Identification and functional characterization of the first nucleobase transporter in mammals: Implication in the species difference in the intestinal absorption mechanism of nucleobases and their analogs between higher primates and other mammals

Journal of Biological Chemistry

Volumn 285, Issue 9, 2010, Pages 6522-6531

  Yamamoto, Syunsuke ^a   Inoue, Katsuhisa ^a   Murata, Tomoaki ^a   Kamigaso, Syunsuke ^a   Yasujima, Tomoya ^a   Maeda, Jun Ya ^a   Yoshida, Yukihiro ^a   Ohta, Kin Ya ^a   Yuasa, Hiroaki ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5-FLUOROURACIL; APICAL MEMBRANES; FUNCTIONAL CHARACTERIZATION; GREEN FLUORESCENT PROTEIN; HEK293 CELLS; INHIBITORY EFFECT; INTESTINAL ABSORPTION; MADIN-DARBY CANINE KIDNEYS; MICHAELIS CONSTANTS; MOLECULAR ENTITIES; NUCLEOBASES; SMALL INTESTINE; THERAPEUTIC USE; TRANSPORT SYSTEMS;

ABSORPTION; BIOMOLECULES; METABOLISM; NUCLEIC ACIDS; SODIUM;

MAMMALS;

CYTOSINE; FLUOROURACIL; GREEN FLUORESCENT PROTEIN; GUANINE; HYPOXANTHINE; MESSENGER RNA; NUCLEOBASE TRANSPORTER; NUCLEOSIDE; PROTEIN SLC23A4; THYMINE; UNCLASSIFIED DRUG; URACIL; XANTHINE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; SLC23A4 PROTEIN, RAT; SODIUM;

AMINO ACID TRANSPORT; ANIMAL CELL; APICAL MEMBRANE; ARTICLE; CELL STRAIN; CELL STRAIN HEK293; CONTROLLED STUDY; HUMAN; HUMAN CELL; MADIN DARBY CANINE KIDNEY CELL; MICHAELIS CONSTANT; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; ANIMAL; CELL LINE; DOG; ENZYME SPECIFICITY; INTESTINE ABSORPTION; KINETICS; METABOLISM; MOLECULAR GENETICS; RAT; SPECIES DIFFERENCE;

MAMMALIA; PRIMATES; RATTUS;

ANIMALS; CELL LINE; DOGS; HUMANS; INTESTINAL ABSORPTION; KINETICS; MOLECULAR SEQUENCE DATA; NUCLEOBASE TRANSPORT PROTEINS; PURINES; PYRIMIDINES; RATS; SODIUM; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; URACIL;

EID: 77949877904     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.032961     Document Type: Article

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