Application of membrane permeability evaluated in in vitro analyses to estimate blood-retinal barrier permeability

Journal of Pharmaceutical Sciences

Volumn 101, Issue 7, 2012, Pages 2596-2605

  Kubo, Yoshiyuki ^a   Fukui, Eri ^a   Akanuma, Shin Ichi ^a   Tachikawa, Masanori ^a,b   Hosoya, Ken Ichi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

in vitro in vivo correlations (IVIVC); Membrane transport; Membrane transporter; Passive diffusion transport; Permeability; Retinal drug delivery

Indexed keywords

ADENOSINE; ARGININE; CORTICOSTERONE; CREATININE; DIAZEPAM; DIGOXIN; DOPAMINE; GLUCOSE; GLYCINE; LEUCINE; LEVACECARNINE; LEVODOPA; MANNITOL; PHENAZONE; PHENYLALANINE; PROGESTERONE; TESTOSTERONE; URACIL; VALPROIC ACID; VERAPAMIL; VINCRISTINE; WARFARIN; DRUG;

ARTICLE; BLOOD RETINA BARRIER; CELL CULTURE; CELL LINE; DIFFUSION; DRUG PENETRATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPOPHILICITY; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; RETINA CELL; ANIMAL; ARTIFICIAL MEMBRANE; CELL MEMBRANE PERMEABILITY; CHEMISTRY; CYTOLOGY; METABOLISM; PHARMACOKINETICS; RAT; RETINA; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-RETINAL BARRIER; CELL LINE; CELL MEMBRANE PERMEABILITY; DIFFUSION; ENDOTHELIAL CELLS; MEMBRANES, ARTIFICIAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; RATS; RETINA;

EID: 84866295000     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23171     Document Type: Article

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