and M.P. Smidt Insulin signaling in the central nervous system: learning to survive Prog. Neurobiol. 79 2006 205 221
    • (2006) Prog. Neurobiol. , vol.79 , pp. 205-221
    • Van Der Heide, L.P.1    Ramakers, G.M.2    Smidt, M.P.3
  • 62
    • 0034161516 scopus 로고    scopus 로고
    • Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme
    • K. Vekrellis, Z. Ye, W.Q. Qiu, D. Walsh, D. Hartley, V. Chesneau, M.R. Rosner, and D.J. Selkoe Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme J. Neurosci. 20 2000 1657 1665
    • (2000) J. Neurosci. , vol.20 , pp. 1657-1665
    • Vekrellis, K.1    Ye, Z.2    Qiu, W.Q.3    Walsh, D.4    Hartley, D.5    Chesneau, V.6    Rosner, M.R.7    Selkoe, D.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.