The effects of Tabernaemontana divaricata root extract on amyloid β-peptide 25-35 peptides induced cognitive deficits in mice

Journal of Ethnopharmacology

Volumn 130, Issue 1, 2010, Pages 122-126

  Nakdook, Walika ^a   Khongsombat, Onrawee ^a   Taepavarapruk, Pornnarin ^a   Taepavarapruk, Niwat ^a   Ingkaninan, Kornkanok ^a  

^a NARESUAN UNIVERSITY   (Thailand)

Author keywords

Acetylcholinesterase activity; Amyloid peptide; Cognitive deficits; Tabernaemontana divaricata

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID BETA PROTEIN[25-35]; PLANT EXTRACT; TABERNAEMONTANA DIVARICATA EXTRACT; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (25-35); PEPTIDE FRAGMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN LEVEL; COGNITIVE DEFECT; COLORIMETRY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HERB; HIPPOCAMPUS; MAZE TEST; MEDICINAL PLANT; MEMORY DISORDER; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PLANT ROOT; REJUVENATION; SPATIAL MEMORY; TABERNAEMONTANA DIVARICATA; TASK PERFORMANCE; THAILAND; TREATMENT OUTCOME; ANIMAL; CHEMISTRY; COGNITION DISORDERS; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; MALE; METABOLISM; TABERNAEMONTANA;

ACETYLCHOLINESTERASE; AMYLOID BETA-PROTEIN; ANIMALS; COGNITION DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; MALE; MAZE LEARNING; MICE; MICE, INBRED ICR; PEPTIDE FRAGMENTS; PLANT EXTRACTS; PLANT ROOTS; TABERNAEMONTANA; AMYLOID BETA-PEPTIDES;

MUS; TABERNAEMONTANA DIVARICATA;

EID: 77953811011     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.04.027     Document Type: Article

References (33)

1. Alvarez A., Alarcon R., Opazo C., Campos E.O., Munoz F.J., Calderon F.H., et al. Stable complexes involving acetylcholinesterase and amyloid-β peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils. Journal of Neuroscience 1998, 18:3213-3223.
2. Chattipakorn S., Pongpanparadorn A., Pratchayasakul W., Pongchaidacha A., Ingkaninan K., Chattipakorn N. Tabernaemontana divaricata extract inhibits neuronal acetylcholinesterase activity in rats. Journal of Ethnopharmacology 2007, 110:61-68.
3. Delobette S., Privat A., Maurice T. In vitro aggregation facilitates β-amyloid peptide-25-35-induced amnesia in the rat. European Journal of Pharmacology 1997, 319:1-4.
4. D'Hooge R., De Deyn P.P. Application of the Morris water maze in the study of learning and memory. Brain Research Review 2001, 36:60-90.
5. Ellman G.L., Lourtney D.K., Andres V., Gmelin G. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology 1961, 7:88-95.
6. Fu A.L., Dong Z.H., Sun M.J. Protective effect of N-acetyl-l-cysteine on amyloid β-peptide-induced learning and memory deficits in mice. Brain Research 2006, 1109:201-206.
7. Fu A.L., Dong Z.H., Sun M.J. Protective effect of recombinant human somatotropin on amyloid β-peptide induced learning and memory deficits in mice. Growth Hormone & IGF Research 2007, 17:336-341.
8. Gage F., Bjorklund A. Cholinergic septum grafts into the hippocampal formation improve spatial learning and memory in aged rats by an atropine-sensitive mechanism. Journal of Neuroscience 1986, 6:2837-2847.
9. Geula C., Mesulam M.M. Cholinergic systems and related neuropathological predilection patterns in Alzheimer disease. Alzheimer Disease 1994, 263-291. Raven Press, New York. R.D. Terry, R. Katzman, K.L. Bick (Eds.).
10. Haley T.J., McCormick W.J. Pharmacological effects produced by intracerebral injections of drugs in the conscious mouse. British Journal of Pharmacology 1957, 12:12-15.
11. Henriques A.T., Melo A.A., Moreno P.R., Ene L.L., Henriques J.A., Schapoval E.E. Ervatamia coronaria: chemical constituents and some pharmacological activities. Journal of Ethnopharmacology 1996, 50:19-25.
12. Inestrosa N.C., Alvarez A., Pérez C.A., Moreno R.D., Vicente M., Linker C., et al. Acetylcholinesterase accelerates assembly of amyloid β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron 1996, 16:881-891.
13. Ingkaninan K., Changwijit K., Suwanborirux K. Vobasinyl-iboga bisindole alkaloids, potent acetylcholinesterase inhibitors from Tabernaemontana divaricata root. Journal of Pharmacy and Pharmacology 2006, 58:847-852.
14. Ingkaninan K., Temkitthawon P., Chuenchom K., Yuyaem T., Thongnoi W. Screening for acetylcholinesterase inhibitory activity in plants used in Thai traditional rejuvenating and neurotonic remedies. Journal of Ethnopharmacology 2003, 89:261-264.
15. Katzman R. Alzheimer's disease. New England Journal of Medicine 1986, 314:964-973.
16. Kuo Y.C., Sun C.M., Tsai W.J., Ou J.C., Chen W.P., Lin C.Y. Blocking of cell proliferation, cytokines production and gene expression following administration of Chinese herb in the human mesangial cells. Life Science 1999, 64:2089-2099.
17. Luo J., Yin J.H., Wei Y.Q. The effect of calcineurin activator, extracted from Chinese herbal medicine, on memory and immunity in mice. Pharmacology Biochemistry and Behavior 2003, 75:749-754.
18. Maurice T., Lockhart B.P., Privat A. Amnesia induced in mice by centrally administered β-amyloid peptides involves cholinergic dysfunction. Brain Research 1996, 706:181-193.
19. Melo A.A., Querol C.B., Henriques A.T., Henriques J.A. Cytostatic, cytotoxic and mutagenic effect of voacristine, an indole alkaloid in wide-type and repair-deficient yeasts. Mutation Research 1986, 171:17-24.
20. Melo J.B., Agostinho P., Oliveira C.R. Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide. Neuroscience Research 2003, 45:117-127.
21. Moran M.A., Mufson E.J., Gomez R.P. Colocalization of cholinesterases with β amyloid protein in aged and Alzheimer's brains. Acta Neuropathologica 1993, 85:362-369.
22. Morris R.G.M. Development of a water-maze procedure for studying spatial learning in the rat. Journal of Neuroscience Methods 1984, 11:47-60.
23. O'Mahony S., Harkany T., Rensink A.A.M., Abraham I., De Jong G.I., Varga J.L. β-Amyloid-induced cholinergic denervation correlates with enhanced nitric oxide synthase activity in rat cerebral cortex: reversal by NMDA receptor blockade. Brain Research Bulletin 1998, 45:405-411.
24. Pratchayasakul W., Pongchaidecha A., Chattipakorn N., Chattipakorn S. Ethnobotany & ethnopharmacology of Tabernaemontana divaricata. The Indian Journal of Medical Research 2008, 127:317-335.
25. Stepanichev M., Lazareva N.A., Onufriev M.V., Mitrokhina O.S., Moiseeva Y.V., Gulyaeva N.V. The effect of the administration of beta-amyloid peptide fragment (25-35) on behavior in rats. Zhurnal vyssheǐ nervnoǐ deiatelnosti imeni I P Pavlova 1997, 47:597-600.
26. Stepanichev M.Y., Moiseeva Y.V., Lazareva N.A., Onufriev M.V., Gulyaeva N.V. Single intracerebroventricular administration of amyloid-beta (25-35) peptide induces impairment in short-term rather than long-term memory in rats. Brain Research Bulletin 2003, 61:197-205.
27. Taesotikul T., Panthong A., Kanjanapothi D., Verpoorte R., Scheffer J.J.C. Hippocratic screening of ethanolic extracts from two Tabernaemontana species. Journal of Ethnopharmacology 1989, 27:99-106.
28. Taesotikul T., Panthong A., Kanjanapothi D., Verpoorte R., Scheffer J.J.C. Cardiovascular effects of Tabernaemontana pandacaqui. Journal of Ethnopharmacology 1989, 27:107-119.
29. Ulrich J., Meier-Ruge W., Probst A., Meier E., Ipsen S. Senile plaques: staining for acetylcholinesterase and A4 protein: a comparative study in the hippocampus and entorhinal cortex. Acta Neuropathologica 1990, 80:624-628.
30. Um M.Y., Choi W.H., Aan J.Y., Kim S.R., Ha T.Y. Protective effect of Polygonum multiflorum Thunb on amyloid β-peptide 25-35 induced cognitive deficits in mice. Journal of Ethnopharmacology 2006, 104:144-148.
31. Van Beek T.A., Verpoorte R., Kinh P.Q. Pseudovobparicine, a new dimeric indole alkaloid from Tabernaemontana divaricata. Planta Medica 1985, 3:277-279.
32. Yamada N., Hattori A., Hayashi T., Nishikawa T., Fukuda H., Fujino T. Improvement of scopolamine-induced memory impairment by Z-ajoene in the water maze in mice. Pharmacology Biochemistry and Behavior 2004, 78:787-791.
33. Yamaguchi Y., Kawashima S. Effects of amyloid-β-(25-35) on passive avoidance, radial-arm maze learning and choline acetyltransferase activity in the rat. European Journal of Pharmacology 2001, 412:265-272.